1.A Study on Socio-demographic and Cultural Factors of Spousal Violence
Shaohong ZOU ; Yalin ZHANG ; Yong ZHANG
Chinese Journal of Clinical Psychology 2001;0(03):-
Objective: To investigate the socio-demographic and cultural factors of spousal violence(SV) in order to provide systematic basis of SV prevention.Methods: By using multistage stratified sampling methods,3087 households were selected from Chenzhou city in Hunan Province.After screening,384 households had SV.Among them 80 households were randomly selected for study,in which 80 perpetrators were not in the domestic violence(DV) group.For the non-DV group,after matching of family’s structure,96 households without violence behavior were selected,in which after matching of gender and age with perpetrators,96 normal controls were enrolled.Results: The ratio of male perpetrators(81.3%) was more than female(18.7%),but female(81.3%) was more than male(19%) victims(P
2.Psychosocial Characteristics of Spousal Violence in Hunan
Shaohong ZOU ; Yalin ZHANG ; Yuping CAO
Chinese Mental Health Journal 1991;0(05):-
Objective:To investigate the psychosocial characteristics of the perpetrators and the victims of spouse violence (SV).Methods:80 families with a history of SV were randomly selected from communities, and their psychosocial characteristics were compared with control group of 96 non-SV families matched for family structure. A self-designed SV questionnaire, the self-report Symptom Checklist-90 (SCL-90), Eysenck's Personality Questionnaire (EPQ), Trait Coping Style and Questionnaire (TCSQ) were used in this cross-sectional survey.Results:65 husbands and 15 wives were identified as perpetrators, correspondingly 65 wives and 15 husbands as victims. The total score and factors scores of SCL-90, EPQ-N score, and scores of subjective social support, objective support and total supports were higher in perpetrators than their counterparts in control group. Negative coping style and EPQ-P score were respectively higher and lower in perpetrators than victims of SV (29.6?8.3/29.5?7.4,t=2.127, P
3.X-ray diagnosis of salpingian diverticulum--a report of 7 cases.
Shaohong, CHEN ; Hui, CHEN ; Qingmei, ZHANG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2002;22(1):87-8
Seven cases of typical salpingian diverticulum were identified by hysterosalpinography (HSG). The differentiation diagnosis of the disease was discussed. HSG is believed to be the method of choice for the diagnosis of this disease.
Adnexal Diseases/*radiography
;
Diagnosis, Differential
;
Diverticulum/*radiography
;
*Fallopian Tubes
;
Hysterosalpingography
4.Separation and purification of B-Phycoerythrin in Porphyridium cruentum
Shaohong WEN ; Chenglong ZHAO ; Liping ZHANG ;
Chinese Journal of Marine Drugs 1994;0(03):-
The B Phycoerythrin(B PE) could both be separated after crude phycobiliproteins from Porphyridium cruentum were precipitated in ammonium sulphate and dialyzed,then chromatographed on a hydroxylapatite (HA) Column and a Sephadex G 100 column respectively.The purity of B PE separated by two methods was 4.92 and 3.78 (A 545 nm/A 280 nm) respectively.When the purified B PE was electrophoresed under polyacryiamide gradient gel electrophoresis condition,only one band was observed.The B PE possessed an absorption maximum at 545nm and a room fluoresence emission at 574.5nm.
5.Practice on delicacy management of hospital logistics services
Jianchang WANG ; Shaohong LU ; Zebiao ZHANG ; Baofeng FAN
Chinese Journal of Hospital Administration 2011;27(10):790-792
Delicacy management is an important issue to the hospital logistics mode innovation,which is the only way to realize a scientific hospital logistics management.This article proposes the practical ways to push on the hospital logistics delicacy management from many respects,such as working regulation,consumption measurement,contract supervision,cost accounting,structure control and convergence supporting.
6.Transplantation of bone marrow mesenchymal stem cells affects the proliferation and function of CD4+T cells in mice
Shaohong SU ; Junfeng ZHANG ; Qianru LI ; Shasha GUAN ; Ying DU
Chinese Journal of Tissue Engineering Research 2014;(1):106-111
BACKGROUND:Mesenchymal stem cells are found to have the immunoregulatory activities and a potential application prospect in the treatment of autoimmune diseases.
OBJECTIVE:To explore the mechanism of transplanting mesenchymal stems cells on the treatment of multiple sclerosis.
METHODS:The mouse mesenchymal stems cells were prepared, and injected into the al ogenic and syngenic normal mice, to detect the frequency of CD4+CD25+Foxp3+T cells in the spleen, thymus, and lymph nodes by flow cytometry, and to detect the Foxp3, transforming growth factor-β1, and interleukin-10 mRNA in the spleen, thymus, and lymph nodes by reverse transcription-PCR.
RESULTS AND CONCLUSION:Transplantation of mesenchymal stem cells on normal mice led to a significant up-regulation of CD4+CD25+Foxp3+T cells, Foxp3, transforming growth factor-β1, and interleukin-10 mRNA in the spleen, thymus, and lymph nodes both in the al ogenic and syngenic transplant groups. Transplantation of mesenchymal stem cells may be an available method in the treatment of autoimmune diseases, and CD4+CD25+Foxp3+T cell, Foxp3, transforming growth factor-β1, and interleukin-10 may be involved in this process.
7.An association analysis between polymorphism of glutamate receptor 6 gene and impulsively aggressive behavior in patients with bipolar disorder
Wei HU ; Shaohong ZOU ; Zongfeng ZHAO ; Gaiyu TONG ; Yi ZHANG
Journal of Chinese Physician 2017;19(5):664-666
Objective To explore the association between impulsively aggressive behavior and rs6922753 single nucleotide polymorphism of glutamate receptor 6 (GluR6) gene in Xinjiang Uygur and Han patients with bipolar disorder.Methods The techniques of polymerase chain reaction (PCR) and DNA sequencing technique were conducted to detect rs6922753 single nucleotide polymorphism of GluR6 gene in 240 patients with bipolar disorder.The association between the polymorphisms and impulsively aggressive behavior was analyzed with SPSS 17.0 software.Results No statistical difference was observed between the impulsively aggressive behavior group and the no impulsively aggressive behavior group of Xinjiang Han and Uygur patients with bipolar disorder in the genotype and allele frequencies for the investigated rs6922753 polymorphisms (P > 0.05).Conclusions No association was found between the impulsively aggressive behavior and rs6922753 single nucleotide polymorphism of GluR6 gene in Xinjiang Uygur and Han patients with bipolar disorder.
8.Resistance and Serotype of 152 Strains of Streptococcus pneumoniae
Jing ZHANG ; Ziyong SUN ; Yue MA ; Jingyun LI ; Shaohong JIN
Chinese Journal of Nosocomiology 1994;0(04):-
OBJECTIVE To investigate antibiotic resistance and the prevalence of serotype of Streptococcus pneumoniae in Wuhan.METHODS Totally 152 strains of S.pneumoniae were collected to test the MICs of various antibiotics by agar dilution method according to the approved standard of NCCLS.Serotyping of S.pneumoniae was performed by using quelling reaction.RESULTS Among 152 strains of S.pneumoniae,65(42.76%) strains were resistant to penicillin(MIC≥0.12mg/L).94.08%,50.66%,41.45% and 11.18% of S.pneumoniae were resistant against the first(cefalexin),second(cefaclor) and third(cefaxime and ceftriaxone) generation of cephalosporins respectively.The resistance rates to other antibiotic agents,such as erythromycin,tetracycline,trimethoprim/sulfamethoxazole and chloramphenicol,were 84.21%,88.82%,89.47% and 18.42%,respectively.Strains that were resistant to levofloxacin and moxifloxacin were found both for 1.32%.Twenty serotypes were involved in 152 strains. The prevalent serotypes were 19(25.66%),23(19.08%),6(13.82%),15(7.24%)and 14(4.61%).Eight strains were remained for unable to serotype.All penicillin-resistant S.pneumoniae was included in serotypes 6,19 and 23.CONCLUSIONS The antibiotic resistance of S.pneumoniae is serious in Wuhan.Most of them are multi-resistant strains.Except for fluoroquinolones,ceftriaxone and chloramphenicol, most antibiotic agents have lost there activities against S.pneumoniae.The prevalent serotypes,especially of the multi-resistant strains,were 19,23 and 6.Pneumococcal polyvalent vaccine can well cover these serotypes.
9.Activation of protease-activated receptor 2 inhibits apoptosis of lung cancer cells
Shaohong HUANG ; Jun AN ; Yun LI ; Junhang ZHANG ; Jian RONG
Chinese Pharmacological Bulletin 2014;(5):684-687,688
Aim To investigate the activation of prote-ase-activated receptor 2 ( PAR2 ) in regulation of the expression of epidermal growth factor receptor ( EGFR) and apoptosis of lung cancer ( LC) cells. Methods LC cells A549 and its EGFR-silenced counterpart were incubated in the medium added with tryptase. Quanti-tative RT-PCR and Western blotting were used to de-tect the expression of EGFR in A 5 4 9 cells . The apop-tosis and Bax/Bcl-xL of cells were also recorded. Re-sults Treating A549 cells with tryptase in the culture for 48 hrs resulted in a marked increase in the expres-sion of EGFR in A549 cells. Marked decreases in a tryptase dose-dependent manner in apoptotic A549 cells were detected in the presence of tryptase. Expo-sure to tryptase markedly decreased the levels of Bax and increased the levels of Bcl-xL in A549 cells, which were not shown in EGFR-deficient A549 cells. Conclusion Tryptase can increase the expression of EGFR in LC cell line, A549 cells, which protects A549 cells from apoptosis, increases Bcl-xL, and sup-presses Bax in A549 cells.
10.Association between polymorphism of GIuR6 gene and domestic violence in Uygur population on alcoholics in Xinjiang
Cheng ZHANG ; Gaiyu TONG ; Shaohong ZOU ; Zongfeng ZHAO ; Hongbing DONG
Journal of Chinese Physician 2016;18(4):516-519
Objective To investigate the association between glutamate receptor-6 (GIuR6/GRIK2) gene polymorphism and domestic violence in Xinjiang Uygur population on alcoholics.Methods The methods of polymerase chain reaction (PCR) and DNA sequencing technique were conducted to detect rs6922753 and rs2227283 single nucleotide polymorphism of GLUR6 gene in a 104 domestic violence perpetrators on alcoholics and 80 non-domestic violence perpetrators on alcoholics.The association between the polymorphisms and violent behavior was analyzed with SPSS 17.0.Results The frequency of allele (x2 =4.935) and genotype (x2 =7.622) of rs6922753 polymorphisms in the domestic violence group were statistically different from those in the non-domestic violence group (P < 0.05),there was no significant difference between two groups in allele frequencies and genotype in rs2227283 site (P > 0.05).Conclusions GIuR6 gene polymorphism may be associated with domestic violence in Xinjiang Uygur population on alcoholics.