Objective To explore the relationship between serum troponin I (TnI) and troponin T (TnT) and rheumatic diseases with myocardial injury.Methods Solid chromatographic method was used to test serum TnI and TnT in 241 patients with various types of rheumatic diseases consisting of 67 cases of SLE, 31 cases of SS, 18 cases of SSc, 11 cases of PM, 72 cases of RA and 42 cases of AS, which were compared with the normal group, amd the positive rates of which were also compared with CK-MB.Results Among all 241 patients,the positive rates of serum TnI and TnT of each type of rheumatic diseases except AS were higher than that of CK-MB,and the p value in SLE, SSc and RA was significant respectively(P

Objective To investigate the reasonable use of triptorygium wilformed hoof F(TⅡ) and other slow acting antirheumatic drugs(SAARDs).Method Sixty-five patients with rheumatoid arthritis(RA) treated by TⅡ and SAARDs included methotrexate(MTX),sulfasalize (SSZ),azathioprine(AZA) with single or combination among them and followed-up for four years.Results One of SAARDs single therapy was favorable for most RA patients,combined use was needed only in 28 percent cases.Conclusions Based on the heterogeneity of RA, the therapeutic schadule should be altered according to the individual responses.TⅡ effecacy is higher than that of other SAARDs in treatment of patients with RA.

Objective To study the relationship between fragile histidine traid (FHIT), pituitary tumor transforming gene-1 (PTTG-1) in thyroid tumor tissue. Methods The expression of FHIT and PTTG-1 were detected by immunohistocbemistry in 96 eases (56 carcinoma,40 adenoma). Results Compared with thyroid adenoma, the expression of FHIT decreased (P <0.01) ,PTTG-1 increased in thyroid carcinoma(P <0.01). The expression of FHIT is different in thyroid carcinoma in eancerometastasis to non-cancerometastasis (P < 0. 01), prognosis index (≥65) and prognosis index(< 65) (P < 0.01 and P < 0.05) ; There also was statistically significant differences between the expression of PTTG in thyroid carcinoma (P <0.05 and P <0.01). Conclusion FHIT and FTTG-1 may be an important reference significance in the differentiation of benign and malignant thyroid tumor tissue, and may serve as useful prognostic markers.

OBJECTIVETo evaluate the prevalence of primary gout in the Shantou area, China, and to understand its clinical features.

METHODSSamples from three surveys of the Chenghai across ten years were studied. Clinical, laboratory and radiology data of 419 cases of primary gout were collected and analyzed.

RESULTSPrevalence of primary gout in the three surveys were 0.17%, 0.15% and 0.26%, respectively. Among the clinical patients, the ratio of male to female was 21:1; the average age of onset of women was significantly higher than that of men. The number of cases in the last ten years has been increasing. In the first wave of cases, the first metatarsophalangeal joint was involved in 82.1% of all cases; no fourth metatarsophalangeal joint involvement had been observed. Hyperlipemia was the most common accompanying abnormal laboratory test (57.1%). Radiographic bone erosion was found in 49.4% patients, most of them with disease duration more than 5 years.

CONCLUSIONSThe prevalence of primary gout in Shantou area has been increasing in the last ten years. Changes in diet and lifestyle may be responsible for this rapid increase.

Adult ; Aged ; Aged, 80 and over ; China ; epidemiology ; Female ; Gout ; complications ; diagnostic imaging ; epidemiology ; Humans ; Male ; Middle Aged ; Radiography