OBJECTIVETo develop a new injectable biomaterial carrageenan/nano-hydroxyapatite/collagen (nHAC/Carr) for bone surgery and characterize it.

METHODSnHAC/Carr was developed by filling carrageenan with nano-hydroxyapatite/collagen (nHAC) granules.

RESULTSIt was found that nHAC/Carr had similar X-ray diffraction patterns with that of nHAC. Fourier transform infrared spectroscopy showed that carrageenan did not change its structure in nHAC/Carr. The rheological behavior of nHAC/Carr was the same as carrageenan. The scanning electron microscopy and porosity analysis showed that nHAC/Carr had porous structure and its porosity was about 90%.

CONCLUSIONThe biomaterial nHAC/Carr may be used as an injectable bone substitute.

Bone Substitutes ; chemistry ; Carrageenan ; Collagen ; Durapatite ; Injections ; Microscopy, Electron, Scanning ; Nanoparticles ; Porosity ; Surface Properties ; X-Ray Diffraction