1.Diagnosis and prognosis of systemic juvenile rheumatoid arthritis.
Li-hua SHAO ; Min WEI ; Mei DONG
Chinese Journal of Pediatrics 2003;41(1):46-47
Arthritis, Juvenile
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classification
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diagnosis
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therapy
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Child
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Female
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Follow-Up Studies
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Humans
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Male
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Prognosis
2.Different Effects of Triptergium.reglii On T and B cell Function
Dong-Mei ZUO ; Shao-Lun ZHANG ;
Chinese Journal of Immunology 1986;0(04):-
The suppressive effects of T. reglii on mouse cellular and humoral immune responses were studied. Lymphocyte proliferation effect induced with ConA,and PFC and OHS reactions with TD Ag(TNP-SRBC)were effectively suppressed by the drug. But the similar effects on LPS and TI Ag (TNP-SRBC) have not been found. The results shown that target cells of T. reglii effects may be T lymphocytes and the drug may not have a direct effect on B cells. The drug also shown a suppressive effect on IL-2 production by mouse spleen cells. The phenomenon suggests that the suppressive effects of T. reglii on humoral immune response may be indirectly mediated through suppressing helper T cells.
3.Dynamic Change of Cerebral Blood Flow of Newborns with Hypoxic-Ischemic Encephalopathy
shi-qing, SHAO ; dong-mei, NING ; shu-fang, JIN
Journal of Applied Clinical Pediatrics 2004;0(12):-
Objective To observe the dynamic change of cerebral blood flow of newborns with hypoxic-ischemic encephalopathy(HIE).Methods Cerebral blood flow of middle cerebral artery and pulsatility index(PI) on 75 newborns with HIE and 50 normal infants were examined with transcranial doppler sonography at different time points,and the relations between cerebral blood flow and clinic indexes were analyzed.Results The blood velocity of normal infants increased gradually, and PI decreased from 2 to 5 days.The velocities were lower than that of normal infants,and PI was higher at 12th hour and 1st day, but during 2-5 days,the velocities got higher and PI got lower, in which the decrease of velocities correlated positively with Apgar scores and the increase of velocities were negatively correlative to Apgar scores.Compared with the neonates who had poor prognosis retrospectively with those had good prognosis, the velocity changes were found to be more significant.Conclusion The change of cerebral blood flow can show the pathophysiology of HIE and prognosticate the prognosis of neonates with HIE.
4.Photoelastic Stress Analysis of Two Kinds of Rigid Fixed Bridge Design after Hemisection of Mandibular First Molar
Shao-feng ZHANG ; Dong-mei ZHANG ; Tie ZHANG ; Ye YUE
Chinese Journal of Rehabilitation Theory and Practice 2006;12(4):355-356
ObjectiveTo observe the effects of the two kinds of rigid fixed bridge design on the stress of the alveolar bone of mandibular first molar after hemisection.MethodsThe normal mandibular first molars were selected as control group. The two-abutment teeth and three-abutment teeth rigidly fixed bridge designs were selected as trial group. Stress distributions in the remaining sections of the alveolar bone models were evaluated with photoelastic stress analysis method.ResultsThe stress values of two kinds of rigid fixed bridge design were higher than the control group but still below the twice. There was no significantly difference between two-abutment teeth rigidly fixed bridge design and three-abutment teeth rigidly fixed bridge design (P>0.05).ConclusionTwo-abutment teeth rigidly fixed bridge of mandibular first molar should be chosen after hemisection.
5.Development of the Photoelastic Model for the Tooth and Periodontal Tissue of Mandibular First Molar after Hemisection
Dong-mei ZHANG ; Shao-feng ZHANG ; Tie ZHANG
Chinese Journal of Rehabilitation Theory and Practice 2006;12(4):357-358
ObjectiveTo discuss the design and fabrication of the photoelastic model of mandibular first molar after hemisection.MethodsAccording to principles of similarity, different materials were used to manufacture the photoelastic model of mandibular first molar with hemisection, which included teeth, alveolar bone and pericementum.ResultsThe photoelastic modle of mandibular first molar with hemisection was manufactured, which was as similar as noumenon in appearance, parameter and boundary condition.ConclusionThe photoelastic model can be applied in qualitative analysis of the stress distribution in the periodontal supporting tissues of mandibular first molar with hemisection.
6.Study on Xinyueshu spray drying assisted with copovidone and its effect on powder property.
Yan-Rong JIANG ; Zhen-Hai ZHANG ; Dong-Mei DING ; Hong-Mei YAN ; Shao-Ying HU ; Xiao-Bin JIA
China Journal of Chinese Materia Medica 2013;38(23):4067-4070
To study the application characteristics of copovidone (PVP-S630) in Xinyueshu extracts during the spray drying process, and its effect on such pharmaceutical properties as micromeritics and drug release behavior. PVP-S630 was added into Xinyueshu extracts to study on the spray drying, the effect of different dosages of PVP-S630 against the wall sticking effect of the spray drying, as well as the power property of Xinyueshu spray drying power and the dissolution in vitro behavior of the effective component of hyperoside. The results showed that PVP-S630 revealed a significant anti-wall sticking effect, with no notable change in the grain size of the spray drying power, increase in the fluidity, improvement in the moisture absorption and remarkable rise in the dissolution in vitro behavior of hyperoside. It was worth further studying the application of PVP-S630 in spray drying power of traditional Chinese medicine.
Absorption
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Desiccation
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methods
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Drug Compounding
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methods
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Drugs, Chinese Herbal
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chemistry
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Porosity
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Powders
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Pyrrolidines
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chemistry
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Vinyl Compounds
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chemistry
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Wettability
7.ST-11 clonal complex serogroup C Neisseria Meningitidis strain in China.
Mei DONG ; Tie-gang ZHANG ; Meng CHEN ; Fang HUANG ; Zhu-jun SHAO ; Jiang WU
Chinese Medical Journal 2013;126(16):3197-3197
9.Effect of low T_3 syndrome on outcome of acute myocardial infarction
qi, SHAO ; ying, REN ; jun-min, QUAN ; dong-mei, DU ; cui-chun, ZHAO ; meng, WEI
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(12):-
Objective To investigate the prevalence of low T3 syndrome in patients with acute myocardial infarction(AMI) and explore the effect of low T3 syndrome on outcome of AMI.MethodsThree hundred and thirty-eight patients with AMI admitted to cardiac care unit(CCU) underwent examinations of thyroid function and cardial ultrasound,and were further categorized according to thyroid hormone profile.The records of noninvasive bi-level positive airway pressure(BiPAP)ventilation utilization,length of hospital stay,mortality during hospitalization were evaluated,and the related factors were analysed.ResultsOne hundred and thirty-nine of the 338 patients(41.12%) with AMI complicated with low T3 syndrome.Free triiodothyronine(FT3) was the independent influential factor for length of hospital stay.Low FT3 was significantly correlated with noninvasive BiPAP ventilation utilization and mortality during hospitalization.The average time of follow-up was(21.4?8.1) months.It was revealed by multivariate Cox regression analysis that FT3 was the chief predictor for cumulative death(risk ratio,4.25;95% confidential interval,2.30-7.87),followed by age and left ventricular ejection fraction.ConclusionThe recognition of AMI complicated with low T3 syndrome plays an important role in predicting the disease severity and outcome.
10.Effects of Fluid Resuscitation on Cerebral Protection in A Rat Model of Traumatic Head Injury Complicated with Hemorrhagic Shock
Hong-xun MEI ; Shao-dong ZHANG ; En-zhen WANG ; Hong WANG
Chinese Journal of Rehabilitation Theory and Practice 2006;12(5):396-398
ObjectiveTo compare the effects of normal saline (NS), 10% hydroxyethyl starch (HES) and hypertonic-hyperoncotic solution (HHS,7.5% NaCl/10% HES) on regional cerebral blood flow (rCBF), brain edema and blood-brain barrier (BBB) in a rat model of traumatic head injury (THI) complicate with hemorrhagic shock. Methods60 SD rats were randomized into 5 groups: sham group (n=12), model group (n=12), NS group (n=12), HES group (n=12) and HHS group (n=12). rCBF and mean arterial pressure (MAP) were determined before and after THI, hemorrhagic shock and resuscitation. Cerebral water content and Evans Blue (EB) content were assessed 3 h after resuscitation.ResultsMAP and rCBF were restored to baseline values immediately after resuscitation in all resuscitated group and began to decrease 15 min, 30 min or 45 min later, respectively(P<0.05). 3 h after resuscitation, the brain water content was higher in NS group than those in sham or HHS group(P<0.05). EB contents of injured hemispheres were higher in model and NS group than those in HES or HHS group(P<0.05). ConclusionSmall-volume resuscitation with HHS can restore MAP and rCBF, decrease brain edema and improve BBB in a rat model of THI complicate with hemorrhagic shock.