2.Results of preservative free sodium hyaluronate and basic fibroblast growth factor eye drops in the treatment of dry eyes after ophthalmic surgery
Meng, WANG ; Gui-Qiu, ZHAO ; Shao-Xin, PAN ; Li-Li, ZHANG ; Kui-Xiang, LIU
International Eye Science 2008;8(10):1972-1974
AIM: To evaluate the results of preservative free sodium hyaluronate and basic fibroblast growth factor(bFGF) eye drops in the treatment of dry eyes after eye operation.·METHODS: One hundred and thirty two patients of dryeyes underwent 149 different eye surgeries. The Schirmer test Ⅰ and tear break up time (BUT) were performed prior to surgery and post operatively after 2 weeks and after 4 weeks when the patients were using Oflaxacine, Tobramycin-dexamethasone eye drops. In addition, preservative free sodium hyaluronate and bFGF eye drops were given post operatively. The antibiotic-cortisone eye drops were stopped after the requirted period depending on the type of eye surgery done, and preservative free sodium hyaluronate and bFGF eye drops were stopped after 4 weeks.Then, after 5 weeks Schirmer test Ⅰ and BUT were done.·RESULTS: The Schirmer test Ⅰ and BUT results prior to surgery and after eye surgery showed a statistically significant improvement of the dry eye condition.·CONCLUSION: Usage of preservative free sodium hysluronate and bFGF eye drops help definitely in the management of dry eye after ophthalmic surgery.
3.Relationship of body mass index, fat free mass index, and fat mass index with inspiratory capacity in adults with normal lung function.
Kui FENG ; Li CHEN ; Shao-mei HAN ; Guang-jin ZHU
Acta Academiae Medicinae Sinicae 2010;32(1):85-89
OBJECTIVETo study the relationship of inspiratory capacity (IC) with body mass index (BMI), fat free mass index (FFMI), and fat mass index (FMI) in adults with normal lung function.
METHODSBased on a survey on the Chinese physiological constants conducted in Heilongjiang during 2008, we obtained the data of 2,050 adults (921 men and 1,129 women aged 19-81 years) with normal lung function and grouped them according to the standard of classification of body weight recommended by Working Group on Obesity of China. Statistical analysis was performed using Pearson correlation analysis, one-way analysis of variance,and multi-factor regression analysis.
RESULTSAfter the influences of age and gender were adjusted, IC was positively correlated with BMI, FFMI, and FMI in adults aged 19-81 years (all P= 0.000) (the correlation coefficients were 0.320, 0.303, and 0.204, respectively). The means of IC, FFMI, and FMI in obesity group were significantly higher than those in overweight group normal weight group, and underweight group, were significantly higher in overweight group than in normal weight group and underweight group, were significantly higher in normal weight group than in underweight group (all P = 0.000). Multiple stepwise regression analysis showed that factors including age, gender, height, FFMI, and FMI influenced IC, and while height, FFMI, and FMI were positively correlated with IC, gender and age were negatively correlated with IC.
CONCLUSIONSBMI, FFMI, and FMI are positively correlated with IC in adults with normal lung function. The elevation of IC derived from BMI may attribute to FFMI and FMI, and FFMI has a higher influence on IC than FMI does.
Adult ; Aged ; Aged, 80 and over ; Analysis of Variance ; Body Composition ; physiology ; Body Mass Index ; China ; Female ; Humans ; Inspiratory Capacity ; Male ; Middle Aged ; Regression Analysis ; Young Adult
4.Nursing of 28 patients with portal hypertension for embolization of esophageal-gastric fundus varices
Ling-Yun LIU ; Shao-Zhu WU ; Xiao-Hui LI ; De-Kui ZHANG ; Miao-Xia CHEN
Chinese Journal of Modern Nursing 2009;15(14):1333-1335
Objective To explore the nursing of embolization with tissue adhesive NBCA (n-butyl-2-cyano-acrylate) for patients with esophageal-gastric fundus varices in portal hypertension. Methods The clinical data and nursing of 28 cases with NBCA embolization for esophageal-gastric fundus varices in portal hypertension were retrospectively analyzed during and after the intervention. Results 27 cases were embolized successfully with obtaining hemostatic effects, and the other one case failed. Among the 26 successful cases, there were 4 cases with pulmonary thromboembolism, 2 cases with one-off cough, 20 cases with vomiting and mild abdominal pain, and no case with puncture and intraperitoneal hemorrhage. Conclusions It is important for nurses to give patients pertinent psychological nursing before operation, to closely observe the disease situation during embolization and to careftdly observe and nurse after operation to increase the success rate of operation and reduce the complications.
5.Clinical observation of selective posterior rhizotomy for improving spasticity and gross movement in patients with cerebral palsy.
Jie XU ; Lin XU ; Jie ZENG ; Xing-Kui YANG ; Zhao-Hui LI ; Gao-Kai SHAO ; Xiao-Ye LI ; Bo-Wen DENG ; Xiao-Hong MU
China Journal of Orthopaedics and Traumatology 2019;32(9):815-819
OBJECTIVE:
To explore the effect of selective lumbosacral posterior rhizotomy(SPR) on lower limb spasticity and gross motor function in patients with cerebral palsy.
METHODS:
From January 2018 to October 2018, 47 patients with cerebral palsy were treated with rehabilitation alone and SPR combined with rehabilitation. According to whether SPR was performed, the patients were divided into group A and group B. Group A was treated with rehabilitation combined with SPR at lumbosacral level, and group B was treated with rehabilitation alone. There were 23 cases in group A, including 15 males and 8 females, with an average age of (7.30±3.25) years old; 24 cases in group B, 13 males and 11 females, with an average age of (7.00±3.09) years old. Forty-seven patients were assessed with modified Ashworth(MAS) and Gross Motor Function Scale(GMFM-88 items) before and after treatment. The changes of MAS and GMFM-88 scores before and after treatment were compared to evaluate the degree of spasm and the improvement of gross motor function in the two groups.
RESULTS:
All 47 patients were followed up. At 6 months after treatment, the MAS classification of the two groups was significantly improved(<0.05), and the improvement of group A was more obvious than that of group B(<0.05). Six months after treatment, the D, E and total scores of GMFM-88 between two groups were significantly improved compared with those before operation(<0.05). The improvement of D and total scores in group A was more obvious than that in group B. There was no significant difference in the improvement of area E between two groups.
CONCLUSIONS
Selective posterior rhizotomy combined with rehabilitation can significantly improve the spastic state and gross motor function of lower limbs in children with cerebral palsy, and can effectively promote the reconstruction and recovery of motor function of lower limbs in children with cerebral palsy.
Cerebral Palsy
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surgery
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Child
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Child, Preschool
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Female
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Humans
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Lower Extremity
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Male
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Movement
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Muscle Spasticity
;
Rhizotomy
6.Preliminary study of gemstone spectral imaging in measuring thyroid iodine content
Wei-guang, SHAO ; Dian-mei, LIU ; Mao-yi, ZHOU ; Li-xin, LI ; Jin-gang, LIU ; Xing-sheng, ZHAO ; Dong-wen, ZHANG ; Kui-tao, YUE ; Shuai NG ZHA ; Hui-zhi, CAO
Chinese Journal of Endemiology 2012;31(2):212-215
ObjectiveTo measure the iodine content of normal thyroid and the sternocleidomastoid muscle with gemstone spectral imaging (GSI),in order to offer diagnostic reference for iodine excess or iodine deficiency disorders.MethodsA total of 226 cases of patients with suspected neck or cervical disease underwent GSI of the neck,the thyroid and the sternocleidomastoid muscle.One hundred and nineteen cases were male and 107 female,aged 18 to 77 years,average age(46 ± 17) years.Data were transmitted to AW 4.4 workstation and processed using GSI Viewer software to obtain the best contrast-to-noise ratio(CNR) of thyroid to sternocleidomastoid muscle and corresponding singe-energy images.Iodine content of left and right thyroid lobes and both sides of sternocleidomastoid muscle as well as iodine content ratio of thyroid to sternocleidomastoid muscle were calculated in the iodine-based images.ResultsTotal iodine content of the left and the right lobes of the thyroid was (1.5233 ±0.4318)mg/cm3,of the left lobe was (1.5230 ± 0.4271 )mg/cm3,of the right lobe was (1.5236 ± 0.4365 )mg/cm3,there was no significant difference statistically between the two(t =0.0084,P > 0.05).The iodine content of the male was (1.6395 ± 0.4105)mg/cm3,and of the female was (1.4238 ± 0.3832)mg/cm3,there was statistically a significant difference between the two(t =3.4743,P < 0.01 ).Iodine content ratio of thyroid to sternocleidomastoid muscle was 96.6271 ± 33.2442,the ratio in male was 94.6250 ± 37.3621 and in female was 98.0000 ± 29.0737,there was no statistical difference between the two(t =0.3817,P > 0.05).The iodine content of thyroid decreased gradually with age,the difference between groups was statistically significant(F =9.66,P < 0.01 ).The iodine content in < 40 age group[(1.7256 ± 0.4631)mg/cm3] was higher than that in 40 - 60 age group[(1.4517 ±0.3643)mg/cm3] and > 60 age group [(1.4368 ± 0.3465)mg/cm3; q =5.6195,5.4158,all P < 0.01).Conclusions It is easy to calculate thyroid iodine content with gemstone spectral imaging,which can reflect the iodine level of our body,and is helpful for the diagnosis of iodine excess or iodine deficiency disorders.
7.Spirometric Standards for Healthy Children and Adolescents of Korean Chinese in Northeast China.
Kui FENG ; Li CHEN ; Shao Mei HAN ; Guang Jin ZHU
Journal of Korean Medical Science 2011;26(11):1469-1473
In China there are 1,923,842 Korean Chinese, who live mostly (92.27%) in the country's three northeast provinces. In spite of this sizeable number, no spirometric data are available at present on them. The present study investigated normal spirometric reference values for the Korean Chinese children and adolescents. Spirometry was performed in 443 healthy Korean Chinese children and adolescents aged 8-18 yr with measurements of forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), peak expiratory flow (PEF) and maximum mid-expiratory flow (MMEF). Reference equations for FEV1, FVC, PEF and MMEF were derived by using multiple regression analysis. All of the measured spirometric parameters correlated positively with height and age significantly (P < 0.001). The predicted values of FVC and FEV1 were higher than values obtained by using Caucasian and other Asian equations (P < 0.001). A set of spirometric reference equations has been derived using a relatively large, healthy, non-smoking young Korean Chinese population with a wide range of ages and heights, the results of which differ from those gained from several other reference equations. These reference equations should be used for evaluation of lung function in this population.
Adolescent
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Child
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China
;
Female
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*Forced Expiratory Volume
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Humans
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Lung/*physiology
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Male
;
Maximal Expiratory Flow Rate
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Peak Expiratory Flow Rate
;
Reference Values
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Republic of Korea/ethnology
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Spirometry/*standards
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*Vital Capacity
8.Relation between fat mass, fat free mass and ventilatory function in children and adolescents.
Dan-Yang WANG ; Kui FENG ; Li CHEN ; Shu-Yu ZU ; Shao-Mei HAN ; Guang-Jin ZHU
Acta Physiologica Sinica 2010;62(5):455-464
The aim of the present study was to evaluate the relation between fat mass (FM), fat free mass (FFM) and ventilatory function in children and adolescents. 1 174 healthy children and adolescents (583 males and 591 females) aged 10-18 years were selected from Heilongjiang Province through random sampling by means of questionnaire and physical examination, and measured for height, weight, waist to hip ratio (WHR), FM, FFM and ventilatory function. The data were analyzed by means of independent-samples t test, Pearson correlation analysis and multi-factors regression analysis. Regardless of sex, an independent positive correlation was found (P<0.001) between age and FFM index (FFMI). FM index (FMI) correlated negatively with age in males (P<0.001), but positively with age in females (P<0.001). Regardless of sex, FFMI correlated positively with forced vital capacity (FVC), forced expiratory volume in one second (FEV1), peak expiratory flow (PEF), forced expiratory flow at 25% of forced vital capacity (FEF25%), FEF50%, and maximal mid-expiratory flow (MMEF) (P<0.05), while negatively with FEV1/FVC (P<0.01). FFMI was correlated positively with FEF75% in males (P<0.05), but not correlated in females. In males, FMI correlated negatively with FEV1, FEV1/FVC, PEF, FEF25%, FEF50%, FEF75% and MMEF (P<0.05), but not correlated with FVC. No correlation was found between the ventilatory function indices and FMI in females. Except FEV1/FVC and FEF75% in males, the effect of FFMI in predicting ventilatory function was higher than FMI regardless of sex. Moreover, the predicting effect of FFMI was higher in males than that in females. Growth spurt of lung function occurred in the ages of 12-15 years in males, while in the ages of 12, 13 and 18 years in females. During the period of growth spurt of lung function, regardless of sex, the effect of FFMI in predicting the lung function was higher than that of age. In conclusion, regardless of sex, FFMI correlates positively with ventilatory function, as a reflection of muscle mass. The effect of FFM in predicting ventilatory function is higher in males than that in females. FM correlates negatively with ventilatory function in males, but not in females. The rapid growth of height and FFM are possibly the main reasons for growth spurt of lung function.
Adipose Tissue
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anatomy & histology
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physiology
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Adolescent
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Body Composition
;
physiology
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Body Mass Index
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Child
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Female
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Humans
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Male
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Pulmonary Ventilation
;
physiology
;
Respiratory Function Tests
9.Fat mass and fat free mass on ventilatory function in adults.
Kui FENG ; Li CHEN ; Shu-Yu ZU ; Shao-Mei HAN ; Guang-Jin ZHU
Acta Physiologica Sinica 2010;62(2):122-128
This study is designed to probe for the effects of fat mass (FM) and fat free mass (FFM) on ventilatory function in adults. 1 307 healthy adults (372 males and 935 females) were selected from some localities of Heilongjiang province through random sampling by means of questionnaire and physical examination and measured for height, weight, waist to hip ratio (WHR), FM, FFM and ventilatory function. The data were analyzed by means of Pearson correlation analysis, independent-samples t test and multi-factors regression analysis. Regardless of sex, an independent positive correlation was found (P<0.001) between age and fat mass index (FMI). Regardless of sex, fat free mass index (FFMI) was found to be positively associated with forced vital capacity (FVC), forced expiratory volume in one second (FEV1), peak expiratory flow (PEF) and forced expiratory flow at 25% of forced vital capacity (FEF25%) (P<0.01), and FMI was significantly and negatively related to FVC, FEV1, FEF75% (P<0.05). In males FMI was significantly and negatively related to maximal mid-expiratory flow (MMEF) (P<0.05). Regardless of sex, the effect of FFMI on FVC was higher than that of FMI. For the males, the effect of FFMI on FVC was smaller than that of FMI, while the opposite was found in the females. Regardless of sex, FEF75% tended to decrease with increasing FMI, while FFMI was found to have no effects on FEF75%. MMEF tended to decrease with increasing FMI in the males, but no marked change was found in the females. The above results suggest that FM and FFM are independent factors influencing ventilatory function in adults. FM is negatively correlated with ventilatory function, but as a reflection of muscle mass, FFM is positively correlated with ventilatory function in adults. There is quantitative difference between the effects of FFM and FM on ventilatory function.
Adipose Tissue
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Adult
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Aged
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Aged, 80 and over
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Body Composition
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physiology
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Body Height
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Body Weight
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physiology
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China
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Female
;
Humans
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Male
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Middle Aged
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Pulmonary Ventilation
;
physiology
;
Surveys and Questionnaires
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Waist-Hip Ratio
;
Young Adult
10.Effect of different-intensity SEMFs on bone mineral density and histomorphometry in SD rats.
Yu-hai GAO ; Kui CHENG ; Bao-Feng GE ; Ping ZHEN ; Jian ZHOU ; Xiao-Ni MA ; Shao-Feng LI ; Ke-Ming CHEN
China Journal of Orthopaedics and Traumatology 2014;27(11):933-937
OBJECTIVETo investigate the effects of different-intensity sinusoidal electromagnetic fields (SEMFs) on bone mineral density (BMD) and histomorphometry in SD rats.
METHODSThirty female SD rats were randomly divided into three groups: group A (a control group), group B (0.1 mT group) and group C (0.6 mT group). The rats in group B and C were exposed to 50 Hz SEMFs 3 hours each day. However,the magnetic intensity was different between group B and group C:0.1 mT for group B and 0.6 mT for group C. After 8 weeks, all the animals were killed. Changes of BMD and histomorphometric properties were observed.
RESULTSCompared with group A, the BMD of whole body, femur and vertebrae of rats in group B increased significantly; the area percentage, number and width of bone trabeculae in vertebrae and femur of rats in group B were larger than those of group A; but the resolution of bone trabeculae of rats in group B was lower than that of group A. The trabecular number in group C rats were significantly decreased, compared with that in group A rats. The outcome of double fluorescence labeling in group B was found to be significantly different with that in group A. But the difference between rats in group A and C was not significant.
CONCLUSIONThis study demonstrates that 50 Hz 0.1 mT SEMFs can increase BMD, improve bone tissue microstructure and, promote bone formation.
Animals ; Bone Density ; radiation effects ; Electromagnetic Fields ; Female ; Lumbar Vertebrae ; pathology ; radiation effects ; Osteogenesis ; radiation effects ; Rats ; Rats, Sprague-Dawley ; Tibia ; pathology ; radiation effects