Adult ; Aged ; Aged, 80 and over ; Anthracosis ; complications ; Diagnostic Imaging ; Humans ; Lung Neoplasms ; epidemiology ; etiology ; Middle Aged ; Retrospective Studies

AIM: To evaluate the results of preservative free sodium hyaluronate and basic fibroblast growth factor(bFGF) eye drops in the treatment of dry eyes after eye operation.·METHODS: One hundred and thirty two patients of dryeyes underwent 149 different eye surgeries. The Schirmer test Ⅰ and tear break up time (BUT) were performed prior to surgery and post operatively after 2 weeks and after 4 weeks when the patients were using Oflaxacine, Tobramycin-dexamethasone eye drops. In addition, preservative free sodium hyaluronate and bFGF eye drops were given post operatively. The antibiotic-cortisone eye drops were stopped after the requirted period depending on the type of eye surgery done, and preservative free sodium hyaluronate and bFGF eye drops were stopped after 4 weeks.Then, after 5 weeks Schirmer test Ⅰ and BUT were done.·RESULTS: The Schirmer test Ⅰ and BUT results prior to surgery and after eye surgery showed a statistically significant improvement of the dry eye condition.·CONCLUSION: Usage of preservative free sodium hysluronate and bFGF eye drops help definitely in the management of dry eye after ophthalmic surgery.

OBJECTIVETo study the relationship of inspiratory capacity (IC) with body mass index (BMI), fat free mass index (FFMI), and fat mass index (FMI) in adults with normal lung function.

METHODSBased on a survey on the Chinese physiological constants conducted in Heilongjiang during 2008, we obtained the data of 2,050 adults (921 men and 1,129 women aged 19-81 years) with normal lung function and grouped them according to the standard of classification of body weight recommended by Working Group on Obesity of China. Statistical analysis was performed using Pearson correlation analysis, one-way analysis of variance,and multi-factor regression analysis.

RESULTSAfter the influences of age and gender were adjusted, IC was positively correlated with BMI, FFMI, and FMI in adults aged 19-81 years (all P= 0.000) (the correlation coefficients were 0.320, 0.303, and 0.204, respectively). The means of IC, FFMI, and FMI in obesity group were significantly higher than those in overweight group normal weight group, and underweight group, were significantly higher in overweight group than in normal weight group and underweight group, were significantly higher in normal weight group than in underweight group (all P = 0.000). Multiple stepwise regression analysis showed that factors including age, gender, height, FFMI, and FMI influenced IC, and while height, FFMI, and FMI were positively correlated with IC, gender and age were negatively correlated with IC.

CONCLUSIONSBMI, FFMI, and FMI are positively correlated with IC in adults with normal lung function. The elevation of IC derived from BMI may attribute to FFMI and FMI, and FFMI has a higher influence on IC than FMI does.

Adult ; Aged ; Aged, 80 and over ; Analysis of Variance ; Body Composition ; physiology ; Body Mass Index ; China ; Female ; Humans ; Inspiratory Capacity ; Male ; Middle Aged ; Regression Analysis ; Young Adult

Objective To explore the nursing of embolization with tissue adhesive NBCA (n-butyl-2-cyano-acrylate) for patients with esophageal-gastric fundus varices in portal hypertension. Methods The clinical data and nursing of 28 cases with NBCA embolization for esophageal-gastric fundus varices in portal hypertension were retrospectively analyzed during and after the intervention. Results 27 cases were embolized successfully with obtaining hemostatic effects, and the other one case failed. Among the 26 successful cases, there were 4 cases with pulmonary thromboembolism, 2 cases with one-off cough, 20 cases with vomiting and mild abdominal pain, and no case with puncture and intraperitoneal hemorrhage. Conclusions It is important for nurses to give patients pertinent psychological nursing before operation, to closely observe the disease situation during embolization and to careftdly observe and nurse after operation to increase the success rate of operation and reduce the complications.

ObjectiveTo measure the iodine content of normal thyroid and the sternocleidomastoid muscle with gemstone spectral imaging (GSI),in order to offer diagnostic reference for iodine excess or iodine deficiency disorders.MethodsA total of 226 cases of patients with suspected neck or cervical disease underwent GSI of the neck,the thyroid and the sternocleidomastoid muscle.One hundred and nineteen cases were male and 107 female,aged 18 to 77 years,average age(46 ± 17) years.Data were transmitted to AW 4.4 workstation and processed using GSI Viewer software to obtain the best contrast-to-noise ratio(CNR) of thyroid to sternocleidomastoid muscle and corresponding singe-energy images.Iodine content of left and right thyroid lobes and both sides of sternocleidomastoid muscle as well as iodine content ratio of thyroid to sternocleidomastoid muscle were calculated in the iodine-based images.ResultsTotal iodine content of the left and the right lobes of the thyroid was (1.5233 ±0.4318)mg/cm3,of the left lobe was (1.5230 ± 0.4271 )mg/cm3,of the right lobe was (1.5236 ± 0.4365 )mg/cm3,there was no significant difference statistically between the two(t =0.0084,P ＞ 0.05).The iodine content of the male was (1.6395 ± 0.4105)mg/cm3,and of the female was (1.4238 ± 0.3832)mg/cm3,there was statistically a significant difference between the two(t =3.4743,P ＜ 0.01 ).Iodine content ratio of thyroid to sternocleidomastoid muscle was 96.6271 ± 33.2442,the ratio in male was 94.6250 ± 37.3621 and in female was 98.0000 ± 29.0737,there was no statistical difference between the two(t =0.3817,P ＞ 0.05).The iodine content of thyroid decreased gradually with age,the difference between groups was statistically significant(F =9.66,P ＜ 0.01 ).The iodine content in ＜ 40 age group[(1.7256 ± 0.4631)mg/cm3] was higher than that in 40 - 60 age group[(1.4517 ±0.3643)mg/cm3] and ＞ 60 age group [(1.4368 ± 0.3465)mg/cm3; q =5.6195,5.4158,all P ＜ 0.01).Conclusions It is easy to calculate thyroid iodine content with gemstone spectral imaging,which can reflect the iodine level of our body,and is helpful for the diagnosis of iodine excess or iodine deficiency disorders.

OBJECTIVE: To explore the effect of selective lumbosacral posterior rhizotomy(SPR) on lower limb spasticity and gross motor function in patients with cerebral palsy. METHODS: From January 2018 to October 2018, 47 patients with cerebral palsy were treated with rehabilitation alone and SPR combined with rehabilitation. According to whether SPR was performed, the patients were divided into group A and group B. Group A was treated with rehabilitation combined with SPR at lumbosacral level, and group B was treated with rehabilitation alone. There were 23 cases in group A, including 15 males and 8 females, with an average age of (7.30±3.25) years old; 24 cases in group B, 13 males and 11 females, with an average age of (7.00±3.09) years old. Forty-seven patients were assessed with modified Ashworth(MAS) and Gross Motor Function Scale(GMFM-88 items) before and after treatment. The changes of MAS and GMFM-88 scores before and after treatment were compared to evaluate the degree of spasm and the improvement of gross motor function in the two groups. RESULTS: All 47 patients were followed up. At 6 months after treatment, the MAS classification of the two groups was significantly improved(<0.05), and the improvement of group A was more obvious than that of group B(<0.05). Six months after treatment, the D, E and total scores of GMFM-88 between two groups were significantly improved compared with those before operation(<0.05). The improvement of D and total scores in group A was more obvious than that in group B. There was no significant difference in the improvement of area E between two groups. CONCLUSIONS Selective posterior rhizotomy combined with rehabilitation can significantly improve the spastic state and gross motor function of lower limbs in children with cerebral palsy, and can effectively promote the reconstruction and recovery of motor function of lower limbs in children with cerebral palsy.
Cerebral Palsy ; surgery ; Child ; Child, Preschool ; Female ; Humans ; Lower Extremity ; Male ; Movement ; Muscle Spasticity ; Rhizotomy

In China there are 1,923,842 Korean Chinese, who live mostly (92.27%) in the country's three northeast provinces. In spite of this sizeable number, no spirometric data are available at present on them. The present study investigated normal spirometric reference values for the Korean Chinese children and adolescents. Spirometry was performed in 443 healthy Korean Chinese children and adolescents aged 8-18 yr with measurements of forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), peak expiratory flow (PEF) and maximum mid-expiratory flow (MMEF). Reference equations for FEV1, FVC, PEF and MMEF were derived by using multiple regression analysis. All of the measured spirometric parameters correlated positively with height and age significantly (P < 0.001). The predicted values of FVC and FEV1 were higher than values obtained by using Caucasian and other Asian equations (P < 0.001). A set of spirometric reference equations has been derived using a relatively large, healthy, non-smoking young Korean Chinese population with a wide range of ages and heights, the results of which differ from those gained from several other reference equations. These reference equations should be used for evaluation of lung function in this population.
Adolescent ; Child ; China ; Female ; *Forced Expiratory Volume ; Humans ; Lung/*physiology ; Male ; Maximal Expiratory Flow Rate ; Peak Expiratory Flow Rate ; Reference Values ; Republic of Korea/ethnology ; Spirometry/*standards ; *Vital Capacity

OBJECTIVETo investigate the clinicopathological characteristics and prognostic factors in patients with intra-abdomen extragastrointestinal stromal tumors (EGISTs).

METHODSThe data of 47 patients of mesenchymal neoplasms that arose from the abdominal cavity and retroperitoneum, collected from July 1987 to June 2003 in our hospital with complete clinical and pathological data, were investigated retrospectively. EGISTs were diagnosed by reviewing the tumor slides stained with hematoxylin and eosin (H&E). Immunohistochemistry staining were performed on CD117, CD34, smooth muscle actin, Desmin and S-100 proteins. The relations of various clinicopathologic characteristics and outcomes were examined.

RESULTSAmong the 47 cases, 30 tumors were confirmed to be EGISTs. Twelve cases arose from the mesentery, six from small omentum, eight from retroperitoneum and four from the abdominal cavity. The size of tumors ranged from 4 to 30 cm (median 12.5 cm) in diameter and the tumor cell components mainly included spindle cells (23 cases), epithelioid cells (4 cases), and mixed cells (3 cases). The follow-up rate was 90% and the median follow up time was 44 months. The patient survival rates at 1, 5 and 10 years were 79.7%, 59.5% and 45.4% respectively. Univariate analysis showed that tumor size >10 cm, tumor necrosis, mitoses > or =5/50HPF, obvious nuclear atypia, moderate and poor differentiated tumor cells were predictors of poor prognosis.

CONCLUSIONSEGISTs have specific clinical behaviors. The parameters used for predicting GISTs prognosis are not completely applicable for EGISTs. Tumor necrosis, obvious nuclear atypia and mitoses > or =5/50HPF help to predict aggressive behaviors in EGISTs.

Adult ; Female ; Humans ; Immunohistochemistry ; Middle Aged ; Peritoneal Neoplasms ; pathology ; Retroperitoneal Neoplasms ; pathology ; Retrospective Studies

OBJECTIVETo identify the clinical pathological characteristics and prognostic factors in patients with gastrointestinal stromal tumors of the stomach.

METHODSThe data of 98 patients of gastric stromal tumors, leiomyomas, leiomyosarcomas, leiomyoblastomas, schwannomas and neurofibromas, collected from Mar. 1983 to Dec. 2001 in our hospital with complete clinical and pathological data, were investigated retrospectively. Gastric stromal tumors were diagnosed by reviewing the tumor slides stained with hematoxylin and eosin (H&E). Two histomorphologically representative areas of each tumor slides were identified and arrayed on a tissue microarray. Immunohistochemistry staining were performed using antibodies to c-kit (CD117), CD34, smooth muscle actin (SMA), Desmin and S-100 proteins. The relations of various clinicopathologic characteristics and outcomes were tested by univariate analysis and multivariate analysis.

RESULTSNinety-one patients were clearly identified as gastric stromal tumors from the 98 patients, who were diagnosed as gastric stromal tumor, leiomyoma, leiomyosarcoma, leiomyoblastoma schwannoma and neurofibroma (92.9%). The follow-up rate was 91% and the median follow up time was 54 months. The patient survival rates at 1, 5 and 10 years were 88.8%, 79.6% and 63.7% respectively. Univariate analysis showed that tumor size, mitotic count, tumor necrosis, nuclear pleomorphism, cell type, cell density, surgical procedure, mucosal invasion, age and lable index of Ki-67 were associated with prognosis (P<0.05). Multivariate analysis showed that tumor size, mitotic count, mucosal invasion and tumor necrosis were predictors of prognosis (P<0.05).

CONCLUSIONTumor size of >10 cm, mitotic count of >10 mitoses per 50 high power fields, necrosis and mucosal invasion are often associated with an aggressive clinical course in gastric stromal tumors.

Adult ; Aged ; Female ; Gastrointestinal Stromal Tumors ; diagnosis ; pathology ; Humans ; Immunohistochemistry ; Middle Aged ; Prognosis ; Retrospective Studies ; Survival Rate

The aim of this study is to develop backpropagation neural networks (BPNN) for better prediction of ventilatory function in children and adolescents. Nine hundred and ninety-nine healthy children and adolescents (500 males and 499 females) aged 10-18 years, all of the Han Nationality, were selected from Inner Mongolia Autonomous Region, and their heights, weights, and ventilatory functions were measured respectively by means of physical examination and spirometric test. Using the approaches of BPNN and stepwise multiple regression, the prediction models and equations for forced vital capacity (FVC), forced expiratory volume in one second (FEV1), peak expiratory flow (PEF), forced expiratory flow at 25% of forced vital capacity (FEF25%), forced expiratory flow at 50% of forced vital capacity (FEF50%), maximal mid-expiratory flow (MMEF) and forced expiratory flow at 75% of forced vital capacity (FEF75%) were established. Through analyzing mean squared difference (MSD) and correlation coefficient (R) of the ventilatory function indexes, the present study compared the results of BPNN, linear regression equation based on this work (LR's equation), prediction equations based on the studies of Ip et al. (Ip's equation) and Zapletal et al. (Zapletal's equation). The results showed, regardless of sex, the BPNN prediction models appeared to have smaller MSD and higher R values, compared with those from the other prediction equations; and the LR's equation also had smaller MSD and higher R values compared with those from Ip's and Zapletal's equations. The coefficients of variance (CV) for FEF50%, MMEF and FEF75% were higher than those of the other ventilatory function parameters, and their increasing percentages of R values (ΔR, relative to R values by LR's equation) derived by BPNN were correspondingly higher than those of the other indexes. In sum, BPNN approach for ventilatory function prediction outperforms the traditional regression methods. When CV of a certain ventilatory function parameter is higher, the superiority of BPNN would be more significant compared with traditional regression methods.
Adolescent ; Child ; China ; Female ; Forced Expiratory Volume ; physiology ; Forecasting ; Humans ; Lung ; physiology ; Male ; Neural Networks (Computer) ; Peak Expiratory Flow Rate ; physiology ; Pulmonary Ventilation ; physiology ; Reference Values ; Sampling Studies ; Vital Capacity ; physiology