1.Comparative study of coronary artery lesions in myocardial infarction patients with or without acute ST segment elevation
Weiya YU ; Tingshu YANG ; Fang SHAO
Journal of Third Military Medical University 2003;0(20):-
Objective To investigate the differences of coronary artery lesion between myocardial infarction patients with or without ST segment elevation. Methods This study included 126 confirmed myocardial infarction patients with acute ST segment elevation (STEMI) and 96 confirmed myocardial infarction patients with acute non-ST segment elevation (NSTEMI). All patients received coronary angiography and the results were compared between two groups. Results More myocardial patients were with single vessel disease in STEMI group as compared with NSTEMI group (44% vs 14%, P
2.Experimental Teaching Reformation in Nuclear Medicine
Fang-Xin LIU ; Xiao-Yu LI ; Shao-Lin LI ;
Chinese Journal of Medical Education Research 2006;0(07):-
Considering the present condition of nuclear medicine experiment teaching and management model,this paper proposes some reform measures:reforming teaching model,adjusting teaching content,enhancing lab management.
4.Research on the diversified clinical teaching evaluation system in nursing obstetrics and gynecology
Mengyan XU ; Xiaoyan YU ; Xinfen XU ; Fang SHAO ; Xiangrong XU
Chinese Journal of Medical Education Research 2003;0(03):-
We establish the new student-centered teaching mode and reform the evaluation system in clinical teaching of nursing obstetrics and gynecology. We have got more satisfied teaching quality.
6.Detection of hydrogen phosphide in blood and lung tissue of patient with acute hydrogen phosphide poisoning.
Shao-feng FANG ; Li-hui GUI ; Yu-xin YANG ; Da-qing HAO ; Jing-zhuan XI
Chinese Journal of Industrial Hygiene and Occupational Diseases 2005;23(2):82-82
Acute Disease
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Adult
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Chromatography, Gas
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Female
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Humans
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Lung
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chemistry
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Phosphines
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analysis
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blood
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poisoning
7.99mTc-TRODAT-1 SPECT imaging of dopamine transporter in early diagnosis of Parkinsons disease.
Weifeng LUO ; Shiyao BAO ; Jinchang WU ; Yu FU ; Chunfeng LIU ; Guofu SHAO ; Ping FANG
Chinese Journal of Nervous and Mental Diseases 2001;27(2):106-108
Objective To evaluate the value of 99m Tc-TRODAT-1 SPECT DAT imaging in the early diagnosing of Parkinsons disease (PD).Methods Eleven patients (9 PD and 2 possible PD) and eighteen healthy subjects matched by sex and age were studied with 99m Tc-TRODAT-1 SPECT DAT imaging. Striatum specific uptake of 99mTc-TRODAT-1 was calculated according to the ratio of DAT uptake in striatum (ST) and cerebellum (CB). Results In the hemi-Parkinsons disease group, the DAT specific uptake of 99mTc-TRODAT-1 was significantly lower (P<0.01) in contralateral than in ipsilateral striatum to the clinically symptomatic side. There was significant decrease (p<0.01) of striatum DAT uptake in patients with hemi-PD compared to the controls.Conclusions 99mTc-TRODAT-1 SPECT DAT imaging may help to confirm the diagnosis of PD at the early stage.
8.An experimental study measuring arterial injury in vitro porcine kidney in different sizes of nephrostomy tracts
Houmeng YANG ; Guohua ZENG ; Faming SHAO ; Qilong MIU ; Jianda YU ; Ningjun FANG ; Xun LI ; Xiaomei WU
Chinese Journal of Urology 2011;32(5):316-317
Objective To investigate the arterial injury in vitro porcine kidney to different size of nephrostomy tracts. Methods The technique of percutaneous nephrostomy was applied to establish 11 groups of different size of nephrostomy tracts from 12 F to 32 F,with 40 tracts in every group.The technique of digital subtraction angiography (DSA) was used to inspect and analyze arterial injury. Results In the range from 12 F to 32 F,the damage of arterial injury increased with the size of the tract diameter.In groups of 20 F and 32 F,the number of nephrostomy tracts with serious arterial injury was 18 (18/40) and 30 (30/40) respectively,and the difference was statistically significant (P<0.05).There was no statistical difference between groups 18 F、20 F、and 22 F. Conclusions The damage of renal arterial injury increased with the size of the nephrostomy tract.Atract of 20 F reduees arterial injury compared with a tract of 32 F.
10.Effect of Buyang Huanwu decoction and its simple prescription (Naojian tablet) on CDK4/Cyclin D1 expression of rats with cerebral ischemia.
Fang LIU ; Yu-hong WANG ; Guang-xian CAI ; Yan SHE ; Le SHAO ; Xiang-yi XIA
China Journal of Chinese Materia Medica 2015;40(20):4058-4062
To evaluate the regulating effect of Buyang Huanwu decoction and its simple prescription (Naojian tablet) on CDK4/Cyclin D1 expression in hippocampus tissues of rats with cerebral ischemia, SD rats were divided into the sham-operation group, the model group, the Buyang Huanwu decoction group (ig, 3.15 g · kg⁻¹) and the simple prescription group (ig, 2.41 g · kg⁻¹). Each group was further divided into five subgroups based on time points after the administration, i. e. 1 d, 3 d, 7 d, 14 d and 28 d, respectively. CDK4/Cyclin D1 expressions of the group at different time points were examined by using immunohistochemistry and real-time qPCR. According to the results, the cerebral ischemia model group showed higher CDK4/Cyclin D1 expression than the sham-operation groups (P < 0.05), suggesting that the cell cycle signal pathway would be activated by the cerebral ischemic injury. Both Buyang Huanwu decoction and simple prescription groups showed significantly lower cyclin expression than the model group at 3 d, 7 d, 14 d, 28 d (P < 0.05), indicating both Buyang Huanwu decoction and its simple prescription could play the neuroprotective effect through the cell cycle signal pathway.
Animals
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Brain Ischemia
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drug therapy
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genetics
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metabolism
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physiopathology
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Cell Cycle
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drug effects
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Cyclin D1
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genetics
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metabolism
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Cyclin-Dependent Kinase 4
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genetics
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metabolism
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Drugs, Chinese Herbal
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administration & dosage
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Humans
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Male
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Rats
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Rats, Sprague-Dawley