1.Application of psychological intervention in intravenous infusion of stimulant drugs in neurology
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):416-417
Objective To explore the application and effect of psychological intervention in stimulating intravenous infusion of drugs in neurology department. Methods In the control group, the patients in the neurology department selected appropriate stimulant drugs according to their actual conditions, and the patients in the study group received psychological intervention on the basis of stimulating drugs and intravenous treatment. Records the two groups of neurology patients treatment compliance, before and after treatment of neurological function changes, the data into the SPSS software, after statistical analysis, and draw conclusions. Results Before treatment, two groups of neurology patients were compared with the NIHSS scale score; after the treatment of nerve function improvement (NIHSS scale decline) than the control group, the study group (P<0.05). Department of neurology patients with complete compliance (82.61%) was significantly higher than the control group (50.00%, P<0.05). Conclusion On the basis of stimulating drugs intravenous infusion in the treatment of Neurology, patients with targeted psychological intervention can significantly improve the treatment compliance, and is conducive to the protection of patients with drug treatment effect.
4. Chemical constituents of Huoxiang Zhengqi Liquid
Chinese Traditional and Herbal Drugs 2011;42(11):2189-2192
Objective: To study the chemical constituents of Huoxiang Zhengqi Liquid. Methods: Silica gel column chromatography, preparative thin-layer chromatography, and recrystallization were used to isolate the chemical constituents from chloroform extract. And the structures of compounds were identified by spectral analysis and physicochemical properties. Results: Fifteen compounds were obtained and identified as liquiritin (1), liquiritigenin (2), isoliquiritigenin (3), formononetin (4), oxypeucedanin hydrate (5), byakangelicin (6), hesperidin (7), 5, 7, 8, 3′, 4′- pentamethoxyflavone (8), 5, 6, 7, 3′, 4′-pentamethoxyflavone (9), 5, 7, 8, 4′-tetramethoxyflavone (10), nobiletin (11), 3, 5, 6, 7, 8, 3′, 4′-heptamethoxyflavone (12), tangeretin (13), honokiol (14), and magnolol (15). Conclusion: All the compounds are isolated from Huoxiang Zhengqi Liquid for the first time. Compounds 1-4 may come from Glycyrrhizae Radix et Rhizoma; compounds 5 and 6 from Angelicae Dahuricae Radix; compounds 7-13 from Citri Reticulatae Pericarpium; and compounds 14 and 15 from Magnoliae Officinalis Cortex.
5.Effect of the number of CD34~+CD44~+ cells infusion on hematologic reconstitution after unrelated umbilical cord blood transplantation
Shao-Qing WU ; Can LIAO ; Shao-Ling GU ; Al ET
Chinese Journal of Organ Transplantation 1996;0(02):-
20?10 9/L) was observed (mean 41 days, range 12 to 118 days). There w as the association between the number of CD34 +CD44 + cells infusion and time to neutrophic recovery (?= -0.657 , P
6.Effect of Botulinum Toxin A Injection Guided by Peripheral Nerve Stimulation on Hemifacial Spasm: 57 Cases Report
Yinjin SHAO ; Yubin HUANG ; Guihua WU
Chinese Journal of Rehabilitation Theory and Practice 2016;22(3):323-325
Objective To investigate the effects of local injection of Botulinum toxin A (BTX-A) on hemifacial spasm guided by periph-eral nerve stimulation. Methods 57 patients with hemifacial spasm from January, 2012 to June, 2015 received local multi-point injection of BTX-A guided by peripheral nerve stimulation. The grades of facial spasm were evaluated before, 72 hours and 6 months after treatment. They were followed up for 3-9 months. Results The spasm reduced in the patients both 72 hours and 6 months after treatment (χ2=4.946, P<0.05). The incidence was 98.25% of satisfaction and 92.99% of very well 72 hours after treatment, while it was 91.23% and 78.95% 6 months after treatment. The relief of spasm was maintained for (23.1 ± 2.3) weeks. Conclusion Injection of BTX-A guided by peripheral nerve stimulation is effective on hemifacial spasm for a long time.
7.Mechanisms of Traditional Chinese Medicine in the Treatment of Neuropathic Pain
Cui SHAO ; Wei QI ; Zhibing WU
World Science and Technology-Modernization of Traditional Chinese Medicine 2015;(10):2151-2155
Neuropathy pain, or neuropathic pain (NP), which pathogenesis is complex and is lack of effective treatment, is one of common chronic pain in clinic. Studies of traditional Chinese medicine (TCM) in treating NP were increased in recent years. In the review, studies of treatments of TCM compound and monomer in NP during last decade were collected and analyzed to find out possible mechanisms, and some existing problems.
8.Modern Progress of Mechanism of Moxibustion Therapy
Junfeng ZHANG ; Yaochi WU ; Minghai SHAO
Journal of Acupuncture and Tuina Science 2006;4(5):257-260
Moxibustion therapy is one of the external therapeutic methods. In the present article, the pharmacological and physical actions of moxibustion therapy, and the effects of moxibustion therapy on immune system, blood circulation, inflammation, and body metaboly were reviewed.
9.Treatment of Lumbar Intervertebral Disk Herniation with Electric Acupuncture
Bimeng ZHANG ; Yaochi WU ; Ping SHAO
Journal of Acupuncture and Tuina Science 2007;5(4):216-220
To make objective evaluation on treatment of lumbar intervertebral disc herniation with electric acupuncture. Method: All 200 cases were randomly allocated into an observation group (100 cases) and a control group (100 cases). Cases in the observation group were treated with electric acupuncture. Cases in the control group were treated with oral administration of Mobic. Result: The total effective rate in the observation group was 86.5%,and the total effective rate of the control group was 75.0%. There was a significant difference between the two groups (P<0.01). Conclusion: Electric acupuncture is a safe and remarkably effective way for lumbar intervertebral disc herniation.
10.Effectiveness of multiplex ligation-dependent probe amplification assay used for detecting deletion of Prader-Willi syndrome
Hong SHAO ; Va LIP ; Bailin WU
Journal of Peking University(Health Sciences) 2005;37(1):64-67
Objective: Prader-Willi syndrome (PWS) is characterized by severe hypotonia and feeding difficulties in early infancy, followed by excessive eating and gradual development of morbid obesity in later infancy or early childhood. Patients with PWS are often too young to manifest sufficient features or have atypical findings, making genetic testing important to confirm the diagnosis of PWS. Approximately 99% of patients with PWS have a diagnostic abnormality in the parent-specific methylation imprint within the Prader-Willi critical region (PWCR) at chromosome 15q11.2-q12. Of them, 70% have a paternal deletion; 25% have a maternal uniparental disomy (UPD); and <5% have a mutation in the imprinting center. Methods: Current techniques can identify a diagnostic abnormality, such as paternal deletion or maternal UPD for most of patients with PWS, but they are labor-intensive and cost-expensive. Multiplex ligation-dependent probe amplification (MLPA) is a novel, simple, and cost-effective technique for analysis of relative quantification in a single assay, which has recently been applied for the detection of genomic deletions, duplications, and amplifications in a variety of genes. Results: Six out of 20 patients referred for genetic diagnosis of PWS were found to have a deletion by MLPA, confirmed by FISH and DNA methylation analysis with 100% concordance. Conclusion: MLPA's high sensitivity and specificity for deletion detection is the same as FISH or Southern blot based analysis. Additional collaborative effort for developing and validating the complete MLPA-PWS assay, for not only detecting deletion but also identifying methylation abnormality, is on going.