OBJECTIVE:To provide reference information for pharmacoeconomic studies in China.METHODS:To intro?duce the roles of budget impact analysis and financial impact analysis and the connection with cost-effectiveness analy?sis.RESULTS&CONCLUSION:Budget impact analysis can contribute to making innovative drug reimbursement decision.

OBJECTIVE:To explore WHO western pacific region to essential drugs available and the framework of regional action (2010～2015) and the implications of China's essential drug policy.METHODS:Discuss WHO western pacific region to essential drug available and the framework of regional action of 2010～2015,and to help WHO western pacific regional expert consultation of member states including China can obtain the essential drug which was afforded,quailty assurance,use properly,fair,and available.RESULTS & CONCLUSION:As a key member of WHO western pacific region,we support the plan and framework,but we need to do with the implementation of national conditions.

Objective: To compare utility values measured by different instruments. Methods: Different instruments were used to measure utility values in 350 patients who were diagnosed as age-related macular degeneration at the same time. The median of utility values measured by different instruments was regarded as relative standard utility value to process comparison, analysis of variance, correlation analysis and curve estimation. Results: Most differences and correlations among utility values measured by different instruments were significant, as well as equations estimated from relative standard utility value and utility values measured by different instruments, but the degree of fitting was not high. Conclusion: The utility values of the same subject measured by different instruments are quite different. The results of the study could provide correction reference to the utility value measured by single instrument in the absence of absolute standard.

OBJECTIVE:To provide reference for choosing appropriate methods of health outcome measurement in phar?macoeconomic evaluation.METHODS:To compare different outcome measurement methods and introduce the standards in varied pharmacoeconomic guidelines.RESULTS&CONCLUSION:We should choose those methods according to different health systems,angles of research and disease specialities.

OBJECTIVE: To provide information about the reforming basic insurance drug list in China, especially in Shanghai for reference.METHODS: To introduce development of drug classified management in China and compare different experiences in the management of OTC drugs' reimbursement in Sweden, Germany, Netherlands and Fenland .RESULTS & CONCLUSION: The inclusion criteria of OTC drugs' reimbursement must be identified.OTC drugs within the insurance drug list should be equated with Rx drugs and those out of the insurance drug list should be fixed with favourable prices.

OBJECTIVE: To provide reference information for formulating drug policies in China.METHODS: To introduce the development and application of pharmacoeconomics in drug pricing and reimbursement process in Asia - Pacific region. RESULTS & CONCLUSION:Pharmacoeconomics can aid for drug policy decision.

OBJECTIVE:To provide reference information for development and application of pharmacoeconomics evaluation in China.METHODS:To introduce the different roles of pharmacoeconomic evaluation in the world.RESULTS &CONCLUSION:It's necessary for China to formulate pharmacoeconomic guidelines and use it in drug pricing,drug reimbursement,clinical guidance,diseases prevention and new drug R&D.

OBJECTIVE:To evaluate the medical cost of capectabine in treatment of advanced rectocolonic carcino?ma.METHODS:The characteristics of therapeutic effect and medical cost were compared between capectabine and classical MAYO program.RESULTS&CONCLUSION:The capectabine is more expensive than traditional drugs,however,in terms of medical resource,the saving medical cost in use of capectabine would counterbalance the expensive price of drug to maxium limit.The medical cost of capectabine is superior to that of traditional drugs.

The paper undertakes a study of equity in the distribution of health resources in China by means of the Theil Index. The results indicate that equity in the distribution of hospital beds, doctors, and nurses between the various provinces is taking a turn for the better. The improvement of equity in the distribution of hospital beds and doctors is mainly due to the improvement in the eastern regions while the central and western regions still maintain the status quo, with supply basically meeting demand. The improvement of equity in the distribution of nurses, however, is due to the simultaneous improvement in the eastern, central and western regions, yet demand exceeds supply.

OBJECTIVE:To evaluate the cumulative incidence of end-stage renal disease(ESRD)in Chinese hypertensive type2diabetic patients with microalbuminuria(DHM)treated with different regimes,and to provide reference for decision makers.METHODS:A peer-reviewed Markov model that simulated progression from microalbuminuria to nephropathy,dou?bling of serum creatinine,ESRD,and all-cause mortality in patients with DHM was adapted to China.Three strategies were compared:(1)early use of irbesartan(i.e.prompt treatment in subjects with microalbuminuria);(2)late use of irebesartan(i.e.as from overt nephropathy);(3)standard hypertension care(with comparable blood pressure control).Cumulative incidence of ESRD,costs and life expectancy were projected for a hypothetical cohort of1000subjects.Treatment-specific progression and mortality probabilities were derived from published trials:IRMA-2(in microalbuminuria)and IDNT(in overt nephropathy).Medical management and cost data per state were obtained from published local sources.A flexible time horizon up to25years and third party payer perspective were used.Future costs and LE were discounted at3%yearly.RESULTS:When compared with standard blood pressure control,early use of irbesartan was evaluated to reduce the cumulative incidence of ESRD from(mean?standard deviation)8%to22%,save RMB30348(US＄3667),and add0.638life years per treated patient.Late use of irbesartan was dominant over control group but dominated by early irbesartan.Break-even occurred after13years.CON?CLUSION:Treating DHM patients by early use of irbesartan is evaluated to reduce the incidence of ESRD,extend life and reduce costs.Treating patients at a later stage is still beneficial,however to a lower extent.