1.Autonomic Nervous Response to Cold Provocation in Vibration-Induced White Finger(VWF) Patients with HRV Analysis
Jin LUO ; Hisataka SAKAKIBARA ; Shankuan ZHU
Space Medicine & Medical Engineering 1999;12(1):6-9
Objective To evaluate the autonomic nervous response of Vibration-induced white finger(VWF) patients to cold provocation test by power spectral analysis of heart rate variability(HRV).Methods The cold provocation test was conducted in 22 VWF patients and 19 healthy volunteers.ECG was recorded during the experiment,and converted to R-R interval signals after the experiment.The normalized LF[(0.02~0.15) Hz]component power,normalized HF[(0.15~0.40) Hz] component power and the ratio of LF to HF power(LF/HF ratio) were calculated.Results At the beginning of cold exposure,there were a significant decrease of HF% in both groups,and a significant increase of LF/HF ratio in VWF group as compared with pre-exposure value.The LF/HF ratio in VWF group during cold exposure was significantly higher than that in the control group.Conclusion Cold stimuli induced depression of parasympathetic nervous system in both groups,and the sympatho-vagal balance was maintained in the control group,but in VWF group it became sympathetic dominance during cold exposure.The sympathetic nervous system of VWF patients may be hyperreactive to cold stimuli.
2.Strategic considerations of medical science and technology during the 'Twelfth Five-year' Plan period
Wei ZHU ; Qifeng CAO ; Weihang MA ; Shankuan ZHU
Chinese Journal of Medical Science Research Management 2011;24(4):219-223
Medical science and technology are important as they concerns people's life. Innovation of medical science and technology is therefore significant for the development of the science and technology. This article discussed the current situation of medical science and technology in China,and analyszed its opportnities and challenges. In addition, strategies for its development during the Twelfth Five-year Plan period are proposed, namely, to develop HLS, construct the innovative systems of medical science and technology, and to promote the coordinated development of the medicine and science and technology.
3.Influence of Life-related Factors and Participation in Health Examination on Mortality in a 4.5-year Follow-up of a Rural Cohort
Shankuan ZHU ; Takaaki KONDO ; Hisataka SAKAKIBARA ; Koji TAMAKOSHI ; Kunio MIYANISHI ; Nao SEKI ; Naohito TANABE ; Hideaki TOYOSHIMA
Environmental Health and Preventive Medicine 2000;5(2):66-71
To identify life−related factors causing increased mortality, 2, 769 rural residents aged 29−77 were investigated through a self−administered questionnaire in 1990. Death certificates and migration information were inspected during the 4.5−year follow−up period. Age, obesity, life attitude, job, marital status, drinking and smoking habits, previous or current illness, and frequency of participation in health examinations were checked during the baseline survey. The person−year mortality rate was higher among irregular participants in health examinations than among regular participants both among males and females. From Cox’s multiple regression analysis, factors with a significantly high hazard ratio (HR) for mortality were irregular participation (HR=2.05), increase of age (HR=1.54, for 10 years), previous or current illness (HR=2.44), unemployment (HR=1.95), and living without a spouse (HR=2.61) for males; and for females they were having previous or current illness (HR=15.21) and living without a spouse (HR=2.94). Thus, irregular participation in health examinations, unemployment and aging showed a relationship with a higher mortality only in males. A previous or current illness and living without a spouse were related in both sexes.
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