1.Therapeutic efficiency of short anterior urethral stricture treated with endourethral surgery combined with iridium 192 radiotherapy
Weixing QU ; Dalin HE ; Shangshu DING ; Yongyi CHENG ; Qing WANG
Journal of Pharmaceutical Analysis 2010;22(4):281-282,封3,封4
Objective To assess the therapeutic efficiency of short anterior urethral stricture treated with endourethral surgery combined with iridium 192 radiation therapy in order to decrease the recurrence rate after endourethral surgery. Methods A total of 286 patients with anterior urethral stricture (stricture length ranging from 0.5 to 2.5cm, averaging at 1.6cm) were divided randomly into two groups after internal urethrotomy and cicatrix electrotomy. The radiation group of 173 patients was treated as soon as possible with iridium 192 radiation therapy on the stricture sections while the control group of 113 patients was not. The recurrence rate was compared between the two groups during one year's follow-up. Results Among all the 286 successful operations, stricture recurred in 19 patients of the radiation group (recurrence rate of 10.98%) and in 62 ones of the control group (recurrence rate of 54.86%), with a significant difference (P=0.003). Conclusion It is an effective way to prevent recurrence by treating patients as early as possible with iridium 192 radiation on the stricture sections after endourethral operation on anterior urethral stricture.
2.Effect of Interactive Somatic Game Kinect on Lower Limbs Rehabilitation after Stroke
Shangshu WANG ; Changxiang CHEN ; Weihong ZHANG ; Suhui MA ; Jinxian XU
Chinese Journal of Rehabilitation Theory and Practice 2013;19(7):658-661
Objective To observe the effect of interactive somatic game Kinect on motor of lower limbs and balance function in patients with stroke. Methods 40 inpatients were divided into experimental group (n=20) and control group (n=20). All the patients received routine rehabilitations, while the experimental group received the interactive game Kinect in addition. They were assessed with Fugl-Meyer assessment of lower limb (FMA) and Berg balance scale (BBS) before and after intervention. Results The scores of flexor synergy, extensor synergy,movement combining synergies (in sitting), lower limb total score of FMA, and the score of BBS increased more in the experimental group than in the control group (P<0.05) after intervention. Conclusion The interactive somatic game Kinect can further improve the motor of lower limb and balance function of patients with stroke.
3.Correlation between Glutathione S-transferase Polymorphisms and Sperm DNA Integrity in Male Patients with Idiopathic Infertile
Huan WANG ; Fa SUN ; Junping XING ; Shangshu DING ; Chao SUN ; Xinyang WANG ; Tiejun ZOU ; Kaifa TANG
Journal of China Medical University 2015;(12):1075-1078
Objective to investigate the correlation between glutathione S- transferase gene M1,t1 and P1(GStM1,GStt1 and GStP1)poly-morphism and sperm DNA fragmentation index(DFI)in male patients with idiopathic infertile. Methods the study included 246 male patients with idiopathic infertility. Polymerase chain reaction(PCR)and polymerase chain reaction restriction fragment length polymorphism(PCR-RFLP) were used to identify the genotype of GStM1,GStt1 and GStP1,respectively. Sperm DFI was analyzed by flow cytometry with acridine orange staining. Results the sperm DFI was significantly higher in GStt1 gene null type group than in GStt1 gene wild type group(P < 0.01);and there were no significant differences in GStM1 and GStP1 gene mutation type groups when comparing with the wild type group(P > 0.05). Conclusion GStt1 gene deletion was positive associated with the sperm DFI in male idiopathic infertile patients.