Objective: To study the MRI signal changes of hysteromyoma before and after treated by high-intensity focused ultrasound (HIFU), evaluate the effects of HIFU treatment and providing the reference for clinical therapy. Methods:MR scan and enhanced-scan were performed by GE SignaHDe 1.5T MR system on 83 patients with hysteromyoma (a total of 117 myomatas) before and after HIFU treatment within one week. Through the observation of whether there were coagulation necrosis and blood supply diminution to evaluate the effects of HIFU treatment. The appearance of coagulation necrosis and blood supply diminution meant a remarkable therapeutic effect, and vice versa. Results:By analyzing the MR images of 83 patients with hysteromyoma (a total of 117 myomata) treated by HIFU from March 2012 and November 2012, we found that 106 myomata’s MRI signals clearly changed, from low signal to slightly high or equal signal on T1WI, from low signal to low or slight high signal on T2WI, which meantcoagulation necrosis and blood supply diminution. Besides, the rest 11 myomata’s MRI signal showed no changes before and after HIFU treatment on both coagulation necrosis and blood supply diminution. Conclusion:MRI is the most effective methods on evaluating the effects of HIFU treatments.

"PRC Law on HIV/AIDS Prevention and Control" came into force on March 1, 2006. According to the law, iatrical workers should take every patient and sample as infected ones to assure iatrical biosafety and should not discriminate against people living with HIV/AIDS. HIV/AIDS patients have the right to accept therapy in hospitals and iatrical workers were not allowed to refuse them by using any reason. If the law was not well performed by iatrical workers, they will be punish and even accept penal punishment. Iatrical workers should act as the rules stated by the law and know the rights and incumbencies to provide the stable foundation for the prevention and treatment of HIV in our country.

Objective:To investigate the effects of calcineurin signaling pathway on the collagen synthesis of rat cardiac fibroblasts(CF) induced by arginine vasopressin(AVP). Methods:CF of neonatal Sprague-Dawley rats were secured by trypsinization and Cultured.Collagen content of CF culture medium was estimated by hydroxyproline colorimetry.Calcineurin activity was determined with spectrophotometer.Results:① AVP increased the content of hydroxyproline in culture medium of CF in a concentration dependent manner.But in the presence of 0.5 ?g/ml cyclosporin A(CsA),the specific inhibitor of calcineurin,the hydroxyproline content of culture medium in corresponding AVP+CsA group was significantly lower than that of 10~(-7) mol/L AVP or 10~(-6)mol/L AVP group(both P

OBJECTIVE To investigate the risk factors of deep fungal infection in intensive care unit(ICU)and discuss the strategy of this disease control.METHODS A total of 502 patients with the risk factors of deep fungal hospital infection from Jan 2001 to Dec 2006 were investigated with retrospective method.RESULTS The percentage of deep fungal infection in early preventive treatment group was 7.9%,but it was 16.2% in the control group.CONCLUSIONS To early prevent the deep fungal infection with the risk factors plays a great role in prevention and treatment of the patients with deep fungal infection in intensive care unit.

The HIV/AIDS epidemic in China has entered the Widespread Epidemic Period.HIV-infected cases have been reportedly found in all 34 provinces(minority autonomous regions/municipalities).HIV is spreading from high risk group to general population.Our government has paid much attention to AIDS prevention and control,lots of effective measures have been carried out,and comprehensive prevention.treatment,bealth care and financial support have been launched.Relatively consummate surveillance system and laboratory testing network of AIDS have been established at present and large SCale of ARTs have been carried out through the whole country.There is a great change in the situation on AIDS Prevention and Control in China.

Mycoplasma pneumoniae (MP) is an important etiological agent in childhood community acquired pneumonia. Pediatricians are concerned about the clinical problems of MP infection. In this review,MP infection-related clinical issues, such as epidemiology, pathogenesis, clinical features, imaging, and relationship of bronchial asthma, laboratory diagnosis and treatment, were discussed to improve pediatricians' awareness and knowledge of clinical diagnosis and treatment of MP infection.

Objective To investigate follow-up willingness of patients and their families after discharge.Method A follow-up willingness questionnaire for cancer patients and their families was designed,the items covering follow-up willingness,follow-up methods, follow-up time,follow-up demand for content etc.Results Ninety-three point nine percent of patients and 96.9%of families were willing to accept follow-ups;84.8%of patients and 81.3%of families were willing to accept follow-ups by phone calls;42.4%of patients and 43.8%of families were willing to take follow-ups at any time,33.4%of patients and 40.7%of families would like the follow-up in the afternoon or evening.69.7%of patients and 62.4%of families would like the follow-ups of 5 to 10 minutes. 97.0%of patients and 93.8%of families were willing to take the phone call follow-ups by physicians and 33.3%of the patients,31.2%of their families by nurses.In terms of contents,the patients and families were willing to have the medication instructions,re-examination reminder,appointments for hospitalization,dietary guidance,health counseling,exercise guidance,psychological counseling and nursing on complications and PICC.There was a high consistence on follow-up contents after discharge in cancer patients and their families(all P>0.05).Conclusion The hospitalized cancer patients and their families are willing to take telephone follow-up after discharge by the hospital staff,but most choose to have follow-ups by a doctor.The follow-up contents are multifaceted.

Particular difficulties were presented when diagnosis of asthma in children under 5 was made. Diagnosis of asthma in early childhood is a big challenge and has been based largely on clinical justification and assessment of symptoms and physical signs. The PRACTALL consensus report focus exclusively on pediatric asthma, such as natural history and pathophysiology of pediatric asthma, different patterns of recurrent wheeze in pediatric patients, different phenotypes of asthma in children, and provides recommendations for diagnosis, practical management and monitoring. More factors should be considered for diagnosis of asthma in children under 5, including the patterns of recurrent wheeze, history of atopy, risk factor of asthma, long-term follow-up, extensive differential diagnoses, response to bronchodilator and/or anti-inflammatory treatment and so on.

This article is trying to find out the historical and realistic reasons of the restriction of the process of modernization of traditional Chinese medicine (TCM) from the history of TCM theory and practice of TCM institutional setup and related policies and many other aspects.Then it points out that the TCM in the background of the development of science and technology today is already has the necessary conditions of modernization,but the process can not be succeed overnight,it ought to be a systematic engineering.

Objective To study the frequency of CYP2C19 genotype and allele mutation of cytochrome P450 in the southeast part of Henan province,and to understand the effect of sex,age,body mass index (BMI)on the genetic polymorphism of CYP2C19.Methods Genetic polymorphism analysis of CYP2C19 gene in 161 healthy people in Henan province,using gene chip method,87 male,74 female,aged 26 -82 years old,and BMI 17 -31. Results The experiment,a total of CYP2C19 six different gene mutation type,CYP2C19 1 of (40.4%),CYP2C19*1 /*2 (39.1%),CYP2C19 *2 /*2 (14.9%),CYP2C19 *1 /*3 (3.1%),CYP2C19 *2 /*3 (2.5%), CYP2C19*3 /*3 (0%);allelomorph CYP2C19 * 2 (35.7%),follow (2.8%).87 male wild type homozygous for CYP2C19 1 of (39.1%),allelomorph CYP2C19 * 2 (39.1%),follow (3.1%),74 female wild type homozygous for CYP2C19 1 of (41.9%),and other allelomorph CYP2C19 * 2 (32.3%),follow (2.5%).103 cases were more than or equal to 58 years old wild type homozygous for CYP2C19 1 of (47.6%),allelomorph CYP2C19 * 2 (39.8%),follow (3.7%),58 <58 years old wild type homozygous for CYP2C19 1 of (27.6%),and other allelo-morph CYP2C19 * 2 (31.7%),follow (1.9%).BMI >25 groups of wild -type homozygous for CYP2C19 1 of (37.7%),allelomorph CYP2C19 * 2 (32.9%),follow (1.2%),BMI <25 groups of wild -type homozygous for CYP2C19 1 of (42.4%),and other allelomorph CYP2C19 * 2 (38.5%),follow (4.3%).Conclusion There was no significant difference in the genotype of CYP2C19*2 between the BMI and *3 in the southeast part of Henan province.