Boettcherisca peregrine, as a fly with the necrophagous habits found on human corpses and a vector of disease or parasitic, myiasis-producing agent, is a significant flesh fly species in forensic entomology and medical context. This study reviewed the various aspects of this fly species, including morphology, bionomics, molecular analysis, medical and forensic entomology involvement, such as morphological characteristics of larva, puparia and adult, developmental rate of larvae, the effects of heavy metal (such as Cd and Cu) on the growth and developmentin of larvae, and the impact of some specific stimulis on the labellar chemosensory hair of B. peregrina. Species identification, gene and functions, myiasis and forensic case of this species were also outlined. Therefore, the paper has an important implication for improving the role of B. peregrina in medicine and forensic science.