1.Progress in the treatment for thyroid microcarcinoma.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2013;27(8):442-445
Thyroid microcarcinoma(TMC) refers to the diameter less than 1cm in thyroid cancer. In recent years, with high frequency ultrasound and pathology diagnosis technology development and improvement, the incidence of TMC increased dramatically. However, there are a lot of controversy about its complication, treatment methods and value of treatment both in domestic and abroad. In this paper,we review literatures in the passed 5 years both in domestic and abroad, and investigated the progress of treatment for TMC. Agreement on the view: routine central lymph node dissection should be done regularly in the treatment thyroid microcarcinoma.
Humans
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Thyroid Neoplasms
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surgery
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therapy
2.Effects of lipid microspheres prostaglandin E1 on microcirculation deficit of subarachnoid hemorrhage
li, WEN ; shan-quan, LI ; jiong, DAI
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(03):-
Objective To investigate the effects of lipid microspheres prostaglandin E1(Lipo PGE1) on subarachnoid hemorrhage(SAH).Methods Ninty-three patients with SAH were randomly divided into control group(treated with nomal drugs) and Lipo PGE1 treatment group(treated with nomal drugs and Lipo PGE1).Changes in neuroimaging,biochemical indexes and incidence of cerebral vasospasm were measured. Results A lower incidence rate of cerebral vasospasm was observed in Lipo PGE1 treatment group(P0.05).The levels of vWF and GMP-140 were significant lower in the Lipo PGE1 treatment group than those in the control group after treatment for 3 and 7 d(P
3.Influence of lipid microspheres prostaglandin E1 on somatosensory evoked potential in subarachnoid hemorrhage
li, WEN ; shan-quan, LI ; jiong, DAI
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(03):-
Objective To investigate the changes of somatosensory evoked potential(SEP)in subarachnoid hemorrhage(SAH)and in-fluence from lipid microspheres prostaglandin E1(Lipo PGE1). Methods Ninty-three patients with SAH were randomly divided into control group(treated with nomal drugs) and Lipo PGE1 treatment group(treated with nomal drugs and Lipo PGE1).Clinical outcomes and changes of SEP before and after the treatment were observed. Results After the treatment,the latency of N20 wave was prolonged in both groups(P
4.Clinical therapeutic observation of doxazosin mesylate in treatment of vesical spasm in 256 patients undergoing surgery for relieving bladder outlet obstruction
Shan HUANG ; Junping YANG ; Quan CHEN
Chinese Journal of Geriatrics 2010;29(9):748-749
Objective To study the preventive and therapeutic effect of doxazosin mesylate (Cardura) in the management of vesical spasm. Methods Two hundred and fifty six cases were randomized into two groups: the study group was given Cardura 4 mg at bedtime, while the control group was given probanthine 15 mg twice a day. All the patients were given 8 ng of Vitamin Ks three times a day. Results There was significant difference in the incidence of vesical spasm between study group and control group (P<0.01). Conclusions Cardura can decrease the urethral closure pressure, and reduce excitability of bladder detrusor muscle. So it is effective for the relief of vesical spasm.
6.Analysis of risk factors of severe retinopathy of prematurity
Hai-Dong SHAN ; Pei-Quan ZHAO ; Dingfeng JIANG ;
Chinese Journal of Ocular Fundus Diseases 2003;0(05):-
4 days, so it is recommended to screen such premature infants carefully.
7.Effects of bFGF on cognitive ability of rat with diffuse axonal injury
li, WEN ; jiong, DAI ; wei-yi, HU ; shan-quan, LI
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(03):-
Objective To study the alterations in neurobehavior of rats with diffuse axonal injury(DAI) and to evaluate the potential role of basic fibroblast growth factor(bFGF). Methods A weight-drop device was employed to build the DAI model.An injection of bFGF subdurally and subcortically was given to the bFGF therapeutic group(n=60).Besides,normal control(n=20) and injured control group(n=60) were established.The elevated walkway test,prehensile traction test,sensorimotor integration test and the Morris' water maze test were adopted to examine the motor and memory abilities.After the implantation of skull electrodes,P3-like potential was explored in rats before and after injury. Results After DAI,the scales of the elevated walkway test,prehensile traction test,sensorimotor integration test and the Morris' water maze test were decreased,and the rats in the bFGF therapeutic group presented a better behaviour in the early stage.The latency of P3-like potential prolonged significantly in rats with DAI,with the P3-like potential in the injured control group longer than that in the bFGF therapeutic group(P
8.Effects of bFGF on alterations in pathology and immunohistochemistry in rats with diffuse axonal injury
li, WEN ; jiong, DAI ; wei-yi, HU ; shan-quan, LI
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(03):-
Objective To study the alterations in pathology and immunohistochemistry in rats with diffuse axonal injury(DAI) and the effects from basic fibroblast growth factor(bFGF). Methods A weight-drop device was employed to produce DAI in rats.In the treatment group(n=60),bFGF was injected subdurally and subcortically.Besides,normal control group(n=20) and injury-control group(n=60) were also established.The pathological changes were observed by light microscopy and electromicroscopy,and the expression of brain-derived neurotrophic factor(BDNF),growth associated protein-43(GAP-43) and glial fibrillary acidic protein(GFAP) were also examined by immunohistochemistry. Results Typical pathological changes were observed in the basal portion of pons,corpus callosum and white matter of cerebral hemisphere in the rats with DAI.And an upregulation of GFAP,GAP-43 and BDNF was also found.In the treatment group,better outcomes of pathological changes were observed.bFGF increased the expression of BDNF and GAP-43,while inhibited the immunoreactivity of GFAP. Conclusion Topical application of bFGF can improve brain tissue regeneration and speed function recovery in rats with DAI,though its long-term effect warrants further study.
10.Clinical study on doxofylline injection in treatment of children with acute asthma attacks.
Jia-xiang ZHANG ; Hui-quan LIN ; Jin-shan CHEN
Chinese Journal of Pediatrics 2004;42(2):143-144
Acute Disease
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Asthma
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drug therapy
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Bronchodilator Agents
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administration & dosage
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adverse effects
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therapeutic use
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Child
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Child, Preschool
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Female
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Humans
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Infant
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Infusions, Intravenous
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Male
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Theophylline
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administration & dosage
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adverse effects
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analogs & derivatives
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therapeutic use
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Treatment Outcome