Follicular lymphoma (FL) is a type of B lymphocytic non-Hodgkin lymphoma.Clinically,FL presents with long course,indolent behavior,and is characterized by prompt response to initial therapy but almost invariably subsequent relapses.It is considered incurable with conventional therapies.Appropriate treatment strategies are critical for survival.Recently,several drugs such as rituximab,and bendamustine have been approved for FL treatment.Very promising novel agents like ofatumumab,epratuzumab,lenalidomide,bortezomib and ABT-263 are now under investigation in clinical trials and will provide more choices for FL therapy.

Objective To analyze the clinical effect and side effect of the placement of Jenefox intrauterine device(IUD) following artificial abortion.Methods Making follow-up observation on 783 women having been pregnant for 5～12 weeks and undergoing placement of Jenefex IUD following artificial abortion.Results Among 783 cases,3 cases expulsion of intrauterine device,4 cases pregnancy with intrauterine device,21 cases unlode with sign,36 cases increased excretion,23 cases hypogastralgia,19 cases prolonged menstrual period,12 cases dropping bleeding,6 cases of increased menstrual bleeding.Conclusion Cases of women undergoing placement of Jenefox intrauterine device following artificial abortion have certain clinical effect and little side effect,and deserve to perform in clinic.

Objective To analyze the morphologic characteristics of the single infarct in the territory of perforating arteries which arise from the middle cerebral artery (MCA),and further to investigate the association between the type of cerebral infarction and the isolated stenotic disease of the ipsilateral MCA.Methods Fifty-five patients with acute ischemic stroke who were admitted to the Department of Neurology,Peking Union Medical College Hospital,Beijing,China during January 1,2005 and December 31,2006 were identified.All of the patients had a single acute infarction in the territory of the MCA perforating arteries revealed on diffusion weighted imaging (DWI).Transcranial Doppler (TCD) and magnetic resonance angiography (MRA) were performed for all patients.Patients with stenesis >50% of proximal internal carotid artery and potential cardiac sources of embolism were excluded from the study.Patients were classified into 2 groups according to the presence of the atberosclerotic stenosis of the ipsilateral MCA: patients with or without MCA stenosis.Size of the lesions was measured including the diameter,area and volume.The infarcts with a diameter less than 2 cm were classified as lacunar infarcts; those bigger than 2 cm were classified as the striatocapsular infarcts.The infarcts on DWI was seen in basal ganglia,the body of lateral ventricle and beth.The concomitance of subcortical multiple small old infarcts or leucoariosis on T2>WI-MRI between the two groups was assessed.Results Among these 55 patients,14 (25.5%) had stenosis of the ipsilateral MCA and 41 (74.5%) had a normal MCA.In the group of MCA stenosis,71.4% patients were lacunar infarcts; 67.3% patients were also lacunar infarcts in the normal MCA group.There was no significant difference between the two groups (χ2=0.147,P=0.701).No significant difference in the diameter,area and vo|ume of the infarcts was found between the two groups.The basal ganglia,the body of lateral ventricle and both of these places involvement accounted for 31.7% ,17.1%,51.2% in the normal MCA group; 35.7%,28.6%,35.7% in the stenotic MCA group.No significant difference was found (χ2=1.272,P=0.529).Twenty-three (56.1%) patients had concomitant of small old subcortical multiple infarcts or leucoariosis in the normal MCA group and 3 (21.4%) in the MCA stenosis group,and there was a significant difference between the two groups(χ2=5.033,P=0.025).Conclusions A series of pathologic mechanisms are supposed to cause the single infarction in the territory of MCA perforating arteries.Stenosis of MCA is an underlying cause in addition to perforating artery diseases.There is no significant difference in the size,volume or distribution of the lesions between the two groups.The concomitant of subcortical multiple small old infarcts or leucoariosis may demonstrate the perforating artery disease.

Carotid endarterectomy (CEA) can effectively treat symptomatic carotid stenosis, however, perioperative stroke is the most important complication of CEA. The microemboli generated before and after the operation are the most important reason for causing perioperative stroke. In addition, the hypoperfusion and postoperative hyperperfusion syndrome caused by intraoperative clipping of carotid artery, as well as carotid restenosis or occlusion after CEA are all the causes of perioperative stroke. As a non-invasive, real-time monitoring tool, transcranial Doppler (TCD) can be widely used in intraoperative monitoring of CEA, It is able to detect a variety of perioperative blood flow changes and the production of microemboli, and thus effectively predicts the occurrence of perioperative stroke, and decreases the risks of perioperative stroke.

Objective To observe the clinical efficacy of acupuncture-moxibustion in treating chronic non-bacterial prostatitis (CNBP), and its effect on the inflammatory cytokines in prostatic fluid. Methods A hundred CNBP patients were randomized into a treatment group and a control group, 50 in each group. The control group was intervened by oral administration of Tamsulosin Hydrochloride sustained-release capsules, while the treatment group was additionally treated with acupuncture-moxibustion. After 28-day treatment, changes of IL-6, IL-8, IL-10, IFN-γ, COX-2, PGE2, TNF-α, MIP-2, and iNOS contents were observed, and the clinical efficacies were compared. Results The IL-6, IL-8, IL-10, IFN-γ, COX-2, PGE2, TNF-α, MIP-2, and iNOS contents were significantly changed after intervention in both groups (P<0.05). The contents of IL-6, IL-8, IFN-γ, COX-2, PGE2, TNF-α, MIP-2, and iNOS contents in the treatment group were significantly different from those in the control group after intervention (P<0.05). The total effective rate was 89.4% in the treatment group versus 78.3% in the control group, and the difference was statistically significant (P<0.05). Conclusions Acupuncture-moxibustion is an effective method in treating CNBP, and can improve the associated indexes of prostatic fluid.

Bmi-1 is a core member of the polycomb group genes.As a proto-oncogene,Bmi-1 plays an important role in cell self-renewal,proliferation and apoptosis.Several studies have shown that Bmi-1 is highly expressed in some head and neck malignant tumors,such as nasopharyngeal cancer and laryngeal carcinoma.Furthermore,the expression level of Bmi-1 is closely related to the occurrence,development,incursion and prognosis of tumor.Bmi-1 is expected to become a novel tumor molecular marker,and provides a new direction for the treatment of the head and neck malignant tumor.

Standardization management of the procurement,supply,maintenance,filing,rejection and measurement of medical equipment is very important for determination of the right obligations and responsibilities of medical equipment management facility. It also avails to establish a set of systemic regulations to improve the performance of medical equipment facility and the continuous education of medical engineering technicians.

Objective To design a civilian-military remote medical consultation system to realize the networking between military and civilian hospitals.Methods Based on the remote consultation platforms of the PLA and Xinjiang Medical University the system was developed with B/S architecture,Java and C ++.Results The system realized the networking between civilian and military hospitals,which facilitated the outpatient diagnosis,hospitalization,operation planning,postoperative nursing,health education and etc.Conclusion The system enhances medical services and advances medical sources to flow to the elementary facilities,and thus is worthy promoting practically.

Aimed at the importance and current situation of hospital medical equipment management, the paper has analyzed the method of application and advantages of two dimension code technology and intelligent terminal in the management of medical equipment. And the two dimension code conversion software, which was developed by using C++ language compiler software and medical equipment management system, could achieve two dimension code information conversion and label production of medical equipment for instruction, maintenance, meterage and scraping and other information. And the intelligent terminal couldbe used to obtain information in real time, and it could combine with the existed one dimensional code to achieve informationization management for medical equipment, and then gradually replace one dimensional code. Through discussed the advantages of two dimension code and compared with the traditional model, the results indicated that this technology could provide a new direction in developmental trends and application prospect, and enhance the management level for dynamic information, and solve the problems of inconvenience in updating information.

Objective: To discuss the clinical significance of plasma von Willebrand factor (vWF), vascular endothelial growth factor (VEGF), and matrix metalloproteinase-9 (MMP-9) in patients with cerebral infarction in the process of occurrence and development of cerebral infarction. Methods: Thirty patients with cerebral infarction were divided into 3 groups according to their size of infarction: large infarction, moderate infarction, and small infarction (ten patients in each group). Enzyme-linked immunoadsordent assay (ELISA) was used to detect the concentrations of plasma vWF, VEGF, and MMP-9 in patient with cerebral infarction and in 20 healthy controls on day 1, 3, 7, and 15. Results: The mean levels of vWF (216 ± 62) μg/L, VEGF (584 ± 151) ng/ L, and MMP-9 (287 ± 147) μg/L in the cerebral infarction groups were significantly higher than those in the control group [vWF (96 ± 12) μg/ L, VEGF (111 ± 17) ng /L, and MMP-9 (102 ± 14) μg/L; P < 0.01]. The changes of plasma concentrations of the above 3 factors were correlated positively with the volume of cerebral infarction at the same time point in early cerebral infarction (r = 0.496, r = 0.519, r = 0.472 respectively; all P < 0.01). Conclusion: The concentrations of plasma vWF, VEGF, and MMP-9 were associated with the volume of cerebral infarction.