To analyze the sex and STDs, premarital sexual status and attitudes of students of a medical university with survey data collected.Methods: 1850 questionnaires were issued and 1850 valid responsive sheets were collected. Results: Of all the respondents, 16.8% with premarital sexual behavior, 46.56% once took some contraceptive measures, 25.57% adopted outside ejaculation, 50.49% thought that masturbation was harmful, 15.68% of them couldn't answer some questions correctly about sex and reproductive health. The result shows that taking sex and reproductive health education for college students are necessary. Parents and schools should recognize and take the responsibility of sex education for the younger generation.