Sexually transmitted diseases (STDs) are the most common group of identifiable infectious diseases in many countries. Adolescents and young adults (15-24 years old) comprise only 25% of the sexually active population but represent almost 50% of all newly acquired STDs. In a law for prevention of infectious diseases in Korea, STDs include syphilis, gonorrhea, chancroid, nongonococcal urethritis, clamydial infection, genital herpes, and genital wart. Bacterial vaginosis, trichomoniasis, candidiasis, amebiasis, scabies, phthiriasis, granuloma inguinale, AIDS, and high risk human papilloma virus are also included in the STDs. Individuals infected with STDs are 5-10 times more likely than uninfected individuals to acquire or transmit HIV through sexual contacts. Their control is important considering the high incidences of acute infections, complications, and sequelae, their socioeconomic impact, and their role in increasing transmission of the HIV. The purpose of this paper is to summarize the treatment and management of STDs on the basis of Centers for Disease Control and Prevention treatment guidelines for sexually transmitted diseases published in 2006.
Adolescent ; Amebiasis ; Candidiasis ; Centers for Disease Control and Prevention (U.S.) ; Chancroid ; Communicable Diseases ; Condylomata Acuminata ; Gonorrhea ; Granuloma Inguinale ; Herpes Genitalis ; HIV ; Humans ; Incidence ; Jurisprudence ; Korea ; Papilloma ; Scabies ; Sexually Transmitted Diseases ; Syphilis ; Urethritis ; Vaginosis, Bacterial ; Viruses ; Young Adult

Sexually transmitted diseases (STDs) are the most common infectious diseases worldwide, with over 350 million new cases occurring each year, and have far-reaching health, social, and economic consequences. Failure to diagnose and treat STDs at an early stage may result in serious complications and sequelae. STDs are passed from person to person primarily by sexual contact and are classified into varied groups. Some cause mild, acute symptoms and some are life-threatening. They are caused by many different infectious organisms and are treated in different ways. Syphilis and gonorrhea are ancient afflictions. Now, however, Chlamydia is prevalent and has become the most common bacterial STD. Antimicrobial resistance of several sexually transmitted pathogens is increasing, rendering some regimens ineffective, adding to therapeutic problems. A standardized treatment protocol for STDs is recommended to ensure that all patients receive adequate treatment. Appropriate treatment of STDs is an important public health measure.
Chancroid ; Chlamydia ; Clinical Protocols ; Communicable Diseases ; Dietary Sucrose ; Gonorrhea ; Humans ; Public Health ; Sexually Transmitted Diseases ; Sexually Transmitted Diseases, Bacterial ; Syphilis

PURPOSE: Fitz-Hugh-Curtis (FHC) syndrome has been described as perihepatitis associated with pelvic inflammatory disease during surgery. Recently, on computerized tomography a linear enhancement of the liver capsule was detected in a patient with FHC syndrome. We studied to evaluate the clinical course of the disease. METHODS: Sixteen patients diagnosed with FHC syndrome from CT findings were retrospectively studied from April, 2006 to June, 2008. RESULTS: The mean age of the patients was 25.9 (19~35) years and mean duration of abdominal pain was 3.9 (1~14) days. The most common complaint was right upper quadrant area pain (11 cases, 68.8%). 12 patients showed leukocytosis and all the patients had elevated serum C-reative protein levels. All the patients had normal liver function. Among the 9 patients which had polymerase chain reaction test for sexually transmitted disease (Chlamydia trachomatis, Ureaplasma urealyticum, Neisseria gonorrheae, Mycoplasma hominis), all showed more than one positive results (Chlamydia trachomatis 6 cases, Ureaplasma urealyticum 6 cases, Mycoplasma hominis 2 cases). On simple abdomen X-ray, 7 cases (43.8%) showed paralytic ileus. 14 cases received only antibiotic treatment, but 1 case had to take operation (laparoscopic-assisted adhesiolysis) due to constant abdominal pain and prolonged ileus. CONCLUSION: It is important to rule out FHC syndrome by using CT findings, especially young women with right upper abdominal pain and PID. Usually, FHC syndrome can be treated easily with proper antibiotics.
Abdomen ; Abdominal Pain ; Anti-Bacterial Agents ; Chlamydia Infections ; Female ; Gonorrhea ; Hepatitis ; Humans ; Ileus ; Intestinal Pseudo-Obstruction ; Leukocytosis ; Liver ; Mycoplasma ; Mycoplasma hominis ; Neisseria ; Pelvic Inflammatory Disease ; Peritonitis ; Polymerase Chain Reaction ; Retrospective Studies ; Sexually Transmitted Diseases ; Ureaplasma urealyticum

BACKGROUNDPrevious studies have shown evidence of health-related risk behaviors among women who have sex with women (WSW), such as sex with men, multiple bisexual partners, and drug use. Women who have sex with women have also been known to avoid routine physical examinations and conceal their same-sex history from physicians, which can affect their ability to receive an accurate diagnosis and treatment. No previous research has targeted women who have sex with women in China. We sought to describe women who have sex with women in China and explore risk factors for their reproductive tract infections (RTI)/sexually transmitted infections (STI).

METHODSParticipants were recruited through outreach in venues and online for a cross-sectional study. Data were collected using interviews and laboratory tests.

RESULTSWe recruited 224 women who have sex with women. In the year preceding their participation in the study, 92% (206/224) of women reported sexual relations with women. The RTI rates were: gonorrhea (15.8%), chlamydia (3.5%), syphilis (0.5%), bacterial vaginosis (14.4%), hepatitis B virus (HBV) (0.9%), hepatitis C virus (HCV) (0.5%), and candidiasis (6.9%). No HIV or herpes simplex virus (HSV) positive cases were detected. Factors associated with gonorrhea infection were non-Beijing local residency (odds ratio (OR) = 2.1, 95% confidence interval (CI): 1.2 - 3.8) and genital-genital contact (OR = 3.1, 95%CI: 1.3 - 7.2); factors associated with curable STI (excluding bacterial vaginosis, candidiasis, HBV and HCV) were non-Beijing local residency (OR = 1.9; 95%CI: 1.2 - 3.0) and bleeding during or after sex (OR = 18.1; 95%CI: 5.2 - 62.6); and the factor associated with RTI (including all the infections tested) was bleeding during or after sex (OR = 37.8, 95%CI: 11.2 - 127.4).

CONCLUSIONSBehaviors that may cause RTI/STI exist among Chinese women who have sex with women. Researchers should consider these behaviors when planning corresponding prevention and interventions.

Adult ; Candidiasis ; epidemiology ; China ; Female ; Gonorrhea ; epidemiology ; Hepatitis B ; epidemiology ; Hepatitis C ; epidemiology ; Homosexuality, Female ; statistics & numerical data ; Humans ; Risk Factors ; Sexually Transmitted Diseases ; epidemiology ; Syphilis ; epidemiology ; Vaginosis, Bacterial ; epidemiology ; Young Adult

OBJECTIVETo survey the prevalence of sexually transmitted diseases among high-risk population in Nanjing.

METHODSA high-risk population of 1539 underwent physical examinations from September 2001 to May 2004. The results were recorded, the urogenital swabs collected to further detect Neisseria gonorrhoeae (GN), Chlamydia trachomatis (Ct), Ureaplasma urealyticum (Uu), and the blood specimens tested for syphilis and HIV antibodies.

RESULTSThe infection rates were 13.5% for GN, 10.3% for syphilis, 2.3% for condyloma acuminata, 35.9% for Ct and 22.4% for Uu respectively. Nongonococcal urethritis (NUG) was shown to be the most prevalent STD in the group. No subject was found to be positive with HIV antibody.

CONCLUSIONScreening strategy in the high risk population is useful and efficient in controlling the spread of STDs and HIV.

Adolescent ; Adult ; Antibodies, Bacterial ; blood ; Antibodies, Viral ; blood ; China ; epidemiology ; Female ; Gonorrhea ; epidemiology ; HIV ; immunology ; HIV Infections ; epidemiology ; Humans ; Incidence ; Male ; Middle Aged ; Neisseria ; immunology ; Sexually Transmitted Diseases ; epidemiology ; Syphilis ; epidemiology ; Treponema ; immunology

BACKGROUND: Gonorrhea is one of the most common venereal diseases in the world. Antibioticresistance development has been an issue with the penicillinase-producing Neisseria gonorrhoeae(PPNG) development. It is possible for PPNG to be resistant to other medications. Therefore, it is significant to determine its frequency rate and its disposition. OBJECTIVES: In this surveillance, we examined overall development frequency of PPNG from 1981 ti 1998. Comparing current five years' frequency rate with that of previous five year, we predicted possible development rate and described the procedures the physicians must take into account in gonorrhea treatment. METHODS: We examined the development frequency of PPNG in male patients of the venereal disease clinic of Jung-gu Community Health Center in Seoul from 1981 to 1998. Also, we analyzed the overall tendency with time series analysis using statistics package, SPSS 7.5.Grouping the years in five-year units, development frequency of PPNG of current five years (1994-1998) was compared with that of previous years. RESULTS: For the result of monthly analysis of frequency rate of PPNG development from 1981 to 1998, the rate tendency came out with a sligh rise (slope : 0.15). And for the result of comparison of grouped years, in current five years, its rate was 51.6%, marking a significant decline from that of the previous five years, which was 57.2% (p-value : <0.0001). CONCLUSION: The rate of current five years was reported to have declined from the previous years. However, the rate is still over 50%. Therefore, the government should continue the PPNG surveillance with test of sensitivity of the medications in use. Moreover, to eliminate gonorrhea, the education on high risk groups should continue and physicians should use a dose of adequate antibiotics in treatment.
Anti-Bacterial Agents ; Community Health Centers* ; Education ; Gonorrhea ; Humans ; Male ; Neisseria gonorrhoeae* ; Neisseria* ; Seoul* ; Sexually Transmitted Diseases

INTRODUCTION: Secondary syphilis is a sexually transmitted infection characterized by localized or diffuse mucocutaneous lesions, often with generalized lymphadenopathy with laboratory evidence consistent with syphilis. Condolyma latum is one of the many forms of secondary syphilis and is noted to occur commonly on moist intertriginous areas of the body such as the axilla, web spaces of the toes, genital and perianal regions.
CASE REPORT: An 18 year-old man presented with a four-month history of few erythematous pruritic plaques on the penile shaft and multiple moist plaques involving the scalp, face, anterior neck, nape, axilla,anterior abdomen, upper and lower extremities, and scrotum. There are few erythematous scaly patches noted on the palms and soles. Serologic testing confirmed a diagnosis of syphilis and the patient tested negative for human immunodeficiency virus infection. The patient was given a single dose of intramuscular benzathine penicillin G 2.4 million units, with noted flattening of all lesions upon follow-up three months later.
CONCLUSION: Condylomata lata, although most commonly found on moist intriginous areas of the axilla, web spaces of the toes, genital and perianal regions, can also involve less commonly affected areas such as the scalp, face, anterior abdomen, and the extremities. A high index of suspicion therefore is warranted to differentiate it from other cutaneous diseases and to prevent progression of the disease by initiating appropriate antibacterial therapy.

Human ; Male ; Adolescent ; Anti-bacterial Agents ; Axilla ; Hiv Infections ; Lower Extremity ; Lymphadenopathy ; Scrotum ; Sexually Transmitted Diseases ; Syphilis ; Syphilis, Cutaneous

Following the Korean War, presence of foreign troops in Korea, economic difficulty and changing moral Standards have brought about the development of concentrations of prostitutes around army camps known as "villes". The problems with venereal disease among the prostitutes living in the villes and consequently among soldiers has been a problem which has perplexed both American and Korean health authorities. Research into the problems and efforts to solve the V.D. problem have yielded only fragmentary results. Fortunately, with the cooperation of the U.S. Army Research and Development Group, an extensive research project has been undertaken to determine the root causes and best methods to prevent venereal disease in the villes around American military installations. The villes around large military installations were selected as the target of this research. In particular, the Pyeongtaek ville, the Gunsan "Silver Town" area and the "Texas Town" area of Busan were studied. The study took two years, from April, 1973 to March, 1975. Microbiological and serological studies were undertaken to determine the venereal disease infection rate and the efficacy of different antibiotics both in treatment and in sensitivity tests. In addition to the microbiological and serological studies other factors related to venereal diseases control such as social environment, health facilities, knowledge of venereal disease and its control were studied. The following results were obtained. 1. An overall gonorrheal morbidity rate of 14.1% was found among the 1,282 girls studied. This shows e rather dramatic rise compared to other studies. The majority of the increase is attributed to an actual increase of the V.D. rate, but more precise methods of isolation and culture using Thayer-Martin media also contributed to the increase recorded. 2. In Pyeongtaek, a gonorrhea morbidity rate of 5.39/0 (endocervical), the lowest in any of the villes was recorded. The Pyeongtaek police of enforced hospitalization until cure was effected tended to eliminate contact with infected girls and also make the girls more aware of and concerned about prevention of venereal disease. The Texas town prostitutes in Busan had a 15.5% (endocervical) morbidity rate, the highest of any of the areas. This might be attributed to sexual contact with many foreign sailors. 3. In culturing for gonorrhea, it was found that rectal as well as cervical cultures are necessary. Rectal cultures revealed 71 cases(39.2% to total positive cases) some of which were negative by endocervical culture, and endocervical cultures yielded 181 positives among the 1,282 cases surveyed. 4. A total of 988 serological tests for syphilis were carried out. By the V.D.R.L. method, 11.5% reactive cases were recorded, Kolmer C-F showed 5.9% reactive and RPCF test showed a 4.3% reactive rate. The RPR card test was used to retest 151 persons who were demonstrated to be V.D.R.L. (in prostitutes and general entertainers) reactive and confirmatory reactive results were shown in 74.0% of the cases. The FTA-ABS test was done on 57 RPCF tes/; reactive cases and showed confirmatory reactive results in 96.5% of the cases. It was concluded that the RPR card test, although it is less sensitive than the V.D.R.L test was both simple and effective for use in mass screening. However it is suggested that RPR card test rectors be reconfirmed using either the RPCF test or the FTA-ABS test. 5. Penicillin treatment failed to cure 40% of the gonorrhea patients in clinical tests and 16% of the strains used in the sensitivity tests showed resistance to penicillin. Therefore, penicillin was judged to be rather ineffective against gonorrhea. Ampicillin, however, is still quite effective, and spectinomycin was the most effective antibiotic against gonorrhea. 6. The socio-medical study of prostitutes revealed that their average age 25.5 years and the average number of years of education was 6. 8, implying the completion of primary school. Living conditions were generally poor, for example, in Pyeongtaek, 37% of the girls did not have running water and depended on well water. Data on the toilet facilities revealed that 78% of the prostitutes living in the control area in Wanweoldong, Busan were still using traditional Korean privy style toilets, and in Pyeongtaek 91% also were using privy toilets. Over two-thirds of the prostitutes only bathed once or twice a week. Therefore, improvement of living conditions was considered a critical problem. 7. Generally speaking, the girls had some know/edge of syphilis and gonorrhea and the measures necessary to prevent these diseases. However, over half of the girls abused antibiotics in venereal disease treatment and prevention attempts and only 65% of them required their partner to use a condom. Therefore, much improvement is needed in this area. 8. A survey of knowledge about contraceptive measures showed that 96% of the girls had good knowledge about oral contraceptives, 90 knew about condoms and 88% had knowledge of the douche method. In actual practice however, 95% of the girls used the douche method and 62% used condoms for contraception.
Ampicillin ; Anti-Bacterial Agents ; Baths ; Busan ; Condoms ; Contraception ; Contraceptives, Oral ; Education ; Female ; Fluorescent Treponemal Antibody-Absorption Test ; Gonorrhea ; Gyeonggi-do ; Health Facilities ; Hospitalization ; Humans ; Jeollabuk-do ; Korea* ; Korean War ; Mass Screening ; Military Personnel ; Penicillins ; Police ; Running ; Serologic Tests ; Sex Workers* ; Sexually Transmitted Diseases* ; Social Conditions ; Social Environment ; Spectinomycin ; Syphilis ; Texas ; Toilet Facilities

Background: Bacterial vaginosis is a very common vaginal infection. It occurs when bacteria that normally exist in small numbers in the vagina multiply rapidly. With the purpose of early diagnosis and timely treatment infection of vaginalis tract. Objectives: The study was conducted with 2 purposes: Firstly, identification of bacterial and fungical causa is of the vaginalis. Secondly, comparison of the cause among 2 groups of women with clinical symptoms and group came for health examination. Subjects and method:A cross-sectional study was carried out in sampled groups: 325 women with ginecological symptom and 385 women came for health examination at the clinic of the Institute of mother and Newborn protection. Both 2 groups were clinical examined and microbiological testing. Results: The results were showed: The prevalence of vaginalis of the group with ginecological symptoms was found 76.92% and in the other group was 56.1%. The was not any disparity in clinical and testing results. The microbiological causes were found: 22.15% candida in group with clinical symptom and 18.96% in the other group. Streptococcal group D was taken second place 20.61% in group with clinical symptom and 13.25%in group with health examination and folioing are S. aureus, E.coli, C.trachomatis, G.vaginalis. Conclusion: There\u2019s no significant difference in the prevalence of infection of vaginalis tract between some age groups in this study.
Sexually Transmitted Diseases ; Bacterial/ pathology Female

PURPOSE: To report a patient with ocular syphilis, who showed variable ocular manifestations, including optic neuritis and chorioretinitis in both eyes over a short time period. CASE SUMMARY: A 44-year-male visited our clinic for central scotoma in the left eye. The visual acuity was 20/25 in the right eye and 20/40 in the left eye. The fundus of the left eye showed a slightly hyperemic optic disc and multiple yellowish deposits. One week later, visual acuity and fundus lesion improved to 20/20 without a definitive treatment. However, 1 month later, he reported a new deterioration of vision in his right eye to 20/40. The right eye had a relative afferent pupillary defect and the fundus examination showed a blurred optic disc margin. Serological work-up was recommended but the patient refused. He returned 3 weeks later with an improvement in the right eye vision (20/25) and a worsening in the left eye (20/200). The examination revealed an improvement of the previously blurred disc margin in the right eye and newly developed chorioretinitis with vasculitis in the left eye. A serological test was performed. The venereal diseases research laboratory titer was 1:32. The fluorescent treponemal antigen absorbance test as positive for IgG and IgM. He was diagnosed with ocular syphilis and referred to the infectious disease department. He was treated with antibiotics. Six months later, the visual acuity was 20/20 in both eyes and the previous fundus lesions had disappeared. CONCLUSIONS: Ocular syphilis should be considered in patients with atypical and variable clinical course.
Anti-Bacterial Agents ; Chorioretinitis* ; Communicable Diseases ; Humans ; Immunoglobulin G ; Immunoglobulin M ; Optic Neuritis* ; Pupil Disorders ; Scotoma ; Serologic Tests ; Sexually Transmitted Diseases ; Syphilis* ; Vasculitis ; Visual Acuity