OBJECTIVE: This study aimed to examine the associations between depression and both coronary artery disease (CAD) and cardiovascular risk factors (CVRs) in Korean women. Furthermore, this study sought to determine whether depression was associated with use of healthcare services in women with CAD or CVRs. METHODS: This cross-sectional study was conducted on 26,335 women who were aged 19 years or older, and who participated in the Korean National Health and Nutrition Examination Survey (2007–2014). Associations of prior diagnosis of depression with CAD and CVRs and with nonutilization of healthcare services were investigated. RESULTS: Women with depression had a higher prevalence of CAD and CVRs including obesity, hypertension, dyslipidemia, and metabolic syndrome than those without depression. In addition, depression was significantly associated with nonutilization of healthcare services in women with most CVRs. CONCLUSION: Considering the high rate of comorbid depression with CAD or CVRs and the low lvels of health service utilization in depressed patients, screening for common CVRs, such as obesity, hypertension, and dyslipidemia, should be provided for patients with depression in mental health care settings.
Coronary Artery Disease ; Cross-Sectional Studies ; Delivery of Health Care* ; Depression* ; Diagnosis ; Dyslipidemias ; Female ; Health Services ; Humans ; Hypertension ; Mass Screening ; Mental Health ; Nutrition Surveys ; Obesity ; Prevalence ; Risk Factors

OBJECTIVE: Previous neuroimaging studies on romantic love have focused on determining how the visual stimuli that serve as a representation of loved ones induce the neural activation patterns of romantic love. The purpose of this study was to investigate the temporal changes in romantic love over a period of 6 months and their correlated neurophysiological changes. METHODS: Five heterosexual couples (n=10, mean age 21.1+/-1.97) who started dating not less than 100 days previously were recruited to measure their blood oxygen level dependent (BOLD) signals using functional magnetic resonance imaging (fMRI) while showing them pictures of their loved ones and their previously identified, opposite-sex friends. Subsequently, the subjects were scanned under the same experimental conditions to assess possible changes in their brain activities after 180 days. RESULTS: We found that their Passionate Love Score (PLS) values (M: 118.6+/-9.1, F: 120.2+/-7.0) were significantly reduced after 6 months (M: 110.8+/-4.0, F: 106.2+/-3.0). Furthermore, significantly increased activations were found in the cingulate gyri, inferior frontal gyri, supramarginal gyri, etc., after 6 months, whereas the head and tail of the right caudate nucleus were deactivated, which is indicative of the inhibition of expression and sensory neglect. CONCLUSION: These findings suggest that dynamic neural processes in the cortical-subcortical regions are involved in temporal changes in romantic love.
Brain ; Caudate Nucleus ; Family Characteristics ; Friends ; Head ; Heterosexuality ; Humans ; Love ; Magnetic Resonance Imaging ; Magnetic Resonance Spectroscopy ; Magnetics ; Magnets ; Neuroimaging ; Oxygen ; Perceptual Disorders

OBJECTIVE: People with depression often suffer from comorbid, chronic physical diseases. Little is known about how demographic characteristics such as age and sex influence the prevalence of chronic physical diseases comorbid with depression. Therefore, this study aimed to explore the age and sex differences in the prevalence of diverse, chronic physical diseases comorbid with depression. METHODS: This cross-sectional survey were conducted with the participants (n=45,598) of the Korean National Health and Nutrition Examination Survey (KNHANES). Using log-binomial regression, age adjusted prevalence ratios (APR) of chronic physical diseases of participants with depression and those without depression were estimated for each sex and age group. RESULTS: The APR of most chronic physical diseases were significantly higher among respondents with depression than those without depression. Chronic physical diseases that showed the highest APR were asthma in adult male respondents (APR=3.46) and adult female respondents (APR=2.19) and chronic renal failure in elderly male respondents (APR=8.36) and elderly female respondents (APR=1.94). CONCLUSION: Prevalence ratios of the chronic physical diseases comorbid with depression differed according to sex and age groups. Collaborative care strategies should be designed according to demographic characteristics of the population.
Adult ; Aged ; Asthma ; Comorbidity ; Cross-Sectional Studies ; Depression* ; Female ; Humans ; Kidney Failure, Chronic ; Korea* ; Male ; Nutrition Surveys ; Prevalence* ; Sex Characteristics ; Surveys and Questionnaires