1.Investigating Disembodiment-related Brain Activation by Interaction between Perspective-shifting and the Experience of Agency in Autism Spectrum Disorder: A Possible Relationship with Interoceptive Abilities
Ahjeong HUR ; Seungwon CHUNG ; Huiyeong JEON ; Hoyeon LEE ; Yong-Wook SHIN ; Jung-Woo SON
Clinical Psychopharmacology and Neuroscience 2025;23(1):86-99
Objective:
Many studies have explored sense of self in individuals with autism spectrum disorder (ASD); however, few have reported on their experience of “disembodiment.” This study aimed to investigate the differences in brain activity between patients with ASD and neurotypicals (NTs) under conditions causing disembodiment and to examine the correlation between their interoceptive abilities and disembodiment-related brain activity.
Methods:
18 Participants with ASD and 21 NTs completed psychological evaluations, interoceptive abilities measurement, and functional magnetic resonance imaging (fMRI). The fMRI images were taken while the participants performed tasks involving ball-throwing animations. The task focused on either self-agency related to ball-throwing (Agency Task) or the spatial location of a ball (Location Task). The animations were presented from constantly changing perspective (Changing View) or fixed perspective (Fixed View). The disembodiment-related condition was the interaction between the Agency Task and Changing View.
Results:
Participants with ASD exhibited higher activation than NTs in regions near the left parieto-temporo-occipital junction, left precuneus, left hippocampus, and other brain areas. Furthermore, interoceptive accuracy was negatively correlated with the activity of the left superior parietal and posterior midcingulate areas, whereas interoceptive trait prediction error was positively correlated with the activity of the left hippocampus, mid-temporal area, and left posterior cingulate area in participants with ASD.
Conclusion
These results suggest that disembodiment-related brain activation might be easily manifested by the interaction between perspective-shifting and the experience of agency, and that interoceptive abilities might be related to disembodiment-related brain activation in individuals with ASD.
2.Investigating Disembodiment-related Brain Activation by Interaction between Perspective-shifting and the Experience of Agency in Autism Spectrum Disorder: A Possible Relationship with Interoceptive Abilities
Ahjeong HUR ; Seungwon CHUNG ; Huiyeong JEON ; Hoyeon LEE ; Yong-Wook SHIN ; Jung-Woo SON
Clinical Psychopharmacology and Neuroscience 2025;23(1):86-99
Objective:
Many studies have explored sense of self in individuals with autism spectrum disorder (ASD); however, few have reported on their experience of “disembodiment.” This study aimed to investigate the differences in brain activity between patients with ASD and neurotypicals (NTs) under conditions causing disembodiment and to examine the correlation between their interoceptive abilities and disembodiment-related brain activity.
Methods:
18 Participants with ASD and 21 NTs completed psychological evaluations, interoceptive abilities measurement, and functional magnetic resonance imaging (fMRI). The fMRI images were taken while the participants performed tasks involving ball-throwing animations. The task focused on either self-agency related to ball-throwing (Agency Task) or the spatial location of a ball (Location Task). The animations were presented from constantly changing perspective (Changing View) or fixed perspective (Fixed View). The disembodiment-related condition was the interaction between the Agency Task and Changing View.
Results:
Participants with ASD exhibited higher activation than NTs in regions near the left parieto-temporo-occipital junction, left precuneus, left hippocampus, and other brain areas. Furthermore, interoceptive accuracy was negatively correlated with the activity of the left superior parietal and posterior midcingulate areas, whereas interoceptive trait prediction error was positively correlated with the activity of the left hippocampus, mid-temporal area, and left posterior cingulate area in participants with ASD.
Conclusion
These results suggest that disembodiment-related brain activation might be easily manifested by the interaction between perspective-shifting and the experience of agency, and that interoceptive abilities might be related to disembodiment-related brain activation in individuals with ASD.
3.Investigating Disembodiment-related Brain Activation by Interaction between Perspective-shifting and the Experience of Agency in Autism Spectrum Disorder: A Possible Relationship with Interoceptive Abilities
Ahjeong HUR ; Seungwon CHUNG ; Huiyeong JEON ; Hoyeon LEE ; Yong-Wook SHIN ; Jung-Woo SON
Clinical Psychopharmacology and Neuroscience 2025;23(1):86-99
Objective:
Many studies have explored sense of self in individuals with autism spectrum disorder (ASD); however, few have reported on their experience of “disembodiment.” This study aimed to investigate the differences in brain activity between patients with ASD and neurotypicals (NTs) under conditions causing disembodiment and to examine the correlation between their interoceptive abilities and disembodiment-related brain activity.
Methods:
18 Participants with ASD and 21 NTs completed psychological evaluations, interoceptive abilities measurement, and functional magnetic resonance imaging (fMRI). The fMRI images were taken while the participants performed tasks involving ball-throwing animations. The task focused on either self-agency related to ball-throwing (Agency Task) or the spatial location of a ball (Location Task). The animations were presented from constantly changing perspective (Changing View) or fixed perspective (Fixed View). The disembodiment-related condition was the interaction between the Agency Task and Changing View.
Results:
Participants with ASD exhibited higher activation than NTs in regions near the left parieto-temporo-occipital junction, left precuneus, left hippocampus, and other brain areas. Furthermore, interoceptive accuracy was negatively correlated with the activity of the left superior parietal and posterior midcingulate areas, whereas interoceptive trait prediction error was positively correlated with the activity of the left hippocampus, mid-temporal area, and left posterior cingulate area in participants with ASD.
Conclusion
These results suggest that disembodiment-related brain activation might be easily manifested by the interaction between perspective-shifting and the experience of agency, and that interoceptive abilities might be related to disembodiment-related brain activation in individuals with ASD.
4.Investigating Disembodiment-related Brain Activation by Interaction between Perspective-shifting and the Experience of Agency in Autism Spectrum Disorder: A Possible Relationship with Interoceptive Abilities
Ahjeong HUR ; Seungwon CHUNG ; Huiyeong JEON ; Hoyeon LEE ; Yong-Wook SHIN ; Jung-Woo SON
Clinical Psychopharmacology and Neuroscience 2025;23(1):86-99
Objective:
Many studies have explored sense of self in individuals with autism spectrum disorder (ASD); however, few have reported on their experience of “disembodiment.” This study aimed to investigate the differences in brain activity between patients with ASD and neurotypicals (NTs) under conditions causing disembodiment and to examine the correlation between their interoceptive abilities and disembodiment-related brain activity.
Methods:
18 Participants with ASD and 21 NTs completed psychological evaluations, interoceptive abilities measurement, and functional magnetic resonance imaging (fMRI). The fMRI images were taken while the participants performed tasks involving ball-throwing animations. The task focused on either self-agency related to ball-throwing (Agency Task) or the spatial location of a ball (Location Task). The animations were presented from constantly changing perspective (Changing View) or fixed perspective (Fixed View). The disembodiment-related condition was the interaction between the Agency Task and Changing View.
Results:
Participants with ASD exhibited higher activation than NTs in regions near the left parieto-temporo-occipital junction, left precuneus, left hippocampus, and other brain areas. Furthermore, interoceptive accuracy was negatively correlated with the activity of the left superior parietal and posterior midcingulate areas, whereas interoceptive trait prediction error was positively correlated with the activity of the left hippocampus, mid-temporal area, and left posterior cingulate area in participants with ASD.
Conclusion
These results suggest that disembodiment-related brain activation might be easily manifested by the interaction between perspective-shifting and the experience of agency, and that interoceptive abilities might be related to disembodiment-related brain activation in individuals with ASD.
5.Effectiveness Analysis of School-Based Self-Harm Prevention Program for Children and Adolescent Using Brief Dialectical Behavior Therapy Skills Training: Based on Age, Sex, Self-Harm History and Program Implementation Methods
Je Jung LEE ; Cheolgyu SHIN ; Hyunjeong KIM ; Sunkyu PARK ; Inyoung NOH ; Jonggook LEE ; Keun OH ; Heeyoung SEO ; Seungwon CHUNG
Korean Journal of Psychosomatic Medicine 2024;32(2):87-97
Objectives:
:This study aims to confirm the effectiveness of a school-based very-short-term dialectical be-havior therapy-skills training (DBT-ST) program for preventing self-harm among children and adolescents, considering factors such as age, sex, self-harm history, and methods of program implementation.
Methods:
:The study was conducted from September 2021 to December 2023, targeting 1,012 elementary and middle school students in the Chungcheong region. Changes in responses to the Depressed Mood Questionnaire(RDQ), the Difficulties in Emotion Regulation Scale-16 (DERS-16), ‘future self-harm possibility’ scores wereanalyzed and compared before and after the program, based on age, sex, self-harm history, and methods of program implementation.
Results:
:Overall, participants showed a decrease in the ‘rumination(RDQ) scale’ (t=10.49, p<0.001), ‘reversescored distraction (RDQ)’ (t=10.67, p<0.001) and the total DERS-16 (t=5.56, p<0.001) as well as a decrease in ‘future self-harm possibility’ score (t=4.26, p<0.001). Both elementary and middle school students showed decrease in ’rumination (RDQ)’ and distraction (RDQ), but only middle school students showed a decrease in theDERS-16 and most sub-scales. Regardless of sex, self-harm history, or methods of program implementation, adecrease in ’rumination (RDQ)’, distraction (RDQ) and the total DERS-16 scale and most sub-scales decreased.
Conclusions
:Our program appears to be effective as a primary prevention program for preventing self-harm among children and adolescents in a school setting.
6.Effectiveness Analysis of School-Based Self-Harm Prevention Program for Children and Adolescent Using Brief Dialectical Behavior Therapy Skills Training: Based on Age, Sex, Self-Harm History and Program Implementation Methods
Je Jung LEE ; Cheolgyu SHIN ; Hyunjeong KIM ; Sunkyu PARK ; Inyoung NOH ; Jonggook LEE ; Keun OH ; Heeyoung SEO ; Seungwon CHUNG
Korean Journal of Psychosomatic Medicine 2024;32(2):87-97
Objectives:
:This study aims to confirm the effectiveness of a school-based very-short-term dialectical be-havior therapy-skills training (DBT-ST) program for preventing self-harm among children and adolescents, considering factors such as age, sex, self-harm history, and methods of program implementation.
Methods:
:The study was conducted from September 2021 to December 2023, targeting 1,012 elementary and middle school students in the Chungcheong region. Changes in responses to the Depressed Mood Questionnaire(RDQ), the Difficulties in Emotion Regulation Scale-16 (DERS-16), ‘future self-harm possibility’ scores wereanalyzed and compared before and after the program, based on age, sex, self-harm history, and methods of program implementation.
Results:
:Overall, participants showed a decrease in the ‘rumination(RDQ) scale’ (t=10.49, p<0.001), ‘reversescored distraction (RDQ)’ (t=10.67, p<0.001) and the total DERS-16 (t=5.56, p<0.001) as well as a decrease in ‘future self-harm possibility’ score (t=4.26, p<0.001). Both elementary and middle school students showed decrease in ’rumination (RDQ)’ and distraction (RDQ), but only middle school students showed a decrease in theDERS-16 and most sub-scales. Regardless of sex, self-harm history, or methods of program implementation, adecrease in ’rumination (RDQ)’, distraction (RDQ) and the total DERS-16 scale and most sub-scales decreased.
Conclusions
:Our program appears to be effective as a primary prevention program for preventing self-harm among children and adolescents in a school setting.
7.Effectiveness Analysis of School-Based Self-Harm Prevention Program for Children and Adolescent Using Brief Dialectical Behavior Therapy Skills Training: Based on Age, Sex, Self-Harm History and Program Implementation Methods
Je Jung LEE ; Cheolgyu SHIN ; Hyunjeong KIM ; Sunkyu PARK ; Inyoung NOH ; Jonggook LEE ; Keun OH ; Heeyoung SEO ; Seungwon CHUNG
Korean Journal of Psychosomatic Medicine 2024;32(2):87-97
Objectives:
:This study aims to confirm the effectiveness of a school-based very-short-term dialectical be-havior therapy-skills training (DBT-ST) program for preventing self-harm among children and adolescents, considering factors such as age, sex, self-harm history, and methods of program implementation.
Methods:
:The study was conducted from September 2021 to December 2023, targeting 1,012 elementary and middle school students in the Chungcheong region. Changes in responses to the Depressed Mood Questionnaire(RDQ), the Difficulties in Emotion Regulation Scale-16 (DERS-16), ‘future self-harm possibility’ scores wereanalyzed and compared before and after the program, based on age, sex, self-harm history, and methods of program implementation.
Results:
:Overall, participants showed a decrease in the ‘rumination(RDQ) scale’ (t=10.49, p<0.001), ‘reversescored distraction (RDQ)’ (t=10.67, p<0.001) and the total DERS-16 (t=5.56, p<0.001) as well as a decrease in ‘future self-harm possibility’ score (t=4.26, p<0.001). Both elementary and middle school students showed decrease in ’rumination (RDQ)’ and distraction (RDQ), but only middle school students showed a decrease in theDERS-16 and most sub-scales. Regardless of sex, self-harm history, or methods of program implementation, adecrease in ’rumination (RDQ)’, distraction (RDQ) and the total DERS-16 scale and most sub-scales decreased.
Conclusions
:Our program appears to be effective as a primary prevention program for preventing self-harm among children and adolescents in a school setting.
8.Effectiveness Analysis of School-Based Self-Harm Prevention Program for Children and Adolescent Using Brief Dialectical Behavior Therapy Skills Training: Based on Age, Sex, Self-Harm History and Program Implementation Methods
Je Jung LEE ; Cheolgyu SHIN ; Hyunjeong KIM ; Sunkyu PARK ; Inyoung NOH ; Jonggook LEE ; Keun OH ; Heeyoung SEO ; Seungwon CHUNG
Korean Journal of Psychosomatic Medicine 2024;32(2):87-97
Objectives:
:This study aims to confirm the effectiveness of a school-based very-short-term dialectical be-havior therapy-skills training (DBT-ST) program for preventing self-harm among children and adolescents, considering factors such as age, sex, self-harm history, and methods of program implementation.
Methods:
:The study was conducted from September 2021 to December 2023, targeting 1,012 elementary and middle school students in the Chungcheong region. Changes in responses to the Depressed Mood Questionnaire(RDQ), the Difficulties in Emotion Regulation Scale-16 (DERS-16), ‘future self-harm possibility’ scores wereanalyzed and compared before and after the program, based on age, sex, self-harm history, and methods of program implementation.
Results:
:Overall, participants showed a decrease in the ‘rumination(RDQ) scale’ (t=10.49, p<0.001), ‘reversescored distraction (RDQ)’ (t=10.67, p<0.001) and the total DERS-16 (t=5.56, p<0.001) as well as a decrease in ‘future self-harm possibility’ score (t=4.26, p<0.001). Both elementary and middle school students showed decrease in ’rumination (RDQ)’ and distraction (RDQ), but only middle school students showed a decrease in theDERS-16 and most sub-scales. Regardless of sex, self-harm history, or methods of program implementation, adecrease in ’rumination (RDQ)’, distraction (RDQ) and the total DERS-16 scale and most sub-scales decreased.
Conclusions
:Our program appears to be effective as a primary prevention program for preventing self-harm among children and adolescents in a school setting.
9.Effectiveness Analysis of School-Based Self-Harm Prevention Program for Children and Adolescent Using Brief Dialectical Behavior Therapy Skills Training: Based on Age, Sex, Self-Harm History and Program Implementation Methods
Je Jung LEE ; Cheolgyu SHIN ; Hyunjeong KIM ; Sunkyu PARK ; Inyoung NOH ; Jonggook LEE ; Keun OH ; Heeyoung SEO ; Seungwon CHUNG
Korean Journal of Psychosomatic Medicine 2024;32(2):87-97
Objectives:
:This study aims to confirm the effectiveness of a school-based very-short-term dialectical be-havior therapy-skills training (DBT-ST) program for preventing self-harm among children and adolescents, considering factors such as age, sex, self-harm history, and methods of program implementation.
Methods:
:The study was conducted from September 2021 to December 2023, targeting 1,012 elementary and middle school students in the Chungcheong region. Changes in responses to the Depressed Mood Questionnaire(RDQ), the Difficulties in Emotion Regulation Scale-16 (DERS-16), ‘future self-harm possibility’ scores wereanalyzed and compared before and after the program, based on age, sex, self-harm history, and methods of program implementation.
Results:
:Overall, participants showed a decrease in the ‘rumination(RDQ) scale’ (t=10.49, p<0.001), ‘reversescored distraction (RDQ)’ (t=10.67, p<0.001) and the total DERS-16 (t=5.56, p<0.001) as well as a decrease in ‘future self-harm possibility’ score (t=4.26, p<0.001). Both elementary and middle school students showed decrease in ’rumination (RDQ)’ and distraction (RDQ), but only middle school students showed a decrease in theDERS-16 and most sub-scales. Regardless of sex, self-harm history, or methods of program implementation, adecrease in ’rumination (RDQ)’, distraction (RDQ) and the total DERS-16 scale and most sub-scales decreased.
Conclusions
:Our program appears to be effective as a primary prevention program for preventing self-harm among children and adolescents in a school setting.
10.Comparing Ruminative and Distracting Responses and Emotion Regulation Difficulties in Early Community Adolescents With and Without Self-Harm
Yeontaek OH ; Cheolgyu SHIN ; Jonggook LEE ; Keun OH ; Heeyoung SEO ; Seungwon CHUNG ; Je Jung LEE
Journal of the Korean Academy of Child and Adolescent Psychiatry 2024;35(2):127-135
Objectives:
This study aimed to compare the demographic characteristics, responses to negative emotions, and difficulties in emotion regulation between self-harming adolescents and control individuals aged 12–14 years from the community.
Methods:
Data were collected from adolescents in Chungcheong Province, South Korea, between September 2021 and November 2022.Demographic characteristics and responses to the Depressed Mood Questionnaire and Difficulties in Emotion Regulation Scale-16 (DERS-16) were compared between the self-harm and control groups.
Results:
The self-harm group exhibited a higher prevalence of child abuse (odds ratio [OR]=4.787, 95% confidence interval [CI]=1.591– 14.409, p=0.005) and school bullying victimization (OR=4.495, 95% CI=2.353–8.588, p<0.001) than those in the control group. The selfharm group displayed higher levels of rumination (t=7.88, p<0.001) and reduced distraction responses (reverse score t=2.25, p=0.025) than those of the control group. Additionally, the self-harm group scored higher on all subscales and the total DERS-16 score (t=7.61, p<0.001).
Conclusion
Interventions for self-harming adolescents should address child abuse and bullying victimization. Prevention programs for self-harming adolescents should focus on reducing rumination responses, increasing distractive responses, and addressing difficulties in emotion regulation using dialectical behavior therapy-skill training.

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