1.Vitamin D Levels in Patients with Low-energy Hip Fractures
Jaehwi HAN ; Youngho CHO ; Seungmin JEE ; Seongwoo JO
Hip & Pelvis 2020;32(4):192-198
Purpose:
To evaluate serum 25(OH) vitamin D levels in patients with low-energy hip fractures.
Materials and Methods:
Among 983 patients who underwent hip fracture surgery between August 2013 and March 2019, 732 patients were evaluated. The remaining patients were excluded due to the presence of one or more of the following: metastatic bone tumor, metabolic bone disease other than osteoporosis, fracture due to high-energy injury, atypical femoral fracture, and no blood test. We collected patient’s data about age, sex male female, date of injury, a place of residence, fracture type, preinjury ambulation ability according to their Koval score, and their serum level of 25(OH) vitamin D. The mean age was 79.3 years (60-104 years). The sample was comprised of 530 female and 202 male, of which 342 had femoral neck fractures and 390 had trochanteric fractures.
Results:
Of the total 732 patients, 346 patients (47.3%) had a 25(OH) vitamin D level of less than 10 ng/mL, 264 patients (36.1%) had scores of 10-19.9 ng/mL, 87 patients (11.9%) had scores of 20-29.9 ng/mL, and 35 patients (4.8%) had a level higher than 30 ng/mL. Vitamin D deficiency (less than 20 ng/mL) was present in 610 patients (83.3%), insufficiency (20-29.9 ng/mL) was found in 87 patients (11.9%), and 35 patients (4.8%) had normal vitamin D levels. The differences in vitamin D concentration based on season and fracture type were statistically significant.
Conclusion
Vitamin D deficiency and inadequacy were high in patients with low-energy hip fractures, with only 4.9% of patients had normal vitamin D levels. These findings suggest that efforts should be made to maintain proper vitamin D concentration.
2.Motor and Sensory Peripheral Neuropathy in a Patient Came after Acute Carbon Monoxide Intoxication: a Case Report with Magnetic Resonance Image.
Seungmin LEE ; Sang Yoon KIM ; Jee Young LEE ; Min Jeong CHOI
Investigative Magnetic Resonance Imaging 2016;20(3):175-180
Carbon monoxide (CO) intoxication is a leading cause of the variable neuropsychiatric impairment. Despite of widely known central nerve system complications after CO intoxication, peripheral neuropathy due to CO poisoning is rare and has been under-recognized. We report interesting case of a 29-year-old male who suffered from motor weakness and sensory abnormalities in his lower extremity following acute CO intoxication. The patient revealed direct and indirect signs of peripheral neuropathy of the left inferior gluteal and sciatic nerve on magnetic resonance imaging.
Adult
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Carbon Monoxide*
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Carbon*
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Humans
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Lower Extremity
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Magnetic Resonance Imaging
;
Male
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Peripheral Nervous System Diseases*
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Poisoning
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Sciatic Nerve
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Sciatic Neuropathy
3.An Unusual Case of Spontaneous Remission of Hodgkin's Disease after a Single Cycle of COPP-ABV Chemotherapy Followed by Infectious Complications.
Seungmin BANG ; June Won CHEONG ; Woo Ick YANG ; Jee Sook HAHN
Yonsei Medical Journal 2005;46(3):425-430
Advanced Hodgkin's disease is usually treated with six or more cycles of combination chemotherapy. Spontaneous regression of the cancer is very rarely reported in patients with Hodgkin's disease. We present an unusual case of a patient with Hodgkin's disease who experienced complete remission with a single cycle of chemotherapy, followed by pneumonia. The case was a 36-year-old man diagnosed with stage IVB mixed cellularity Hodgkin's disease in November 2000. After treatment with one cycle of COPP-ABV (cyclophosphamide, vincristine, procarbazine, prednisone, doxorubicin, bleomycin, and vinblastine) chemotherapy without bleomycin, the patient developed interstitial pneumonia and was cared in the intensive care unit (ICU) for two months. Follow-up chest computerized tomography (CT), performed during the course of ICU care, revealed markedly improved mediastinal lymphomatous lesions. Furthermore, follow-up whole body CT and 18-fluorodeoxyglucose positron emission tomography showed complete disappearance of the lymphomatous lesions. Four years later, the patient is well and without relapse. This report is followed by a short review of the literature on spontaneous regression of Hodgkin's disease. To the best of our knowledge, this is the first case report of spontaneous remission of Hodgkin's disease in Korea.
Adult
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Antineoplastic Combined Chemotherapy Protocols/*administration & dosage
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Bleomycin/*administration & dosage
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Cyclophosphamide/*administration & dosage
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Doxorubicin/*administration & dosage
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Hodgkin Disease/*complications/*drug therapy
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Humans
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Male
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Pneumonia/*complications
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Prednisone/*administration & dosage
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Procarbazine/*administration & dosage
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Remission, Spontaneous
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Vinblastine/*administration & dosage
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Vincristine/*administration & dosage