1.A Literature Review on the Public Program of Walking Promotion for Active Living
Dong Ha KIM ; Jaewook KANG ; Seunghyun YOO
Journal of Agricultural Medicine & Community Health 2021;46(2):98-108
Objectives:
This study aimed to describe the current public programs for community walking in Korea and to discuss their challenges.Method: We identified the literature related to community walking including five laws, 22 white papers from government departments and 84 program reports from the Seoul Metropolitan Government.
Results:
Korean law guarantees legal rights and validity to create safe, convenient and equitable environments for community walking. The government department, which has jurisdiction over legislation relating to community walking, has dominated community walking programs, and the role of public health department has been insufficient. Almost all sectors in the department of Seoul Metropolitan Government were involved in community walking programs. However, inter-sectoral cooperation system for community walking was insufficient.
Conclusion
It is necessary to revise the condolences of the National Health Promotion Act to establish the role and perspective of public health in community walking promotion. Institutional efforts should be made to expand the network structure between sectors of community walking programs by establishing an organizational, budget, and performance sharing system for inter-sectoral approach.
2.Perioperative consideration of general anesthesia for acromegalic patients.
Seunghyun KANG ; Yong Hyun CHO ; Sun Hee KIM ; Dong Hyun LEE
Korean Journal of Anesthesiology 2014;67(Suppl):S83-S84
No abstract available.
Anesthesia, General*
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Humans
3.Hematocrit Determination using a Volumetric Absorptive Microsampling Technique in Patients with Pancreatic Cancer
Yeolmae JUNG ; Seunghyun YOO ; Minseo KANG ; Hayun LIM ; Myeong Hwan LEE ; Ji Kon RYU ; Jangik LEE
Korean Journal of Clinical Pharmacy 2023;33(3):195-201
Background:
Hematocrit is usually measured from venous blood collected by invasive venipuncture. This study was performed to determine hematocrit accurately and precisely using minimally invasive volumetric absorptive microsampling (VAMS) technique.Such technique is to be applied to determining hematocrit in various clinical settings for the care, including therapeutic drug monitoring, of neonatal or epileptic patients, or patients with high risk of infection or bleeding.
Methods:
The study was performed using 31 VAMS samples obtained from 21 pancreatic cancer patients. Hematocrit was determined using the values of potassium concentrations obtained from blood in VAMS tips (HctVAMS ). HctVAMS was compared with hematocrit measured from blood collected by venipuncture (HctVP ). The accuracy and precision of HctVAMS in comparison to HctVP were evaluated using BlandAltman plot, Deming regression and mountain plot.
Results:
Bland-Altman plot displayed a random scattering pattern of the differences between HctVAMS and HctVP with the mean bias of −0.010 and the 95% limit of agreement ranging from −0.063 to 0.044.Deming regression for HctVAMS and HctVP line demonstrated very small proportional and constant biases of 1.04 and −0.003, respectively. Mountain plot exhibited a narrow and symmetrical distribution of the differences with their median of −0.011 and central 95% range from −0.049 to 0.033.
Conclusion
Hematocrit was accurately and precisely determined using less invasive VAMS technique. Such technique appears to be applicable to determining hematocrit in situations that venipuncture is not favorable or possible.
4.A Case of Henoch-Schonlein Purpura Presenting with Cholestatic Hepatitis.
Bong Chul SHIN ; Nae Yun HEO ; Mi Seon KANG ; Ju Won LEE ; Seunghyun PARK ; Kyubok JIN ; Jun KANG
Korean Journal of Medicine 2013;84(6):831-835
Hepatobiliary involvement is a rare manifestation of Henoch-Schonlein purpura (HSP). HSP cases related to hepatitis A, B or C virus have been reported but little is known about HSP cases complicated by cholestatic hepatitis without underlying hepatobiliary disease. Here, we report a case of Henoch-Schonlein purpura presenting with cholestatic hepatitis. The patient presented with upper abdominal pain and cholestasis that developed characteristic purpura. The patient was treated conservatively by therapeutic fasting and nutritional support, and liver function recovered 7 weeks after admission.
Abdominal Pain
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Cholestasis
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Fasting
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Hepatitis
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Hepatitis A
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Humans
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Liver
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Nutritional Support
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Purpura
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Purpura, Schoenlein-Henoch
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Viruses
5.Case of the Index Patient Who Caused Tertiary Transmission of COVID-19 Infection in Korea: the Application of Lopinavir/Ritonavir for the Treatment of COVID-19 Infected Pneumonia Monitored by Quantitative RT-PCR
Jaegyun LIM ; Seunghyun JEON ; Hyun Young SHIN ; Moon Jung KIM ; Yu Min SEONG ; Wang Jun LEE ; Kang Won CHOE ; Yu Min KANG ; Baeckseung LEE ; Sang Joon PARK
Journal of Korean Medical Science 2020;35(6):79-
Since mid-December of 2019, coronavirus disease 2019 (COVID-19) infection has been spreading from Wuhan, China. The confirmed COVID-19 patients in South Korea are those who came from or visited China. As secondary transmissions have occurred and the speed of transmission is accelerating, there are rising concerns about community infections. The 54-year old male is the third patient diagnosed with COVID-19 infection in Korea. He is a worker for a clothing business and had mild respiratory symptoms and intermittent fever in the beginning of hospitalization, and pneumonia symptoms on chest computerized tomography scan on day 6 of admission. This patient caused one case of secondary transmission and three cases of tertiary transmission. Hereby, we report the clinical findings of the index patient who was the first to cause tertiary transmission outside China. Interestingly, after lopinavir/ritonavir (Kaletra, AbbVie) was administered, β-coronavirus viral loads significantly decreased and no or little coronavirus titers were observed.
China
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Clothing
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Commerce
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Coronavirus
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Fever
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Hospitalization
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Humans
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Korea
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Male
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Pneumonia
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Thorax
;
Viral Load
6.Case of the Index Patient Who Caused Tertiary Transmission of COVID-19 Infection in Korea: the Application of Lopinavir/Ritonavir for the Treatment of COVID-19 Infected Pneumonia Monitored by Quantitative RT-PCR
Jaegyun LIM ; Seunghyun JEON ; Hyun Young SHIN ; Moon Jung KIM ; Yu Min SEONG ; Wang Jun LEE ; Kang Won CHOE ; Yu Min KANG ; Baeckseung LEE ; Sang Joon PARK
Journal of Korean Medical Science 2020;35(6):e79-
Since mid-December of 2019, coronavirus disease 2019 (COVID-19) infection has been spreading from Wuhan, China. The confirmed COVID-19 patients in South Korea are those who came from or visited China. As secondary transmissions have occurred and the speed of transmission is accelerating, there are rising concerns about community infections. The 54-year old male is the third patient diagnosed with COVID-19 infection in Korea. He is a worker for a clothing business and had mild respiratory symptoms and intermittent fever in the beginning of hospitalization, and pneumonia symptoms on chest computerized tomography scan on day 6 of admission. This patient caused one case of secondary transmission and three cases of tertiary transmission. Hereby, we report the clinical findings of the index patient who was the first to cause tertiary transmission outside China. Interestingly, after lopinavir/ritonavir (Kaletra, AbbVie) was administered, β-coronavirus viral loads significantly decreased and no or little coronavirus titers were observed.
7.A Case of Hypersensitivity Myocarditis.
Seunghyun KWON ; Juyong LEE ; Sung Jin OH ; Jung Rae CHO ; Hee Man KIM ; Haeyoun KANG ; Dong Hwan SHIN ; Se Joong RIM ; Yangsoo JANG ; Namsik CHUNG
Korean Circulation Journal 2002;32(1):71-75
Hypersensitivity myocarditis may result from an allergic reaction to a variety of agents such as antibiotics, anticonvulsants and diuretics. A diagnosis of hypersensitivity myocarditis should be considered in any patient with an ongoing allergic reaction to a drug, evidence of peripheral eosinophilia, an appearance of new electrocardiographic changes, mildly elevated cardiac enzyme, mild cardiomegaly on chest X-ray or unexplained tachycardia. This condition is rarely recognized clinically although it is occasionally diagnosed on endomyocardial biopsy. We report a 25 year-old woman with hypersensitivity myocarditis, which was diagnosed by endomyo-cardial biopsy and successfully treated by immunosuppression therapy with corticosteroids.
Adrenal Cortex Hormones
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Adult
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Anti-Bacterial Agents
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Anticonvulsants
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Biopsy
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Cardiomegaly
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Diagnosis
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Diuretics
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Electrocardiography
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Eosinophilia
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Female
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Glucocorticoids
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Humans
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Hypersensitivity*
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Immunosuppression
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Myocarditis*
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Tachycardia
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Thorax
8.Usefulness of two-dimensional shear wave elastography in diagnosing hepatic veno-occlusive disease in pediatric patients undergoing hematopoietic stem cell transplantation
Yoon Seong LEE ; Seunghyun LEE ; Young Hun CHOI ; Yeon Jin CHO ; Seul Bi LEE ; Jung-Eun CHEON ; Kyung Taek HONG ; Hyoung Jin KANG
Ultrasonography 2023;42(2):286-296
Purpose:
This study aimed to evaluate the usefulness of two-dimensional shear wave elastography (2D-SWE) in diagnosing hepatic veno-occlusive disease (VOD) in pediatric patients.
Methods:
This study retrospectively included pediatric patients who underwent hematopoietic stem cell transplantation (HSCT) between November 2019 and January 2021. All 34 patients (8.7±5.0 years) were examined using 2D-SWE for an initial diagnosis. A subgroup analysis was performed using the data from follow-up examinations of patients diagnosed with VOD. The characteristics of the initial VOD diagnosis were compared with the longitudinal changes observed in VOD patients who underwent multiple ultrasound examinations.
Results:
In total, 19 patients were diagnosed with VOD at 17.6±9.4 days after HSCT. All VOD patients showed hepatomegaly, ascites, and gallbladder wall thickening. Liver stiffness was higher in VOD patients than in non-VOD patients (12.4±1.1 vs. 6.3±0.8 kPa, P<0.001). Liver stiffness values above 7.2 kPa showed 84.2% sensitivity and 93.3% specificity in distinguishing VOD from non-VOD (area under the curve, 0.925; 95% confidence interval, 0.780 to 0.987; P<0.001). A subgroup analysis of 11 patients showed a linear decrease in liver stiffness values after VOD diagnosis with treatment (first, second, and third follow-ups; 13.5±1.7, 11.3±1.4, and 9.5±0.8 kPa, respectively), but without statistical significance in the pairwise analysis.
Conclusion
Liver stiffness measured using 2D-SWE increased in pediatric patients who develop VOD after HSCT. Therefore, liver stiffness can be a predictive and quantitative parameter for diagnosing VOD.
9.Incidence of Breakthrough Reaction in Patients with Prior Acute Allergic-Like Reactions to Iodinated Contrast Media according to the Administration Route.
Yeon Soo KIM ; Young Hun CHOI ; Yeon Jin CHO ; Seunghyun LEE ; Soon Ho YOON ; Chang Min PARK ; Hye Ryun KANG
Korean Journal of Radiology 2018;19(2):352-357
OBJECTIVE: This study assessed the risk of acute allergic-like reactions (AARs) after extravascular administration of iodinated contrast media (ICM) in at-risk patients compared with that after intravascular ICM administration. MATERIALS AND METHODS: From July 2012 to January 2016, 264 patients with a history of moderate or severe reactions to ICM, with re-exposure to ICM intravascularly or extravascularly were included. The incidence of recurrent AARs after ICM re-exposure were assessed according to the administration routes by reviewing electronic medical records and comparison between the two routes. RESULTS: Among 264 patients, 244 patients had been subsequently exposed to ICM intravascularly, 7 patients via an extravascular route and 13 patients with dual re-exposure. Of 257 patients with intravascular ICM re-exposure, 87 (33.9%) had mild to severe recurrent AARs and 143 (19.5%) cases of recurrent AARs occurred among 733 cases of intravascular ICM re-exposure on a case-by-case basis. However, there was no case of recurrent ARR after extravascular administration of ICM in 20 patients (45 cases) with ICM administrated extravascularly. CONCLUSION: For high-risk patients with a history of moderate or severe reactions to ICM, AARs upon extravascular administration of ICM are significantly infrequent compared with intravascular ICM administration.
Anaphylaxis
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Contrast Media*
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Electronic Health Records
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Humans
;
Incidence*
;
Premedication
10.Comparison of the ulnar nerve blockade between intertruncal and corner pocket approaches for supraclavicular block: a randomized controlled trial
Yumin JO ; Jiho PARK ; Chahyun OH ; Woosuk CHUNG ; Seunghyun SONG ; Jieun LEE ; Hansol KANG ; Youngkwon KO ; Yoon-Hee KIM ; Boohwi HONG
Korean Journal of Anesthesiology 2021;74(6):522-530
Background:
The corner pocket (CP) approach for supraclavicular block (SCB) prevents ulnar nerve (UN) sparing due to needle proximity to the lower trunk. Improved ultrasound resolution has suggested that the intertruncal (IT) approach is a suitable alternative method. We compared efficiency of these two approaches on the UN blockade.
Methods:
Sixty patients were randomized to undergo SCB using the ultrasound-guided CP or IT approach. For lower trunk blockade, 10 ml of local anesthetic agents (1 : 1 mixture of 0.75% ropivacaine and 1% lidocaine) were injected in the CP (CP approach) or between the lower and middle trunks (IT approach). Additional 15 ml was injected identically to block the middle and upper trunks in both groups. Sensory and motor blockade was evaluated after intervention.
Results:
Complete sensory blockade (75.9% [22/29] vs. 43.3% [13/30], P = 0.023) and complete motor blockade (82.8% [24/29] vs. 50.0% [15/30], P = 0.017) of the UN at 15 min after SCB were significantly more frequent in the IT than in the CP group. Sensory block onset time of the UN was significantly shorter in the IT compared to the CP group (15.0 [10.0; 15.0] min vs. 20.0 [15.0; 20.0] min; P = 0.012).
Conclusions
The IT approach provided a more rapid onset of UN blockade than the CP approach. These results suggest that the IT approach is a suitable alternative to the CP approach and can provide faster surgical readiness.