This study analyzed the prevalence of metabolic syndrome and influencing factors among adult workers aged 19 to 64. Methods: Data from the ninth Korea National Health and Nutrition Examination Survey conducted in 2022 were utilized. The sample comprised 685 individuals who had measurements of fasting glucose, triglycerides, high-density lipoprotein cholesterol, blood pressure, and waist circumference, which are necessary to diagnose metabolic syndrome. Data analysis was performed using SPSS 26.0, and complex sample logistic regression was conducted to identify factors influencing metabolic syndrome. Results: Among the participants, 34.3% were diagnosed with metabolic syndrome. Significant differences were observed in sex, age, region, marital status, regular worker, and physical activity between participants with and without metabolic syndrome (p < .05). Factors influencing the prevalence of metabolic syndrome included sex, age (with the 19~29 age group showing a significantly lower risk), physical activity, smoking, and perceived stress levels (p < .05). Conclusion: To prevent metabolic syndrome in adult workers, it is essential to promote physical activity, discourage smoking, and encourage effective stress management.

This study analyzed the prevalence of metabolic syndrome and influencing factors among adult workers aged 19 to 64. Methods: Data from the ninth Korea National Health and Nutrition Examination Survey conducted in 2022 were utilized. The sample comprised 685 individuals who had measurements of fasting glucose, triglycerides, high-density lipoprotein cholesterol, blood pressure, and waist circumference, which are necessary to diagnose metabolic syndrome. Data analysis was performed using SPSS 26.0, and complex sample logistic regression was conducted to identify factors influencing metabolic syndrome. Results: Among the participants, 34.3% were diagnosed with metabolic syndrome. Significant differences were observed in sex, age, region, marital status, regular worker, and physical activity between participants with and without metabolic syndrome (p < .05). Factors influencing the prevalence of metabolic syndrome included sex, age (with the 19~29 age group showing a significantly lower risk), physical activity, smoking, and perceived stress levels (p < .05). Conclusion: To prevent metabolic syndrome in adult workers, it is essential to promote physical activity, discourage smoking, and encourage effective stress management.

This study analyzed the prevalence of metabolic syndrome and influencing factors among adult workers aged 19 to 64. Methods: Data from the ninth Korea National Health and Nutrition Examination Survey conducted in 2022 were utilized. The sample comprised 685 individuals who had measurements of fasting glucose, triglycerides, high-density lipoprotein cholesterol, blood pressure, and waist circumference, which are necessary to diagnose metabolic syndrome. Data analysis was performed using SPSS 26.0, and complex sample logistic regression was conducted to identify factors influencing metabolic syndrome. Results: Among the participants, 34.3% were diagnosed with metabolic syndrome. Significant differences were observed in sex, age, region, marital status, regular worker, and physical activity between participants with and without metabolic syndrome (p < .05). Factors influencing the prevalence of metabolic syndrome included sex, age (with the 19~29 age group showing a significantly lower risk), physical activity, smoking, and perceived stress levels (p < .05). Conclusion: To prevent metabolic syndrome in adult workers, it is essential to promote physical activity, discourage smoking, and encourage effective stress management.

This study analyzed the prevalence of metabolic syndrome and influencing factors among adult workers aged 19 to 64. Methods: Data from the ninth Korea National Health and Nutrition Examination Survey conducted in 2022 were utilized. The sample comprised 685 individuals who had measurements of fasting glucose, triglycerides, high-density lipoprotein cholesterol, blood pressure, and waist circumference, which are necessary to diagnose metabolic syndrome. Data analysis was performed using SPSS 26.0, and complex sample logistic regression was conducted to identify factors influencing metabolic syndrome. Results: Among the participants, 34.3% were diagnosed with metabolic syndrome. Significant differences were observed in sex, age, region, marital status, regular worker, and physical activity between participants with and without metabolic syndrome (p < .05). Factors influencing the prevalence of metabolic syndrome included sex, age (with the 19~29 age group showing a significantly lower risk), physical activity, smoking, and perceived stress levels (p < .05). Conclusion: To prevent metabolic syndrome in adult workers, it is essential to promote physical activity, discourage smoking, and encourage effective stress management.

Traumatic rupture of the corpus cavernosum of the penis is rare and has been reported infrequently. We experienced 4 cases of penile fracture for recent 2 years. They occurred during coitus(1 case), masturbation(2 cases), and through blunt trauma(1 case). The former 3 cases were treated with immediate surgical intervention about 12 hours after injury. When the last case patient visited hospital 5 days after injury, the penile abscess treated immediately with surgical intervention had developed. Surgery consisted of complete evacuation of the hematoma or pus and repairing of the tear at the tunica albuginea. The results were excellent, with complete early recovery of erectile function. Delayed wound healing was observed only in a patient who underwent surgery about 5 days after injury, but this did not cause any complication afterward. In our experiences, immediate surgical treatment is recommended in patients with fracture of the penis.
Abscess ; Hematoma ; Humans ; Male ; Penis ; Rupture ; Suppuration ; Wound Healing

PURPOSE: The major pelvic ganglia (MPG) function as a relay center for autonomic pathways to the urogenital organs, such as the urinary bladder, vas deference, and penis. It is well known that adenosine acts as an important neuromodulator in various neuronal tissues. Several studies have suggested that some of these actions are coupled with potassium conductances. However, the exact mechanisms are unclear. Therefore, the roles of adenosine on the various potassium channels, in MPG neurons, were investigated. MATERIALS AND METHODS: Single neurons of the MPGs, located on the lateral surfaces of the prostate gland, from male rats were enzymatically dissociated. Ionic currents were recorded using the whole-cell variant patch-clamp technique. RESULTS: Two types of voltage-dependent outward potassium channels were isolated in the MPG neurons using whole-cell voltage protocols. One was the transient outward potassium current (type A-current, IA), the other was the delayed rectifier potassium current (IKDR). The IA and IKDR were recorded in both adrenergic and nonadrenergic neurons, which were distinguished by the existence of T-type calcium currents. Both the adrenergic and nonadrenergic neurons had the same kind of outward potassium currents. Application of adenosine (10(-4)M) increased the IA reversibly. N-cyclopentyladenosine (CPA, 10(-5)M), an A1 selective agonist, produced the same effect. However, the delayed rectifier components were not affected by the adenosine or CPA. The effects of adenosine and CPA on the IA were mostly prevented by pretreatment with DPCPX, an A1 selective antagonist. CONCLUSIONS: Adenosine increased the IA only, via the selective activation of A1 adenosine receptors. The augmentation of A-currents by adenosine may reduce neuronal firings, and then contribute to regulation of neuronal excitability in male rat MPG neurons.
Adenosine* ; Animals ; Autonomic Pathways ; Calcium ; Fires ; Ganglia* ; Ganglia, Autonomic ; Humans ; Male* ; Neurons* ; Neurotransmitter Agents ; Patch-Clamp Techniques ; Penis ; Potassium ; Potassium Channels ; Prostate ; Rats* ; Receptors, Purinergic P1 ; Urinary Bladder

OBJECTIVE: To determine the prevalence and related characteristics of carpal tunnel syndrome (CTS) in orchardists and to investigate the association between electrodiagnostic severity and physical examinations. METHODS: Between July 2013 and September 2014, 377 subjects (174 men and 203 women) visited the Gyeongsang National University Hospital's Center for Farmer's Safety and Health. All the subjects underwent electrodiagnostic tests and physical examination, including Phalen's test, Tinel's sign, and Durkan's carpal compression test (CCT). The subjects were classified into 2 groups, the normal group and the CTS group, according to electrodiagnostic test results. To determine the related characteristics of CTS, potential variables, including age, sex, drinking, smoking, body mass index, waist circumference, and total work time, were compared between the 2 groups. The association between electrodiagnostic severity and physical examinations was analyzed. RESULTS: CTS was diagnosed in 194 subjects based only on electrodiagnostic test results, corresponding to a prevalence of 51.5%. Among the variables, mean age (p=0.001) and total work time (p=0.007) were significantly correlated with CTS. With respect to the physical examinations, low specificities were observed for Tinel's sign, Phalen's test, and Durkan's CCT (38.4%, 36.1%, and 40.9%, respectively) in the subjects aged ≥65 years. In addition, Phalen's test (p=0.003) and Tinel's sign (p=0.032) in men and Durkan's CCT (p=0.047) in women showed statistically significant differences with increasing CTS severity. The odds ratio was 2.066 for Durkan's CCT in women according to the multivariate logistic regression analysis. CONCLUSION: CTS prevalence among orchardists was high, and Durkan's CCT result was significantly quantitatively correlated with the electrodiagnostic test results. Therefore, Durkan's CCT is another reliable examination method for CTS.
Body Mass Index ; Carpal Tunnel Syndrome* ; Drinking ; Electrodiagnosis ; Female ; Gyeongsangnam-do* ; Humans ; Logistic Models ; Male ; Methods ; Odds Ratio ; Physical Examination ; Prevalence* ; Smoke ; Smoking ; Waist Circumference

Background: We conducted a comprehensive meta-analysis of prospective cohort studies to analyze the effect of circulating vitamin D level on the risk of sudden cardiac death (SCD) and cardiovascular disease (CVD) mortality. Methods: Prospective cohort studies evaluating the association between circulating vitamin D and risk of SCD and CVD mortality were systematically searched in the PubMed and Embase. Extracted data were analyzed using a random effects model and results were expressed in terms of hazard ratio (HR) and 95% confidence interval (CI). Restricted cubic spline analysis was used to estimate the dose-response relationships. Results: Of the 1,321 records identified using the search strategy, a total of 19 cohort studies were included in the final meta-analysis. The pooled estimate of HR (95% CI) for low vs. high circulating vitamin D level was 1.75 (1.49–2.06) with I 2 value of 30.4%. In subgroup analysis, strong effects of circulating vitamin D were observed in healthy general population (pooled HR, 1.84; 95% CI, 1.43–2.38) and the clinical endpoint of SCD (pooled HRs, 2.68; 95% CI, 1.48– 4.83). The dose-response analysis at the reference level of < 50 nmol/L showed a significant negative association between circulating vitamin D and risk of SCD and CVD mortality. Conclusion Our meta-analysis of prospective cohort studies showed that lower circulating vitamin D level significantly increased the risk of SCD and CVD mortality.

The pelvic ganglia provide autonomic innervations to the various urogenital organs, such as the urinary bladder, prostate, and penis. It is well established that both sympathetic and parasympathetic synaptic transmissions in autonomic ganglia are mediated mainly by acetylcholine (ACh). Until now, however, the properties of ACh-induced currents and its receptors in pelvic ganglia have not clearly been elucidated. In the present study, biophysical characteristics and molecular nature of nicotinic acetylcholine receptors (nAChRs) were studied in sympathetic and parasympathetic major pelvic ganglion (MPG) neurons. MPG neurons isolated from male rat were enzymatically dissociated, and ionic currents were recorded by using the whole cell variant patch clamp technique. Total RNA from MPG neuron was prepared, and RT-PCR analysis was performed with specific primers for subunits of nAChRs. ACh dose-dependently elicited fast inward currents in both sympathetic and parasympathetic MPG neurons (EC50; 41.4microliterM and 64.0microliterM, respectively). ACh-induced currents showed a strong inward rectification with a reversal potential near 0 mV in current-voltage relationship. Pharmacologically, mecamylamine as a selective antagonist for alpha3beta4 nAChR potently inhibited the ACh-induced currents in sympathetic and parasympathetic neurons (IC50; 0.53micrometer and 0.22micrometer, respectively). Conversely, alpha- bungarotoxin, alpha-methyllycaconitine, and dihydro-beta-erythroidine, which are known as potent and sensitive blockers for alpha7 or alpha4beta2 nAChRs, below micromolar concentrations showed negligible effect. RT-PCR analysis revealed that alpha3 and beta4 subunits were predominantly expressed in MPG neurons. We suggest that MPG neurons have nAChRs containing alpha3 and beta4 subunits, and that their activation induces fast inward currents, possibly mediating the excitatory synaptic transmission in pelvic autonomic ganglia.
Acetylcholine ; Animals ; Dihydro-beta-Erythroidine ; Ganglia ; Ganglia, Autonomic ; Ganglion Cysts* ; Humans ; Male* ; Mecamylamine ; Negotiating ; Neurons* ; Penis ; Prostate ; Rats* ; Receptors, Nicotinic ; Reverse Transcriptase Polymerase Chain Reaction ; RNA ; Synaptic Transmission ; Urinary Bladder

OBJECTIVES: To investigate the differences in accessing regional hospitals and the utilization rate of hospitals located in other regions for cancer patients by regions. METHODS: Data for the utilization of regional hospitals for cancer patients were obtained from the Korean National Cancer Incidence Databases in 1999 and 2002. We divided the regions into 16 provinces by administrative districts. We using the SAS 9.1.3 to analyze difference of regional self-sufficiency and the Arcview 3.2 to show in a schematize for regional variation of the regional self-sufficiency. RESULTS: There were regional variations in the regional self-sufficiency of cancer patients. Especially, Jeollanam-do(1999 13.6%, 2002 12.8%), Gyeongsangbuk-do(1999 22.0%, 2002 20.7%), and Chungcheongnam-do(1999 27.8%, 2002 27.1%) had low regional self-sufficiency. The regional self-sufficiency in Gyeonggi-do and utilization rate of cancer patients who lived in other regions were increased between 1999 and 2002(regional self-sufficiency: 1999 37.2%, 2002 48.2%). CONCLUSION: The results of this study showed that there were regional variation in utilization of regional hospitals for cancer patients. Accessibility of cancer patients in metropolitan areas was higher than in small size cities, medium size cities, and rural county areas. These results suggested that it should be considered support medical facilities for cancer patients in rural areas where have lower relevance rate.
Gyeonggi-do ; Humans ; Incidence