2.The evaluation of the combined use of serum ?hCG and ultrasound in diagnosis of ectopic pregnancy.
Jong Suk KO ; Ha Bong KIM ; Myeong Suk LEE ; Hyung Sun RYU ; Ho Jun CHOI ; Seung Kwan SHIN
Korean Journal of Obstetrics and Gynecology 1993;36(7):1407-1415
No abstract available.
Diagnosis*
;
Female
;
Pregnancy
;
Pregnancy, Ectopic*
;
Ultrasonography*
3.Clinical study on cesarean hysterectomy.
Sang Yoon JUNG ; Hyung Woo RYU ; Byung Tae LEE ; Moon Su KIM ; Young In KIM ; Yoon Sun LEE ; Seung Bo PARK
Korean Journal of Obstetrics and Gynecology 1991;34(2):209-215
No abstract available.
Hysterectomy*
4.Clinical study on cesarean hysterectomy.
Sang Yoon JUNG ; Hyung Woo RYU ; Byung Tae LEE ; Moon Su KIM ; Young In KIM ; Yoon Sun LEE ; Seung Bo PARK
Korean Journal of Obstetrics and Gynecology 1991;34(2):209-215
No abstract available.
Hysterectomy*
5.Atypical Fracture of the Ulna Associated with 3 Years of Bisphosphonate Medication.
Seung Min RYU ; Doo Hyung YOON ; Sam Guk PARK
The Journal of the Korean Orthopaedic Association 2018;53(3):277-282
There have been many studies regarding the relationship between long-term use of bisphosphonate and atypical femoral fractures in the literature. However, studies regarding atypical fractures of the upper limbs are severely limited, especially in Korea. Here, we report an atypical fracture of the ulna in a patient with bisphosphonate medication for a relatively short period of 3 years without any history of fractures at other sites.
Femoral Fractures
;
Humans
;
Korea
;
Osteoporosis
;
Ulna*
;
Upper Extremity
6.Comparative Analysis of decreased Mental state Patients after Overdose with Sedative-hypnotics
Seung Jae OH ; Soo Hyung CHO ; So Yeon RYU
Journal of The Korean Society of Clinical Toxicology 2022;20(1):8-14
Purpose:
This study was undertaken to investigate how sedative-hypnotics affect the occurrence and severity of the patient’s symptoms. In addition, we conducted a study to determine the type of patients who reacted severely and required hospitalization;patients were accordingly classified as hospitalized patients and patients discharged from the emergency room.
Methods:
From January 2017 to December 2019, we investigated the demographics, drug information, history, laboratory tests, and severity of patients who visited our emergency department and were diagnosed with benzodiazepine, zolpidem, and doxylamine succinate overdose. We further compared details of hospitalized patients and discharged patients.
Results:
Subjects who had overdosed and visited the ED included 120 for benzodiazepine, 147 for zolpidem, and 27 for doxylamine succinate. Comparisons between the three groups revealed differences in their early diagnosis, psychiatric history, and sleep disturbance. Differences between groups were also determined for mental state, poisoning history, treatment received in the intensive care unit, and intubation and ventilator support. In cases of benzodiazepine overdose, we obtained a high hospitalization rate (40.0%), admission to the intensive care unit (24.2%), and intubation rate (18.3%). Comparisons between hospitalized patients and discharged groups showed differences in transferred patients, early diagnosis, and mental state.
Conclusion
Patients poisoned by sedative-hypnotics are increasing every year. In cases of benzodiazepine and zolpidem, the hospitalization rates were high, and benzodiazepine overdose resulted in hospitalization, intensive care unit admission, and pneumonia in a majority of cases. Therefore, active treatment and quick decisions in the emergency room are greatly required.
7.Diagnosis of trichomoniasis by polymerase chain reaction.
Jae Sook RYU ; Hyung Lan CHUNG ; Duk Young MIN ; Youl Hee CHO ; Young Suck RO ; Seung Ryong KIM
Yonsei Medical Journal 1999;40(1):56-60
The clinical usefulness of polymerase chain reaction (PCR) for the diagnosis of trichomoniasis was evaluated in comparison with other conventional tests. PCR was used for specific detection of Trichomonas vaginalis by primers based on the repetitive sequence cloned from T. vaginalis (TV-E650). Between June 1996 and August 1997, 426 patients visited the department of obstetrics and gynecology, Hanyang University Kuri Hospital and were examined for trichomoniasis using wet mount examination, Papanicolaou (Pap) smear, culture and PCR. One hundred and seventy-seven patients (group A) visited with the symptoms of vaginal discharge and 249 patients (group B) visited for regular cervical Pap smear with no vaginal symptoms. From group A (n = 177), 3 infections (2.0%) were detected by wet mount, 6 infections (3.3%) by Pap smear and culture, and 17 infections (10.4%) by PCR. From group B (n = 249), 4 patients (1.6%) were found to have T. vaginalis by culture and 6 infections (2.4%) were detected by PCR. Therefore, in both groups, PCR for T. vaginalis showed a higher detection rate compared with conventional wet mount, Pap smear or culture. The detection by PCR was specific for T. vaginalis since no amplification was detected with DNAs from other protozoa and Candida albicans. The sensitivity and specificity of PCR were 100%. This method could detect T. vaginalis in vaginal discharge at a concentration as low as 1 cell per PCR mixture. These results indicate that PCR could be used as a specific and sensitive diagnostic tool for human trichomoniasis.
Female
;
Human
;
Polymerase Chain Reaction*
;
Sensitivity and Specificity
;
Trichomonas Vaginitis/diagnosis*
8.Reconstruction of the Transmitral Flow Rate Curve with M-Mode,2-Dimensional and Doppler Echocardiography -Validation Study-.
Dong Woon KIM ; Seung Woo PARK ; Duk Kyung KIM ; Kyu Hyung RYU ; Byung Hee OH ; Young Bae PARK ; Yun Shik CHOI ; Jung Don SEO ; Young Woo LEE
Korean Circulation Journal 1989;19(2):273-282
To validate ventricular diastolic phase parameters of reconstructed transmitral flow rate curve by M-mode, 2-dimensional and pulsed Doppler Echocardiography, these parameters were compared with same parameters by left ventriculography. The study population was 22 patients who received both coronary arteriography and echocardiographic examination. Transmitral flow rate curve and left ventricular filling volume curve were reconstructed from transmitral flow velocity curve by pulsed Doppler, mitral annulus diameter by two diameter by two dimensional and diastolic motion of both mitral leafltes by M-mode echocardiography. From left ventriculography, left ventricular filling volume curve and transmitral flow rate curve were made using area-length method by Sandler and Dodge. From trasmitral flow fraction, 1/2 diastolic time filling fraction, normalized peak filling volume, 1/3 diastolic time filling fraction, 1/2 diastolic time fraction, normalized peak early filling rate and ratio of early to late peak filling rate were measured. Correlation between same parameters derived from echocardiography and left ventriculography were observed. 1) Total diastolic filling volume:correlation coefficient r=0.47, P<0.05. 2) 1/3 diastolic time filling fraction:correlation coefficient r=0.90, P<0.001. 3) 1/2 diastolic time filling fraction:correlation coefficient r=0.80, P<0.001. 4) Normalized peak early filling rate:correlation coefficient r=0.57, P<0.01. 5) Ratio of early to late peak filling rate:correlation coefficient r=0.85, P<0.001. Therefore, left ventricular diastolic phase parameters of reconstructed transmitral flow rate curve using, M-mode, 2-dimensional and pulsed Doppler echocardiography seems to be useful for the noninvasive evaluation of the left ventricular diastolic function.
Angiography
;
Echocardiography
;
Echocardiography, Doppler*
;
Echocardiography, Doppler, Pulsed
;
Humans
9.Clinical Experience of Hyperfibrosis Occurred after Silicone Implant Insertion.
Yong Ah RYU ; Hyung Soo KIM ; Ki Ho LEE ; Seung Ryul LEE ; Nak Heon KANG
Journal of the Korean Cleft Palate-Craniofacial Association 2004;5(2):137-140
Facial depression is not rare conditions caused by soft tissue loss or bone distortion. In such conditions, autogenous bone, cartilage and bioacceptible materials are used for soft tissue augmentation. De Nicola used silicone rubber implant first in 1950. That after, silicone implants are used for bone defect and soft tissue augmentation. We experienced 31-year-old male patient who injured open depressed fracture of right temporal bone. He was operated with autogenous bone graft for bone defect area and silicone implants for soft tissue augmentation. After about 6 years later, mass palpated in right temporal area. There was no inflammatory sign in physical examination and CT finding. So we removed hyperfibrotic tissue totally with previous inserted silicone implants and augmented soft tissue with pored Medpor(R) block. In light microscopic findings, only tissue hyperfibrosis were proved without inflammatory cell, such as giant cell or ephithelioid cell.
Adult
;
Cartilage
;
Depression
;
Giant Cells
;
Humans
;
Male
;
Physical Examination
;
Silicone Elastomers
;
Temporal Bone
;
Transplants
10.Comparisons of Oncologic Outcomes between Triple-Negative Breast Cancer (TNBC) and Non-TNBC among Patients Treated with Breast-Conserving Therapy.
Sanghwa KIM ; Hyung Seok PARK ; Jee Ye KIM ; Jegyu RYU ; Seho PARK ; Seung Il KIM
Yonsei Medical Journal 2016;57(5):1192-1198
PURPOSE: The optimum local surgical strategy regarding breast-conserving therapy (BCT) for triple-negative breast cancer (TNBC) is controversial. To investigate whether BCT is appropriate for patients with TNBC, we evaluated the clinical outcomes of BCT in women with TNBC compared to those of women without TNBC, using a large, single-center cohort. MATERIALS AND METHODS: We performed a retrospective analysis of 1533 women (TNBC n=321; non-TNBC n=1212) who underwent BCT for primary breast cancer between 2000 and 2010. Clinicopathological characteristics, locoregional recurrence-free survival (LRFS), and overall survival (OS) were analyzed. RESULTS: Tumors from the TNBC group had a higher T stage (T2 37.4% vs. 21.0%, p<0.001), a lower N stage (N0 86.9% vs. 75.5%, p<0.001), and a higher histologic grade (Grade III 66.8% vs. 15.4%, p<0.001) than the non-TNBC group. There were no differences in 5-year LRFS rates between the TNBC and non-TNBC groups (98.7% vs. 97.8%, p=0.63). The non-TNBC group showed a slightly better 5-year OS than the TNBC group; however, the difference was not significant (96.2% vs. 97.3%, p=0.72). In multivariate analyses, TNBC was not associated with poor clinical outcomes in terms of LRFS and OS [hazard ratio (HR) for LRFS=0.37, 95% confidence interval (CI): 0.10-1.31; HR for OS=1.03, 95% CI: 0.31-3.39]. CONCLUSION: TNBC patients who underwent BCT showed non-inferior locoregional recurrence compared to non-TNBC patients with BCT. Thus, BCT is an acceptable surgical approach in patients with TNBC.
Adult
;
Aged
;
Breast Neoplasms/mortality/pathology/*surgery
;
Disease-Free Survival
;
Female
;
Humans
;
*Mastectomy, Segmental
;
Middle Aged
;
*Neoplasm Recurrence, Local/mortality/pathology
;
Proportional Hazards Models
;
Retrospective Studies
;
Time Factors
;
Treatment Outcome
;
Triple Negative Breast Neoplasms/mortality/pathology/*surgery