No abstract available.
Nipples*

No abstract available.
Neurofibroma*

Proliferating cutaneous epithelial cyst is classified into two subtypes, proliferating trichilemmal cyst and proliferating epidermoid cyst, depending on the mode of keratinization or the origin of the tumors. Proliferating epidermoid cyst is a subepidermal cystic tumor showing, at least in focal areas, a cystic wall lined by epithelium typically seen in epidermoid cyst. We report a case of proliferating epidermoid cyst in a 58-year old man who had a 3x4 cm sized egg shaped cystic tumor on the occipital area of the scalp. Histopathologic examination revealed the tumor was a large epidermoid cyst and a portion of epithelial proliferation projected from the cyst wall into the dermis. The epithelial proliferation was surrounded by paucicellular fibrous stroma.
Dermis ; Epidermal Cyst* ; Epithelium ; Humans ; Middle Aged ; Ovum ; Scalp

Giant cell tumor of tendon sheath is the second most common tumor involving the hands. It usually presents as a slowly growing, lobulated, painless subcutaneous mass. Histologically, the tumor is composed, in variable proportion, of histiocytoid mononuclear cells, multinucleated giant cells, xanthoma cells, and collagenized stroma. Although numerous characteristic multinucleated giant cells are usually noticeable in the tumor, they may be difficult to find, or be entirely absent. We present two cases of giant cell tumor of tendon sheath in which giant cells was not and rarely found respectively.
Collagen ; Giant Cell Tumors* ; Giant Cells* ; Hand ; Tendons* ; Xanthomatosis

No abstract available.
Animals ; Coculture Techniques* ; Embryonic Structures* ; Mice*

BACKGROUND: The purpose of this study was to examine the effects of a single administration of vascular endothelial growth factor (VEGF) in promoting the angiogenesis and thereby reducing the formation of capsular contracture. METHODS: We treated 24 female Sprague-Dawley rats with (1) 5 mM Tris Buffer and 150 mM NaCl 0.1 cc, (2) VEGF 15 µg/0.1 cc, (3) VEGF 150 µg/0.1 cc during placement of the implant, or (4) VEGF 150 µg/0.1 cc and VEGF 300 µg/0.2 cc. We histopathologically measured the thickness of the capsule and the number of blood vessels. RESULTS: All experimental groups had a significant difference in the thickness of the capsule compared to the control group (P<0.001). There was no significant difference between experimental group 2 and experimental group 3. The number of blood vessels formed around the capsule was significantly greater in all the experimental groups compared with the control group (P<0.05). There was no significant difference between the experimental groups. There was a significant negative correlation between the thickness of the capsule and the number of blood vessels (Spearman's correlation coefficient, 0.2732; P<0.0001). CONCLUSIONS: A single administration of VEGF reduced formation of the capsule and increased the vascularity around the implant, supporting the hypothesis that prevention of tissue ischemia can be a treatment strategy for capsular contracture.
Animals ; Blood Vessels ; Breast Implants ; Contracture ; Female ; Humans ; Ischemia ; Rats* ; Rats, Sprague-Dawley ; Silicon* ; Silicones* ; Tromethamine ; Vascular Endothelial Growth Factor A*

Various epidermal changes may be present in the overlying epidermis of dermatofibroma. Follicular basal cell hyperplasia is a relatively rare epidermal change found in 2-23% of dermatofibroma and it should be differentiated from basal cell carcinoma. We report a case of dermatofibroma associated with focal basal cell hyperplasia and a review of the literature.
Carcinoma, Basal Cell ; Epidermis ; Histiocytoma, Benign Fibrous* ; Hyperplasia*

Deep penetrating nevus is a distinctive entity first described by Seab et al. in 1989. This is a variant of melanocytic nevus found on the face, the upper part of the trunk, and the proximal part of the limbs of young adults. It is often deeply pigmented with some variegation in color, and it may lead one to a misdiagnosis of blue nevus or malignant melanoma. Histopathologically the lesions are composed of loosely organized nests of slightly to distinctively pleomorphic pigmented cells that deeply penetrated reticular dermis and often extended into the subcutis. There have been no report of deep penetrating nevus in the Korean literature. We report a case of deep penetrating nevus occurring on the chest in a 19-year-old male.
Dermis ; Diagnostic Errors ; Extremities ; Humans ; Male ; Melanoma ; Nevus* ; Nevus, Blue ; Nevus, Pigmented ; Thorax ; Young Adult

BACKGROUND: Paroxysmal supraventricular tachycardia(PSVT) is frequently associated with ST segment depression or T-wave inversion. However, the mechanism of ST-T changes in the context of various mechanisms of PSVT is not clear. The purpose of this study was to evaluate the prevalence of ST depression or T-wave inversion during PSVT and determine whether these changes are related to the mechanism of PSVT or the rate of the tachycardia. METHODS: Twelve-lead electrocardiograms were recorded during sinus rhythm and during PSVT in 163 patients who underwent an electrophysiologic study for ablation. Tachycardia cycle length, presence of ST depression or T-wave inversion during PSVT and the mechanism of tachycardia were evaluated. Significant ST depression was defined as at least 1mm horizontal or downsloping depression, measured 80ms after the J point and T-wave inversion as inversion of T-wave which was positive in the same lead during sinus rhythm. RESULTS: 1) The mechanism of PSVT analysed for ST segment depression was atrioventricular nodal reentry tachycardia in 60 cases and atrioventricular reentry tachycardia in 111 cases. The mean tachycardia cycle length was 373.8+/-68.0 msec. 2) ST depression and T-wave inversion was observed during PSVT in 56%(96/171) and 45%(77/171) of cases, respectively. 3) Tachycardia cycle length, degree of ST depression and number of leads with ST depression are not different according to the mechanism of PSVT. 4) ST depression and tachycardia cycle length had significant correlation, especially in atrioventricular reentry tachycardia. 5) Leads with T-wave inversion during tachycardia was observed more frequently in atrioventricular reentry tachycardia than atrioventricular nodal reentry tachycardia(p<0.05), but no difference between manifest and concealed bypass tract. CONCLUSIONS: ST segment depression is rate-related phenomenon and not different according to the mechanism of PSVT. Leads with T-wave inversion during tachycardia was observed more frequently in atrioventricular reentry tachycardia.
Depression* ; Electrocardiography ; Humans ; Prevalence ; Tachycardia* ; Tachycardia, Atrioventricular Nodal Reentry ; Tachycardia, Supraventricular

BACKGROUND: Photodynamic therapy (PDT) has been reported to be useful in treating nonmelanoma skin cancers and a variety of benign skin conditions including warts. However, only one case of condyloma acuminata treated with PDT has been reported in Korea. OBJECTIVE: The purpose of this study was to evaluate the complete response rate and side effect of PDT, using light emitting diode (LED) device and 20% 5-aminolevulinic acid (ALA) to treat recalcitrant verruca. METHODS: We treated 8 cases of recalcitrant verruca (3 cases of verruca vulgaris, 3 cases of verruca plana, 2 cases of condyloma acuminata) with PDT, using ALA and a 630+/-50nm LED device. The light intensity was 30-50mW/cm2 and the light dose was 50-120J/cm2. RESULTS: After treatment, two cases of verruca plana showed complete response, and one case of verruca plana, two cases of verruca vulgaris, and two cases of condyloma acuminata showed partial response. However, one case of verruca vulgaris showed no response. There was only burning sensation and/or wheals during treatments. CONCLUSION: Topical PDT may be an alternative therapy in the treatment of verruca, especially of verruca plana.
Burns ; Korea ; Photochemotherapy* ; Sensation ; Skin ; Skin Neoplasms ; Warts*