1.MRI of Intraspinal Cysticercosis.
Seung Cheol KIM ; Moon Hee HAN ; Kee Hyun CHANG ; Gi Seok HAN ; Hee Young HWANG
Journal of the Korean Radiological Society 1995;32(1):33-37
PURPOSE: To describe the MR features of intraspinal cysticercosis. MATERIALS AND METHODS: Medical records and MR images of four cases of intraspinal cysticercosis were retrospectively reviewed. The MR findings were described with regard to the location and signal intensity of the lesions, contrast enhancement, presence or absence of associated intracranial cysticerci, and other findings. RESULTS: There were three cases of subarachnoidal form and one case of intramedullary form. Cysticerci of subarachnoidal form in three cases were located in retromedullary space at C2 level, anterior to cord at C1 -C6 levels, and lumbosacral area, respectively. The signal intensities of the lesions were same as those of CSF. Localized arachnoidal enhancement was found in all three cases. In one case there was a large area of high signal intensity within the spinal cord on T2 weighted image suggesting either ischemia secondary to vascular compromise or inflammatory edema. All of these three cases accompanied intracranial cysticercosis. Intramedullary cysticercosis in one case was shown as a single I cm cystic lesion at C2 level, which showed hypointense signal on T1 weighted image, hyperintense signal on T2-weighted image, and signet-ring-like enhancement. This lesion did not accompany intracranial cysticerci. CONCLUSION: lntraspinal cysticercosis manifested as single or multiple cysts within either spinal cord or subarachnoid space, and were frequently associated with arachnoiditis.
Arachnoid
;
Arachnoiditis
;
Cysticercosis*
;
Edema
;
Ischemia
;
Magnetic Resonance Imaging*
;
Medical Records
;
Retrospective Studies
;
Spinal Cord
;
Subarachnoid Space
2.Characterization of Small Renal Masses Less than 4 cm with Quadriphasic Multidetector Helical Computed Tomography: Differentiation of Benign and Malignant Lesions.
Seung Kwon CHOI ; Seung Hyun JEON ; Sung Goo CHANG
Korean Journal of Urology 2012;53(3):159-164
PURPOSE: To identify the characteristic quadriphasic (unenhanced, corticomedullary, nephrographic, and excretory phase) helical multidetector computed tomography (MDCT) features of renal masses less than 4 cm to distinguish benign from malignant renal masses. MATERIALS AND METHODS: In total, 84 patients were retrospectively analyzed to determine the characteristic features for the prediction of subtypes of small renal masses. The patients' age, gender, and tumor size and CT features, including the presence of intra-tumor degenerative changes, septation, calcification, and wall irregularity, were evaluated. In addition, the degree and pattern of enhancement obtained during four phases were analyzed. The relationship between the subtype of the small renal masses and the gender, morphological features, and pattern of contrast enhancement on the CT was analyzed by using the chi-square test. Tumor size and degree of contrast enhancement were compared by the Mann-Whitney U test. The predictive value of each of the CT features was determined by multivariate logistic regression analysis. RESULTS: Of the 84 small renal masses, 17 (20%) were benign and 67 (80%) were malignant. Univariate analysis revealed that renal cell carcinoma lesions showed heterogeneous enhancement (p=0.002) and higher mean attenuation value on the corticomedullary and nephrographic phases (135.1+/-53.9, p=0.000, and 132.4+/-43.6, p=0.006). The multivariate analysis with logistic regression model showed that only the mean attenuation value on the corticomedullary phase had a statistically significant correlation (p=0.021). CONCLUSIONS: For the characterization of small renal masses, the degree of enhancement on the corticomedullary phase is a valuable parameter. Furthermore, the heterogeneous enhancement pattern and degree of enhancement on the nephrographic phase can provide information for differentiating small renal masses.
Carcinoma, Renal Cell
;
Humans
;
Logistic Models
;
Multidetector Computed Tomography
;
Multivariate Analysis
;
Retrospective Studies
3.Three Cases of Coarctation of the Aorta.
Yu Young CHANG ; Young Ho KIM ; Seung Kyu LEE ; Jun Hee SUL ; Dong Shik CHIN ; Seung Rock HONG
Journal of the Korean Pediatric Society 1983;26(11):1133-1138
No abstract available.
Aortic Coarctation*
4.Sepsis in Patients Receiving Immunosuppressive Drugs in Korea: Analysis of the National Insurance Database from 2009 to 2013.
Seung Young OH ; Songhee CHO ; Hannah LEE ; Eun Jin CHANG ; Se Hee MIN ; Ho Geol RYU
Korean Journal of Critical Care Medicine 2015;30(4):249-257
BACKGROUND: The aim of this study is to evaluate the influence of immunosuppressants on in-hospital mortality from sepsis. METHODS: Using data of the Health Insurance Review & Assessment Service, we collected data from patients who were admitted to the hospital due to sepsis from 2009 to 2013. Based on drugs commonly used for immunosuppression caused by various diseases, patients were divided into three groups; immunosuppressant group, steroid-only group, and control group. Patients with no history of immunosuppressants or steroids were assigned to the control group. To identify risk factors of in-hospital mortality in sepsis, we compared differences in patient characteristics, comorbidities, intensive care unit (ICU) care requirements, and immunodeficiency profiles. Subgroup analysis according to age was also performed. RESULTS: Of the 185,671 included patients, 13,935 (7.5%) were in the steroid-only group and 2,771 patients (1.5%) were in the immunosuppressant group. The overall in-hospital mortality was 38.9% and showed an increasing trend with age. The steroid-only group showed the lowest in-hospital mortality among the three groups except the patients younger than 30 years. The steroid-only group and immunosuppressant group received ICU treatment more frequently (p < 0.001), stayed longer in the hospital (p < 0.001), and showed higher medical expenditure (p < 0.001) compared to the normal group. Univariate and multivariate analyses revealed that age, male gender, comorbidities (especially malignancy), and ICU treatment had a significant effect on in-hospital mortality. CONCLUSIONS: Despite longer hospital length of stay and more frequent need for ICU care, the in-hospital mortality was lower in patients taking immunosuppressive drugs than in patients not taking immunosuppressive drugs.
Comorbidity
;
Health Expenditures
;
Hospital Mortality
;
Humans
;
Immunosuppression
;
Immunosuppressive Agents
;
Insurance*
;
Insurance, Health
;
Intensive Care Units
;
Korea*
;
Length of Stay
;
Male
;
Mortality
;
Multivariate Analysis
;
Risk Factors
;
Sepsis*
;
Steroids
5.One Case of Recovery Phase of Aplastic Crisis in Hereditary Spherocytosis with Family History.
Eun Kyung WON ; Dong Hyeon KIM ; Ho SEUNG ; Chang Hee CHOI
Journal of the Korean Pediatric Society 1990;33(10):1434-1440
No abstract available.
Humans
6.Efficacy of Intrathecal Fentanyl for Tourniquet Pain during Spinal Anesthesia with Hyperbaric Bupivacaine.
Hee Sung YANG ; Seung Yong LEE ; Young Choo KIM ; Suk Bong JUN ; Chang Kyu SHIN
Korean Journal of Anesthesiology 1997;33(4):681-685
BACKGROUND: Tourniquet pain is probably mediated by C-fiber. The ability of fentanyl to interrupt this nociceptive conduction was studied by administering either fentanyl or saline intrathecally along with hyperbaric bupivacaine for spinal anesthesia. METHOD: The incidence of tourniquet pain was evaluated in 60 patients having orthopedic surgery of the lower extremities during spinal anesthesia by administering either 30 mcg fentanyl (group 2) or saline (group 1) along with 0.5% hyperbaric bupivacaine 10 mg. We measured the maximal sensory spread of analgesia to pinprick, the incidence of tourniquet pain, and the sensory anesthesia to pinprick at the onset of tourniquet pain. RESULTS: The average maximal sensory spread of analgesia was the same in both groups (T9). The incidence of tourniquet pain was significantly greater in group 1 (33%) than in group 2 (10%). The sensory levels of anesthesia at the onset of tourniquet pain were not different in two groups. CONCLUSIONS: Intrathecal fentanyl was effective against tourniquet pain for 2 hours of the orthopedic surgery of the lower extremities.
Analgesia
;
Anesthesia
;
Anesthesia, Spinal*
;
Bupivacaine*
;
Fentanyl*
;
Humans
;
Incidence
;
Lower Extremity
;
Orthopedics
;
Tourniquets*
7.Serological and antigenic analysis against borrelia burgdorferi of febrile patients in Korea.
Kyung Hee PARK ; Seung Hyun LEE ; Won Jong JANG ; Sang Mahn KIM ; Woo Hyun CHANG
Journal of the Korean Society for Microbiology 1993;28(5):397-408
No abstract available.
Borrelia burgdorferi*
;
Borrelia*
;
Humans
;
Korea*
8.A case of combined pregnancy in term pregnant woman.
Chang Hee LEE ; Tae Seung CHO ; Young Woo SHIN ; Soo Hyoung SEO ; Dong Han BAE
Korean Journal of Obstetrics and Gynecology 1993;36(3):420-424
No abstract available.
Female
;
Humans
;
Pregnancy*
;
Pregnant Women*
9.Detection of Human Papillomavirus in Lesions of Uterine Cervix Immunohistochemistry and in situ Hybridization.
Chang Soo PARK ; Jong Hee NAM ; Jae Hyuk LEE ; Jong Soon KIM ; Seung Jin OH
Korean Journal of Pathology 1997;31(4):289-297
To evaluate the detection of HPV DNA according to subtype of lesions of uterine cervix and its clinical applicability, in situ hybridization (ISH) and immunohistochemistry for HPV were performed in 189 cases of uterine cervical lesion, including 23 cases of low grade squamous intraepithelial lesion (SIL), 115 cases of high grade SIL and 51 cases of invasive carcinoma. Positive immunostaining, brown precipitate, was mainly noted in the nucleus of koilocytes in the superficial and intermediate layer. Positivity of immunostaining was 21.7% in low grade SIL, 13.0% in high grade SIL and 9.8% in invasive carcinoma. Positive reaction in ISH, red precipitate, was noted in the nucleus of not only koilocytes but also non-koilocytes in the superficial and intermediate layer, and dot precipitate was rarely identified in the nest of squamous cell carcinoma. Based on HPV subtype, 6/11 was 21.7% in low grade SIL, 16/18 was 32.2% and 39.2% in high grade SIL and invasive carcinoma, respectively. With regard to their associated HPV types, low grade SILs were heterogeneous and high grade SILs and invasive carcinomas were related with the high oncogenic risk group only. The correlation of HPV subtypes with panHPV was 91.3% in low grade SIL, 91.3% in high grade SIL and 98.0% in invasive carcinoma. These results suggest that detection of HPV infection by ISH may be a more useful method than immunohistochemistry and application of the HPV subtype probe with the panHPV probe could improve the sensitivity of ISH.
Carcinoma, Squamous Cell
;
Cervix Uteri*
;
DNA
;
Female
;
Humans*
;
Immunohistochemistry*
;
In Situ Hybridization*
10.Isolation of borrelia burgdorferi, the causative agent of lyme disease, from ixodes ticks in Korea.
Kyung Hee PARK ; Seung Hyun LEE ; Woong Jae WON ; Won Jong JANG ; Woo Hyun CHANG
Journal of the Korean Society for Microbiology 1992;27(4):307-312
No abstract available.
Borrelia burgdorferi*
;
Borrelia*
;
Ixodes*
;
Korea*
;
Lyme Disease*
;
Ticks*