1.Clinical Observation of Encephalitis Empasizing the Clinically Suspected Herpes Encephalitis Cases.
Young Sook LEE ; Young Don LEE ; Yong Seung HWANG
Journal of the Korean Pediatric Society 1990;33(5):615-622
No abstract available.
Encephalitis*
;
Encephalitis, Herpes Simplex*
2.Predictive Value of Clinical Examination, Computed Tomography and Magnetic Resonance Imaging in the Clinical Staging of the Cervical Carcinoma.
Young Seung OH ; Seon Kyung LEE ; Seung Bo KIM
Korean Journal of Gynecologic Oncology and Colposcopy 1999;10(4):350-357
A total of 162 patients with invasive cervical cancer was investigated retrospectively with a view to elucidate the efficacy of pretreatment staging procedures of application with intravenous pyelography, cystoscopy, rectosigmoidoscopy. All 72 intravenous pyelograms, 155 sigmoidoscopies, 158 cystoscopies were normal. Of 111 patients with stage Ib who had paraaortic lymph node biopsies, two patients had a positive node(0.02%). Of 51 patients with stage II who had paraaortic lymph node biopsies, five patients had positive paraaortic lymph node(10%). And the accuracy of computed tomography and magnetic resonance imaging in the evaluation of invasive cervical cancer was assessed. In evaluating stage of cervical cancer, clinical staging had an accuracy of 78.9%, compared with 65.7% for CT and 58.9% for MRI. And for detection of parametrial invasion, clincal staging had an accuracy of 85.9%, compared with 85.1% for CT and 78.9% for MRI. Both modalities were comparable in evaluating lymph node metastasis ( 76.1% for CT, 74.4% for MRI ). IVP, cystoscopy and sigmoidoscopy for staging procedure evaluated in this study are unnecessary and should no longer be performed in patients with early stage cervical cancer. In addition, paraaortic lymph node biopsies in the absence of clinically suspicious nodes are not warranted. Compared with CT and MRI, pelvic examination offered improved evaluation of cervical cancer staging, parametrial invasion, but CT and MRI was useful in detecting the pelvic lymph node metastasis which was nearly impossible by clinical evaluation.
Biopsy
;
Cystoscopy
;
Gynecological Examination
;
Humans
;
Lymph Nodes
;
Magnetic Resonance Imaging*
;
Neoplasm Metastasis
;
Retrospective Studies
;
Sigmoidoscopy
;
Urography
;
Uterine Cervical Neoplasms
3.Neurobiology of Alzheimer's Disease.
Young Cho CHUNG ; Seung Woo SEO ; Seung Hwan LEE
Journal of the Korean Society of Biological Psychiatry 2001;8(1):62-70
Alzheimer's disease(AD) is associated with a characteristic neuropathology. The major hallmarks of AD are senile plaques(SPs) and neurofibrillary tangles(NFTs). beta-amyloid protein(Abeta) is derived from the proteolysis of amyloid precursor protein(APP) and then converted to SPs. Mature SPs produce cytotoxicity through direct toxic effects and activation of microglia and complement. NFTs are composed of paired helical filaments(PHFs) including abnormally phosphorylated form of the microtubule-associated protein(MAP) tau and increased tau level in cerebrospinal fluid may be observed in most AD. The aggregation of Abeta and tau formation are thought to be a final common pathway of AD. Acetycholine, dopamine, serotonin, GABA and their receptors are associated with AD. Especially, decreased nicotinic acetylcholine receptors(nAChRs) in AD are reported. Genetic lesions associated with AD are mutations in the structural genes for the APP located on chromosome 21, presenilin(PSN)1 located on chromosome 14 and PSN2 located on chromosome 1. Also, trisomy 21, Apo-E gene located on chromosome 19, PMF locus, low density lipoprotein receptor-related protein and alpha-macroglobulin increase risk of AD. In this article, we will review about the neurobioloby of AD and some newly developed research areas.
Acetylcholine
;
Alzheimer Disease*
;
Amyloid
;
Amyloid beta-Peptides
;
Apolipoproteins E
;
Cerebrospinal Fluid
;
Chromosomes, Human, Pair 1
;
Chromosomes, Human, Pair 14
;
Chromosomes, Human, Pair 19
;
Chromosomes, Human, Pair 21
;
Complement System Proteins
;
Dopamine
;
Down Syndrome
;
gamma-Aminobutyric Acid
;
Genetics
;
Lipoproteins
;
Microglia
;
Neurobiology*
;
Proteolysis
;
Serotonin
4.A Case of Eosinophilic Cystitis in Child.
Journal of the Korean Pediatric Society 1995;38(8):1155-1159
No abstract available.
Child*
;
Cystitis*
;
Eosinophils*
;
Humans
5.A prospective study in the management of the cystic thyroid nodules.
Seung Yeon CHO ; Young Don LEE
Journal of the Korean Surgical Society 1993;45(3):335-342
No abstract available.
Prospective Studies*
;
Thyroid Gland*
;
Thyroid Nodule*
6.Long
The Journal of the Korean Orthopaedic Association 1988;23(2):515-522
We found that the packing of a rolled tensor fascia lata flap after the excision of avascular lunate was reasonably effective in relieving symptoms in 4 patients with advanced Kienbock's disease, even though there was still some residual postoperative loss of wrist motion and grip strength, and the slightly progressive tendencies of earpal collapse and translation as well as rotational deformities of scaphoid. Pre-operatively all patients had pain and limited motion of the wrist as well as weakness of grip. Roentgenographically all had sclerosis, fragmentation and collapse of the lunate. They were analysed each two cases in advanced stage II and III according to the classification by Lichtman. Most had symptoms for longer than two and half years. After removal of the avascular lunate through a dorsal incision, a rolled tensor fascia lata flap was packed to fit the defect. Patients were followed for an average of sixteen months. All were improved clinically but there were somewhat postoperative progress in carpal collapse, translation and rotational deformities of scaphoid roentgenographically.
Classification
;
Congenital Abnormalities
;
Fascia Lata
;
Fascia
;
Hand Strength
;
Humans
;
Osteonecrosis
;
Sclerosis
;
Wrist
9.A Clinical Study of the Upper Extremity Reconstruction in Quadriplegic Patients
In KIM ; Seung Koo RHEE ; Young Soo LEE
The Journal of the Korean Orthopaedic Association 1984;19(2):252-260
No abstract available in English.
Clinical Study
;
Humans
;
Upper Extremity
10.The Study on Performance Evaluation and Improvement of the Information System for the Disabled.
Seung Young LEE ; Seung Hee HO ; Young Moon CHAE ; Deog Young KIM
Korean Journal of Rehabilitation Nursing 2007;10(1):45-57
PURPOSE: The study tried to suggest the ways to improve the national disability welfare information projects with evaluating the present condition of the projects. METHOD: Firstly, the study analyzed the disability information system and disability websites. Secondly, the study found out the problems of the registration of disability and management system through the situation analysis. Finally, the study conducted a survey of the disabled and the information system workers and performance evaluation of the information system. RESULTS: The study offered a proposal of The Disability Unity Management System(DUMS) for the disability registration and management. When the disabled visit the hospital or the public health center, their information is registered automatically in The Disability Unity Management System(DUMS), which helps not to miss out the disability registration. Through this system, they are given the proper service which they need, and the information can be shared with the facilities providing the service for the disabled. CONCLUSION: The Disability Unity Management System(DUMS) contributes significantly in avoiding the repetition of the support for the disabled and improving the quality of service.
Disabled Persons
;
Humans
;
Information Systems*
;
Public Health
;
Registries