1.A Clinical Observation on Antihypertensive Effect of Tripamide(Normonal(R)).
Korean Circulation Journal 1983;13(2):423-427
The antihypertensive effects of once-daily 15mg dose of tripamide(Normonal(R)) were observed in 30 cases of essential hypertension, and the results were as follows; 1) Mean drop in systolic and diastolic pressure were 30 mmHg and 16 mmHg, respectively. 2) In 76.7% of cases, good or fair control of blood pressure was resulted. 3) There was no significant difference in heart rate before and after treatment. 4) There was no significant difference in serum K, BUN, and FBS before and after treatment. 5) There was no any other side effect which required discontinuing the treatment.
Blood Pressure
;
Heart Rate
;
Hypertension
2.INFLUENCE OF TOOTH SURFACE ROUGHNESS AND TYPE OF CEMENT ON RETENTION OF COMPLETE CAST CROWNS.
Kil Su KIM ; Chang Yong SONG ; Seung Geun AHN ; Charn Woon PARK
The Journal of Korean Academy of Prosthodontics 1999;37(4):465-473
Bond strength of luting cements to dentin is a critical consideration for success of complete cast crowns. This study was performed to evaluate the relationship between surface characteristics of teeth prepared for complete cast crowns and retention of cemented restorations. Eighty artificial crowns were cast for standardized complete crown tooth preparations accomplished with the use of a special device on recently extracted human teeth. Coarse diamond(#102R, Shofu) and superfine finishing diamond(#SF102R, Shofu) burs of similar shape were used. Crowns in each group were randomly subdivided into four subgroups of 10 for luting cements selected for this study: zinc phosphate cement (FLECK'S), polycarboxylate cement (Poly-F), reinforced glass ionomer cement (Fuji PLUS), and adhesive resin cement (Panavia 21). Retention was evaluated by measuring the tensile load required to dislodge the artificial crown from tooth preparations with an Instron testing machine, and analysed by one-way ANOVA and Student's t-test. The obtained results were as follows ; 1. When tooth preparation was done with coarse diamond bur, retentive force was diminished in order of Panavia 21, Fuji PLUS, FLECK'S, and Poly-F. Retentive forces showed the significant difference between Fuji PLUS group and FLECK'S group(p<0.001). 2. When tooth preparation was done with superfine diamond bur, retentive force was diminished in order of Fuji PLUS, Panavia 21, FLECK'S and Poly-F. Retentive forces showed the significant difference between Panavia 21 group and FLECK'S group(p<0.001). 3. Retentive force in coarse tooth surfaces was significantly higher than that in superfine tooth surface with all luting cements(p<0.001), and cement residues were almost retained with in the cast crown in all groups.
Adhesives
;
Crowns*
;
Dental Instruments
;
Dentin
;
Glass Ionomer Cements
;
Humans
;
Polycarboxylate Cement
;
Resin Cements
;
Tooth Preparation
;
Tooth*
;
Zinc Phosphate Cement
3.Efficacy of Fluvastatin in Patients with Hypercholesterolemia
Moon Ho KANG ; Sung Gwang LEE ; Jung Ho YOUN ; Tae Suk KIM ; Seung Woon AHN
Journal of Korean Society of Endocrinology 1996;11(1):75-84
Background: Fluvastatin is the first entirely synthetic 3-hydroxy-3-methylglutaryl-coenzyme A(HMG-CoA) reductase inhibitor. Clinical data indicate that this agent exhibits the proven efficacy of its class and also has some theoretical advantages in safety for long-term use because of its unique pharmacololgic property consistent with hepatoselectivity(i.e., low systemic exposure). This study is to evaluate efficacy and safety of fluvastatin in hypercholesterolemic patients in Korea. Methods: An open clinical trial with fluvastatin was conducted in 31 subjects who continued to have high blood cholesterol levels of 6.21 mmol/L(240 mg/dl) or greater after 1 month of lipid-lowering diet plus single blind placebo period. Fluvastatin was administered for 8 weeks with the initial dose of 20 mg per day and if serum cholesterol levels did not fall below 5.20 mmol/L(200 mg/dl) after 4 weeks the dose was increased to 40 mg per day for the second 4 weeks. On each visit every 4 weeks they underwent interview and laboratory tests about side effects and tolerability. Results: The mean % changes in plasma total cholesterol and LDL-cholesterol from baseline were
Cholesterol
;
Creatine Kinase
;
Diet
;
Humans
;
Hypercholesterolemia
;
Korea
;
Oxidoreductases
;
Plasma
;
Sleep Stages
;
Triglycerides
4.A Study of Serum Lipid Levels in Normal Subjects and Various Diseases.
Kum Hyum BAIK ; Do Young OH ; Jae Hwa SONG ; Sun Hwan KIM ; Jae Sang YOO ; Seung Woon AHN
Korean Circulation Journal 1982;12(2):41-48
Total cholesterol and triglyceride were measured in sera of 40 cases of hypertension, 22 cases of myocardial infarction, 14 cases of cerebral thrombosis, 18 cases of subarachnoidal hemorrhage and 30 cases of normal control in Chungnam national University Hospital from October 1980 to September 1981, and the results are as follows; 1) The mean serum total cholesterol and triglyceride levels in normal control group are 153.57+/-40.60mg% and 150.82+/-51.76mg%. 2) The age incidence of these diseases were highest in 6th decade. 3) Serum cholesterol levels of myocardial infarction, hypertension, cerebral thrombosis and subarachinoidal hemorrhage group were higher than that of normal control group. 4) Serum triglyceride levels of acute myocardial infarction and hypertension were significantly higher than that of normal control group, but there is only slightly increases in cerebral thrombosis and subarachinoidal hemorrhage. 5) In general, serum lipid levels are higher in cardiovascular diseases(hypertension and myocardial infarction) than cerebrovascular diseases(cerebral thrombosis and subarachnoidal hemorrhage). 6) Serum Cholesterol and triglyceride levels decreased by administration of pancreatic mucopolysacharide for 1 or 2 months. In conclusion, it seems that high serum cholesterol and triglyceride level may play and important risk factor in development of hypertension and myocardial infarction.
Cholesterol
;
Chungcheongnam-do
;
Hemorrhage
;
Hypertension
;
Incidence
;
Intracranial Thrombosis
;
Myocardial Infarction
;
Risk Factors
;
Thrombosis
;
Triglycerides
5.Effects of hydrofluoric acid concentration and etching time on the shear bond strength between lithium disilicate ceramic and resin cement.
Jae Min SEO ; Charn Woon PARK ; Seung Geun AHN
The Journal of Korean Academy of Prosthodontics 2007;45(4):407-418
PURPOSE: The objective of this study was to evaluate the effects of hydrofluoric acid concentration & etching time on the shear bond strength between IPS Empress 2 ceramic and resin cement. MATERIAL AND METHODS: Thirty three rectangular shape ceramic specimens(20x12x5mm size, IPS Empress 2 core materials) were used for this study. The ceramic specimens divided into ten experimental groups with three specimens in each group and were etched with hydrofluoric acid(4%, 9%) according to different etching times(30s, 60s, 90s, 120s, 180s). Etched surfaces of ceramic specimens were bonded with resin cement(Rely X Unicem) using acrylic glass tube. All cemented specimens were tested under shear loading until fracture on universal testing machine at a crosshead speed of 0.5mm/min and the maximum load at fracture(kg) was recorded. Collected shear bond strength data were analyzed with one way ANOVA and Duncan tests. All etched ceramic surfaces were examined morphologically using SEM(scanning electron microscopy). RESULTS: Shear bond strength of etching group(35.89~68.01 MPa) had four to seven times greater than no-etching group(9.53+/-2.29 MPa). The ceramic specimen etched with 4% hydrofluoric acid for 60s showed the maximum shear bond strength(68.01+/-11.78 MPa). Ceramic surface etched with 4% hydrofluoric acid for 60s showed most retentive surface texture. CONCLUSION: It is considered that 60s etching with 4% hydrofluoric acid is optimal etching methods for IPS Empress 2 ceramic bonding.
Ceramics*
;
Glass
;
Hydrofluoric Acid*
;
Lithium*
;
Resin Cements*
6.A Case of Treatment of Acute Occlusion Complicating Percutaneous Transluminal Coronary Angioplasty.
Yeun Sun KIM ; Jin Iee CHUNG ; Bo In CHUNG ; Jae Woong CHOI ; In Seok CHOI ; Seung Woon AHN ; Eak Kyun SHIN
Korean Circulation Journal 1991;21(5):932-939
Management of unstable angina has evolved progressively. Although coronary angioplasty has recently shown to be relatively safe and effective treatment strategy for unstable angina, aute occlusion due to intracoronary thrombus accumulation during or immediately after coronary angioplasty remains to be one of the most common serious complication of this procedure. Intracoronary urokinase has been used to treat flow-limiting intracoronary thrombus accumulation that complicated initial successful percutaneous transluminal coronary angioplasty(PTCA) in unstable angina patient, which made the patient stablilzed. Thus in patient with flow-limiting intracoronary thrombus accumulation complicating PTCA, intracoronary urokinase proved to be highly effective in restoring vessel patency and preventing acute myocardial infarction. We report a case of successful revascularization with intracoronary infusion of urokinase in patient with intracoronary thrombus accumulation that complicated PTCA.
Angina, Unstable
;
Angioplasty
;
Angioplasty, Balloon, Coronary*
;
Humans
;
Myocardial Infarction
;
Thrombosis
;
Urokinase-Type Plasminogen Activator
7.Effect of chemical treatment on the bioactivity of titanium.
Kwan Sik MIN ; Min Ho LEE ; Seung Geun AHN ; Charn Woon PARK
The Journal of Korean Academy of Prosthodontics 2005;43(4):562-571
STATEMENT OF PROBLEM: Titanium is widely used as an implant material for artificial teeth. Also, studies on surface treatment to form a fine passive film on the surface of commercial titanium or its alloys and improving bioactivity with bone have been carried out. However, there is insufficient data about the biocompatibility of the implant materials in the body. PURPOSE: The purpose of this study was to examine whether the precipitation of apatite on titanium metal is affected by surface modification. MATERIALS AND METHODS: Specimens chemically washed for 2 minute in a 1:1:1.5 (in vol%) mixture of 48% HF, 60% HNO3 and distilled water. Specimens were then chemically treated with a solution containing 97% H2SO4 and 30% H2O2 at 40 degrees C for 1 hour, and subsequently heat-treated at 400 degrees C for 1 hour. All specimens were immersed in the HBSS with pH 7.4 at 36.5 degrees C for 15 days, and the surface were examined with TF-XRD, SEM, EDX and XPS. Also, commercial purity Ti specimens with and without surface treatment were implanted in the abdominal connective tissue of mice for 4 weeks. Conventional aluminium and stainless steel 316L were also implanted for comparison. RESULTS AND CONCLUSIONS: The results obtained were summarized as follows. 1. An amorphous titania gel layer was formed on the titanium surface after the titanium specimen was treated with a H2SO4 and H2O2 solution. The average roughness was 2.175 micrometer after chemical surface treatment. 2. The amorphous titania was subsequently transformed into anatase by heat treatment at 400 degree C for 1 hour. 3. The average thickness of the fibrous capsule surrounding the specimens implanted in the connective tissue was 46.98 micrometer in chemically-treated Ti, and 52.20, 168.65 and 100.95 micrometer, respectively in commercial pure Ti, aluminum and stainless steel 316L without any treatment.
Alloys
;
Aluminum
;
Animals
;
Connective Tissue
;
Hot Temperature
;
Hydrogen-Ion Concentration
;
Mice
;
Stainless Steel
;
Titanium*
;
Tooth, Artificial
;
Water
8.A Study on the Synthesis and Its Biodistribution of C - 11 and F - 18 Labelled Choline.
Seung Dae YANG ; Sang Wook KIM ; Yong Sup SUH ; Kwon Soo CHUN ; Soon Hyuk AHN ; Min Goo HUR ; Sang Moo LIM ; Sung Woon HONG ; Kook Hyun YU
Korean Journal of Nuclear Medicine 2001;35(3):185-191
No abstract available.
Choline*
9.A Case of Granular Cell Tumor of the Esophagus.
Soo Kwan BANG ; Ki Baik HAHM ; Eun Ju KIM ; Seung Woon PAIK ; Yong Jin AHN ; Se Ok YOON ; Sung Ran HONG ; Hee Sook KIM
Korean Journal of Gastrointestinal Endoscopy 1992;12(1):13-17
For many years, the histogenesis of the granular cell tumor was controversial and this resulted in the tumor being given more than 20 synonyms. Abrikossoff, reporting on the fiist granular cell tomor, favored a muscle origin, but other authora have postulated a fibroblastic or a histiocytic origin. Recently, the concept of Schwann cell origin, supported by electron microscopic studies and immunohistochemistry of S-100 protein, has gained wider recognition. Approximately 90 cases of esophageal granular cell tumor have been reported in the literature, representing about 2% incidence of all reported granular cell tumor, In Korea, only four cases of granular cell tumors were reported in the literatures including the cases occuring in the cecum, colon, and anus until now. Recently we experienced 46-years old women with granular cell tumor of the esophagus, which might be the second case in Korean literature.
Anal Canal
;
Cecum
;
Colon
;
Esophagus*
;
Female
;
Fibroblasts
;
Granular Cell Tumor*
;
Humans
;
Immunohistochemistry
;
Incidence
;
Korea
;
Middle Aged
;
S100 Proteins
10.A Case of Primitive Neuroectodermal Tumor of the Uterus.
Soo Hee KIM ; Hye Sung MOON ; Han Moie PARK ; Seung Cheol KIM ; Woon Sup HAN ; Jung Ja AHN
Korean Journal of Obstetrics and Gynecology 2003;46(2):479-483
Primitive neuroectodermal tumor (PNET) is a rare tumor derived from fetal neuroectodermal cells. These tumors occur in the central nervous system and peripheral locations, but the occurrence of primitive neuroectodermal tumors located in the uterus is extremely rare. We present a 53-year-old woman with primitive neuroectodermal tumor of the uterus confirmed by immunohistochemical staining. We have experienced one case of PNET of the uterus and wish to report with brief review of concerned literature.
Central Nervous System
;
Female
;
Humans
;
Middle Aged
;
Neural Plate
;
Neuroectodermal Tumors, Primitive*
;
Uterus*