1.The Incidence of the Epstein-Barr Virus Nuclear Antigen in Non-Hodgkin's Lymphomas of the Gastrointestinal Tract.
Seung Wook JUNG ; Hyun Jin CHO ; Ho Jong JEON
Journal of the Korean Surgical Society 1998;54(6):883-890
The Epstein-Barr virus(EBV) is known to play a causal role in oncogenesis and to be associated with endemic Burkitt's lymphomas, B cell lymphomas in immunocompromised patients, and nasopharyngeal carcinomas. More recently, EBV has also associated with Hodgkin's disease, B cell lymphomas in non-immunocompromised patients, and T-cell lymphomas. Twenty eight cases of a non-Hodgkin's lymphoma of gastrointestinal tract were investigated to determine both the immunophenotype by using immunohistochemical staining and the incidence of the EBV nuclear antigen by using the polymerase chain reaction. Twenty-four of the 28 cases(85.7%) were B-cell type, and 4 of the 28 cases(14.3%) are of T-cell type. The EBV nuclear antigen was detected in three of the 28 cases(10.7%), including two cases of B-cell lymphoma of the stomach and one case of T-cell lymphoma of the small bowel. The EBV nuclear antigen was more frequently found in malignant lymphomas arising in the intestine(1/4) than in stomach(2/16). EBV positivity (25%) in T-cell NHLs was rather higher than EBV positivity (8.3%) in B-cell NHLs. Further expanded evaluations on the role of EBV in the tumorigenesis of a gastrointestinal malignant lymphomas are necessary because the cases of gastrointestinal lymphomas examined were very limited.
B-Lymphocytes
;
Burkitt Lymphoma
;
Carcinogenesis
;
Gastrointestinal Tract*
;
Herpesvirus 4, Human*
;
Hodgkin Disease
;
Humans
;
Immunocompromised Host
;
Incidence*
;
Lymphoma
;
Lymphoma, B-Cell
;
Lymphoma, Non-Hodgkin*
;
Lymphoma, T-Cell
;
Polymerase Chain Reaction
;
Stomach
;
T-Lymphocytes
2.Prognosis of extraventricular drainage in childhood tuberculous meningits.
Hye Jeong JEON ; Ki Joong KIM ; Tae Sung KO ; Dong Wook KIM ; Yong Seung HWANG
Journal of the Korean Child Neurology Society 1993;1(1):72-82
No abstract available.
Drainage*
;
Prognosis*
3.Serous and mucinous cystadenoma of the pancreas: report of three cases.
Chang Yeul CHA ; Wook KIM ; Il Young PARK ; Hae Myung JEON ; Seung Nam KIM ; Jong Nam WON ; Eung Seul HYUN
Journal of the Korean Surgical Society 1993;45(2):286-292
No abstract available.
Cystadenoma, Mucinous*
;
Mucins*
;
Pancreas*
4.Effect of Tightening Torque on Abutment-Fixture Joint Stability using 3-Dimensional Finite Element Analysis.
Tae Gwan EOM ; Seung Woo SUH ; Gyeo Rok JEON ; Jung Wook SHIN ; Chang Mo JEONG
The Journal of Korean Academy of Prosthodontics 2009;47(2):125-135
STATEMENT OF PROBLEM: Loosening or fracture of the abutment screw is one of the common problems related to the dental implant. Generally, in order to make the screw joint stable, the preload generated by tightening torque needs to be increased within the elastic limit of the screw. However, additional tensile forces can produce the plastic deformation of abutment screw when functional loads are superimposed on preload stresses, and they can elicit loosening or fracture of the abutment screw. Therefore, it is necessary to find the optimum tightening torque that maximizes a fatigue life and simultaneously offer a reasonable degree of protection against loosening. PURPOSE: The purpose of this study was to present the influence of tightening torque on the implant-abutment screw joint stability with the 3 dimensional finite element analysis. MATERIAL AND METHODS: In this study, the finite element model of the implant system with external butt joint connection was designed and verified by comparison with additional theoretical and experimental results. Four different amount of tightening torques (10, 20, 30 and 40 Ncm) and the external loading (250 N, 30degrees C) were applied to the model, and the equivalent stress distributions and the gap distances were calculated according to each tightening torque and the result was analyzed. RESULTS: Within the limitation of this study, the following results were drawn; 1) There was the proportional relation between the tightening torque and the preload. 2) In case of applying only the tightening torque, the maximum stress was found at the screw neck. 3) The maximum stress was also shown at the screw neck under the external loading condition. However in case of applying 10 Ncm tightening torque, it was found at the undersurface of the screw head. 4) The joint opening was observed under the external loading in case of applying 10 Ncm and 20 Ncm of tightening torque. 5) When the tightening torque was applied at 40 Ncm, under the external loading the maximum stress exceeded the allowable stress value of the titanium alloy. CONCLUSION: Implant abutment screw must have a proper tightening torque that will be able to maintain joint stability of fixture and abutment.
Alloys
;
Dental Implants
;
Fatigue
;
Finite Element Analysis
;
Head
;
Joints
;
Neck
;
Plastics
;
Titanium
;
Torque
5.Clinical analysis of tension free vaginal tape combined with hysterectomy.
Seung Wook JEON ; Ok Joo AHN ; Chun Hoe KU ; Seong Jun YOON ; Chan Yong PARK
Korean Journal of Obstetrics and Gynecology 2006;49(7):1527-1532
OBJECTIVE: This study was performed to evaluate the efficacy, safety and complications of tension-free vaginal tape (TVT) combined with total hysterectomy under general anesthesia. METHODS: Retrospective comparison of 76 women treated by TVT procedure with total hysterectomy from January 2003 to December 2003. All patients had undergone preoperative evaluation including history taking, physical examination, pelvic examination, 1-hour pad test and urodynamic test, and then were operated under general anesthesia. There were 65 patients combined with LAVH (laparoscopic assisted vaginal hysterectomy), 6 patients combined with VTH (vaginal total hysterectomy) and 5 patients combined with TAH (total abdominal hysterectomy). RESULTS: The mean follow up and hospital day were respectively 13 months (range 6-18 months) and 7.6 days (range 6-15 days). Objective and subjective success rate were respectively 97.4% (cured 92.1%, improved 5.3%) and 97.4% (cured 88.1%, improved 9.3%). Preoperative and postoperative 1-hour pad test were respectively 36.4 gm and 4.1 gm (p<0.001). Complications were bladder perforation (6.6%), voiding dysfunction (7.9%) and overactive bladder syndrome (7.9%). CONCLUSION: Conclusively, the cure rate was 88.1% in the TVT combined with hysterectomy when performed under general anesthesia.
Anesthesia, General
;
Female
;
Follow-Up Studies
;
Gynecological Examination
;
Humans
;
Hysterectomy*
;
Physical Examination
;
Retrospective Studies
;
Suburethral Slings*
;
Urinary Bladder
;
Urinary Bladder, Overactive
;
Urodynamics
6.A Case of Caudal Regression Syndrome Diagnosed by Prenatal Ultrasonography.
Young MOON ; Ji Hyun KIM ; Ock Ju AHN ; Seung Wook JEON ; Byung Cheol HWANG
Korean Journal of Obstetrics and Gynecology 2005;48(7):1788-1792
Caudal regression syndrome is rare malformative syndrome characterized by lower vertebral agenesis, accompanied by abnormalities of the pelvis, lower extremities and urogenital malformation. Although the cause is not clear, hyperglycemia during the organogenesis may be important teratogen. Strict evaluation of diabetes and its control in preconception and early pregnancy are important to prevent this malformation. And ultrasonography in the first trimester should be recommended for early detection of this syndrome. We report a case of caudal regression syndrome detected by prenatal ultrasonography of the gestational diabetic mother.
Female
;
Humans
;
Hyperglycemia
;
Lower Extremity
;
Mothers
;
Organogenesis
;
Pelvis
;
Pregnancy
;
Pregnancy Trimester, First
;
Ultrasonography
;
Ultrasonography, Prenatal*
7.Systemic Amyloidosis after Operation of Gastric Cancer.
Seung Nam CHOI ; Hun JUNG ; Se Jung OH ; Wook KIM ; Hae Myung JEON ; Ah Won LEE
Journal of the Korean Surgical Society 2004;66(4):342-346
Systemic amyloidosis after gastric cancer surgery is a very rare phenomenon. Less than ten such cases have been reported in the international literature. Although systemic amyloidosis has been reported to be associated with lymphoma, multiple myeloma, and renal cell carcinoma, its association with gastric cancer remains unclear. We report a case of a 64-year-old male who developed systemic amyloidosis 24 months after a Billroth-I gastrectomy for gastric cancer, and provide a brief review of the literature.
Amyloidosis*
;
Carcinoma, Renal Cell
;
Gastrectomy
;
Humans
;
Lymphoma
;
Male
;
Middle Aged
;
Multiple Myeloma
;
Stomach Neoplasms*
8.Immature Teratoma of the Nasal Cavity.
Seon Tae KIM ; Byung Wook YOO ; Jeong Gi JEON ; Seung Yeon HA
Korean Journal of Otolaryngology - Head and Neck Surgery 2000;43(3):340-343
Teratomas are embryonal neoplasms that show characteristics from all three germ layers(ectoderm, endoderm, and mesoderm). These tumors are frequently present in infancy and childhood. Teratomas are classified into three groups : mature teratoma, immature teratoma, and teratomas with malignant elements. The histopathologic findings of immature teratoma is primitive neuroepithelial cells compounding pseudostratified tubular formations. The pure immature teratoma accounts for fewer than 1% of all germ cell malignancies. The immature teratomas in nasal cavity are very rare tumor. These tumors are often presented as neonatal respiratory distress, nasal obstruction and epistaxis. We report a case of histologically confirmed immature teratoma in nasal cavity in 48 years old man with review of the literature.
Endoderm
;
Epistaxis
;
Germ Cells
;
Humans
;
Middle Aged
;
Nasal Cavity*
;
Nasal Obstruction
;
Neoplasms, Germ Cell and Embryonal
;
Neuroepithelial Cells
;
Teratoma*
9.Cytologic Features of Glassy Cell Carcinoma of the Uterine Cervix: Three Cases Report.
Seok Hoon JEON ; Seung Sam PAIK ; Won Mi LEE ; Se Jin JANG ; Yong Wook PARK ; Moon Hyang PARK ; Jung Dal LEE
Korean Journal of Cytopathology 1996;7(2):197-201
Glassy cell carcinoma is an unusual neoplasm of the uterine cervix that accounts for 1~2% of all cervical malignancy. It is a rapidly progressive and biologically aggressive disease with poor response to therapy. This tumor is considered to be a poorly differentiated mixed adenosquamous carcinoma. The cytologic findings are characterized by tumor cells arranged predominantly in syncytial like aggregates and an inflammatory background. The tumor cells have moderate amounts of eosinophilic or amphophilic cytoplasm, which is often finely granular. The nuclei are relatively large and have fine chromatin with prominent eosinophilic nucleoli. Cytologically, glassy cell carcinoma is most likely to be confused with large cell nonkeratinizing squamous cell carcinoma and with atypical reparative cells. Herein, we report three cases of glassy cell carcinoma of the uterine cervix diagnosed by cervicovaginal smear and confirmed by histologic section with review of literatures.
Carcinoma, Adenosquamous
;
Carcinoma, Squamous Cell
;
Cervix Uteri*
;
Chromatin
;
Cytoplasm
;
Eosinophils
;
Female
10.Health-Related Quality of Life Changes in Prostate Cancer Patients after Radical Prostatectomy: A Longitudinal Cohort Study
Dong Wook SHIN ; Sang Hyub LEE ; Tae Hwan KIM ; Seok Joong YUN ; Jong Kil NAM ; Seung Hyun JEON ; Seung Chol PARK ; Seung Il JUNG ; Jong Hyock PARK ; Jinsung PARK
Cancer Research and Treatment 2019;51(2):556-567
PURPOSE: Health-related quality of life (HRQOL) information related to radical prostatectomy (RP) is valuable for prostate cancer (PC) patients needing to make treatment decisions. We aimed to investigate HRQOL change in PC patients who underwent three types of RP (open, laparoscopic, or robotic) and compared their HRQOL with that of general population. MATERIALS AND METHODS: Patients were prospectively recruited between October 2014 and December 2015. European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire (EORTC QLQ-C30) and PC-specific module (PR25) were administered before surgery (baseline) and at postoperative 3 and 12 months. At each time point, HRQOL was compared, and a difference of 10 out of 0-100 scale was considered clinically significant. RESULTS: Among 258 screened patients, 209 (41 open, 63 laparoscopic, and 105 robotic surgeries) were included. Compared to baseline, physical, emotional, and cognitive functioning improved at 12 months. Role functioning worsened at 3 months, but recovered to baseline at 12 months. Pain, insomnia, diarrhea, and financial difficulties also significantly improved at 12 months. Most PR25 scales excluding bowel symptoms deteriorated at 3 months. Urinary symptoms and incontinence aid recovered at 12 months, whereas sexual activity and sexual function remained poor at 12 months. Clinically meaningful differences in HRQOL were not observed according to RP modalities. Compared to the general population, physical and role functioning were significantly lower at 3 months, but recovered by 12 months. Social functioning did not recover. CONCLUSION: Most HRQOL domains showed recovery within 12 months after RP, excluding sexual functioning and social functioning. Our findings may guide patients considering surgical treatment for PC.
Cohort Studies
;
Diarrhea
;
Humans
;
Prospective Studies
;
Prostate
;
Prostatectomy
;
Prostatic Neoplasms
;
Quality of Life
;
Sexual Behavior
;
Sleep Initiation and Maintenance Disorders
;
Weights and Measures