BACKGROUND: Total intravenous anesthesia with propofol can cause respiratory depression and apnea especially during induction of anesthesia. To study the possibility of reversal of respiratory depression during anesthesia with propofol, pretreated with nabuphine or not, the respiratory effects of doxapram to spontaneously ventilating patients were investigated. METHODS: Patients were divided into 4 groups - saline-propofol-saline group (SPS), saline-propofol- doxapram group (SPD), nalbuphine-propofol-saline group (NPS), and nalbuphine-propofol-doxapram group (NPD). After saline or nalbuphine pretreatment, anesthesia was induced with propofol and then doxapram or saline was intravenously injected. Apneic time interval, blood pressure, heart rate, respiratory rate, minute ventilation, end tidal CO2 partial pressure and oxygen saturation were measured in every minutes during induction of anesthesia. Percent changes of each values were compared. RESULTS: There is no differences in apneic time intervals in each groups. The percent change of first minute ventilation in SPD group after doxapram injection unchanged significantly compared with those depressions of SPS, NPS and NPD group (p<0.05). Respiratory rates increased in SPD and SPS groups after laryngeal mask insertion. There is no differences in minute ventilation, respiratory rate and end-tidal CO2 concentration between nalbuphine pretreated groups regardless of doxapram injection. CONCLUSIONS: Doxapram has effect in increasing minute ventilation after propofol induction within first few minutes, but it cannot reverse respiratory depression during propofol induction pretreated with nalbuphine.
Anesthesia ; Anesthesia, Intravenous* ; Apnea ; Blood Pressure ; Depression ; Doxapram* ; Heart Rate ; Humans ; Laryngeal Masks ; Nalbuphine* ; Oxygen ; Partial Pressure ; Propofol* ; Respiratory Insufficiency ; Respiratory Rate ; Ventilation

The retinal blood bessels exit the optic disc and branch in a complex pattern to serve the metabolic need of the inner retina. As the vessels traverse the retina, the arteries and veins frequently cross one another. Recently, there has been renewed iterest in the orientation of the crossing retinal vessels at arteriovenous intersections, particularly as it relates to the risk of branch retinal vein occlusion. The authors studied standard fundus photographs of 30 subjects(60 eyes) who don't habve any retinal and systemic disorders. Arteriovenous crossings were analized for fundus location and relative orientation of the crossing vessels(vein-posterior or vein-anterior). In the superotemporal quadrant, A-V crossings were a greater number, distributed closer to the optic disc than the inferotemporal quadrant. Also a greater proportion of crossings was vein-posterior than the inferotemporal quadrant. These findings may explain the predilection for branch retinal vein occlusions to occur frequency in the superotemporal quadrant.
Arteries ; Retina* ; Retinal Vein Occlusion ; Retinal Vessels ; Retinaldehyde ; Veins

To study the morphological anatomy of ophthalmic artery and its branches in the Korean adults, the author dissected fifteen cadaver orbits, and reviewed fifty carotid angiograms and ten high resolution magnetic resonance images of orbit. In 8 of 15(53.3%) cadavers the ophthalmic artery arises at the upper medial circumference of the internal carotid artery in the cerebral portion of the intracranial cavity. The ophthalmic artery crosses over the optic verve in 21 of 25 cases(84.0%: Cadaver 11/15, Orbit MRI 10/10) and passes under the optic verve in 4 of 25 cases(16.0%: Cadaver 4/15, Orbit MRI(10/10). Average distance from its origin to its first branch was 21.9mm. The central retinal artery and medial posterior ciliary artery were identified its frist branch in 7 of 15 cases(46.7%). The tortuous central retinal artery courses forward inferior to the optic verve and mostly enters inferomedial side of the optic nerve in 9 of 15 cases(60.0%), penetrating into dural sheath at 13.0mm behind the globe. There were no significant difference in sexually or laterality(p>0.05). This result shares great deal of similarity with the previous reports(p>0.05).
Adult* ; Cadaver ; Carotid Artery, Internal ; Ciliary Arteries ; Humans ; Magnetic Resonance Imaging ; Ophthalmic Artery* ; Optic Nerve ; Orbit ; Retinal Artery*

No abstract available.
Humans ; Parents* ; Siblings*

Microphthalmos is a uncommon congenital ocular anomaly and the term is justified in that in all cases the eyes are smaller than normal. Microphthalmos is classified as various forms according to degrees of developmental abnormality. The authors experienced a case of microphthalmos with a large cyst in one eye and colobomatous microphthalmos in the other eye.
Coloboma ; Microphthalmos*

Lymphoma forms the largest group of lymphoproliferative disorder in the orbit. Orbit CT scan and biopsy are very helpful for diagnosis. Main treatment is radiotherapy and chemotherapy. The authors experienced a case of orbital lymphoma in a 45-year-old male who visited our hospital due to proptosis of the right eye. Histopathologic result showed diffuse small lymphocytic Non-Hodgkin's lymphoma. We present this case and discuss its management.
Biopsy ; Diagnosis ; Drug Therapy ; Exophthalmos ; Humans ; Lymphoma* ; Lymphoma, Non-Hodgkin ; Lymphoproliferative Disorders ; Male ; Middle Aged ; Orbit* ; Radiotherapy ; Tomography, X-Ray Computed

No abstract available.
Gelatin Sponge, Absorbable* ; Hemorrhage* ; Thrombin*

No abstract available.
Abruptio Placentae* ; Female ; Pregnancy

No abstract available.
Abruptio Placentae* ; Female ; Pregnancy

No abstract available.
Calcium* ; Fetal Blood* ; Phosphorus*