1.Analysis of Choroidal Thickness Measured Using RTVue and Associated Factors in Open-Angle Glaucoma.
Sang Wook JIN ; Woo Seok CHOI ; Hong Ryung SEO ; Seung Soo RHO ; Sae Heun RHO
Journal of the Korean Ophthalmological Society 2015;56(7):1065-1074
PURPOSE: To compare the macular choroidal thickness, ganglion cell complex thickness, peripapillary choroidal thickness and retinal nerve fiber layer thickness among normal, primary open angle glaucoma (POAG) and normal tension glaucoma (NTG) patients using RTVue (Fourier-domain optical coherence tomography; Optovue, Fremont, CA, USA). METHODS: A retrospective analysis of 32 normal controls, 32 POAG and 52 NTG patients was performed. Choroidal thickness, ganglion cell complex thickness and retinal nerve fiber layer thickness were compared among normal controls, POAG and NTG subjects. Additionally, the factors influencing choroidal thickness (age, axial length, spherical equivalent, central corneal thickness, mean deviation, nocturnal dip, blood pressure variability) were analyzed. RESULTS: A total of 32 normal controls, 32 POAG and 52 NTG patients were enrolled in this study. Macular and peripapillary choroidal thicknesses were significantly thinner in the NTG patients. In NTG subjects, the significant influencing factors associated with macular and peripapillary choroidal thicknesses were age, axial length, nocturnal dip (diastolic blood pressure), diastolic blood pressure variability and ganglion cell complex thickness. In POAG patients, significant influencing factors associated with macular and peripapillary choroidal thicknesses were age and axial length. CONCLUSIONS: Choroidal thickness was significantly thinner in NTG patients compared with normal controls and POAG patients. Factors influencing choroidal thickness in NTG patients were age, axial length, nocturnal dip (diastolic blood pressure), diastolic blood pressure variability and ganglion cell complex thickness. In POAG patients, significant factors influencing choroidal thickness were age and axial length.
Blood Pressure
;
Choroid*
;
Ganglion Cysts
;
Glaucoma, Open-Angle*
;
Humans
;
Low Tension Glaucoma
;
Nerve Fibers
;
Retinaldehyde
;
Retrospective Studies
;
Tomography, Optical Coherence
2.Analysis of Choroidal Thickness Measured Using RTVue and Associated Factors in Open-Angle Glaucoma.
Sang Wook JIN ; Woo Seok CHOI ; Hong Ryung SEO ; Seung Soo RHO ; Sae Heun RHO
Journal of the Korean Ophthalmological Society 2015;56(7):1065-1074
PURPOSE: To compare the macular choroidal thickness, ganglion cell complex thickness, peripapillary choroidal thickness and retinal nerve fiber layer thickness among normal, primary open angle glaucoma (POAG) and normal tension glaucoma (NTG) patients using RTVue (Fourier-domain optical coherence tomography; Optovue, Fremont, CA, USA). METHODS: A retrospective analysis of 32 normal controls, 32 POAG and 52 NTG patients was performed. Choroidal thickness, ganglion cell complex thickness and retinal nerve fiber layer thickness were compared among normal controls, POAG and NTG subjects. Additionally, the factors influencing choroidal thickness (age, axial length, spherical equivalent, central corneal thickness, mean deviation, nocturnal dip, blood pressure variability) were analyzed. RESULTS: A total of 32 normal controls, 32 POAG and 52 NTG patients were enrolled in this study. Macular and peripapillary choroidal thicknesses were significantly thinner in the NTG patients. In NTG subjects, the significant influencing factors associated with macular and peripapillary choroidal thicknesses were age, axial length, nocturnal dip (diastolic blood pressure), diastolic blood pressure variability and ganglion cell complex thickness. In POAG patients, significant influencing factors associated with macular and peripapillary choroidal thicknesses were age and axial length. CONCLUSIONS: Choroidal thickness was significantly thinner in NTG patients compared with normal controls and POAG patients. Factors influencing choroidal thickness in NTG patients were age, axial length, nocturnal dip (diastolic blood pressure), diastolic blood pressure variability and ganglion cell complex thickness. In POAG patients, significant factors influencing choroidal thickness were age and axial length.
Blood Pressure
;
Choroid*
;
Ganglion Cysts
;
Glaucoma, Open-Angle*
;
Humans
;
Low Tension Glaucoma
;
Nerve Fibers
;
Retinaldehyde
;
Retrospective Studies
;
Tomography, Optical Coherence
3.A Case of Internalization of Thracoamniotic Shunt of Fatal Bilateral Chylothorax.
Soo Pyung KIM ; Jong Chul SHIN ; Sa Jin KIM ; Seung Hye RHO ; Gui Se Ra LEE ; Seung Gyu SONG ; Yong Suk LEE ; Hae Gyu LEE ; Yoon Kyung CHOI
Korean Journal of Perinatology 1998;9(4):429-433
Using 3D ultrasound, bilateral chylothorax was diagnosed antenatally in the second trimester. Apparently stable, bilateral pleural effusion progressed rapidly to severe hydrops with facial edema during observation, and then we decided bilateral pleural-amniotic shunt operation. Here we present a case where drainage of pleural effusion by a double reverse pig tail stent made by ourself was achieved, although placement of the thoracoamniotic shunt resulted in near complete drainage of bilateral pleural effusion with normalization of intrathoracic anatomic relationships, subsequent resolution of fetal hydrops, but the ultimate outcome was unsuccessful due to the internalization of one catheter and unknown sudden death. We think that ongoing research is required to further evaluation about complications associated with this procedure, specifically failure of function due to obstruction, migration of the catheter,
Catheters
;
Chylothorax*
;
Death, Sudden
;
Drainage
;
Edema
;
Female
;
Humans
;
Hydrops Fetalis
;
Pleural Effusion
;
Pregnancy
;
Pregnancy Trimester, Second
;
Stents
;
Tail
;
Ultrasonography
4.Utility of measurement of GFR using 99mTc-DTPA in patients with increased ECF volume.
Chang Ho JEONG ; Yong Jun YU ; Jeong Eun KIM ; Seung Ik RHO ; Du Seon SEO ; Yoon Kwon KIM ; Chong Soon KIM ; Seung Soo HAN
Korean Journal of Medicine 1993;45(6):744-750
No abstract available.
Humans
5.The Significance of Measurement of Mullerian Inhibiting Substance in Neonates with Respiratory Distress Syndrome.
Soo Pyung KIM ; In Kyung SUNG ; Seung Hye RHO ; Hee Kyung LIM ; Myung Jae PARK ; Jae In SIN ; Byung Gyu SEO ; Jang Heub KIM
Korean Journal of Perinatology 1998;9(2):111-119
OBJECTIVE: The objectives of this study were to obtain information on MIS levels in normal and RDS neonates and to investigate the relationship between the RDS prevalence and MIS level in preterm and term neonates. METHODS: Total 131 male neonates were selected randomly and they were consisted of 50 term normal neonates, 15 term neonates with RDS, 50 prematurely born normal neonates, and 16 prematurely born neonates with RDS. Total 131 female neonates were also selected like male neonates. The venous blood was collected from all subjects and measured the level of MIS using ELISA. The ANCOVA was conducted to evaluate any influence of adjusted value of gestational age and body weight on MIS level between normal neonates and neonates with RDS. RESULTS: 1) The MIS levels of female neonates were significantly lower than those of male neonates with no overlap. 2) The MIS levels of normal female neonates were not significantly different from those of female neonates with RDS. 3) There were significant negative relationships between MIS concentration and gestational age (r=-0.777, p<0.001), and birth weight(r=-0.728, p<0.001) in normal rnale neonates. 4) There were significant negative relationships between MIS concentration and gestational age (r=-0.726, p<0.001), and birth weight(r=-0.725, p<0.001) in male neonates with RDS. 5) After adjusting the value of gestational age, the MIS level of male neonates with RDS was significantly higher than that of normal male neonates(p<0.001). 6) After adjusting the value of body weight, the MIS level of male neonates with RDS was significantly higher than that of normal male neonates(p<0.001). CONCLUSION: Male neonates with RDS had higher MIS levels than normal male neonates of the same body weight or same calculated gestational age. The results of this study suggest that MIS may play a causative or important ancillary role in the sexual dimorphism that characterizes the neonatal RDS and may be used as a predictive marker of RDS in male neonates.
Anti-Mullerian Hormone*
;
Body Weight
;
Enzyme-Linked Immunosorbent Assay
;
Female
;
Gestational Age
;
Humans
;
Infant, Newborn*
;
Male
;
Parturition
;
Prevalence
6.A case of Benign Cystic Peritoneal Mesothelioma in a Male Fetus.
Hyun Sun KO ; Dae Ho KANG ; Jee Hyun LEE ; Hee Bong MOON ; Seung Hye RHO ; Eun Jung BAIK ; Dae Young CHUNG ; Jong Chul SHIN ; Soo Pyg KIM
Korean Journal of Obstetrics and Gynecology 2000;43(10):1879-1883
No abstract available.
Fetus*
;
Humans
;
Male*
;
Mesothelioma*
7.Clinical Experience of Malignant Fibrous Histiocytoma in Maxillary Sinus.
Seung Oh HAN ; Seok Chan EUN ; Suk Joon OH ; Young Soo RHO
Journal of the Korean Cleft Palate-Craniofacial Association 2002;3(1):93-97
Malignant fibrous histiocytoma is a connective tissue tumor containig fibroblast-like cells and histiocyte. It is one of the most common types of soft tissue sarcoma of late adult life but, the involvement of head and neck area is relatively rare. Although adequate modalities of treatment is performed, the prognosis of the tumor itself is not clear. Because of its highly malignant property and, as in cases of other regions of the body, devastating result would occur and aggressive treatment is required. Malignant fibrous histiocytoma shows variable histologic appearance, and may be classified into several subtypes(storiform- pleomorphic, myxoid, giant cell, inflammatory, angiomatoid) and the storiform-pleomorphic type is the most common type. The authors have recently experienced a case showing good clinical result to the present, after total maxillectomy and split thickness skin graft and postoperative radiotherapy(6400cGy) in the malignant fibrous histiocytoma involving the right maxillary sinus, so report this case with a review of literature.
Adult
;
Connective Tissue
;
Giant Cells
;
Head
;
Histiocytes
;
Histiocytoma
;
Histiocytoma, Malignant Fibrous*
;
Humans
;
Maxillary Sinus*
;
Neck
;
Prognosis
;
Sarcoma
;
Skin
;
Transplants
8.The Effect on Outcome of Amblyopia Treatment in Children with Anisometropic Amblyopia.
Seung Soo RHO ; Hong Seok YANG ; Yoon Hee CHANG ; Young Ju LEW ; Jong Bok LEE
Journal of the Korean Ophthalmological Society 2007;48(4):535-540
PURPOSE: To evaluate the factors affecting treatment outcome of children with anisometropic amblyopia. METHODS: We retrospectively investigated the treatment outcome of 57 children who were diagnosed as anisometropic amblyopia. The age at initial treatment, initial best corrected visual acuity of the amblyopic eye, amount and type of anisometropia, strabismus and compliance of treatment were investigated. RESULTS: The mean age and standard deviation at initial treatment was 5.3+/-1.8(3-9) years. The absolute average values of spherical and cylindrical anisometropia were 2.87+/-1.99D and 1.87+/-2.24D respectively. While compliance was significantly related to treatment outcome, the age at initial treatment, visual acuity on amblyopic eye, amount and type of anisometropia, and strabismus had no significant influence on treatment outcome. CONCLUSIONS: Treatment compliance was the most significant factor in the treatment of anisometropic amblyopia.
Amblyopia*
;
Anisometropia
;
Child*
;
Compliance
;
Humans
;
Retrospective Studies
;
Strabismus
;
Treatment Outcome
;
Visual Acuity
9.The Antimydriatic Effect of Brimonidine 0.15% on the Dark-adapted Pupil in Dark Brown Irides.
Seung Soo RHO ; Hong Seok YANG ; Ho Min LEW ; Jae Hong AHN
Journal of the Korean Ophthalmological Society 2008;49(10):1649-1657
PURPOSE: To analyze the effect of the daily use of brimonidine tartrate 0.15% on the dark-adapted pupil diameter in dark brown irides. METHODS: Twenty-five healthy volunteers administered brimonidine tartrate 0.15% to their right eyes once daily for 3 weeks. Infrared digital photographs of the pupil were taken before administration and 1 hour and 4 hours after administration after dark adaptation (at <0.1 lux ambient illumination for 5 minutes). The diameters of both pupils were measured on the first day, on administration days 7 and 21, and on washout day 7. RESULTS: Four hours after the first administration, pupils showed a decrease of 0.95+/-0.74 mm, 1.03+/-0.94 mm, 0.61+/-0.85 mm on the first day, administration day 7, and administration day 21, respectively (p<0.01), compared with baseline data. The anti-mydriatic effect of brimonidine was sustained for 3 weeks, but the proportions of the eyes showing a reduction in pupil diameter by 0.5 mm or more were 84%, 76%, 68%, and 52% at 4 hours on the first day, administration days 7 and 21, and washout day 7, respectively. CONCLUSIONS: The anti-mydriatic effect of the daily use of brimonidine 0.15% on dark brown irides in a scotopic condition is maintained during the instillation period but has a tendency to fade over time. This point should be considered when using this compound as a miotic agent.
Dark Adaptation
;
Eye
;
Lighting
;
Pupil
;
Quinoxalines
;
Brimonidine Tartrate
10.Temporal response of ovine fetal plasma erythropoietin induced by fetal hemorrhage.
Sa Jin KIM ; Robert A BRACE ; Gui Se Ra LEE ; Seung Hye RHO ; Jong Chul SHIN ; Dae Young JUNG ; Young YI ; Jin Woo KIM ; Soo Pyoung KIM
Korean Journal of Obstetrics and Gynecology 2000;43(3):457-460
OBJECTIVE: The ovine fetus responds to hemorrhage with a 10-20 fold increase in plasma erythropoietin (EPO) concentration at 24 hr and a return toward normal at 48 hr after the hemorrhage. The objective of the present study was more accurately to compare the magnitude and time course of the plasma EPO response after fetal hemorrhage. METHODS: Chronically catheterized, 12 of late gestation ovine fetus were gradually hemorrhaged 40% of their blood volume over 2 hr (1ml/min). Plasma was sampled for EPO concentration at 1, 2, 3, 4, 6, 8, 10, 12, 16, 20, 24, 30, 36 hr after initiating the hemorrhage were collected at these times. Radioimmunoassay was used to measure plasma EPO concentrations. Analysis of variance was used for statistical analysis. RESULT: After a slow hemorrhage in the ovine fetus (1ml/min over 2hr), plasma EPO concentration increased significantly at 4hr (2.3 times basal values), reached a maximum at 16 hr (33.3 times basal values), and declined thereafter. CONCLUSION: We studied change in time course of the fetal plasma EPO after slow hemorrhage and recent studies have shown that the fetal kidney, liver and placenta express EPO mRNA. These observation suggest that plasma EPO increase may be mediated by a tissue specific up-regulation of EPO transcription in the fetal kidney, liver and placenta. We have studied change in Epo mRNA expression in various fetal tissue after slow haemorrhage.
Blood Volume
;
Catheters
;
Erythropoietin*
;
Fetus
;
Hemorrhage*
;
Kidney
;
Liver
;
Placenta
;
Plasma*
;
Pregnancy
;
Radioimmunoassay
;
RNA, Messenger
;
Sheep
;
Up-Regulation