1.Dopamine-2 and serotonin-2 receptor bindings in antipsychotic medicines from natural products.
In Won CHUNG ; Seung Ryul KIM ; Eung Gook KIM
Journal of Korean Neuropsychiatric Association 1992;31(5):856-868
No abstract available.
Biological Products*
2.A case of peritonitis following colonoscopy in patient on continuous ambulatory peritoneal dialysis.
Hee Seung HONG ; Seung Joon SHIN ; Byung Geun HAN ; Seung Ryul KIM ; Seung Ok CHOI ; Kwang Hoon LEE ; Hyang In KIM
Korean Journal of Nephrology 1993;12(4):711-714
No abstract available.
Colonoscopy*
;
Humans
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Peritoneal Dialysis, Continuous Ambulatory*
;
Peritonitis*
3.Quantification of human urinary growth hormone and its clinical significance in the diagnosis of growth hormone deficiency.
Seung Ryul LEE ; Ho Seong KIM ; Duk Hi KIM ; Chang Mi KIM
Journal of the Korean Pediatric Society 1992;35(5):595-601
No abstract available.
Diagnosis*
;
Growth Hormone*
;
Humans*
4.Hot spleen in hemochromatosis.
Yun Keun LIM ; Sung Ryul KIM ; Hee Seung BOM ; Ji Yeul KIM
Korean Journal of Nuclear Medicine 1991;25(2):298-299
No abstract available.
Hemochromatosis*
;
Spleen*
5.A Comparison of using Interlocking IM Nail versus Plate Fixation in Humeral shaft fractures
Do Yung KIM ; Joo Ho SHIN ; Hwa Jae JEONG ; Eui Tak CHU ; Seung Ryul LUM
The Journal of the Korean Orthopaedic Association 1995;30(3):709-716
The tibial pilon fracture has been described as difficult fracture to manage. We have reviewed 23 cases of tibial pilon fractures from Mar. 1987 to Feb. 1993 at our hospital. 1. The fractures were classified into five types according to the system of Ovadia and Beals and the methods of treatment were divided into two groups; 9 cases were treated with Ilizarov device(Group I). 6 cases out of Group I were type 3, 4 and 5. Other methods were performed in 14 cases(Group II). 8 cases out of Group II were type 3, 4, and 5. 2. In type 3, 4 and 5 fractures, there were 86 per cent good and fair radiographic results in Group I and 63 per cent good and fair results in Group II. 3. Satisfactory results were obtained by the treatment of Ilizarov method especially in type 3, 4 and 5 fractures. The advantages of Ilizarov device were its primary reduction with ligamentotaxis, easy open reduction due to proximal and distal stabilization, minimal soft tissue injury and minimal internal fixation.
Ilizarov Technique
;
Soft Tissue Injuries
6.QT and RR interval variability and spectral characteristics in response to physiologic autonomic stimulation.
Kwang Seung SHIN ; Myung Kul YUM ; Nam Su KIM ; Chang Ryul KIM ; Chung Ill NOH ; Hee Su KIM
Korean Circulation Journal 2000;30(12):1507-1514
Purpose: The purposes of this study were to compare the magnitude and phase between the RR interval and QT interval variability in the frequency domain. METHODS: Twenty four, 12-13 year old healthy males were randomly selected. At resting state and for 5 minutes, ECGs were obtained, and they were digitized to 1000Hz. After measurement of RR interval, QT interval variability was measured using template matching strategy. After normalization of the RR and QT interval time series, power spectral and cross spectral analysis were performed. From each of the time series, low- (0.04-0.15 hertz) and high- (0.15-0.4 hertz) frequency power were measured. From the phase spectrum, the phases and time lags between the two time series at each of the two frequency range were calculated. RESULTS: The average of RR interval and QT interval was 616.0+/-71.0, 364.0+/-47.0 msec, respectively. Their normalized low- and high- frequency power was 4.4+/-7.9 NU(normalized unit), 0.1+/-0.1 NU(p<0.005), and 11.0+/-30.0 NU, 0.3+/-0.3(NU, p<0.005), respectively. The phase differences and resulting time lags between the two interval were -0.5+/-0.4 pi radian(-0.9 seconds) and -0.2+/-0.3 pi radian(-0.4 seconds) in the low- and high-frequency range, respectively. CONCLUSION: During resting state, when compared to RR interval, QT interval oscillates in significantly lower amplitude in both low- and high- frequency ranges. However, the oscillations precede those of the RR interval 0.9 seconds and 0.4 seconds, respectively.
Electrocardiography
;
Humans
;
Male
7.Three Cases of Dieulafoy's Disease.
Kun Ho YANG ; Seoung Ryul KIM ; Hee Seung BOM ; Suk Bin KIM ; Il Chong PARK ; Chong Mann YOON
Korean Journal of Gastrointestinal Endoscopy 1986;6(1):27-30
Dieulafoys lesion consists of abnormally large gastric submucosal artery which ruptures into the stomach causing massive or recurrent intragikstric bleeding. The lesion is very small and easily overlooked even at laparatomy and aan only be correctly diagnosed by endoscopy or arteriography if the patient is actively bleeding. Three patients who were admitted with bleeding of upper gastrointestinal tract and eventually diagnosed as having Dieulafoys lesions were analysed. All were men with age range of 44 to 55 years. All patient were asymptomatic before presenting with hematemesis. Two of the three patients had had history of upper Gl bleeding. One patient used analgesics daily for ureteral colic and two patient drank alcohol excessively. Gastroscopy was performed during the bleeding episode in all three patients. Dieulafoy's lesion was seen in all three cases and in the second case, there was concomittent diffuse petechia in the whole stomach. The lesion was situated on the posterior wall of upper body in one, on anterior wall of upper body in another, lesser curvature side of gastric fundus in the other case. All three patient underwent laparotomy for persistent bleeding and the lesion was suture ligated only in two patients while in one patient vagotomy and pyloroplasty was added. Resection biopsy was performed in two cases and both revealed only normal gastric mucosa. All patients discharged after complete recover.
Analgesics
;
Angiography
;
Arteries
;
Biopsy
;
Endoscopy
;
Gastric Fundus
;
Gastric Mucosa
;
Gastroscopy
;
Hematemesis
;
Hemorrhage
;
Humans
;
Laparotomy
;
Male
;
Renal Colic
;
Rupture
;
Stomach
;
Sutures
;
Upper Gastrointestinal Tract
;
Vagotomy
8.Muscular System of Depressor Septi Nasi: Anatomical Study and Clinical Application.
Jae Yong JEONG ; Sang Ha OH ; Seung Ryul LEE ; Nak Heon KANG ; Dong Woon KIM
Journal of the Korean Society of Aesthetic Plastic Surgery 2009;15(1):49-54
Hyper-activated depressor septi nasi is an important factor caused a nasal tip drooping and many studies have been carried out, however it still remains controversial. This study presents a surgical modality for its intervention, based on the anatomical study. Eleven fixed and six fresh cadavers were used for the study. We found that the depressor septi nasi was consisted of three fascicles. Medial fascicles were inserted into the dermocartilaginous ligament, and deep fibers of the medial fascicles were attached to the anterior nasal spine. After superficial fibers were interdigitated with the orbicularis oris, they were attached to the alveolar bone. Intermedial fascicles were inserted to the footplates of the medial cruses and the caudal septum. After they were interdigitated with the medial fascicle and the orbicularis oris, they were attached to the alveolar bone. From April to August 2008, five patients had surgical intervention for hyper-activated depressor septi nasi. Medial and intermedial fascicles were detached completely from the anterior nasal spine and the septum through intranasal approach. Tip droopings were improved in all cases. Specific complications were not found. We believe that surgical intervention through intranasal approach is a useful method for correction of tip drooping.
9.Hypoxia Increases β-Cell Death by Activating Pancreatic Stellate Cells within the Islet
Jong Jin KIM ; Esder LEE ; Gyeong Ryul RYU ; Seung-Hyun KO ; Yu-Bae AHN ; Ki-Ho SONG
Diabetes & Metabolism Journal 2020;44(6):919-927
Hypoxia can occur in pancreatic islets in type 2 diabetes mellitus. Pancreatic stellate cells (PSCs) are activated during hypoxia. Here we aimed to investigate whether PSCs within the islet are also activated in hypoxia, causing β-cell injury. Islet and primary PSCs were isolated from Sprague Dawley rats, and cultured in normoxia (21% O2) or hypoxia (1% O2). The expression of α-smooth muscle actin (α-SMA), as measured by immunostaining and Western blotting, was used as a marker of PSC activation. Conditioned media (hypoxia-CM) were obtained from PSCs cultured in hypoxia. Islets and PSCs cultured in hypoxia exhibited higher expressions of α-SMA than did those cultured in normoxia. Hypoxia increased the production of reactive oxygen species. The addition of N-acetyl-L-cysteine, an antioxidant, attenuated the hypoxia-induced PSC activation in islets and PSCs. Islets cultured in hypoxia-CM showed a decrease in cell viability and an increase in apoptosis. PSCs within the islet are activated in hypoxia through oxidative stress and promote islet cell death, suggesting that hypoxia-induced PSC activation may contribute to β-cell loss in type 2 diabetes mellitus.
10.Lung Transplantation for Chronic Humidifier Disinfectant-Associated Lung Injury.
Won Young KIM ; So Woon KIM ; Kyung Wook JO ; Sae Hoon CHOI ; Hyung Ryul KIM ; Yong Hee KIM ; Dong Kwan KIM ; Seung Il PARK ; Sang Bum HONG
Korean Journal of Critical Care Medicine 2016;31(2):146-151
In the spring of 2011, a cluster of lung injuries caused by humidifier disinfectant (HD) usage were reported in Korea. Many patients required mechanical ventilation, extracorporeal membrane oxygenation, and even lung transplantation (LTPL). However, the long-term course of HD-associated lung injury remains unclear because the majority of survivors recovered normal lung function. Here we report a 33-year-old woman who underwent LTPL approximately four years after severe HD-associated lung injury. The patient was initially admitted to the intensive care unit and was supported by a high-flow nasal cannula. Although she had been discharged, she was recurrently admitted to our hospital due to progressive lung fibrosis and a persistent decline in lung function. Finally, sequential double LTPL was successfully performed, and the patient's clinical and radiological findings showed significant improvement. Therefore, we conclude that LTPL can be a therapeutic option for patients with chronic inhalation injury.
Adult
;
Catheters
;
Disinfectants
;
Extracorporeal Membrane Oxygenation
;
Female
;
Fibrosis
;
Humans
;
Humidifiers*
;
Inhalation
;
Inhalation Exposure
;
Intensive Care Units
;
Korea
;
Lung Injury*
;
Lung Transplantation*
;
Lung*
;
Oxygen Inhalation Therapy
;
Respiration, Artificial
;
Survivors