No abstract available.

No abstract available.
Aneurysm* ; Humans ; Hydrocephalus*

No abstract available.

No abstract available.

No abstract available.
Spinal Cord Vascular Diseases*

To overcome the difficulty of controlling stem cell fate and function in applications to regenerative medicine, a number of alternative approaches have been made. Recent reports demonstrate that a non-cellular niche modulating the biophysical microenvironment with chemical factors can support stem cell self-renewal. In our previous studies, early establishment was executed to optimize biophysical factors and it was subsequently found that the microgeometry of the extracellular matrix made huge differences in stem cell behavior and phenotype. We review here a three-dimensional, non-cellular niche designed to support stem cell self-renewal. The characteristics of stem cells under the designed system are further discussed.
Extracellular Matrix ; Phenotype ; Regenerative Medicine ; Stem Cells

No abstract available.

Sixteen consecutive patients with lumbar spondylolisthesis were treated with pedicular fixation and posterior interbody fusion. There were 8 isthmic and 8 degenerative types ranging in age from 39 to 68 years with a mean age of 52 years. The percentage of slippage averaged 28.5% preoperatively and 5.8% postoperatively in the isthmic type, 12.6% preoperatively and 6.6% postoperatively in the degenerative type. At 6 to 13 months postoperatively, all exhibited radiographic fusion. Clinical results were good in 13/16, fair in 3/16.
Humans ; Spondylolisthesis*

PURPOSE: The difference in the values between autorefraction and clinical refraction with or without cycloplegia in children were analyzed as a function of age. METHODS: One hundred and twenty five children (230 eyes) with myopia or hyperopia were classified into three age groups. Their ages ranged from 2 to 14. They were examined with a Cannon RK-5 autorefractor, and experienced personnel the clinical refraction before and after cycloplegia. Discrepancies beyond 0.5 diopter in spherical equivalent, spherical and cylinder power were regarded as being significant and the discrepancy rates (%) were calculated. The mean absolute differences in the values of each refractive component in myopia and hyperopia were also compared separately according to. RESULTS: All the differences by cycloplegia were significantly smaller in the myopia patients over 5 years old. However, only the discrepancy rates of the spherical equivalent and the sphere component between the clinical manifest refraction and the cycloplegic refraction were significantly smaller in the higher age groups. The comparisons between the clinical and autorefraction revealed significant difference between the age groups only in those with myopia with cycloplegia. CONCLUSIONS: There were differences between the cycloplegic refraction and non-cycloplegic refraction values particularly in myopia patients under five years old and in all hyperopic patients. Autorefraction showed differences from the clinical refraction in both myopia and hyperopia regardless of their ages particularly in those without cycloplegia. Therefore, autorefraction and clinical refraction should be used with caution in children.
Child* ; Child, Preschool ; Humans ; Hyperopia ; Myopia

The implatnation of malignant cells along the needle tract is an extremely rare complication after a percutaneous fine-needle aspiration biopsy(FNAB). However, it is very serious and may result in a change in the prognosis of lung cancer, especially in the curable early stage(T1-2,N0,M0). Recently, we experienced two cases of such complications. A 43 years old female underwent a fine needle aspiration biopsy and a right middle lobectomy with adjuvant chemotherapy due to an adenocarcinoma(T2N0M0). Two years later, a new tumor developed at the site of the needle aspiration biopsy. It had the same pathological findings as the previous lung cancer. Therefore, it was concluded to be an implantation metastasis, and she was treated successfully by a right pneumonectomy and a resection of the chest wall mall with adjuvant radiotherapy. In another case, a 62 years old man was diagnosed with squamous cell lung cancer by a fine needle aspiration biopsy and underwent a right upper lobectomy(T2N0M0) with adjuvant chemotherapy. eight months later, a protruding chest wall mass developed at the aspiration site. It showed the same pathological findings as the previous lung cancer. Consequently, a total excision of the mass with adjuvant radiotherapy was done. Two years after the second operation, although the right lung was intace a metachronous squamous cell lung cancer was found at the left lower lobe. The two patients were still alive 15 and 37 months after thenresection of the chest wall mass, respectively.
Biopsy ; Biopsy, Fine-Needle* ; Biopsy, Needle ; Chemotherapy, Adjuvant ; Female ; Humans ; Lung Neoplasms* ; Lung* ; Needles ; Neoplasm Metastasis* ; Pneumonectomy ; Prognosis ; Radiotherapy, Adjuvant ; Thoracic Wall* ; Thorax*