1.A study of mycology and cultural method in onychomycosis.
Seung Yong KIM ; Byoung Soo CHUNG ; Kyu Cherl CHOI
Korean Journal of Dermatology 1991;29(1):50-55
This mycological and cultural investigation was made in 86 cases of onychomycosis diagnosed on positive KOH wet mount at Chosun University Hospital from October, 1989 to February, 1990. The results were as follows : l. The ratio of male to female was 1.2:1. According to Zaiass classificat.ion, distal subungual onychomycosis (DSO) was the most predominant type(79 cases) and others, in decreasing frequency, were superficial white onychomycosis (SWO) (Fcases), total dyst,rophic onychomycosis (TDO) (1 cases, and proximal subungual onychomycosis (PSO) was not. found. 2. In DSO, isolat,ed fungi were T. mentagrophyte(31 cases), "i'. rubrum(23 c
Female
;
Fungi
;
Humans
;
Male
;
Mycology*
;
Onychomycosis*
2.Gross and Microscopic Findings of the Testes Ascended into abdomen During Neonatal and Prepubertal age in Rats.
Woong Kyu HAN ; Seung Eon LEE ; Sang Won HAN ; Seung Kang CHOI ; Tack LEE
Korean Journal of Urology 2001;42(1):10-15
PURPOSE: Because cryptorchid testes are known to undergo histopathologic changes affecting development, maturation, and tertility, early surgical correction is usually recommended. However there are differing opinions concerning whether retractile testes are affected by similar changes and also whether there is a need for surgical treatment. We aimed to assess the histopathologic changes in retractile testis by studying the changes in testes artificially placed back in the abdomen after they have descended to scrotum in experimental rat models. MATERIALS AND METHODS: Male Sprague-Dawley rats were divided into 3 groups; a control group(controls), prepubertal ascent group (P) in which testis were placed back intraabdominally by bilateral inguinal canal obstruction at 6 weeks, a neonatal group(N) in which intraabdminal testis was induced by bilateral inguinal canal obstruction at birth. The relative weight of the testis, morphology of the seminiferous tubules including Leydig cells, tubular degeneration phase(TDP), spermatogonia per tubules(S/T), and Sertoli cell index (SCI) of these three groups were analyzed and compared. RESULTS: The relative weight of testis was significantly decreased in the group of N(0.0016+/-0.001) and P(0.0015+/-0.0002) compared to controls(0.0037+/-0.0002) (p<0.05). The S/T value was also decreased in P(2.05+/-18.2) and N(73.2+/-32.4) when compared to controls (360.2+/-21.3). Similar changes were observed in SCI of both P(64.5+/-6.4) and N (91.2+/-14.2) when compared to controls (227.9+/-31.1). Only minority of N and P showed higher TDP values. However, although statistically insignificant, TDP was increased in both P and N when compared to controls. The Leydig cells in N and P showed cellular distortion and hypertrophy. CONCLUSIONS: This study demonstrate that prepubertal ascent, similar to that of innate cryptorchid testis, also can induce histopathologic changes such as changes in testicular seminiferous tubule, decrease in the S/T value and decrease in SCI value. Our findings supports that hypothesis that retractile testis may cause histological damage thus surgical correction may also be warranted similar to in case of genuine cryptorchism.
Abdomen*
;
Animals
;
Cryptorchidism
;
Humans
;
Hypertrophy
;
Inguinal Canal
;
Leydig Cells
;
Male
;
Models, Animal
;
Models, Theoretical
;
Parturition
;
Rats*
;
Rats, Sprague-Dawley
;
Scrotum
;
Seminiferous Tubules
;
Spermatogonia
;
Testis*
3.Prognostic Value of Somatosensory Evoked Potentials in Comatose Patients after Cardiopulmonary Resuscitation.
Se Min CHOI ; Dong Rul OH ; Seung Pil CHOI ; Kyu Nam PARK ; Se Kyung KIM
Journal of the Korean Society of Emergency Medicine 2000;11(4):450-456
BACKGROUND: The improved technique for cardiopulmonary resuscitation(CPR) has resulted in the survival of many patient who experienced cardiac arrest. However, mortality in resuscitated patients is high, and the survival rate without brain damage is very low. Various neurological examination models, neuro-imaging techniques, electrophysiological procedures, and biochemical tests have been studied with respect to the detection of cerebral damage and outcome, but an early, reliable prediction of individual outcomes is still uncertain. METHODS: We studied twenty patient who had been in a coma for more than 24 hours after CPR, Somatosensory evoked potentials(SEP) were measured within the first three days after CPR. RESULTS: Of the twenty patients, seven patients(35%) had a good outcome, and thirteen patients(65%) had a bad outcome. Of the eleven patients with loss of the cortical evoked potential's N20 peak, all had a bad outcome. CONCLUSION: SEPs are of great benefit in prognostic evaluation after CPR.
Brain
;
Cardiopulmonary Resuscitation*
;
Coma*
;
Evoked Potentials, Somatosensory*
;
Heart Arrest
;
Humans
;
Mortality
;
Neurologic Examination
;
Survival Rate
4.Association of Alcohol Dependence with the Dopamine Transporter Gene Polymorphism.
Yun Jeong CHOI ; Seung Kyu BANG ; Jung JIN ; Kyu Young TOH ; In Ho PAIK
Journal of Korean Neuropsychiatric Association 1999;38(4):826-833
OBJECTIVES: Alcoholism is known to be a heritable disease. It has been hypothesized that dopamineergic systems play an important heritable role in human behavor related to alcohol dependence, such as alcohol seeking. Therefore, genes involved in this pathway, including dopamine transporter(DAT1) which is responsible for taking released dopamine back up into presynaptic terminals and terminating dopaminergic activity, are potential candidate that may affect susceptibility to alcoholism. Analysis of a 40-base pair(bp)repeat(VNTR)in the 3'untranslated region of the DAT1 gene revealed variable number of the repeat ranging from 3 to 11 copies. Therefore, in the present study, we examined the association between alcoholism and VNTR polymorphism of DAT1. METHODS: Genomic DNA analysis with polymerase chain reaction(PCR)was used to identify the presence of a VNTR polymorphism. It was carried out within a group of 94 alcoholic patients and 113 normal controls. RESULTS: 1)There were no significant differences in allelic or genotype frequencies between the group of alcoholic patients and controls. 2)There were no significant differences in the first drinking age, onset age and latency of alcoholism according to DAT1 genotypes. 3)There was a significant difference in allelic frequencies between alcoholics with family history and those without family history. CONCLUSIONS: These results suggested that VNTR polymorphism of DAT1 is unlikely to be a factor in the genetic etiology of alcoholism, but might be related to familial transmission of alcoholism.
Age of Onset
;
Alcoholics
;
Alcoholism*
;
DNA
;
Dopamine Plasma Membrane Transport Proteins*
;
Dopamine*
;
Drinking
;
Genotype
;
Humans
;
Presynaptic Terminals
5.A Case of Mayer-Rokitansky-K ster-Hauser Syndrome combined with Unilateral Renal Agenesis and Pelvic Cystic Mass in Child.
Woong Kyu HAN ; Chul Kyu CHO ; Sang Won HAN ; Seung Kang CHOI
Korean Journal of Urology 1999;40(6):799-802
The Mayer-Rokitansky-K ster-Hauser syndrome represents a spectrum of m llerian anomalies, including vaginal agenesis with or without renal anomalies, in genotypically and phenotypically normal female subjects with normal endocrine status. We experienced a case of this anomaly which combined with unilateral renal agenesis and pelvic cystic mass in child.
Child*
;
Female
;
Humans
6.Transcervical GIFT & ZIFT by tactile sensation.
Young Bum CHA ; Jong Min PARK ; Seung Jae LEE ; Kyu Wan CHOI ; Hyun Won YANG ; Hee Kyu KANG
Korean Journal of Obstetrics and Gynecology 1993;36(5):634-639
No abstract available.
Sensation*
;
Zygote Intrafallopian Transfer*
7.Structural Evidence Against Hormonal Theraphy in Cryptorchid Testis-Abnormal Gubernacular Attachment.
Woong Kyu HAN ; Sang Won HAN ; Chul Kyu CHO ; Jang Hwan KIM ; Min Jong LEE ; Seung Kang CHOI
Korean Journal of Urology 2000;41(12):1528-1532
No abstract available.
8.Two Cases of Dyschromatosis Symmetrica Hereditaria.
Seung Yong KIM ; Dong Sik SHIN ; Byoung Soo CHUNG ; Kyu Chul CHOI
Korean Journal of Dermatology 1989;27(5):633-637
We report two cases of dyschromatosis symmetrica hereditaria. One is a 12-year- old female and her family had five individuals with similar pigmentary disorder through three generation. The other is a 22-yesr-old female who had no family history of similar disease. Fontana-Masson stain revealed increased and decreased melanin granules in the basal cell layers in the pigmented and depigmented lesions respectively.
Female
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Humans
;
Melanins
9.Fluid resuscitation in hemorrhagic shock model using 4% modified fluid gelatin(gelofusine) solution.
Ok Jun KIM ; Ok Kyung CHOI ; Seung Ho KIM ; Kyu Chang LEE ; Eui Ho HWANG
Journal of the Korean Society of Emergency Medicine 1991;2(1):70-79
No abstract available.
Resuscitation*
;
Shock, Hemorrhagic*
10.Modified Akira Yanai's method for correction of cryptotia.
Seung Keun BAEK ; Oh Kyu CHOI ; Jeong Jun PARK ; Jong Hyun LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1991;18(3):499-505
No abstract available.