1.Evaluation of Lipoprotein(a) as a Risk Factor for Coronary Artery Disease.
Hyun Young PARK ; Han Soo KIM ; Hyuck Moon KWON ; Yang Soo JANG ; Seung Yun CHO ; Hyun Seung KIM
Korean Circulation Journal 1993;23(4):542-548
Lipoprotein(a)[Lp(a)] is a LDL-like particle with a glycoprotein called apo(a) attached to its apoB through disulfide bond. Many case-control studies support the opinion that plasma Lp(a) levels were associated with coronary artery disease. This study was conducted to assess the relationship between plasma Lp(a) level and coronary artery disease in Korean population. Serum levels of Lp(a), in addition to other lipids and known clinical risk factors for coronary artery disease were determined in 92 subjects undergoing coronary angiography. Among them 30 patients had no obstruction in the coronary artery(cath-control group), while the others revealed the presence of coronary artery stenosis more than 50%(CAD group). The Lp(a) levels of the CAD group were significantly higher the those of cath-control group(31.8+/-25.0mg/dl vs 14.6+/-11.9mg/dl, p<0.005). Other lipids except triglycerides(166.9+/-70.5mg/dl vs 116.2+/-56.1mg/dl, p<0.005) were not significantly different between two groups. The patients with significant coronary artery disease of two or more vessels were found to have higher Lp(a) levels than those of one vessel disease. Lp(a) levels had no relations with other lipids, diabetes, smoking, hypertension and age. Stepwise discriminant analysis revealed that Lp(a) was the best discriminator among risk factors for coronary artery disease. These results suggested that Lp(a) level was a significant independent risk factor for coronary artery disease.
Apolipoproteins B
;
Case-Control Studies
;
Coronary Angiography
;
Coronary Artery Disease*
;
Coronary Stenosis
;
Coronary Vessels*
;
Glycoproteins
;
Humans
;
Hypertension
;
Lipoprotein(a)*
;
Plasma
;
Risk Factors*
;
Smoke
;
Smoking
2.Echophonocardiographic Study in Patients Undergoing Percutaneous Mitral Balloon Valvuloplasty(PMV).
Kyung Kwon PAIK ; Won Heum SHIM ; Yang Soo JANG ; Joon KWON ; Seung Jea TAHK ; Seung Yun CHO ; Sung Soon KIM ; Woong Ku LEE
Korean Circulation Journal 1990;20(1):89-97
Percutaneous mitral ballon valvuloplasty(PMV) is an effective nonsurgical procedure for patients with mitral stenosis. PMV was performed in 13 patients(mean age, 41 years) with mitral stenosis. All patients underwent echophonocardiography(Echophono) before and after PMV. Two dilatation balloons were used in which the diameters approximately equaled the mitral valve annulus diameter as determined. After PMV, the mean mitral valve pressure gradient decreased(22.3+/-1.89mmHg to 5.2+/-2.6mmHg), the mean left atrial pressure decreased(21.3+/-5.1mmHg to 9.0+/-4.5mmHg) and the mitral valve area increased from 0.8+/-0.3cm2 to 1.7+/-0.6cm2. The Echophono data are correlated with clinical and hemodynamic changes produced by PMV. PMV resulted in echophono changes consistent with decresed severity of mitral stenosis ; shortening of Q-S1, from 88+/-14 to 73+/-11 mses(p<0.01) and (Q-S1)-(S2-OS), from 0.9+/-1.7 to -2.1+/-1.6(p<0.001) ; prolongation of S2-OS from 80+/-15 to 103+/-14 msec(p<0.001) and increase of EF slope from 14.7+/-5.4 to 26.7+/-8.1 mm/sec(p<0.001). Compared with pre-PMV, post-PMV Echophono showed significant decrease in the severity of mitral stenosis. Thus Echophono is a simple, low cost method helpful in evaluation and follow-up patients undergoing PMV.
Atrial Pressure
;
Balloon Valvuloplasty
;
Dilatation
;
Follow-Up Studies
;
Hemodynamics
;
Humans
;
Mitral Valve
;
Mitral Valve Stenosis
3.Clinical Significance of Phase Analysis in Myocardial Infarction.
Hyun Seung KIM ; Je Yol OH ; Hyuck Moon KWON ; Yang Soo JANG
Korean Circulation Journal 1992;22(1):67-76
BACKGROUND: Evaluating the segmental wall motion of left ventricle is important in patients with myocardial infarction for choosing therapeutic modality and predicting prognosis. Radionuclide Multigated Angiography(MUGA) is a reliable noninvasive method for the evaluation of left ventricular performance. Methods : MUGA scan(LV ejection fraction, phase image histogram, regional wall motion) was performed and analyzed in 45 patients with myocardial infarction(31 : acute MI, 14: old MI) and 13 normal controls. RESULTS: 1) The LVEF of acute and old MI group was significantly reduced and the SDph of acute and old MI group was significantly increased as compared with that of control group(p<0.05). 2) In acute MI group, the LVEF of group without, IV Urokinase was more reduced than that of group with IV Urokinase and the SDph of group without IV Urokinase was more increased than that of group with IV Urokinase(p<0.05). As a result of wall motion scoring, the linear correlation exists between SDPh and sum of wall motion scoring(r=0.62, p<0.01). 3) In MI group, the LVEF of anterior wall MI was more reduced than that of inferior wall MI and the SDPh of anterior wall MI was more increased than that of inferior wall MI(p<0.05). 4) In acute anterior wall MI, the reverse correlation exists between LVEF and SDPh and the linear correlation exists between sum of wall motion scoring and SDPh(r=-0.73, 0.72, p<0.01). But there are no statistical significances of correlation between them in acute inferior MI(r=-0.44, 0.42, p>0.05), in old anterior MI(r=-0.65, 0.47, p>0.05) and in old inferior MI(r=-0.47, 0.46, P>0.05). CONCLUSION: These results suggest that Phase angle(SDPh) is thought to be valuable index to evaluate left ventricular function with application of other indeces in Myocardial infarction. Left ventricular function measured by SDph in acute or anterior MI is lower than old or inferior MI.
Heart Ventricles
;
Humans
;
Myocardial Infarction*
;
Prognosis
;
Urokinase-Type Plasminogen Activator
;
Ventricular Function, Left
4.Usefulness of Dipyridamole and Dobutamine Stress Echocardiography in Myocardial Infarction.
Sang Wook LIM ; Hyuck Moon KWON ; Yang Soo JANG ; Hyun Seung KIM
Korean Circulation Journal 1994;24(1):86-98
BACKGROUND: The dipyridamole and dobutamine stress echocardiography have been studied as a non-invasive diagnostic test in coronary artery disease. Recently, some authors have extended the usefulness of these tests to predicting the prognosis of myocardial infarction patients. But as far as we know, there was no literature which tried boh tests to the same infarcted patients group. So, we performed both tests in the 23 infarcted patients to compare and evaluate both tests as predicting the prognosis in myocardial infarction. METHODS: Patients underwent (1) two-dimensional echocardiography under basal condition and after dipyridamole infusion for 4 minites at the dose of 0.14mg/kg/min, (2) another two dimensional echocardiography under basal and during dobutamine infusion at each dose of 5 to a maximum of 20microg/kg/min at 1 or 2 days after dipyridamole stress echocardiography, and (3) coronary and left ventricular angiography. Preinfusion and peak infusion images were analyzed independently by two different observers using Nova Micro Sonic soft were(DataVueII and ColorVue II analysis system). The segmental wall motions were scored as follows ; hyperkinetic : 1, normal : 2, hypokinetic : 3, akinetic : 4. THe test response was considered positive if abnormal wall motion and reduced myocardial thickening were observed during drug infusion at the vascular distributions except the akinetic infarcted segment identified during basal condition. The coronary angiography was analyzed by measuring the maximal luminal diameter stenosis with caliper and 50% or greater diameter narrowing was considered significant. The sensitivity and specificity were calculated by comparing echocardiographic prediction and angiographic findings. RESULTS: 1) Among 22 patients with sufficient image in dipyridamole stress echocardiography, 13 patients have myltivessel coronary disease without resting akinesia of non-infarcted segments. Only 5 patients showed positive findings in dipyridamole stress echocardiography(sensitivity, 38.4%). Among 9 patients who has single or minimal disease, 9 patients were negative finding(specificity, 100%). 2) Among 21 patients with sufficient image in dobutamine stress echocardiography, 12 patients have multivessel coronary disease without resting akinesia of non-infarcted segments. 7 patients showed positive finding in dobutamine stress echocardiography(sensitivity, 58.3%). Among 9 patients who has single or minimal disease, 8 patients showed negative finding(specificity, 88.8%). 3) In hemodynamic changes, dipyridamole stress echocardiography showed significant changes in heart rates and double products and dobutamine stress echocardiography showed significant changes in heart rates, systolic blood pressure and double products. 4) There was no significant side effect during both stress tests inacute and old myocardial infarction patients. CONCLUSION: 1) The dobutamine and dipyridamole stress echocardiography are safe and easy test for myocardial infarction patients. 2) The dobutamine stress echocardiography has higher sensitivity than dipyrdamole stress echocardiography for identifying multivessel coronary disease in myocardial infarction patients but the dose of both drugs were relatively small to get the adequate results. So the high dose of drugs must be tried in feature study.
Angiography
;
Blood Pressure
;
Constriction, Pathologic
;
Coronary Angiography
;
Coronary Artery Disease
;
Coronary Disease
;
Diagnostic Tests, Routine
;
Dipyridamole*
;
Dobutamine*
;
Echocardiography
;
Echocardiography, Stress*
;
Exercise Test
;
Heart Rate
;
Hemodynamics
;
Humans
;
Myocardial Infarction*
;
Phenobarbital
;
Prognosis
;
Sensitivity and Specificity
5.The Factors Affecting Cultural Competency of Visiting Nurses and Community Health Practitioners.
Soon Ok YANG ; Myung Soon KWON ; Seung Hee LEE
Journal of Korean Academy of Community Health Nursing 2012;23(3):286-295
PURPOSE: The purpose of this study was to investigate the level of cultural competency of visiting nurses and community health practitioners and explore factors that are related with their cultural competency. METHODS: The subjects of this study were 113 visiting nurses and 103 community health practitioners working in Gangwon-do. Data were collected using a structured questionnaire on May 24, 2011. The SPSS/WIN 17.0 program was used for data analysis. RESULTS: The average score for cultural competency of visiting nurses was 2.76+/-0.60 and that of community health practitioners 2.91+/-0.51. Most of subjects received no multicultural education (78.0% for nurses, 85.7% for community health nurses). Factors influencing cultural competency were number of service experience for multicultural clients and participation of multicultural education. CONCLUSION: It is necessary to develop systematic educational programs to enhance the cultural competency of nurses.
Community Health Nursing
;
Cultural Competency
;
Surveys and Questionnaires
6.The treatment of involuntary inferior and multidirectional instability of the shoulder.
Kwon Ick HA ; Sung Ho HAHN ; Min Young CHUNG ; Bo Kyu YANG ; Seung Rim YI
The Journal of the Korean Orthopaedic Association 1992;27(7):1621-1629
No abstract available.
Shoulder*
7.A clinical study of segmental tibial fracture.
Chang Uk CHOI ; Jae Uk KWON ; Man Sik YANG ; Kwang Kon KO ; Seung Ryeol YOON
The Journal of the Korean Orthopaedic Association 1992;27(1):148-157
No abstract available.
Tibial Fractures*
8.Ultrasonographic findings of ovarian tumors
Yang Sook KWON ; Soo Han KIM ; Seung Hyup KIM ; Hyun Ja SHIN
Journal of the Korean Radiological Society 1986;22(5):906-911
The ultrasound is easily available and noninvasive diagnostic method without radiation hazard. We can approachto differential diagnosis of ovarian tumors by gray sale ultrasound which can display the detailed structure ofsoft tissue. In department of radiology, Korea Veterans Hospital, 27 cases of histologically confiremd ovariantumors collected from March 1984 to February 1986 were analized. The results were as follows: 1. The agedistribution was from 13 to 72 years. 2. The histologic diagnosis of ovarian tumors(27 cases) are as follows:teratoma(14), mucinous cystadenoma(8), mucinous cystadenocarcinoma(1), serous cystadenoma (2), Krukenburg tumor(1)and malignant thecoma (1). 3. The long diameter of ovarian tumors ranges from 4cm to 28cm. In these, mucinouscystadenoma is the largest and their size are as follows; less than 10cm; 25%, 11–15 cm; 12%, 16–20 cm; 25% andmore than 20cm; 38%. 4. The ultrasonographic findings of teratoma(14) were mainly cystic (8) or echogenic(6).There were echogenic solid components showing distal acoustic shadowing or fat-fluid level within cystic masses.Echogenecity of solid masses was heterogenous. 5. The ultrasonographic findings of mucinous cystadenoma&cystadenocarcinoma(9) were unilocular cystic (3) or multilocular cystic(6). There were variable amount ofechogenic component within cystic masses. 6. Those of serous cystadenoma(2) were unilocular cystic (1) ormultilocular cystic (1). 7. Krukenburg tumor(1) and Malignant thecoma(1) were heterogenously echogenic.
Acoustics
;
Commerce
;
Cystadenoma, Serous
;
Diagnosis
;
Diagnosis, Differential
;
Hospitals, Veterans
;
Korea
;
Methods
;
Mucins
;
Shadowing (Histology)
;
Thecoma
;
Ultrasonography
9.The Clinical Study on Ipsilateral Fracture of the Femur and Tibia
Chang Uk CHOI ; Byung Il LEE ; Jae Wook KWON ; Man Sik YANG ; Seung Kyu PARK
The Journal of the Korean Orthopaedic Association 1990;25(5):1333-1340
The "flosting knee" is the term applied to the flail knee joint segment resulting from a fracture of the shaft of adiacent metanhysis of the ipsilateralfemur and tibia. The various methods of treatment of the "floating knee" were adapted by many authors according to degree of the comminution, degree of the soft tissue injury, general condition state of the fracture. Authors experienced the floating knee in 52 cases on 51 patients who were treated at Soon Chun Hyang University Hospital in the period of 4 years and 5 months from January 1985 to June 1989 and among them, 45 cases were treated by operative method and 7 cases by conservative methods at least one of the femur and tibia, The results were as follews;1. Floating Knee occured six times more in male and the peak age was third and fourth decades. 2. The most common cause of fractures was traffie aecident and there was difficulty in diagnosis of ligamentous disruption of the ipsilateral knee. 3. The common fracture site were middle one third and the most common fracture shape was comminuted in both femur and tibia. 4. A good or excellent functional result was aohieved in treated with open reduction and rigid fixation of both fracture and there were no significant difference in group of the internal fixation of both femur and tibia. 5. Intramedullary nailing on the femur and plate fixation on the tibia provided rigid fixation of fracture and the it made possible early joint motion exercise and ambulation and the average healing time of fracuture was much shortened. 6. The most common concomitant injury were soft tissue injury and delayed or nonuion and osteomyelitis were developed more frequently in the plate and screw fixation group of the open fracture.
Clinical Study
;
Diagnosis
;
Femur
;
Fracture Fixation, Intramedullary
;
Fractures, Open
;
Humans
;
Joints
;
Knee
;
Knee Joint
;
Ligaments
;
Male
;
Methods
;
Osteomyelitis
;
Soft Tissue Injuries
;
Tibia
;
Walking
10.Sacral Spinal Meningeal Cyst(Perineurial Cyst): A Case Report.
Jun Seung LEE ; Yang Wha PARK ; Ik Seung KWON ; Youn Suok RYU ; Seung Kuan HONG ; Myong Sun MOON
Journal of Korean Neurosurgical Society 1989;18(4):634-638
We experienced a rare case of sacral meningeal cyst so called sacral perineurial cyst(Tarlov cyst). A 15 years old girl was admitted to the hospital because of sudden severe low back pain and Lt. sciatica for about one week. We performed delayed myelography and spinal computeized tomographic myelography(C.T.M) for differential diagnosis. Delayed filling of contrast media in the cyst was significant in diagnosis of sacral meningeal cyst type II. Laminectomy of sacrum(S1) was performed for partial excision of cystic wall and plastic suture. Operative finding was typical sacral perineurial cyst(Tarlov cyst) which was recently clssified as sacral meningeal cyst type II. The classification of spinal meningeal cysts in the literature was indistinct and confused. We also agree with Nabors et. al, in current classificcation of spinal meningeal cysts, in which the spinal meningeal cysts, in which the spinal meningeal cysts were divided into 3 groups as extradural spinal Mcs Type I(Diverticulum), Type II(perineurial cyst), intradural spinal Mcs(arachnoid cyst).
Adolescent
;
Classification
;
Contrast Media
;
Diagnosis
;
Diagnosis, Differential
;
Female
;
Humans
;
Laminectomy
;
Low Back Pain
;
Myelography
;
Plastics
;
Sciatica
;
Sutures