2.Oncologic Outcome of Chondrosarcomas.
Chol Jin KIM ; Jun Young CHUNG ; Yang Guk CHUNG ; Seung Koo RHEE ; Yong Koo KANG ; Won Jong BAHK ; Jung In SHIM
The Journal of the Korean Bone and Joint Tumor Society 2013;19(1):9-13
PURPOSE: We evaluated oncologic outcomes of chondrosarcomas and analyzed the disease-free survival rate of chondrosarcomas according to the various factors. MATERIALS AND METHODS: We performed a retrospective study for the disease-free survival rate of 48 chondrosarcomas, 44 of which underwent surgical treatment and followed up more than 18 months since 1993, and in the remaining 4 cases, the patients died before 18 months after surgery. The vsariables were location, tumor volume, histologic grade, stage, age at presentation and treatment performed. The mean follow up period was 43.8 months (1-196 months). RESULTS: The overall disease-free survival rate was 77.1% at mean 43.8 month follow up. The 5 year- and 10 year disease-free survival rates were 64% and 58% respectively. The histologic grade, stage, age at presentation revealed statistical significance on disease-free survival. All 9 patients treated with extended curettage for grade 1 central chondrosarcomas revealed disease-free survival with excellent functional outcome. CONCLUSION: The disease-free survival rate of chondrosarcomas mainly depended on histologic grade, stage and age at presentation. Local recurrence and distant metastasis also revealed statistically significant differences of disease-free survival rate. Comparing to wide resection, extended curettage for low-grade central chondrosarcomas in extremities were efficient methods with similar survival rate and less functional losses and complications.
Chondrosarcoma
;
Curettage
;
Disease-Free Survival
;
Extremities
;
Follow-Up Studies
;
Humans
;
Neoplasm Metastasis
;
Recurrence
;
Retrospective Studies
;
Survival Rate
;
Tumor Burden
3.Secondary Chondrosarcoma Arising from Osteochondroma(tosis).
Hyun min CHO ; Seung Koo RHEE ; Yong Koo KANG ; Yang Guk CHUNG ; An Hi LEE ; Jung Mi PARK ; Won Jong BAHK
The Journal of the Korean Bone and Joint Tumor Society 2010;16(1):21-26
PURPOSE: To analyze clinical, radiological and pathological features as well as clinical outcome after surgical treatment of patients with secondary chondrosarcoma arising from osteochondroma(tosis). MATERIALS AND METHODS: We retrospectively reviewed clinical records, radiographs, pathologic slides of 14 patients. Nine patients were male and five were female. The mean age was 34 years. The mean follow-up period was 54 months. RESULTS: All patients had a history of previous mass since childhood or puberty. Preexisted osteochondroma was single in 3 patients and multiple in 10. Remaining 1 patient had multiple osteochondromatosis with enchondromatosis. MRI clearly provided thickness of cartilage cap, which was over 2 cm except in 2 cases. Chondrosarcoma was grade 1 in all except 1 case, which was grade 2. Wide excision was performed in 10 patients, marginal excision in 3 and amputation in 1. Twelve patients were doing very well without evidence of disease. Among 3 patients with marginal excision, 1 patient had local recurrence and 1 patient died of disease. CONCLUSION: Comprehensive understanding of clinical, radiological and pathological features of secondary chondrosarcoma is warranted for accurate diagnosis. The best result can be expected with early recognition of malignant change of osteohcondroma(tosis) and wide excision.
Amputation
;
Cartilage
;
Chondrosarcoma
;
Enchondromatosis
;
Female
;
Follow-Up Studies
;
Humans
;
Male
;
Osteochondroma
;
Osteochondromatosis
;
Puberty
;
Recurrence
;
Retrospective Studies
4.Prognostic Factors in Liposarcomas: A Retrospective Study of 52 Patients.
Yang Guk CHUNG ; Yong Koo KANG ; Won Jong BAHK ; Seung Koo RHEE ; An Hi LEE ; Jung Mee PARK ; Min Woo KIM
The Journal of the Korean Bone and Joint Tumor Society 2010;16(1):14-20
PURPOSE: To investigate prognostic factors influencing on local recurrence, distant metastasis and event-free survival of liposarcomas. MATERIALS AND METHODS: Fifty-two patients managed for liposarcomas since 1993 were analyzed respectively in the view of prognostic influence of patient age, tumor size, location, histologic type, histologic grade, resection type, surgical margin, chemotherapy and radiation therapy on local recurrence, distant metastasis and event-free survival. The mean follow up period was 39 months. The univariate and multivariate regression analysis were performed for statistical evaluation. RESULTS: The local recurrences occurred in 11 patients (21.2%) and distant metastasis in 4 patients (8%), Event-free survival rate at 4 year follow up was 67%. In univariate analysis, histologic grade, surgical margin, chemotherapy and radiation therapy were significant prognostic factors on local recurrence (p<0.05). However, histologic grade lost its significance in muitivariate analysis. Trunk location revealed higher rate of distant metastasis than extremity location. In univariate analysis on event-free survival. histologic grade and chemotherapy were significant factors (p<0.05). No factor remained significant in multivariate analysis. CONCLUSION: Considering selection bias, positive surgical margin was negative prognostic factor on local recurrence. Liposarcomas arisen in trunk revealed higher rate of distant metastasis. There was no independent prognostic factor on event-free survival of patients with liposarcomas.
Disease-Free Survival
;
Extremities
;
Follow-Up Studies
;
Humans
;
Liposarcoma
;
Multivariate Analysis
;
Neoplasm Metastasis
;
Recurrence
;
Retrospective Studies
;
Selection Bias
5.Report of A Case of Renal Actinomycosis.
Jung Hoon YOON ; Seong Koo AHN ; Yoo Bock LEE ; Byung Ha CHUNG ; Seung Chul YANG
Korean Journal of Pathology 1986;20(3):383-387
Actinomycosis, in which the principal causative agent in man is known to Actinomyces israelii, is a chronic, suppurative diseases characterized by extensive fibrosis, multiple abscesses, and formation of sinus tracts that drain suppurative exudates. On the basis of the anatomical sites involved; it can be subclassified into the cervicofacial form, which is the most common form, pulmonary form and abdominal form. Kidneys are rarely affected. Clinically, radiologically, and at operation it is difficult to differentiate the renal actinomycosis from renal tuberculosis and renal carcinoma. The prognosis is excellent after nephrectomy followed by appropriate antibiotic therapy. We presented a case of renal actinomycosis with a brief review of the literatures.
Male
;
Humans
6.Percutaneous Pancreatic Stent Placement for Postoperative Pancreaticojejunostomy Stenosis: A Case Report.
Seung Koo YANG ; Chang Jin YOON
Korean Journal of Radiology 2016;17(5):797-800
Stenosis of the pancreatico-enteric anastomosis is one of the major complications of pancreaticoduodenectomy (PD). Endoscopic stent placement, has limited success rate as a nonsurgical treatment due to altered gastrointestinal anatomy. Percutaneous treatment is rarely attempted due to the technical difficulty in accessing the pancreatic duct. We reported a case of pancreaticojejunostomy stenosis after PD, in which a pancreatic stent was successfully placed using a rendezvous technique with a dual percutaneous approach.
Constriction, Pathologic*
;
Pancreatic Ducts
;
Pancreaticoduodenectomy
;
Pancreaticojejunostomy*
;
Stents*
7.Clinical Observation of the Vertical and the Marginal Fracture of the Patella
In KIM ; Jung Man KIM ; Seung Koo LEE ; Yang KIM ; Kyung Chul SHIN
The Journal of the Korean Orthopaedic Association 1988;23(4):977-982
Lately the incidences of the patella fracture have been increasing due to frequent traffic and industrial accident, popularity of sports activity and falling. Sixty-nine cases of patella fractures, which were treated at Department of Orthopedic Surgery, Hallym College in the years of 1980 to 1985, were reviewed and the authors obtained the following results : 1. Frequently involved were third to fifth decades. 2. Traffic accident was the most common cause of the fracture. 3. Out of 69 cases, 42 were treated by open reduction and internal fixation. Among them we used circumferential wiring for 22 cases, modified tension band wiring for 13 cases and tension band wiring for 7 cases respectively. The remaining 5 cases were treated by patellectomy. 4. The most favorable recovery from the fracture was obtsined from modified-tension-band-wiring group.
Accidental Falls
;
Accidents, Occupational
;
Accidents, Traffic
;
Incidence
;
Orthopedics
;
Patella
;
Sports
8.Surgical Treatment in Rheumatoid Wrist
In KIM ; Jung Man KIM ; Seung Koo LEE ; Yang KIM ; Hwa Ju YOON
The Journal of the Korean Orthopaedic Association 1989;24(1):127-138
The authors have analysed 39 rheumatoid wrists in 25 rheumatoid patients, who underwent vsrious surgeries including arthroscopic and open synovectomy, partial and total arthrodesis and total wrist arthroplasty at the department of orthopaedic surgery, St. Mary's Hospital from November 1985 to April 1988, and the effect of eaeh surgery on the wrist function and proper time of operation are discussed. The results were as follows; 1. The patients who were classified as a classical rheumatoid arthritis according to the ARA criteria were four males and twenty-one females, with a mean age of 43 yesrs, and the functional capacity of the patients before operation was graded in III for twenty-threeand in IV for two patients. 2. Out of 25 patients (39 wrists), 14 patients are in bilateral and II patients in unilateral involvement. The synovectomy in 13 wrists, arthrodesis in 24 wrists and total joint replacement in 2 wrists were performed and followed them for average 17 months after operation. 3. The synovectomy were done for 13 wrists in grade II and III according to the classification of rheumstoid arthritis by radiology(3). There were two cases of recurrence in the cases of synovectomy, but not in replacement and arthrodesis. 4. The arthrodesis of wrist was performed for 24 wrists-bilateral arthrodesis in 3 patient (6 wrists) and unilateral fusion in 18 patients. For 4 cases out of 24 cases of wrist arthrodesis, the second and third carpo-metacsrpal joints were fused simultaneously. 5. Protek total wrist arthroplasty was done in 2 cases snd followed them for more than9 months with relatively good clinical results. Finally, it is our beliefs for rheumatoid wrists that surgery is often indicated to control the various wrist problems, early synovectomy is strongly indicated, and partial wrist fusion has proven to be effective in patients with moderate destruction, deformity and pain, but the total wrist arthrodesis and arthroplasty is still in controversy. The proper surgery for rheumatoid wrist should be determined by the clinical severity of disease and radiological changes of wrist.
Arthritis
;
Arthritis, Rheumatoid
;
Arthrodesis
;
Arthroplasty
;
Classification
;
Congenital Abnormalities
;
Female
;
Humans
;
Joints
;
Male
;
Recurrence
;
Wrist
9.A Rotation
Jung Man KIM ; Seung Koo LEE ; Yang KIM ; Jae Hee SHIN
The Journal of the Korean Orthopaedic Association 1989;24(5):1491-1496
Rotation-plasty provides useful knee function and permits use of what is essentially an end-weight-bearing below-the knee prosthesis. This principle of rotating the foot was first used by Borggreve in 1930(3), in a patient with a short femur secondary to infection. Since then, this procedure has been used in congenital short femurs(4,6,7,), malignant bone tumors of the distal femur(1,5)and compound fracture with wide bone defect around the knee(2) We have performed this procedure in a case of focal femoral deficiency with 14cm shorter than the opposite femur due to long standing persistant chronic osteomyelitis in the mid-shaft femur of a nine-year old Korean boy and gave the good result with a conventional but slightly modified below- the-knee brace. The inverted foot was good to control the brace as a below-knee stump and heel functioned as a patella to support the body weight.
Body Weight
;
Braces
;
Femur
;
Foot
;
Fractures, Open
;
Heel
;
Humans
;
Knee
;
Knee Prosthesis
;
Male
;
Osteomyelitis
;
Patella
10.The Effect of Bromocriptine Treatment for Invasive Prolactinoma.
Moon Sool YANG ; Sun Ho KIM ; Seung Gil LIM ; Seung Koo LEE
Journal of Korean Neurosurgical Society 2005;37(4):275-281
OBJECTIVE: The prolactinoma is the most common pituitary tumor and sometimes shows severe invasiveness to the adjacent cavernous sinus, especially in the male patient. The dopamine agonist can be used as an alternative treatment modality to surgery. But, the transsphenoidal or transcranial approach for tumor removal has been more preferred treatment option of neurosurgeons in invasive prolactinoma. Especially rapid decompression of mass effect and resolution of the neurologic deficit is demanded. The prospective study is done in order to identify the therapeutic efficacy of bromocriptine as an initial treatment option for the invasive prolactionomas. METHODS: Twenty patients with invasive prolactinoma were studied. Preoperative neurological and endocrinological evaluations were done, and size and invasiveness of the tumor was estimated on MRI. Bromocriptine was administrated by increasing dose planning reaching maximum dose at 1month of treatment, with close neurological and endocrinological monitoring. At 3months after treatment, MRI was taken and decision was made whether to continue bromocriptine or to have surgical intervention. RESULTS: Thirteen patients showed excellent result with only bromocriptine treatment. These patients showed not only marked reduction of tumor volume and prolactin level, but also, improving clinical symptoms and other hormonal deficits. 13patients who had visual field defect and decreased visual acuity had all improved visual symptoms. But, the remaining 4patients required surgical treatment due to insufficient reduction of tumor size inspite of normalized prolactin level within 3months. Remaining 2patients had 20~30% of tumor size reduction, but prolactin level was not normalized. One patient required radiation therapy. CONCLUSION: Bromociptine can be used as initial treatment for the invasive prolactinomas with careful monitoring of the neurological and endocrinological status. It should be carefully followed up for tumor size reduction within 3 months after initiation of treatment.
Bromocriptine*
;
Cavernous Sinus
;
Decompression
;
Dopamine Agonists
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Neurologic Manifestations
;
Pituitary Neoplasms
;
Prolactin
;
Prolactinoma*
;
Prospective Studies
;
Tumor Burden
;
Visual Acuity
;
Visual Fields