1.Pantalar Arthrodesis
Sung Keun SOHN ; Seung Rim PARK ; Chang Il PARK
The Journal of the Korean Orthopaedic Association 1979;14(3):495-499
There are many procedures for stabilizing the foot but all frail feet, all complete drop feet, and all calcaneocavus deformities due to paralysis are best treated by pantalar fusion. Hunt and Thompson advised one stage pantalar arthrodesis by astragalectomy and replacement of the denuded bone in paraiytic feet resulting from poliomyelitis. At the Presbyterian Medical Center, Jeonju, Korea, 12 one stage pantalar arthrodesis were performed between 1973 and 1978 and following observations were made. 1. Seven of the patient had pantalar fusions because of poliomyelitis. 2. Five feet were equinovarus and 4 had frail feet with varying amounts of varus or valgus of the forepart of the foot and of the heel. 3. Nine patients were considered to have a good result, two had a fair and one was failure 4. Length of immobilization was from 13 weeks to 37 weeks and the average length of immobilization was 17 weeks. 5. In one stage pantalar arthrodesis, there was no complication except one non-union and the period of hospitalization was decreased.
Arthrodesis
;
Clubfoot
;
Congenital Abnormalities
;
Foot
;
Heel
;
Hospitalization
;
Humans
;
Immobilization
;
Jeollabuk-do
;
Korea
;
Paralysis
;
Poliomyelitis
;
Protestantism
2.A Case of Polymorphic Pemphigoid.
Seung Keun PARK ; Jai Il SUH ; Chull Wan IHM
Korean Journal of Dermatology 1983;21(4):467-471
Polymorphic pemphigoid is a polymorphic variant of bullous pemphigoid. Tbe authors had observed a case of polymorphic pemphigoid in a 54-year-ald woman, in whom generalized chronic blistering lesions and aevere pruritus were the main symptoms. The diagnosis of polymorphic pemphigoid was based on clinical, histopa.thological, immunopathological and therapeutic features.
Blister
;
Diagnosis
;
Female
;
Humans
;
Pemphigoid, Bullous*
;
Pruritus
3.Changes of Bone Mineral Density and IL-6 Levels after Bilateral Ovariectomies in Rats.
Seung Yeup HAN ; Sung Han KIM ; Keun Yong PARK
Korean Journal of Medicine 1997;53(3):346-351
OBJECTIVE: Estrogen is a major regulator/modulator of bone metabolism, and bone loss in estrogen deficiency is associated with increased bone turnover, But the mechanism for estrogen action on bone metabolism is still unknown. Recent studies have suggested that the increase in bone loss induced by estrogen deficiency is mediated by increased paracrine production of bone resorbing cytokines. Among cytokines, 1nterleukin-6(IL-6) is released from osteoblasts in estrogen deficiency and increases bone resorption by stimulation of osteoclastic activities and recruitment. Thus we performed this study to evaluate the effect of ovariectomies on bone mineral density and IL-6 in cultured monocytes of peripheral blood and bone marrow. METHODS: The experimental animals were 13 female Sprague-Dawley rats that were 8 weeks of age and weighed an average of 188.5 gram at the beginning of the study. Bilateral ovariectomies were performed in all rats from a ventral approach. Bone mineral density(BMD) of the total body, spine and level of IL-6 of cultured monocytes of peripheral blood and bone marrow were measured before and 8 weeks after ovariectomy. RESULTS: 1) BMD of total body and spine were lower after ovariectomy(0.257+/-0.069g/cm2, 0,208+/-0.005g/cm2) than before ovariectomy (0.276+/-0.005g/cm2, 0.229+/-0.011g/cm2), respectively (P<0.01). 2) Although IL-6 level of cultured monocytes in peripheral blood tended to be higher after ovariectomy than before ovariectomy, this difference was not statistically significant (P>0.05). 3) IL-6 level of cultured monocytes in bone marrow was higher after ovariectomy(82.78+/-4.99pg/ml) than before ovariectomy(48.85+/-2.42pg/ml)(P<0.05). CONCLUSION: It is possible that increased production of IL-6 in estrogen deficiency induced by ovariectomy occurs in the local environment of bone or bone marrow rather than in the pheripheral blood and stimulates bone resorption.
Animals
;
Bone Density*
;
Bone Marrow
;
Bone Resorption
;
Cytokines
;
Estrogens
;
Female
;
Humans
;
Interleukin-6*
;
Metabolism
;
Monocytes
;
Osteoblasts
;
Osteoclasts
;
Ovariectomy*
;
Rats*
;
Rats, Sprague-Dawley
;
Spine
4.Effect of growth factors and differentiation inducer DMSO on the anaplastic thyroid carcinoma cell line, SNU-80.
Seung Keun OH ; Dong Young NOH ; Jae Gahb PARK
Journal of the Korean Cancer Association 1991;23(2):237-246
No abstract available.
Cell Line*
;
Dimethyl Sulfoxide*
;
Intercellular Signaling Peptides and Proteins*
;
Thyroid Gland*
;
Thyroid Neoplasms*
5.Clinical Use of Cast
Sung Keun SOHN ; Seung Rim PARK ; Won Mo YANG
The Journal of the Korean Orthopaedic Association 1980;15(1):78-83
30 cases of distal femur fracture were treated with cast-brace for 2 years and 6 months from Feb., 1977 till July, 1979 at the department of Orthopaedic Surgery, Presbyterian Medical Center, in Jeon Ju. The results were obtained as follows: 1. In 9 cases, cast-brace were applied initially and other 21 cases were treated with cast-brace secondarily after operation. 2. 20 cases were male and 10 cases were female. 3. 12 cases were on mid 1/3 fracture and 18 cases were distal 1/3 fracture involving 2 condylar fractures. 4. The average duration of fracture healing was 14.7 weeks in the cases with cast-brace which is compared with 20.7 weeks of hip-spica cast control group. 5. A.G.F. of knee joint was 80–115 degree at removal of cast-brace, otherwise merely 50–65 degree at dlscarding of hip-spica cast. 6. There were no complication such as nonunion or delayed union in the cases with cast-brace.
Braces
;
Female
;
Femur
;
Fracture Healing
;
Humans
;
Jeollabuk-do
;
Knee Joint
;
Male
;
Protestantism
6.Harrington Instrumentation
Sung Keun SOHN ; Seung Rim PARK ; Sun NAMGOONG
The Journal of the Korean Orthopaedic Association 1980;15(1):30-36
Harrington Instrumentation is very effective method for treating the unstable thoraco-lumbar spine fracture and fracture-dislocations. Authors performed Harrington Instrumentations in 8 cases of unstable thoraco-lumbar spine fracture and fracture-dlslocations. The results obtained were as follows; 1. Spinal fracture and fracture-dislocations are most common in thoraco-lumbar junction. 2. Laminectomy increases the instability of the spine. 3. Pain was more common in the patient who has severe deformity of the spine. 4. Neurological recovery; a) In case of complete paralysis... returns of useless motor power in 2 of 6 cases. b) In case of incomplete paralysis... complete returns in all 2 patients. 5. Harrington Instrumentation is very effective for restoring the spine stability in unstable fracture and fracture-dislocations. 6. Early mobilization was possible and hospitalization period was shortened by Harrington Instrumentation.
Congenital Abnormalities
;
Early Ambulation
;
Hospitalization
;
Humans
;
Laminectomy
;
Methods
;
Paralysis
;
Spinal Fractures
;
Spine
7.A Clinical Study of the Surgical Treatment of the Cervical Spine Injuries
Sung Keun SOHN ; Seung Rim PARK ; Kyu Hyoung KIM
The Journal of the Korean Orthopaedic Association 1980;15(2):278-287
Cervical spine injuries are increasing recently due to increasing traffic accidents. Many patients have been treated with cervical laminectomy but stabilization of the cervical spine has been neglected as a part of the treatment. 30 patients with cervical spine injuries who were admitted to our hospital from January 1, 1973 to December 31, 1978 were evaluated. The following observations were made: 1. The ratio between male and female was 2:1 and the majority(43%) were found in the 4th decades. 2. The common causes of cervical spine injuries were traffic accident(40%) and falls(33.3%). The most common site of the lesion was the 5th and 6th cervical spine level (33.3%). 3. Among 30 cases, 10 cases(33.3%) had complete paralysis, 12 cases(40%) incomplete paralysis, 6 cases (20%) had nerve root injury and no neurological change is 2 cases. 4. The mechanisms of cervical injuries were classified morphologically and flexion-rotation injuries (55.5%) were the most common. 5. We evaluated the results of treatment neurological & radiographically. In complete paralysis, there was no neurological improvement and cervical kyphosis increased after laminectomy. In incomplete paralysis and nerve root injury, anterior fusion showed slight neurological recovery but mild cevical kyphosis and displacement of the graft were observed. In posterior fusion or cast immobilization, we had a satisfactory result with a high fusion rate and normal cervical curvature. 6. lt is impossible to compare anterior interbody fusion with posterior fusion for neurological recovery. For early mobilization and rehabilitation, we emphasize early stabilization by anterior or posterior fusion according to the mechanism of injury.
Accidents, Traffic
;
Clinical Study
;
Early Ambulation
;
Female
;
Humans
;
Immobilization
;
Kyphosis
;
Laminectomy
;
Male
;
Paralysis
;
Rehabilitation
;
Spine
;
Transplants
8.Clinical Study on Early Diagnosis of Skeletal Disorders by Bone Scan with Tc-99m-MDP (Medronate)
Byeong Mun PARK ; Jun Seop JAHNG ; Seung Keun SONG
The Journal of the Korean Orthopaedic Association 1983;18(2):196-208
Early detection of skeletal disorders was very important role in establishing therapeutic modality and prevention of complications. Since Tc-99m-phosphates derivatives used in bone scan agent, remarkable improvement was noted in effectiveness, cost, radiation hazard to patient and image quality than previously used agents such as strontium or fluoride. Bone scan with Tc-99m-MDP was done in 155 cases for early diagnosis of skeletal disorders at Severance Hospital, College of Medicine, Yonsei University from August, 1980 to May, 1982 were analyzed both clinically and radiologically, and the following results were obtained. l. Among 19 cases of avascular necrosis, positive cases were 17 (89.5%) in bone scan and 6(31.6%) in X-ray. Positive pattern could be classified into 3 types and the radionuclide uptake in the femoral head was decreased in 3 cases which was negative in X-ray and duration of their symptoms was within 4 months. 2. Fifteen among 17 hip fractures or dislocations were positive in bone scan. In 12 (80.0%) among 15 cases, complications were revealed and positive cases in X-ray were 7(58.3%), which were all positive in bone scan. 3. In 20 bone scans for early diagnosis of acute osteomyelitis, positive in bone scan were 17 and 14 (82.4%) of 17 cases were finally diagnosed as acute osteomyelitis. Among 15 cases diagnosed as acute osteomyelitis, positive in X-ray were 8(53.3%) and sensitivity of acute osteomyelitis in bone scan was 93.3%. 4. In 25 cases of the suspected infection of the joint, 15 were positive in bone scan and among them, cases diagnosed as pyogenic arthritis were 12 (80.0%) and positive in X-ray were 2 (16.7%). Only one of 10 cases of transient synovitis of the hip joint was positive in bone scan. 5. In rheumatoid arthritis, 13 of 15 cases were positive in bone scan and 10 among them were revealed the diffuse uptake of the radionuclide in the joint. In degenerative arthritis, 7 of 8 cases were positive in bone scan and they were revealed the focal uptake of the radionuclide in the same site where the bone was changed in x-ray. 6. Among 28 cases showed spine fracture in X-ray after trauma, 15 (53.6%) were positive in bone scan. In spine fracture, it was difficult to differentiate fresh fracture from old fracture with bone scan. The positive duration of bone scen in fracture of weight bearing bone was longer than in spine fracture. Rib fracture which was not found in X-ray could be diagnosed with bone scan.
Arthritis
;
Arthritis, Rheumatoid
;
Clinical Study
;
Cost-Benefit Analysis
;
Diagnosis
;
Dislocations
;
Early Diagnosis
;
Fluorides
;
Head
;
Hip Fractures
;
Hip Joint
;
Humans
;
Joints
;
Necrosis
;
Osteoarthritis
;
Osteomyelitis
;
Rib Fractures
;
Spine
;
Strontium
;
Synovitis
;
Weight-Bearing
9.A Clinical Study on Ligamentous Injuries of the Knee
Sung Keun SOHN ; Seung Rim PARK ; Han Sol YANG
The Journal of the Korean Orthopaedic Association 1984;19(2):397-405
The function of the knee joint is determined by the anatomical integrity of ligamentous structures, however the ligaments and soft tissues which support by the knee joint are too weak to tolerate forceful stresses. The knee joint is one of the most susceptible joints to ligamentous injury. Recently, the incidence of ligamentous injuries of the knee increased because of rise in traffic accidents and participation in sports. For good results, it is very important to make an early diagnosis and to give prompt management. The authors reviewed 67 cases of ligamentous injuries in patients who were admitted and managed at the Department of Orthopaedic Surgery of Presbyterian Medical Center from March of 1976 to December of 1982. The results of the clinical study are as follows: 1. The prevalent age group is the 3rd through 5th decades, and more frequent in males (8. 6 times). 2. The traffic accident is the most common cause of injury (80. 6%) and many ligamentous injuries were associated with fracture (53. 2%). 3. The most common ruptured individual ligament was the medial collateral ligament. The isolated ligamentous rupture of anterior and posterior cruciate ligament was 3 cases each, but most of the cruciate ligaments were combined with other ligament injury. 4. The rupture sites of the individual ligaments were found to be the following: (a) The medial collateral ligament was ruptured most frequently in the mid-substance (45. 2%), with the deep layer ruptured at the femoral attachment and the superficial layer in the mid-substance; (b) The lateral collateral ligament torn at the fibular attachment (62. 5%); (c) The anterior cruciate ligament torn at the femoral and tibial (47. 6%, respectively); (d) The posterior cruciate ligament torn at the femoral attachment (40. 0%). 5. It is significant if the difference between the normal knee and the injured knee on the stress film is more than 10 or 10mm. 6. Excellent and good results were obtained in 95.2% by non-surgical management and in 93.0% by surgical management. 7. Early surgical repairs, made within 2 weeks after injury, gave much better results than late repairs.
Accidents, Traffic
;
Anterior Cruciate Ligament
;
Clinical Study
;
Collateral Ligaments
;
Early Diagnosis
;
Humans
;
Incidence
;
Joints
;
Knee Joint
;
Knee
;
Lateral Ligament, Ankle
;
Ligaments
;
Male
;
Posterior Cruciate Ligament
;
Protestantism
;
Rupture
;
Sports
10.A Clinical Study of Buerger's Disease
Sung Keun SOHN ; Seung Rim PARK ; In Sang KIM
The Journal of the Korean Orthopaedic Association 1984;19(2):325-331
Beurgers disease is a specific, recurrent, segmental, inflammatory, obliterative vascular disease involving principally the medium sized arteries and veins of the extremities. The disease was originally described by Leo Beurger in 1908. The results in treatment were not satisfactory in spite of many interaction and experiencies in treatment. So the present study is clinical analysis of 136 cases of Beurgers disease, who were treated at the Department of Orthopaedic Surgery and General Surgery, Presbyterian Medical Center, for the past 12 years, from 1971 to 1982. The results obtained are as follows: Sex distribution was predominent in male(97.1%) and peak incidence in the fourth decade. One hundred twenty eight cases had smoked over 10 years and sixty percent had more than one operation previously because of the same disease. The most common symptom was pain in the extrimities, necrosis, skin color change and coldness were in that order of frequency. The lower extremities were more commonly involved. The most common site of obstruction at the arteriogram was the popliteal artery. Among the surgery cases, 20 of the sympathetomized patients had followed-up, and the long term result showed improvement in 17 cases and all the results of the vascular surgery were poor.
Arteries
;
Clinical Study
;
Extremities
;
Humans
;
Incidence
;
Lower Extremity
;
Necrosis
;
Popliteal Artery
;
Protestantism
;
Sex Distribution
;
Skin Pigmentation
;
Smoke
;
Thromboangiitis Obliterans
;
Vascular Diseases
;
Veins