No abstract available.
Humans ; Shock*

The antihypertensive effect of Minizide(0.5mg prazosin hydrochloride and 0.25mg polythiazide per tablet)was evaluated in 30 patients with essential hypertension with a dosage of one tablet a day for four weeks. The results were as follows : 1) Of 30 patients treated with Minizide, 21 patients(70.0%) achieved normalization of blood pressure and 5 patients(16.7%) had good response. 2) Mean drop in systolic and diastolic pressure were 29.0mmHg and 15.9mmHg respectively in supine position(P<0.005). 3) Mean drop in systolic and diastolic pressure were 28.5mmHg and 16.2mmhg respectively in sitting position(P<0.005). 4) In 14 patients(46.7%) among 30 patients treated with Minizide adverse reactions developed. The most frequent one was postural dizziness(23.3%). 5) Most adverse reactions were transient and tolerable. However, in three patients(two patients with postural dizziness and one patient with dry mouth) the medication was stopped due to adverse reactions.
Blood Pressure ; Dizziness ; Humans ; Hypertension ; Polythiazide ; Prazosin

The detailed descriptions about clinical features and management of the different types of peripheral neuropathy are beyond the scope of this article. It may be appropriate here to outline general aspects of clinical features and classification of peripheral neuropathies. The clinical history and the abnormalities revealed by physical examination may either suggest the diagnosis or narrow down the diagnostic possibilities, facilitating subsequent investigation. Nerve conduction studies can provide crucial information and are best performed at initial examination. In general, the first broad determination should be made whether the patient has symmetrical polyneuropathy or focal, or multifocal neuropathies. The range of diagnostic possibilities differs between symmetrical polymeuropathy and mutifocal neuropathy. For those patients with symmetrical polyneuropathy, the clinical pattern (that is, whether it is motor, sensory, or mixed, or whether it has proximal or distal distribution) can provide useful information, as well as the rapidity of onset and previous clinical course in established cases. Managements of peripheral neuropathy and planning of its treatment mostly depend on the confirmative diagnosis of peripheral neuropathy. Thus, the best knowledge and understanding of basic principles of peripheral neuropathies are required for facilitating the diagnosis of peripheral neuropathies.
Classification ; Diagnosis* ; Humans ; Neural Conduction ; Peripheral Nervous System Diseases* ; Physical Examination ; Polyneuropathies

In this book review, Contents have been misspelled.

No abstract available.
Diagnosis* ; Diuretics ; Edema*

PURPOSE: To evaluate imaging characteristics of metastatic renal tumors in CT and US. MATERIALS AND METHODS: Renal metastases were diagnosed in 25 patients by surgery (n=2), US-guided biopsy (n=15), or follow-up CT (n=8). The primary tumors metastasized to kidney were lung cancer (n=11), adenold cystic carcinoma (n=3), stomach cancer (n=2), and choriocarcinoma (n=2). Twelve cases invloved one kidney and 13 invloved both kidneys. CT was performed in all 25 patients while US was done in 14. We analysed CT findings in respect to number, size, shape, exophytic degree, margin, and degree and homogeneity of the contrast enhancement of the lesion; US findings in regand to echogenicity and homogeneity of the lesion. RESULTS: The average number of the lesions per patient seen on CT was three;average diameter of the lesion was 3.6cm; and 75% (57/76) of all tumors had exophytic degree of 0%. The characteristic CT findings of metastatic renal tumors were round shape (52/76), ill-defined margin (54/76), and poor (76/76) and inhomogeneous (45/76) contrast enhancement. The echogenicity of the tumors were homogeneous (11/18) and isoechoic (10/18) on US. CONCLUSION: Metastatic renal tumors had a tendency of multiple, small, ill-marginated, and less-exophytic nature on CT, and homogeneous, isoechoic appearance on US. The familiarity with the constellation of CT and US findings of renal metastasis described may be helpful in making a correct diagnosis.
Biopsy ; Choriocarcinoma ; Diagnosis ; Female ; Follow-Up Studies ; Humans ; Kidney ; Lung Neoplasms ; Neoplasm Metastasis* ; Pregnancy ; Recognition (Psychology) ; Stomach Neoplasms

The effects of Prazosin administered alone or in combination were studied in 30 hypertensive patients at the Busan national University Hospital, Korea, between August 1974 and march 1975. The Patients were studied for up to 6 months; their ages ranged from 17 years to 68 years with mean age 51.4 years; 15 patients were male and 15 female. Satisfactory control of blood pressure was achieved in all patients. The group controlled by prazosin alone had the lowest mean original blood pressures, the group requiring prazosin plus polythiazide occupied an intermediate position, and the group requiring prazosin plus polythiazide plus beta blockade had the highest mean original blood pressures. 6 patients responded satisfactorily to prazosin, alone. In this group the supine systolic blood pressures before and after treatment were 185+/-16 and 150+/-12mmHg respectively; the supine diastolic pressures 106+/-5 and 90+/-3mmHg respectively. The standing systolic blood pressures before and after treatment were 173+/-13 and 134+/-4mmHg respectively; the standing diastolic pressures 102+/-5mmHg and 81+/-6mmHg respectively. 17 patients responded satisfactorily to the combination of prazosin and polythiazide. In this group the supine systolic blood pressures before and after treatment were 197+/-26 and 148+/-16mmHg respectively; the supine diastolic pressures before and after treatment were 121+/-13 and 92+/-6mmHg respectively. The standing systolic blood pressures before and after treament were 188+/-27 and 148+/-16mmHg respectively; the standing diastolic pressures before and after treatment were 110+/-14 and 85+/-5mmHg respectively. The remaining 7 patients responded satisfactorily to the combination of prazosin, polythiazide and a beta blocking agent (tolamolol). In this group the supine systolic blood pressures before and after treatment were 230+/-25 and 181+/-6mmHg respectively; the supine diastolic pressures before and after treatment were 138+/-15 and 93+/-6mmHg respectively. The standing systolic blood pressures before and after treatment were 224+/-24 and 151+/-9mmHg respectively; the standing diastolic pressures before and after treatment were 136+/-12 and 75+/-4mmHg respectively. 5 patients complained of headache, palpitations and general malaise; oedema was observed in 5 patients; 5 patients complained of drowsiness and 5 patients, fatiguability. In each case the side effects were of short duration not lasting beyond 3 days.
Blood Pressure ; Busan ; Female ; Headache ; Humans ; Korea* ; Male ; Polythiazide ; Prazosin* ; Sleep Stages

The effects of Prazosin administered alone or in combination were studied in 30 hypertensive patients at the Busan national University Hospital, Korea, between August 1974 and march 1975. The Patients were studied for up to 6 months; their ages ranged from 17 years to 68 years with mean age 51.4 years; 15 patients were male and 15 female. Satisfactory control of blood pressure was achieved in all patients. The group controlled by prazosin alone had the lowest mean original blood pressures, the group requiring prazosin plus polythiazide occupied an intermediate position, and the group requiring prazosin plus polythiazide plus beta blockade had the highest mean original blood pressures. 6 patients responded satisfactorily to prazosin, alone. In this group the supine systolic blood pressures before and after treatment were 185+/-16 and 150+/-12mmHg respectively; the supine diastolic pressures 106+/-5 and 90+/-3mmHg respectively. The standing systolic blood pressures before and after treatment were 173+/-13 and 134+/-4mmHg respectively; the standing diastolic pressures 102+/-5mmHg and 81+/-6mmHg respectively. 17 patients responded satisfactorily to the combination of prazosin and polythiazide. In this group the supine systolic blood pressures before and after treatment were 197+/-26 and 148+/-16mmHg respectively; the supine diastolic pressures before and after treatment were 121+/-13 and 92+/-6mmHg respectively. The standing systolic blood pressures before and after treament were 188+/-27 and 148+/-16mmHg respectively; the standing diastolic pressures before and after treatment were 110+/-14 and 85+/-5mmHg respectively. The remaining 7 patients responded satisfactorily to the combination of prazosin, polythiazide and a beta blocking agent (tolamolol). In this group the supine systolic blood pressures before and after treatment were 230+/-25 and 181+/-6mmHg respectively; the supine diastolic pressures before and after treatment were 138+/-15 and 93+/-6mmHg respectively. The standing systolic blood pressures before and after treatment were 224+/-24 and 151+/-9mmHg respectively; the standing diastolic pressures before and after treatment were 136+/-12 and 75+/-4mmHg respectively. 5 patients complained of headache, palpitations and general malaise; oedema was observed in 5 patients; 5 patients complained of drowsiness and 5 patients, fatiguability. In each case the side effects were of short duration not lasting beyond 3 days.
Blood Pressure ; Busan ; Female ; Headache ; Humans ; Korea* ; Male ; Polythiazide ; Prazosin* ; Sleep Stages

No abstract available.
Diagnostic Errors*

The author analyzed the clinical study of 214 patients with congestive heart failure who were confirmed by the clinical symptoms and the laboratory findings among the admitted patients in Busan university Hospital between 1965 and 1972. The results were summarized as follows: There were males 127 and females 87 of 214 cases and the incidence was the highest in the 6th decade. The etiologic diagnosis was listed in table 2, that showed the rheumatic heart disease 34.6%, arteriosclerotic heart disease 23.8% and hypertensive heart disease 22.4% of total patients. The important symptoms such as dyspnea, palpitatia, fatigability, cough, chest discomfort and orthopnea were noticed and the physical findings such as heart murmur, hepatomegaly, edema, enlarged cervical veins, pulmonary congestion, arrhythmia and thrill were revealed on the admission. The venous pressure, measured in 85 patients, was above 150mm H20 in 71 cases. The serum chemical findings were listed in table 6 and abnormal retention of BSP was the most sensitive in congestive heart failure. The level of NPN, VUN and ceatinine was increased in one quarter of total cases. The clinical symptoms and laboratory findings were more severe in the right heart failure or the right and left heart failure than in the left heart failure. ESR was increased in 66.7% of cases and albuminuria was revealed in 47.1%. The E.C.G. findings at admission revealed prolonged Q-Tc(41%), inverted T wave(44.3%), LVH(43.2%), depressed ST segment (35.2%), flat T wave (30.7%) and atrial fibrillation(27.8%). The Chest X-ray findings showed cardiomegaly(42.2%), Pulmonary congestion and cardiomegaly(20.3%), pulmonary congestion (11.2%) and pericarditis (4.2%).
Female ; Male ; Humans ; Incidence