1.Intramuscular Baker's Cyst in Plantaris: A Case Report.
Chang Hun LEE ; June Mo NOH ; Tai Seung KIM
The Journal of the Korean Bone and Joint Tumor Society 2012;18(1):28-31
Baker's cyst is found as most frequent cystic mass around the knee occurring between medial head of gastrocnemius muscle and semimembranosus muscle. The proximal or posterolateral extension of the cyst had been rarely reported and the cyst into the surrounding muscular tissue extremely rare. Intramuscular Baker's cyst that we report was found between lateral head of gastrocnemius muscle and popliteus tendon, and then extended into the plantaris muscle. With review of the literature, we here report a very rare case of plantaris muscular extension of Baker's cyst.
Head
;
Knee
;
Muscle, Skeletal
;
Muscles
;
Popliteal Cyst
;
Tendons
2.Retrospective analysis of treatment outcomes after postoperative chemoradiotherapy in advanced gastric cancer.
Sup KIM ; Jun Sang KIM ; Hyun Yong JEONG ; Seung Moo NOH ; Ki Whan KIM ; Moon June CHO
Radiation Oncology Journal 2011;29(4):252-259
PURPOSE: To evaluate retrospectively the survival outcome, patterns of failure, and complications in patients treated with postoperative chemoradiotherapy (CRT) in advanced gastric cancer. MATERIALS AND METHODS: Between January 2000 and December 2006, 80 patients with advanced gastric cancer who received postoperative concurrent CRT were included. Pathological staging was IB-II in 9%, IIIA in 38%, IIIB in 33%, and IV in 21%. Radiotherapy consisted of 45 Gy of radiation. Concurrent chemotherapy consisted of a continuous intravenous infusion of 5-fluorouracil and leucovorin on the first 4 days and last 3 days of radiotherapy. RESULTS: The median follow-up period was 48 months (range, 3 to 83 months). The 5-year overall survival, disease-free survival, and locoregional recurrence-free survivals were 62%, 59%, and 80%, respectively. In the multivariate analysis, significant factors for disease-free survival were T stage (hazard ratio [HR], 0.278; p = 0.038), lymph node dissection extent (HR, 0.201; p = 0.002), and maintenance oral chemotherapy (HR, 2.964; p = 0.004). Locoregional recurrence and distant metastasis occurred in 5 (6%) and 18 (23%) patients, respectively. Mixed failure occurred in 10 (16%) patients. Grade 3 leukopenia and thrombocytopenia were observed in 4 (5%) and one (1%) patient, respectively. Grade 3 nausea and vomiting developed in 8 (10%) patients. Intestinal obstruction developed in one (1%). CONCLUSION: The survival outcome of the postoperative CRT in advanced gastric cancer was similar to those reported previously. Our postoperative CRT regimen seems to be a safe and effective method, reducing locoregional failure without severe treatment toxicity in advanced gastric cancer patients.
Chemoradiotherapy
;
Combined Modality Therapy
;
Disease-Free Survival
;
Fluorouracil
;
Follow-Up Studies
;
Humans
;
Infusions, Intravenous
;
Intestinal Obstruction
;
Leucovorin
;
Leukopenia
;
Lymph Node Excision
;
Multivariate Analysis
;
Nausea
;
Neoplasm Metastasis
;
Radiotherapy, Adjuvant
;
Recurrence
;
Retrospective Studies
;
Stomach Neoplasms
;
Thrombocytopenia
;
Vomiting
3.Short-term Effect of Radical Hysterectomy with or without Adjuvant Radiation Therapy on Urodynamic Parameters in Patients with Uterine Cervical Cancer.
Jin Kyu OH ; Min Soo CHOO ; Joongyub LEE ; Noh Hyun PARK ; Seung June OH
International Neurourology Journal 2012;16(2):91-95
PURPOSE: Lower urinary tract dysfunction is the most common complication after radical pelvic surgery. The aims of this study were to assess the effect of radical hysterectomy (RH) on the storage function of the lower urinary tract and to evaluate the impact of radiation therapy (RT) on postoperative urodynamic parameters. METHODS: This was a retrospective review of preoperative and postoperative urodynamic variables, which were prospectively collected. All women from 2006 to 2008, who underwent RH for uterine cervical cancer with a stage of 1A to 2B with or without adjuvant RT were enrolled. All patients were divided into two groups: group 1, without RT, and group 2, with adjuvant RT. Urodynamic studies were performed before, 10 days after, and 6 months after RH. RESULTS: A total of 42 patients with a mean (+/-standard error) age of 51.9 (+/-12.3) years were analyzed. There were no significant differences in age, body mass index or clinical stage between the two groups. On the 10th postoperative day, all parameters were decreased except postvoid residual volume. In comparison with group 2 (n=14), group 1 (n=28) showed a significant increase in bladder compliance. At 6 months postoperatively, bladder compliance in group 1 had increased four times or more compared with that on postoperative 10 days. However, it had increased only 2.5 times in group 2 at the same time point (P<0.001). CONCLUSIONS: The results of our study suggest that adjuvant RT after RH might result in a deterioration of bladder compliance. It is highly suggested that practitioners pay attention to low bladder compliance, especially in patients who have adjuvant RT after RH.
Body Mass Index
;
Compliance
;
Female
;
Humans
;
Hysterectomy
;
Prospective Studies
;
Residual Volume
;
Retrospective Studies
;
Urinary Bladder
;
Urinary Tract
;
Urodynamics
;
Uterine Cervical Neoplasms
4.Ductal Adenocarcinoma Arising from Heterotopic Pancreas in the Stomach: A Case Report.
Young Seob AHN ; June Sik CHO ; Kyung Sook SHIN ; Seung Moo NOH ; Hyun Yong JEONG ; Kyu Sang SONG
Journal of the Korean Radiological Society 2001;45(1):51-53
Malignant transformation of heterotopic pancreas is extremely rare. We report a case of ductal adenocarcinoma arising from heterotopic pancreas in the stomach of a 64-year-old man. Preoperative CT scans showed the lesion as a submucosal mass along the greater curvature of the pyloric antrum and protruding into the pyloric canal. After gastric surgery, the resected tumor was histopathologically diagnosed as a ductal adenocarcinoma arising from heterotopic pancreas with cystic dilatation of aberrant pancreatic duct.
Adenocarcinoma*
;
Dilatation
;
Humans
;
Middle Aged
;
Pancreas*
;
Pancreatic Ducts
;
Pyloric Antrum
;
Stomach*
;
Tomography, X-Ray Computed
5.Mesenteric Paraganglioma with Cystic Degeneration: Case Report.
Dae Bong KIM ; June Sik CHO ; Kyung Sook SHIN ; Byung Seok SHIN ; Seung Moo NOH ; Dae Young KANG
Journal of the Korean Radiological Society 2003;49(3):207-210
Extra-adrenal abdominal paragangliomas are rare. Most arise from the organs of Zuckerkandl, involve large concentrations of paraganglionic tissue, and are located in the para-aortic space along the sympathetic chain. Published reports have, however, described normal paraganglionic tissue at the root of the mesentery which serves as the superior limit of the organs of Zuckerkandl, and mesenteric paraganglioma is very rare. We report a case of paraganglioma with cystic degeneration arising from the mesentery.
Mesentery
;
Para-Aortic Bodies
;
Paraganglioma*
6.A Nationwide Survey of mRNA COVID-19 Vaccinee’s Experiences on Adverse Events and Its Associated Factors
Dongwon YOON ; Ha-Lim JEON ; Yunha NOH ; Young June CHOE ; Seung-Ah CHOE ; Jaehun JUNG ; Ju-Young SHIN
Journal of Korean Medical Science 2023;38(22):e170-
Background:
Although coronavirus disease 2019 (COVID-19) vaccines have been distributed worldwide under emergency use authorization, the real-world safety profiles of mRNA vaccines still need to be clearly defined. We aimed to identify the overall incidence and factors associated with adverse events (AEs) following mRNA COVID-19 vaccination.
Methods:
We conducted web-based survey from December 2 to 10 in 2021 with a 2,849 nationwide sampled panel. Study participants were individuals who had elapsed at least twoweeks after completing two dosing schedules of COVID-19 vaccination aged between 18–49 years. We weighted the participants to represent the Korean population. The outcome was the overall incidence of AEs following mRNA COVID-19 vaccination and associated factors.We estimated the weighted odds ratios (ORs) using multivariable logistic regression models to identify the factors associated with AEs.
Results:
Of the 2,849 participants (median [interquartile range] age, 35 [27–42] years; 51.6% male), 90.8% (n = 2,582) for the first dose and 88.7% (n = 2,849) for the second dose reported AEs, and 3.3% and 4.3% reported severe AEs, respectively. Occurrence of AEs was more prevalent in mRNA-1273 (OR, 2.06; 95% confidence interval [CI], 1.59–2.67 vs. BNT162b2), female sex (1.88; 1.52–2.32), and those with dermatologic diseases (2.51; 1.32–4.77). History of serious allergic reactions (1.96; 1.06–3.64) and anticoagulant medication use (4.72; 1.92–11.6) were associated with severe AEs.
Conclusion
Approximately 90% of participants reported AEs following mRNA COVID-19 vaccination. Substantial factors, including vaccine type (mRNA-1273), female sex, and dermatologic diseases were associated with AEs. Our findings could aid policymakers in establishing vaccination strategies tailored to those potentially susceptible to AEs.
7.Barriers to COVID-19 vaccine surveillance: the issue of under-reporting adverse events
Yunha NOH ; Hwa Yeon KO ; Ju Hwan KIM ; Dongwon YOON ; Young June CHOE ; Seung-Ah CHOE ; Jaehun JUNG ; Ju-Young SHIN
Epidemiology and Health 2023;45(1):e2023054-
OBJECTIVES:
This study investigated the reporting rates of adverse events following immunization (AEFIs) to the spontaneous reporting system (SRS) and its predictors among individuals with AEFIs after coronavirus disease 2019 (COVID-19) vaccination.
METHODS:
A cross-sectional, web-based survey was conducted from December 2, 2021 to December 20, 2021, recruiting participants >14 days after completion of a primary COVID-19 vaccination series. Reporting rates were calculated by dividing the number of participants who reported AEFIs to the SRS by the total number of participants who experienced AEFIs. We estimated adjusted odds ratios (aORs) using multivariate logistic regression to determine factors associated with spontaneous AEFIs reporting.
RESULTS:
Among 2,993 participants, 90.9% and 88.7% experienced AEFIs after the first and second vaccine doses, respectively (reporting rates, 11.6 and 12.7%). Furthermore, 3.3% and 4.2% suffered moderate to severe AEFIs, respectively (reporting rates, 50.5 and 50.0%). Spontaneous reporting was more prevalent in female (aOR, 1.54; 95% confidence interval [CI], 1.31 to 1.81); those with moderate to severe AEFIs (aOR, 5.47; 95% CI, 4.45 to 6.73), comorbidities (aOR, 1.31; 95% CI, 1.09 to 1.57), a history of severe allergic reactions (aOR, 2.02; 95% CI, 1.47 to 2.77); and those who had received mRNA-1273 (aOR, 1.25; 95% CI, 1.05 to 1.49) or ChAdOx1 (aOR, 1.62; 95% CI, 1.15 to 2.30) vaccines versus BNT162b2. Reporting was less likely in older individuals (aOR, 0.98; 95% CI, 0.98 to 0.99 per 1-year age increment).
CONCLUSIONS
Spontaneous reporting of AEFIs after COVID-19 vaccination was associated with younger age, female sex, moderate to severe AEFIs, comorbidities, history of allergic reactions, and vaccine type. AEFIs under-reporting should be considered when delivering information to the community and in public health decision-making.
8.The Detection of Cancer in Augmented Breast by Positron Emission Tomography.
Dong Young NOH ; Han Sung KANG ; Ik Jin YUN ; Ji Soo KIM ; June Key CHUNG ; Dong Soo LEE ; Myung Chul LEE ; Yeo Kyu YOUN ; Seung Keun OH ; Kuk Jin CHOE
Journal of Korean Breast Cancer Society 1999;2(1):44-50
As breast cancer in patients who have undergone augmentation mammoplasty is usually detected late, prognosis is worse than it would otherwise be. Mammography has led to remarkable in the diagnosis of breast cancer, but didnot so in cancer arising from augmented breasts. FDG-PET, which uses fluorine-18-fluorodeoxy glucose (FDG), a glucose non-metabolized analogue , is able to detect breast cancer which shows more active rates of glucose metabolism. Cancer in a radioopaque dense breast, such as breast with silicone- or paraffin-augmentation and is not found by mammography, might be detected by FDG-PET. We tried to find out diagnostic efficienty of FDG-PET in detecting breast cancer with augmented breast. Between June 1995 and November 1997, eight patients had a history of breast augmentation with silicone or paraffin. Although most of them were examined at local clinic by physical exam, mammography or ultrasonography before visiting our hospital, definitive diagnosis could not be made. One patients wanted both breasts augmentsed with paraffin to be removed, and PET evaluated a total of nine lesions with pathological confirmation. As a result, the mammography detected the breast cancer in only one out of three malignancies, and ultrasonography made false positive result in one patient in augmented breast. In contrast, PET scan predicted all of malignancies and five out of six benign lesions precisely. Two of three breast cancers had axillary FDG uptake interpreted as consistent with metastatic involvement, and in one case with cancer of negative axillary lymph node involvement there was no FDG uptake in the axilla, which were correlated to pathologic finding. Although its high cost made the use of PET as a screening test for all augmented breast not feasible, it would, however, be the best diagnostic choice if other methods failed.
Axilla
;
Breast Neoplasms
;
Breast*
;
Diagnosis
;
Electrons*
;
Female
;
Glucose
;
Humans
;
Lymph Nodes
;
Mammaplasty
;
Mammography
;
Mass Screening
;
Metabolism
;
Paraffin
;
Positron-Emission Tomography*
;
Prognosis
;
Silicones
;
Ultrasonography
9.Roux Stasis Syndrome in Conventional Roux-en-Y Gastrojejunostomy and Uncut Roux-en-Y Gastrojejunostomy after Subtotal Gastrectomy.
Seung Moo NOH ; Jin Sun BAE ; Hyun Yong JEONG ; June Sik CHO ; Kyung Sook SHIN ; Kyu Sang SONG
Journal of the Korean Gastric Cancer Association 2001;1(1):38-43
PURPOSE: Roux stasis syndrome is the main complication of a Roux-en-Y gastrojejunostomy. The aim of this study was to compare the occurrence rate of Roux stasis syndrome with the passing of time in a conventional Roux-en-Y gastrojejunostomy and in an uncut Roux-en-Y gastrojejunostomy. MATENRIALS AND METHODS: 50 patients (31 men and 19 women) had a conventional Roux-en-Y reconstruction and 53 patients (35 men and 18 women) had an uncut Roux-en-Y reconstruction. The Roux stasis syndrome was defined by clinical criteria only. The criteria included one of the four following conditions at the time of follow-up: chronic upper abdominal pain, postprandial fullness, persistent nausea, and intermittent vomiting that are worsened by eating. Follow-up after surgery was done in all patients at 7~12, 13~18, 19~24, 25~30, and 31~36 months. RESULTS: According to the criteria, the Roux stasis syndrome occurred in 40.0% of the patients at 7~12 months, 33.3% at 13~18 months, 35.3% at 19~24 months, 32.0% at 25~30 months, and 33.3% at 31~36 months after a conventional Roux-en-Y operation. The syndrome occurred in 22.6% of the patients at 7~12 months, 15.2% at 13~18 months, 17.1% at 19~24 months, 19.2% at 25~30 months, and 20% at 31~36 months after an uncut Roux-en-Y reconstruction. Conclusion: In terms of occurrence pattern, only a little variance existed one year after both procedures. Comparing the Roux stasis syndrome in both procedures, the uncut Roux operation had better results than the conventional Roux operation.
Abdominal Pain
;
Eating
;
Follow-Up Studies
;
Gastrectomy*
;
Gastric Bypass*
;
Humans
;
Male
;
Nausea
;
Vomiting
10.Remote Metastasis to the Gastric Cardia in Esophageal Carcinoma: CT Findings.
Gil Jong YU ; June Sik CHO ; Kyung Sook SHIN ; Hyeon Yong JEONG ; Seung Moo NOH ; Kyu Sang SONG ; Kyung Myung SON
Journal of the Korean Radiological Society 2002;47(2):205-211
PURPOSE: To assess the CT findings of remote metastasis to the gastric cardia in patients with esophageal carcinoma. MATERIALS AND METHODS: Among patients with esophageal carcinomas treated between June 1994 and May 1999, five males aged 65-75 (mean, 67.4) years with histologically proven remote metastasis to the gastric cardia from esophageal squamous cell carcinoma, detected at surgery (n=2) or endoscopic biopsy (n=3), underwent CT scanning. We retrospectively evaluated the findings in terms of the location, size and appearance of each lesion and the presence or absence of associated lymphadenopathy. RESULTS: The primary esophageal carcinomas were located in the middle third (n=4) and lower third (n=1) of the esophagus. All five gastric metastases were solitary and occurred in the gastric cardia, and were separated from the primary tumors. CT showed that the metastases ranged in size from 4.2 to 8.0 (mean, 6.7) cm, and all were larger than the primary tumors. All were ulcerated, and in four cases there was associated abdominal lymphadenopathy. They were all well defined, poorly enhanced, submucosal masses that were endogastric in three cases and exogastric in two. The latter were difficult to differentiate from extrinsic masses compressing the gastric cardia. CONCLUSION: Our results suggest that when a submucosal gastric cardial mass with associated lymphadenopathy is detected by CT during the initial staging or follow-up evaluation of esophageal carcinoma, remote gastric metastasis should be considered.
Biopsy
;
Carcinoma, Squamous Cell
;
Cardia*
;
Esophagus
;
Follow-Up Studies
;
Humans
;
Lymphatic Diseases
;
Male
;
Neoplasm Metastasis*
;
Retrospective Studies
;
Tomography, X-Ray Computed
;
Ulcer