1.The Adequacy of a Conventional Mechanical Ventilator as a Ventilation Method during Cardiopulmonary Resuscitation: A Manikin Study.
Hong Joon AHN ; Kun Dong KIM ; Won Joon JEONG ; Jun Wan LEE ; In Sool YOO ; Seung RYU
Korean Journal of Critical Care Medicine 2015;30(2):89-94
BACKGROUND: We conducted this study to verify whether a mechanical ventilator is adequate for cardiopulmonary resuscitation (CPR). METHODS: A self-inflating bag resuscitator and a mechanical ventilator were used to test two experimental models: Model 1 (CPR manikin without chest compression) and Model 2 (CPR manikin with chest compression). Model 2 was divided into three subgroups according to ventilator pressure limits (P(limit)). The self-inflating bag resuscitator was set with a ventilation rate of 10 breaths/min with the volume-marked bag-valve procedure. The mode of the mechanical ventilator was set as follows: volume-controlled mandatory ventilation of tidal volume (Vt) 600 mL, an inspiration time of 1.2 seconds, a constant flow pattern, a ventilation rate of 10 breaths/minute, a positive end expiratory pressure of 3 cmH2O and a maximum trigger limit. Peak airway pressure (P(peak)) and Vt were measured by a flow analyzer. Ventilation adequacy was determined at a Vt range of 400-600 mL with a P(peak) of < or = 50 cmH2O. RESULTS: In Model 1, Vt and P(peak) were in the appropriate range in the ventilation equipments. In Model 2, for the self-inflating bag resuscitator, the adequate Vt and P(peak) levels were 17%, and the P(peak) adequacy was 20% and the Vt was 65%. For the mechanical ventilator, the adequate Vt and P(peak) levels were 85%; the P(peak) adequacy was 85%; and the Vt adequacy was 100% at 60 cmH2O of P(limit). CONCLUSIONS: In a manikin model, a mechanical ventilator was superior to self-inflating bag resuscitator for maintaining adequate ventilation during chest compression.
Cardiopulmonary Resuscitation*
;
Manikins*
;
Models, Theoretical
;
Positive-Pressure Respiration
;
Thorax
;
Tidal Volume
;
Ventilation*
;
Ventilators, Mechanical*
2.Neurilemmoma of Deep Peroneal Nerve Sensory Branch : Thermographic Findings with Compression Test.
Journal of Korean Neurosurgical Society 2015;58(3):286-290
We report a case of neurilemmoma of deep peroneal nerve sensory branch that triggered sensory change with compression test on lower extremity. After resection of tumor, there are evoked thermal changes on pre- and post-operative infrared (IR) thermographic images. A 52-year-old female presented with low back pain, sciatica, and sensory change on the dorsal side of the right foot and big toe that has lasted for 9 months. She also presented with right tibial mass sized 1.2 cm by 1.4 cm. Ultrasonographic imaging revealed a peripheral nerve sheath tumor arising from the peroneal nerve. IR thermographic image showed hyperthermia when the neurilemoma induced sensory change with compression test on the fibular area, dorsum of foot, and big toe. After surgery, the symptoms and thermographic changes were relieved and disappeared. The clinical, surgical, radiographic, and thermographic perspectives regarding this case are discussed.
Female
;
Fever
;
Foot
;
Humans
;
Low Back Pain
;
Lower Extremity
;
Middle Aged
;
Neurilemmoma*
;
Peripheral Nerves
;
Peroneal Nerve*
;
Sciatica
;
Toes
3.Rapid Preparation and Quality Control of 99mTc-ECD, MAG3 and MIBI using Microwave Heating and Sep-Pak Cartridges.
Seung Jun OH ; Dae Hyuk MOON ; Jin Sook RYU ; Hee Kyung LEE
Korean Journal of Nuclear Medicine 1999;33(4):430-438
PURPOSE: We evaluated a rapid preparation procedures for the labeling and quality control of 99mTc-ECD, MAG3, and MIBI using microwave heating and Sep-Pak cartridges. MATERIALS AND METHODS: 99mTc labeling of ECD, MAG3, and MIBI kit preparation was performed according to the package inserts with microwave heating modification. Heating time was 10-15 sec, and heating was performed with 3 mm plastic bottle with screw cap to prevent radiation contamination. Labeling efficiency was obtained with C18 or Alumina N Sep-Pak cartridges. RESULTS: The radiochemical purity of 93~96% for 99mTc-ECD and 95~99% for 99mTc-MIBI was obtained using Alumina N Sep-Pak cartridge. The optimum irradiation time of microwave method for 3 ml 99mTc-labeled radiopharmaceutical solution was 10 sec for 99mTc-ECD and 99mTc-MIBI, and 15 sec for 99mTc-MAG3. The RESULTS of quality control data with Sep-Pak cartridges were well correlated with TLC method. The total preparation time of these radiopharmcaeuticals was 5~6 min including quality control procedure. CONCLUSION: This study demonstrates that radiopharmaceuticals preparation by microwave heating and quality control by Sep-Pak cartridges can be efficiently utilized as an alternative to the recommended method by manufacturer's manual.
Aluminum Oxide
;
Heating*
;
Hot Temperature*
;
Microwaves*
;
Plastics
;
Product Labeling
;
Quality Control*
;
Radiopharmaceuticals
;
Technetium Tc 99m Mertiatide
4.Management of Cervical Myelopathy in Athetoid Cerebral Palsy: Case report.
Jun Sung KIM ; Keun Hyeong RYU ; Seung Han YANG
Journal of the Korean Academy of Rehabilitation Medicine 1998;22(5):1136-1140
We present two patients with a cerebral palsy who developed cervical myelopathy long from term involuntary movements. Frequently instability with a premature onset of spondylosis of the cervical spine is found in an athetoid cerebral palsy patient. These structural abnormalities appear to be related to the athetoid motion of neck in a cerebral palsy. The combination of a disk degeneration and listhetic instability with a narrow canal predisposes these patients for the relatively rapid progression to a devastating neurological defect. Early surgical management is a treatment of choice for the cervical myelopathy associated with an athetoid cerebral palsy.
Cerebral Palsy*
;
Dyskinesias
;
Humans
;
Intervertebral Disc Degeneration
;
Neck
;
Spinal Cord Diseases*
;
Spine
;
Spondylosis
5.Sacral Spinal Meningeal Cyst(Perineurial Cyst): A Case Report.
Jun Seung LEE ; Yang Wha PARK ; Ik Seung KWON ; Youn Suok RYU ; Seung Kuan HONG ; Myong Sun MOON
Journal of Korean Neurosurgical Society 1989;18(4):634-638
We experienced a rare case of sacral meningeal cyst so called sacral perineurial cyst(Tarlov cyst). A 15 years old girl was admitted to the hospital because of sudden severe low back pain and Lt. sciatica for about one week. We performed delayed myelography and spinal computeized tomographic myelography(C.T.M) for differential diagnosis. Delayed filling of contrast media in the cyst was significant in diagnosis of sacral meningeal cyst type II. Laminectomy of sacrum(S1) was performed for partial excision of cystic wall and plastic suture. Operative finding was typical sacral perineurial cyst(Tarlov cyst) which was recently clssified as sacral meningeal cyst type II. The classification of spinal meningeal cysts in the literature was indistinct and confused. We also agree with Nabors et. al, in current classificcation of spinal meningeal cysts, in which the spinal meningeal cysts, in which the spinal meningeal cysts were divided into 3 groups as extradural spinal Mcs Type I(Diverticulum), Type II(perineurial cyst), intradural spinal Mcs(arachnoid cyst).
Adolescent
;
Classification
;
Contrast Media
;
Diagnosis
;
Diagnosis, Differential
;
Female
;
Humans
;
Laminectomy
;
Low Back Pain
;
Myelography
;
Plastics
;
Sciatica
;
Sutures
6.Multistrategic Memory Training with the Metamemory Concept in Healthy Older Adults.
Jung Hae YOUN ; Jun Young LEE ; Seolmin KIM ; Seung Ho RYU
Psychiatry Investigation 2011;8(4):354-361
OBJECTIVE: According to the increase of older people, the need for effective methods to maintain or improve cognitive functions in the elderly has increased. These cognitive enhancing methods may contribute to the prevention of elderly cognitive decline by aging and dementing illness as well. This study aimed to examine the effectiveness of multistrategic memory training with the metamemory concept on cognitive functions in the normal health elderly in Korea. METHODS: The program used in this study was developed by psychiatrists and psychologists in accordance with Korean situations. We applied the training program to the community-dwelling elderly with subjective memory complaints. Twenty participants were randomly received the intervention with 20 non-treatment controls. This program consisted of 10 sessions and was administered once a week. We examined the effects of this memory training for verbal memory, visuospatial memory, working memory, and verbal fluency ability by repeated ANOVA. RESULTS: There were significant improvements in Word List Short-term Delayed Free and Cued Recall, Word list Long-term Delayed Free and Cued Recall and visuospatial recognition memory. Performance improvements in visuospatial span forwards and the Categorical Fluency Test were also significant. These improvements were still significant after adjusting for depression improvement exact categorical fluency. CONCLUSION: This study shows that multistrategic memory training with the metamemory concept may improve memory ability and other cognitive functions which are not trained and that these improvements may be achieved by pure cognitive training effects.
Adult
;
Aged
;
Aging
;
Depression
;
Humans
;
Memory
;
Memory, Short-Term
;
Psychiatry
7.The evaluation of the combined use of serum ?hCG and ultrasound in diagnosis of ectopic pregnancy.
Jong Suk KO ; Ha Bong KIM ; Myeong Suk LEE ; Hyung Sun RYU ; Ho Jun CHOI ; Seung Kwan SHIN
Korean Journal of Obstetrics and Gynecology 1993;36(7):1407-1415
No abstract available.
Diagnosis*
;
Female
;
Pregnancy
;
Pregnancy, Ectopic*
;
Ultrasonography*
8.Endovascular Coil Embolization of Intracranial Aneurysm Complicated by Heparin-Induced Thrombocytopenia.
Chang Woo RYU ; Jun Seok KOH ; Jae Seung BANG ; Eui Jong KIM
Neurointervention 2008;3(1):37-41
Heparin is commonly used to prevent and treat of thromboembolic events during the endovascular intervention. Rarely, heparin-induced thrombocytopenia (HIT), which is characterized by moderate thrombocytopenia and paradoxical vascular thromboses, complicates systemic heparinization given during endovacular procedures. We present a case of an endovascular treatement of the anterior communicating artery aneurysm complicated by HIT. This case of HIT manifested thromboembolic event and intracerebral hemorrhage simultaneously.
Aneurysm
;
Cerebral Hemorrhage
;
Embolization, Therapeutic*
;
Heparin
;
Intracranial Aneurysm*
;
Thrombocytopenia*
;
Thrombosis
9.Intervention of Nonsuicidal Self-Injury in School Counseling
Shinhye RYU ; Seung Min BAE ; Jin Yong JUN ; Woo-Young IM
Korean Journal of Psychosomatic Medicine 2022;30(1):1-6
Recently, nonsuicidal self-injury (NSSI) has been increasing considerably in school counseling. According to the Youth Counseling and Welfare Development Institute, the number of counseling support for NSSI adolescent in 2018 was more than three times higher than the previous year, and the average time when NSSI behavior first appeared was 12.43 years old. As such, adolesnect NSSI continues to increase in recent years, and the age is also gradually decreasing. Nevertheless, research on the motives and characteristics of NSSI among domestic adolescents is still insufficient. This may be attributed to the difficulty of conducting research because self-injury behavior is secretly performed. However, it is also true that this reality has another limitation in the school field, which urgently requires counseling intervention and prevention of students' mental health problems. In addition, counseling for self-injury in the school scene is the biggest cause of exhaustion for counselors because they are under very great stress to cope with repeated self-harm in the dual role of counselors and teachers in school situations. Therefore, this study examines the causes and characteristics of involuntary self-injury through previous research analysis, and examines various difficulties experienced as a school counselor, as well as the effective intervention method of non suicidal self-injury in school counseling.
10.Systemic macrophage depletion attenuates infarct size in an experimental mouse model of stroke
Seung-Won LEE ; Dong-Jun SONG ; Han-Seung RYU ; You-Sub KIM ; Tae-Sun KIM ; Sung-Pil JOO
Journal of Cerebrovascular and Endovascular Neurosurgery 2021;23(4):304-313
Objective:
Macrophages have been shown to play important roles in various pathophysiological processes of the central nervous system via neuroinflammation, leading to an increased interest in macrophage biology. Circulating blood monocytes are among the first cells to infiltrate the brain after ischemic stroke; however, the role of innate immune cells such as monocytes and macrophages remains to be elucidated. Here, we investigated the association between blood monocytes and infarct size following ischemic stroke.
Methods:
We induced stroke using a focal ischemia mouse model through middle cerebral artery suture occlusion. To deplete circulating blood monocytes, clodronate was injected intraperitoneally 24 h before the surgery. Animals were sacrificed at specified time points, and the infarct size and mRNA expression were then measured.
Results:
The clodronate-injected mice showed significantly smaller infarct size than the control mice. Immunohistochemical staining revealed that monocyte depletion significantly blocked the infiltration of macrophages and microglia. The mRNA expression levels of macrophage and microglia markers were higher in the left infarcted brain than in the right non-infarcted brain.
Conclusions
In summary, monocyte depletion reduced the infarct size and mitigated neurological deficits in mice following ischemic stroke, likely by blocking the infiltration of inflammatory cells such as macrophages and microglia.