No abstract available.
Animals ; Capsaicin* ; Colon* ; Cytokines* ; Lung* ; Melanoma, Experimental* ; Mice* ; RNA, Messenger*

A 49-year-old male was found unconscious at his accommodation and visited the emergency room. He was on antipsychotic and antidepressant drugs (vortioxetine hydrobromide, mirtazapine, sertraline hydrochloride, quetiapine, and alprazolam) for schizophrenia and major depression. At the time of discovery there were signs of overdose of the drugs around the patient. A physical examination revealed, pain, pallor, and edema in the left buttocks and lateral thigh. Active ankle movements below the left ankle were not possible and sensations in the tibia and peroneal nerves were lost. The pressure in the buttock compartment was measured at 42 mmHg. Magnetic resonance imaging revealed edema and high intensity signals in the left hip muscles and surrounding soft tissue. An emergency fasciotomy was performed and partial restoration of the lower extremity sensation and muscle strength were achieved after 24 hours.

PURPOSE: To assess the effect of oral Ginkgo biloba extract (EGB 761) on visual field in patients with normal tension glaucoma (NTG) based on the vascular theory among the machanisms of glaucomatous optic nerve damage. METHODS: A retrospective automated visual field data were obtained from Ginkgo group (20 patients, 38 eyes) and control group (20 patients, 40 eyes). Both groups underwent five Humphrey C24-2 field program over at least 4 years, and had glaucomatous optic nerve damage and visual field change, whose IOP were maintained under 21mmHg during all follow-up periods. Linear regression was performed with respect to mean deviation (MD), corrected pattern standard deviation (CPSD), and mean thresholds of Glaucoma Hemifield test (GHT). Subjects were classified as progressive, improvement, stationary based on the slope and statistical significance. RESULTS: There were 6 eyes (15.8%) with improvements with regard to MD in Ginkgo group. There were 5 eyes (13.2%) with improvements in Ginkgo group and 3 eyes (7.5%) with improvements in control group with regard to CPSD. With GHT cluster analysis, there were 13 eyes (34.2%) with improvements in Ginkgo group and 5 eyes (12.5%) with improvements in control group. CONCLUSIONS: The visual field in patient with NTG was improved in GBE group through MD, CPSD, and GHT cluster mean threshold, which was relatively compatible with known NTG visual field defect.
Follow-Up Studies ; Ginkgo biloba* ; Glaucoma ; Humans ; Linear Models ; Low Tension Glaucoma ; Optic Nerve ; Retrospective Studies ; Visual Field Tests ; Visual Fields*

We report one case of implant plate exposure after Ahmed valve implantation, treated with preserved fascia lata transplantation. Exposure of implant occurred in 47-year-old patient with Ahmed glaucoma valve implantation. She was treated with preserved fascia lata graft and amniotic membrane transplantation. No recurrent implant plate exposure has been found since then. Intraocular pressure has been maintained well for 3 months of follow-up. In cases of implant plate exposure, additional preserved fascia lata graft and amniotic membrane transplantation can improve surgical success.
Amnion ; Fascia ; Fascia Lata ; Follow-Up Studies ; Glaucoma ; Humans ; Intraocular Pressure ; Middle Aged ; Transplants

No abstract available.
Child* ; Humans ; Hypercalciuria*

PURPOSE: This study examined the effect of a self-help management program which strengthens self-efficacy on the self-efficacy and the activities of daily living(ADL) in stroke patients. METHODS: A quasi-experimental nonequivalent control group, pre and post design was used. The subjects consisted of 47 stroke patients. Twenty-six patients were assigned to the experimental group and 21 patients were assigned to the control group. The self-help management program by strengthen self-efficacy and general hospital care were carried out on the experimental group. General hospital care was performed on the control group. The data was collected before and 5 weeks after the program. All subjects were questioned about the self-efficacy and ADL before and after the program. RESULTS: The scores of the self-efficacy and ADL in the experimental group were higher than those in the control group. CONCLUSION: The self-help management program by strengthen self-efficacy is effective in increasing the self-efficacy and ADL. Therefore this program may be a useful intervention to increase the ADL in stroke patients.
Activities of Daily Living ; Hospitals, General ; Humans ; Stroke

No abstract available.
Humans ; Parents* ; Siblings*

We report two cases of progressive localized retinal nerve fiber layer (RNFL) defect following cotton wool spots and a dot hemorrhage, 63-year-old woman with RNFL defect in inferior temporal retina of the right eye and 43-year-old man with RNFL defect in superior temporal retina of the right eye. Case 1 showed a dot hemorrhage adjacent to RNFL defect in the right eye and a new slit-like localized RNFL defect in the left eye 5 months later. The visual field in the left eye demonstrated corresponding field defect 9 months later. Case 2 showed a slit-like RNFL defect starting from cotton wool spots in the right eye and corresponding visual field defect. Cotton wool spots and dot hemorrhages represented ischemic damages at the nerve fiber layer. Two noticeable cases showed the progression of RNFL defect caused by repetitive localized microvascular ischemic events, resulting in visual field loss.
Adult ; Eye ; Female ; Hemorrhage ; Humans ; Middle Aged ; Nerve Fibers ; Retina ; Retinaldehyde ; Visual Fields ; Wool

No abstract available.
Calcium* ; Fetal Blood* ; Phosphorus*

PURPOSE: To compare the accuracy and agreement of intraocular pressure (IOP) and central corneal thickness (CCT) measurements with noncontact tonometer Corvis Scheimpflug Technology (Corvis ST) versus noncontact tonometer (NCT), Goldmann applanation tonometer (GAT), rebound tonometer (RBT), and ultrasound-based corneal pachymetry (US-CCT). The secondary objective was to evaluate the corneal biomechanical values using Corvis ST tonometer in patients with glaucoma. METHODS: Thirty-one healthy participants and 47 patients with primary open angle glaucoma and normal tension glaucoma were enrolled in this study. One eye was selected randomly. In each participant, GAT, NCT, RBT, US-CCT and measurements with Corvis ST (Corvis-IOP and Corvis-CCT) were obtained. IOP and CCT measurements of each device were compared. Device agreement was calculated by Bland-Altman analysis. Additionally, corneal highest concavity parameters were compared between healthy subjects and glaucoma patients. RESULTS: Mean IOPs in all examined eyes were 13.28 +/- 2.32 mm Hg for CST, 14.71 +/- 2.95 mm Hg for GAT, 14.44 +/- 3.10 mm Hg for NCT, and 13.23 +/- 2.89 mm Hg for RBT. There was no statistical difference in IOP measurements among tonometers. Correlation analysis showed a high correlation between each pair of tonometers (all p < 0.0001). Bland-Altman plots of all devices revealed good agreement of the IOP and CCT measurements. In glaucoma patients, highest concavity time and peak distance of highest concavity parameters were statistically lower than in normal subjects (16.93 +/- 0.66 ms vs. 16.48 +/- 0.84 ms p = 0.020, 4.23 +/- 1.34 mm vs. 3.41 +/- 1.27 mm p = 0.017, respectively). CONCLUSIONS: The CST, a newly-developed tonometer with features of visualization and measurement of the corneal deformation response to an air impulse, can be considered a reliable alternative method for measuring IOP and CCT in healthy subjects and glaucoma patients. Highest concavity parameters could be another important indicator identifying corneal viscosity or elasticity in patients with glaucoma.
Corneal Pachymetry ; Elasticity ; Glaucoma ; Glaucoma, Open-Angle ; Humans ; Intraocular Pressure ; Low Tension Glaucoma ; Viscosity