1.A Morphologic Study on the Bile Duct Changes Induced by Common Bile Duct Ligation in Rats.
Jin Young JEONG ; Dae Young KANG ; Seung Moo NOH
Korean Journal of Pathology 1993;27(6):618-629
In an attempt to elucidate the pathological changes following common bile duct ligation, the present study was undertaken in male Sprague-Dawley rats. Morphologic studies of the livers were performed at 1, 2, 3, 5, 7, 9, 11, 13 and 15 weeks after common bile duct ligation. In an attempt to clarify the relationship between the process of bile duct formation and the nature of primitive cells observable around the primitive biliary structure, light microscopic, immunohistochemical and electron microscopic studies were performed. The results were noted as follows: 1) Light microscopically, proliferation of biliary cells began in the periphery of portal areas and expanded toward hepatic lobules. In severe cases of biliary structure proliferation, hepatocytic cords and classic hepatic lobules were inconspicuous. 2) Immunohistochemically, CK-19 expression was limited to biliary structures in protal areas and proliferated biliary epithelial cells. In the serial sections of paraffin block, proliferated intrahepatic biliary structures were associated with those of portal areas. Some oval cells in the ductular hepatocytes were stained for both CK-19 and MNF 116. 3) Ultrastructurally, the proliferated biliary epithelial cells divided into three patterns: absence of lumen, formation of incomplete lumen, and formation of complete lumen. Furthermore these patterns had spectral continuity of maturation in their structures. 4) In some biliary structures, individual biliary cells pushed the basement membrane toward neighboring tissue with accompanying destruction of basement membranes, patterns of budding. Sometimes these cells and hepatocytes comprised the same lumen. In summary, the results obtained by the present study indicate that proliferated biliary structures may be derived from the preexisting intralobular or portal biliary system.
Male
;
Humans
2.Clinical analysis according to reconstructive type after total gastrectomy for gastric cancer.
Seung Ho CHOI ; Sung Hoon NOH ; Jin Sik MIN ; Kyong Sik LEE ; Chun Koo KIM
Journal of the Korean Surgical Society 1991;41(6):734-743
No abstract available.
Gastrectomy*
;
Stomach Neoplasms*
3.The effect of inductive chemotheraphy with FAC regimen on breast cancer.
Eil Sung CHANG ; Young Il KIM ; Seung Moo NOH ; Jin Sun BAE ; Ki Sub SON
Journal of the Korean Surgical Society 1993;44(4):520-527
No abstract available.
Breast Neoplasms*
;
Breast*
4.Postoperative survival and prognostic factors in colorectal cancer.
Sung Hoon NOH ; Seung Ho CHOI ; Jin Sik MIN ; Kyung Sik LEE ; Choon Kyu KIM
Journal of the Korean Surgical Society 1992;42(1):87-100
No abstract available.
Colorectal Neoplasms*
5.Comparative Analysis of Cervical Arthroplasty Using Mobi-C(R) and Anterior Cervical Discectomy and Husion Using the Solis(R) -Cage.
Jin Hoon PARK ; Kwang Ho ROH ; Ji Young CHO ; Young Shin RA ; Seung Chul RHIM ; Sung Woo NOH
Journal of Korean Neurosurgical Society 2008;44(4):217-221
OBJECTIVE: Although anterior cervical discectomy and fusion (ACDF) is the standard treatment for degenerative cervical disc disease, concerns regarding adjacent level degeneration and loss of motion have suggested that arthroplasty may be a better alternative. We have compared clinical and radiological results in patients with cervical disc herniations treated with arthroplasty and ACDF. METHODS: We evaluated 53 patients treated for cervical disc herniations with radiculopathy, 21 of whom underwent arthroplasty and 32 of whom underwent ACDF. Clinical results included the Visual Analogue Scale (VAS) score for upper extremity radiculopathy, neck disability index (NDI), duration of hospital stay and convalescence time. All patients were assessed radiologically by measuring cervical lordosis, segmental lordosis and segmental range-of-movement (ROM) of operated and adjacent disc levels. RESULTS: Mean hospital stay (5.62 vs. 6.26 days, p<0.05) and interval between surgery and return to work (1.10 vs. 2.92 weeks, p<0.05) were significantly shorter in the arthroplasty than in the fusion group. Mean NDI and extremity VAS score improved after 12 months in both groups. Although it was not significant, segmental ROM of adjacent levels was higher in the fusion group than in the arthroplasty group. And, segmental motion of operated levels in arthroplasty group maintained more than preoperative value at last follow up. CONCLUSION: Although clinical results were similar in the two groups, postoperative recovery was significantly shorter in the arthroplasty group. Although it was not significant, ROM of adjacent segments was less in the arthroplasty group. Motion of operated levels in arthroplasty group was preserved at last follow up.
Animals
;
Arthroplasty
;
Convalescence
;
Diskectomy
;
Extremities
;
Follow-Up Studies
;
Humans
;
Length of Stay
;
Lordosis
;
Neck
;
Radiculopathy
;
Return to Work
;
Upper Extremity
6.Nutritional effects according to reconstructional methods after total gastrectomy.
Jin Sik MIN ; Seung Ho CHOI ; Sung Hoon NOH ; Myung Wook KIM
Yonsei Medical Journal 1995;36(1):9-14
Malnutrition and weight loss after total gastrectomy is one of the major concerns of surgeons. In order to improve the nutritional status in these patients, many surgeons have tried to restore the duodenal passage as reconstructive procedure but debates have been continued. So we investigated weight change, postprandial serum secretin response and fecal fat amount to evaluate the esophagojejunoduodenostomy after which the duodenal passage was restored. Total gastrectomized dogs showed significant weight loss and all experimental animals except sham operation died between five and eight weeks after the operation. Serum secretin concentration after esophagojejunoduodenostomy increased significantly from a mean fasting value of 100 +/- 12.5 pg/mL to a mean peak of 142 +/- 22.5 pg/mL at 40 minutes and returned to the fasting level at 120 minutes postprandially. But fasting and postprandial serum secretin concentration in patients following Roux-en Y esophagojejunostomy were fluctuated irregularly. The amount of fecal fat in esophagojejunoduodenostomy was 5.3 +/- 1.2 gm/100 gm stool, which was not different from that of the control group but in Roux-en Y esophagojejunostomy it was 28.1 +/- 4.1 gm/100 gm stool which was much higher than that observed in esophagojejunoduodenostomy and in control group. These results suggest that esophagojejunoduodenostomy is superior to Roux-en Y esophagojejunostomy in respect to pancreatic secretory function and fat absorption.
Anastomosis, Roux-en-Y
;
Animal
;
*Animal Nutrition
;
Dogs
;
Duodenostomy
;
Esophagostomy
;
*Gastrectomy
;
Jejunostomy
;
Support, Non-U.S. Gov't
7.Gastric carcinoid tumor.
Wan Soo KIM ; Seung Ho CHOI ; Sung Hoon NOH ; Jin Sik MIN ; Ho Geun KIM ; Won Ho KIM
Journal of the Korean Cancer Association 1991;23(3):596-605
No abstract available.
Carcinoid Tumor*
8.Remnant stomach cancer.
Sung Hoon NOH ; Dong Sup YOON ; Seung Ho CHOI ; Jin Sik MIN ; Jae Kyung ROH ; Byung Soo KIM
Journal of the Korean Cancer Association 1991;23(3):578-585
No abstract available.
Gastric Stump*
9.The Single Incision Laparoscopic Intragastric Wedge Resection of Gastric Submucosal Tumor.
Jin Uk NA ; Sang Il LEE ; Seung Moo NOH
Journal of Gastric Cancer 2011;11(4):225-229
PURPOSE: Laparoscopic wedge resection of gastric submucosal tumor may be difficult in case of the endophytic mass or the mass located unreachable area such as cardia, and intragastric approach can be useful. We would present the experiences of the intragastric wedge resection. MATERIALS AND METHODS: There were 7 patients diagnosed as gastric submucosal tumor and underwent the intragastric wedge resection at Surgery, Chungnam National University Hospital. We reviewed medical record. RESULTS: There were 3 male and 4 female. Mean age was 65 years-old (57~73). Mean body mass index was 26.28 kg/m2 (21.28~35.30). Location of lesions was 4 cardia, 2 fundus and 1 midbody, respectively. Mean operation time was 83.6 minutes (70~105). All patients were healed without any complication. Mean postoperative hospital stay was 5.4 days (4~6). Mean size was 2.7 cm (2.3~3.8). Pathologic finding was 5 gastrointestinal stromal tumor and 2 leiomyoma. CONCLUSIONS: The single incision intragastric wedge resection of gastric submucosal tumor is feasible and acceptable, especially in mass of gastric upper part.
Body Mass Index
;
Cardia
;
Female
;
Gastrectomy
;
Gastrointestinal Stromal Tumors
;
Humans
;
Laparoscopy
;
Length of Stay
;
Male
;
Stomach Neoplasms
;
Surgical Procedures, Minimally Invasive
10.Anterior Cruciate Ligament Reconstruction through the Patellar Tendon Harvest Site.
Woo Shin CHO ; Kyoung Min NOH ; Yong Sun CHO ; Ho Seung LEE ; Chung Hwan KIM ; Hoi Jin LEE
The Journal of the Korean Orthopaedic Association 1998;33(7):1720-1727
Arthroscopy assisted anterior cruciate ligament(ACL) reconstruction with the autogenous bone-patellar tendon-bone(BPB) graft showed more favorable results in the hand of experienced surgeon, but it requires long leaming curve for skillful techniques. On the contrary, open method is very easy to learn, but it needs more soft tissue dissection affecting rehabilitation and morbidity. Arthrotomy through the patellar tendon harvest site provide good surgical approach without supplementary incision, and hence short operation time and good clinical result can be expected. The purpose of this study is to introduce this technique and compares the results with arthroscopic one. We performed 67 cases of ACL reconstruction with autogenous BPB graft through the patellar tendon harvest site. We recorded and analysed the physical findings, Lysholm score and Cybex test at preoperative and postoperative 3, 6, 12 months. Average Lysholm score was 58.0 preoperatively and 90.5 at postoperative one year. Cybex test at one year follow-up showed decreased muscle strength of quadriceps, which was nearly the same result with arthroscopic technique. In conclusion, this technique provided similar excellent clinical results comparing with the arthroscopy assisted ones. Furthermore, this technique had merits of short learning curve and short operation time.
Anterior Cruciate Ligament Reconstruction*
;
Anterior Cruciate Ligament*
;
Arthroscopy
;
Follow-Up Studies
;
Hand
;
Learning Curve
;
Muscle Strength
;
Patellar Ligament*
;
Rehabilitation
;
Transplants