BACKGROUND: According to the 1992 version of ACLS guideline, adenosine is recommended as the first line drug far the treatment of paroxysmal supraventricular tachycardia(PSYT). But adenosine is not used frequently in our country, despite currency proven effect and safety. Therefore we tried to compare the efficacy and safety of adenosine with verapamil for the treatment far PSVT. MATERIALS AND METHODS: We prospectively reviewed charles of PSVT patients admitted to YongDong Severance Hospital from Jan. 1995 to Dec. 1996. These patients were randomly divided into two groups. The flat group was given 6mg of adenosine initially, and another 12mg was given within 5 minutes if fast dose failed. The other group was given 5mg of verapamil initially, and if failed, 10mg was given within 10 minutes. The results were analyzed by Chi-square test and student-t method. RESULTS: In converting PSVT to normal rhythm, adenosine and verapamil showed similar results and there was no difference between the two Groups in frequency of side elects, but serious arrhythmia such as ventricular fibrillation and ventricular tachycardia was not seen in the adenosine group. CONCLUSION: Adenosine not only showed comparable effect and safety, but also had shorter action time than verapamil. Therefore we recommand adenosine, as a safe and effective fort line drug for PSVT.
Adenosine* ; Arrhythmias, Cardiac ; Humans ; Prospective Studies ; Tachycardia, Supraventricular* ; Tachycardia, Ventricular ; Ventricular Fibrillation ; Verapamil*

No abstract available.
Aneurysm*

No abstract available.
Colon* ; Diverticulitis* ; Laparoscopy*

PURPOSE:Varying clinical phenotypes are associated with the chromosome 22q11.2 microdeletion syndrome. The endocrine manifestation are latent or overt hypoparathyroidism, thyroid dysfunction and short stature. This study was undertaken to investigate frequencies of endocrine abnormalities and short stature in patients with the chromosome 22q11.2 microdeletion syndrome. METHODS:Forty three unrelated patients were diagnosed having chromosome 22q11.2 microdeletion syndrome. Chromosomal microdeletion was confirmed by fluorescent in situ hybridation (FISH) with DNA probe (22q11.2 LSI TUPLE1 from Vysis). Serum total calcium and intact parathyroid hormone (PTH) were measured in all patients. Thyroid function tests including free thyroxine(T4), thyroid stimulating hormone (TSH) and thyroid autoantibodies were performed in all patients. Insulin-like growth factor-1 (IGF-1) was measured in 10 patients. Height, weight and body mass index were compared with chronological age in all patients. RESULTS:Seven patients (16%) had an overt hypoparathyroidism, presenting with hypocalcemic tetany. Thirteen patients (31%) showing hypocalcemia with normal PTH were regarded as having latent hypoparathyroidism since their PTH secretion response was blunted. Out of 2 patients with thyroid diseases, one patient had Graves disease and the other had Hashimoto thyroiditis. Five patients (12%) were below the 3rd percentile in height at evaluation. The BMI was below the 5th percentile in 23% of patients. CONCLUSION: Twenty patients (47%) presented with overt and latent hypoparathyroidism. Interestingly, autoimmune thyroid diseases such as Graves disease and Hashimoto thyroiditis were associated in patients with chromosome 22q11.2 microdeletion, indicating predisposition to autoimmune disorders. Therefore, a careful endocrine and growth evaluation is needed in these patients.
Autoantibodies ; Body Mass Index ; Calcium ; DNA ; Graves Disease ; Hashimoto Disease ; Humans ; Hypocalcemia ; Hypoparathyroidism ; Parathyroid Hormone ; Phenotype ; Tetany ; Thyroid Diseases ; Thyroid Function Tests ; Thyroid Gland ; Thyrotropin

No abstract available.
Colorectal Neoplasms* ; Humans ; Male*

Cyanide intoxication results in severe metabolic acidosis and catastrophic prognosis with conventional treatment. Indications of extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT) are expanding to poisoning cases. A 50-year-old male patient arrived in the emergency room due to mental change after ingestion of cyanide as a suicide attempt 30 minutes prior. He was comatose, and brain stem reflexes were absent. Initial laboratory analysis demonstrated severe metabolic acidosis with increased lactic acid of 25 mM/L. Shock and acidosis were not corrected despite a large amount of fluid resuscitation with highdose norepinephrine and continuous renal replacement therapy. We decided to apply ECMO and CRRT to allow time for stabilization of hemodynamic status. After administration of antidote infusion, although the patient had the potential to progress to brain death status, vital signs were improved with correction of acidosis. We considered the evaluation for organ donation. We report a male patient who showed typical cyanide intoxication as lethal metabolic acidosis and cardiac impairment, and the patient recovered after antidote administration during vital organ support through ECMO and CRRT.
Acidosis ; Brain Death ; Brain Stem ; Coma ; Cyanides ; Eating ; Emergency Service, Hospital ; Extracorporeal Membrane Oxygenation* ; Hemodynamics ; Humans ; Lactic Acid ; Male ; Middle Aged ; Norepinephrine ; Organ Transplantation ; Poisoning ; Prognosis ; Reflex ; Renal Replacement Therapy* ; Resuscitation ; Shock ; Suicide ; Tissue and Organ Procurement ; Vital Signs

No abstract available.
Humans ; Infant, Newborn ; Infant, Premature* ; Nephroma, Mesoblastic* ; Ultrasonography, Prenatal*

No abstract available.
Thanatophoric Dysplasia*

PURPOSE: To determin whether radiographic assessment of patella position abnormalities (such as patella altaor baja) using the 'patellar tendon : patella ratio' (Insall & Salvati's method) can be applied to flexion andextension sagittal MR images of the knee MATERIALS AND METHODS: Both flexion (55-90 degrees, mean 62 degrees) and extensionT2-weighted sagittal images of 58 knees (54 patients;age:19-72 years:M:F=40:18 were obtained and reviewed by meansof routine lateral radiographs (flexion of knees:30-60 degrees). Patellar tendon and diagonal length were measured onroutine radiographs and on flexion and extension MR images;length was measured by sagittal T2-weighted MR imagingfrom the inner aspect of patellar insertion to the inner asspect of tibial insertion, an approach whichdemonstrated the even thickness of the patellar tendon and the greastest diameter of the patella. Usingcorrelation analysis, the ratio of patellar tendon to diagonal length was compared between examination methods andbetween the non-wavy and wavy forms of patellar tendon. RESULTS: The mean length of the respectirely, 'patella,patellar tendon and patellar tendon to patella ratio' were 4.15+/-0.38, 4.04+/-0.49 and 0.9+/-0.12, respectively, onroutine radiographs; 4.32+/-0.36, 3.8+/-0.47 and 0.89+/- 0.12, respectively, on flexion MR images;and 4.3+/-0.36,3.93+/-0.44 and 0.92+/-0.12, respectively on extension MR images. Between these three different modes of assessment,a high degree of correlation of mean patella length (r=0.89-0.92) and of mean patellar tendon length (r=0.71=0.85)were found. In addition, correlation of 'patella to patellar tendon ratios' was excellent : radiographs andflexion MRimages(r=0.76);radiographs and extension MR images(r=0.76);flexion and extension MR images(r=0.84).According to the form of patellar tendon, radiographs correlated better with extension MR images (r-0.71) thanwith flexion images (r=0.62) in the non-wavy form of patellar tendon, whereas in the wavy form, correlation withflexion images (r=0.83) was better than with extension images(r=0.78). CONCLUSION: MR asessment of 'patellartendon to patella ratio's correlated well with radiographic assessment, and the latter can therefore be used forthe evaluation of abnormal patellar position. Radiographs correlated better with extension MR images in thenon-wavy form of patellar tendon, whereas in the wavy form, correlation with flexion images was better.
Knee ; Magnetic Resonance Imaging* ; Patella* ; Patellar Ligament* ; Tendons

No abstract available.
Chancre* ; Eczema* ; Nipples*