No abstract available.
Esophagus* ; Melanoma*

BACKGROUND: The laparoscopic cholecystectomy has become the treatment of choice for the majority of patients with cholecystopathy. The objectives of this study were to evaluate the safety and the efficacy of the laparoscopic cholecystectomy by reviewing of the case histories of three hundred ten consecutive patients treated with a laparoscopic cholecystectomy. METHODS: We retrospectively analyzed the initial 310 laparoscopic cholecystectomies performed at the Department of General Surgery, Sun General Hospital, from May 1993 to December 1998. Sex, age, associated diseases, previous history of abdominal operation, duration of operation, reason for conversion to open cholecystectomy, hospital stay, and postoperative complications were analyzed. RESULTS: The postoperative diagnosis was chronic cholecystitis in 213 patients, acute cholecystitis in 53 patients, cholesterolosis in 17 patients, gallbladder (GB) empyema in 13 patients, acalculous cholecystitis in 9 patients, and gallbladder carcinomas in 3 patients. The common associated diseases were diabetes mellitus and hypertension. The mean durations of operation, diet, and hospital stay were 77.6 minutes. 1.2 days, and 5 days, respectively. The mean numbers of drainages and injected analgesics were 0.8 and 1.6, respectively. Conversion to an open cholecystectomy was necessary in 8 of the 310 patients (2.6%) who underwent a laparoscopic cholecystectomy either because of severe adhesion (n=6), difficulty with anatomic identification in Calot's triangle (n=1), or severe GB empyema (n=1). The overall postoperative complication rate was 2.6% (8/310). A laparotomy was not required for the treatment of bleeding (5 cases) and residual stones (2 cases). There was no bile duct injury. One patient who had a cerebral infarction died of a cerebrovascular accident. CONCLUSION: We conclude that for benign cholecystopathy the laparoscopic cholecystectomy can be safe and feasible treatment with low morbidity.
Acalculous Cholecystitis ; Analgesics ; Bile Ducts ; Cerebral Infarction ; Cholecystectomy ; Cholecystectomy, Laparoscopic* ; Cholecystitis ; Cholecystitis, Acute ; Diabetes Mellitus ; Diagnosis ; Diet ; Empyema ; Gallbladder ; Hemorrhage ; Hospitals, General ; Humans ; Hypertension ; Laparotomy ; Length of Stay ; Postoperative Complications ; Retrospective Studies ; Solar System ; Stroke

No abstract available.

BACKGROUND: Photodynamic therapy(PDT) is a type of photochemotherapy that is designed to kill targeted tumor cells. OBJECTIVE: The Clinical effects of PDT were analysed for response rates, post-treatment healing and adverse effects on several cutaneous carcinoma in situ. METHOD: PDT with topical 5-aminolevulinic acid-based irradiation of corresponding 630+5nm light was performed in 6 carcinoma in situ patients who had actinic keratosis, Bowen' disease or cutaneous squamous cell carcinoma. RESULT: In all patients the clinical results were exellent with respect to initial complete responses and cosmetic outcome. CONCLUSION: PDT might be chosen as a first line treament for cutaneous carcimoma in situ.
Carcinoma in Situ* ; Carcinoma, Squamous Cell ; Humans ; Keratosis, Actinic ; Photochemotherapy* ; Skin*

No abstract available.
Syphilis, Congenital*

Fordyce's disease is a condition known as ectopically located sebaceous glands on the vermilion borders of the lips and oral mucosa. Clinically, it is groups of minute, yellowish, globoid macules and papules. Histologically, it is characterized by sebaceous glands not associated with hair follicles. We report on a 40-year-old man with Fordyce's disease showing particularly wide distribution on the buccal mucosa and upper lip.
Adult ; Hair Follicle ; Humans ; Lip ; Mouth Mucosa ; Sebaceous Glands

Trichilemmal horn(trichilemmal keratosis) is a rare keratinizing tumor that resembles a cutaneous horn. Histologically, it is characterized by an abrupt maturation of keratinocytes into lamellar keratin without the formation of a granular layer. We describe a case of a trichilemmal horn on the right cheek of a 78-year-old woman.
Aged ; Animals ; Cheek ; Female ; Horns* ; Humans ; Keratinocytes

This study represents the radiologic, histologic features & clinical analysis of hyaline mambrane disease in 47 newborn infants who were delivered in Ewha Womans Univ. Hospital & expired caused by repiratory distress & confirmed by autopsy , during Jan. 1981 to June, 1984. The results were as follows; 1. Classification ofradiolgraphic stage (by Wolfson's criteria); Stage III(34.1%) was the most frequent. 2. Male to female ratio was 2.4:1. 3. Method of delivery; Cesarean section (44.7%) was the highest frequency, compared with percent ofcesarean section to total delivery(29.0%). 4. Distribution of birth weight; 1.0-2.0 Kg(48.9%) was the mostfrequent. 5. Distribution of gestational period; 32-36 weeks (29.8%) was the most frequent. 6. Complication; Pulmonary hemorrhage(31.9%) was the most frequent, in order, subarachnoid hemorrhage & pneumothorax were followed.7. Final diagnosis of hyaline membrane disease was based on histo-pathologic diagnosis.
Autopsy ; Birth Weight ; Cesarean Section ; Classification ; Diagnosis ; Female ; Humans ; Hyalin ; Hyaline Membrane Disease ; Infant, Newborn ; Infant, Newborn ; Male ; Methods ; Pneumothorax ; Pregnancy ; Subarachnoid Hemorrhage

The goals of treatment in the injuries of posterior cruciate ligament(PCL) are restoration of normal tibiofemoral stability and reduction of long term osteoarthrosis of the knee. The purpose of this study is to analyze the factors on posterior stability and functional result after PCL reconstruction. From March 1996 to April 1997, twenty operation on PCL reconstruction were carried out in our hospital. The functional results according to the criteria of the Lysholm knee score and stress radiograph for posterior stability were evaluated. The average functional results evaluated by Lysholm knee score was 87. There was no significant difference in functional result according to selected grafted material, combined knee injury, type of injury and arthrotomy, etc. Difference in posterior tibial translation on average were 2.8mm in acute and 7.7mm in chronic injury. In posterolateral combined injury, average posterior tibial translation in pos- terolateral repair was 3.2mm and in posterolateral reconstruction was 9.4mm. In PCL reconstruction using hamstring with repair of PCL remnant was 2mm. In conclusion, to obtain the good result on posterior sta- bility, early PCL reconstruction using hamstring with repair of PCL remnant, and appropriate treatment on combined posterolateral injury were recommended.
Knee ; Knee Injuries ; Osteoarthritis ; Posterior Cruciate Ligament* ; Transplants

Purpose: In the present study, the efficacy and safety of brolucizumab in refractory polypoidal choroidal vasculopathy (PCV) patients treated with aflibercept were investigated. Methods: The medical records of patients with refractory PCV treated with aflibercept were reviewed. All patients had subretinal fluid or intraretinal fluid followed by at least three consecutive injections of aflibercept on a 4–8-week dosing schedule before switching to brolucizumab. Changes in injection intervals, optical coherence tomography (OCT), and OCT angiography parameters including central macular thickness (CMT), subfoveal choroidal thickness (SFCT), polyp height, lesion area, flow density, and polyp regression rate were evaluated before and 6 months after switching to brolucizumab. Results: The study included 32 eyes of 32 patients with PCV who received brolucizumab injections as switch therapy and were followed at 6 months. After switching to brolucizumab, 53% of eyes had dry macula and the injection interval was extended from 5.4 ± 1.7 weeks to 10.8 ± 2.9 weeks. Best-corrected visual acuity remained stable over the 6 months (p = 0.166). CMT and SFCT were reduced at 6 months after switching to brolucizumab (p = 0.042 and p = 0.023, respectively). Polyp regression was complete in 12.5% and partial in 62.5% of eyes. The largest polyp height and lesion size significantly decreased (p = 0.035 and p = 0.010, respectively). However, significant difference was not found regarding flow density after switching to brolucizumab (p = 0.145). Intraocular inflammation-related adverse events were not reported. Conclusions Brolucizumab could provide additional benefits in refractory PCV treated with aflibercept by reducing leakage from polyps, branching vascular networks, and choroid.