1.A Case of MELAS Syndrome.
Ki Joong KIM ; Yong Seung HWANG ; Young In CHOI ; Sung Hye PARK ; Je Geun CHI
Journal of the Korean Pediatric Society 1990;33(11):1586-1592
No abstract available.
MELAS Syndrome*
2.MRI-guided Stereotactic Thalamotomy for Cerebral Palsy Patients of Mixed Dyskinesia.
Journal of Korean Neurosurgical Society 1996;25(2):352-359
A few neurosurgical alleviate to alleviate some dyskinesias of cerebral palsy(CP) have been tried. For the spastic and tremor type, the selective posterior rhizotomy and thalamotomy are regarded as treatments of choice but other dyskinesias remains a tough challenge. The authors have performed 48 cases of MRI-guided stereotactic thalamotomy(MGST) in 37 CP patients with mixed dyskinesias from Jun. '92 to Jan. '95 using CRW stereotactic frame and MRI, without any ventriculogram. Depending upon the types of main dyskinesias, the target including ventrolateral nucleus of thalamus or medial nucleus of globus pallidus was(were) selected. Clinical results were verified in terms of preoperative symptoms improvement and patient's satisfaction. In athetoid(42 MGSTs in 32CPs) : excellent 6, good 26, fair 10, and in dystonia(30 MGSTs in 23 CPs): excellent 2, good 18, fair 10, and in spasticity(20 in 17 CPs): excellent 3, good 12, fair 5, and in choreoor choreoathetoid(7 in 6 CPs) : good 5, fair 2. Recurrence of symptoms after operation was noted in 6 cases(12.5%). Postoperative morbidity including motor weakness, speech disturbance, swallowing difficulty, and sensory abnormality were transiently noted in 9 cases(18.8%). It is the authors observation that MGST seems to be one of the beneficial procedures for relieving symptoms of CP with mixed dyskinesias.
Cerebral Palsy*
;
Deglutition
;
Dyskinesias*
;
Globus Pallidus
;
Humans
;
Magnetic Resonance Imaging
;
Muscle Spasticity
;
Recurrence
;
Rhizotomy
;
Thalamus
;
Tremor
3.Subconjunctival Orbital Fat Prolapse.
Woong Chul CHOI ; Je Seung LEE
Journal of the Korean Ophthalmological Society 2000;41(7):1609-1613
Subconjuctival orbital fat prolapse is a disease, which can be diagnosed by clinical manifestations and treated with simple procedure. Intraconal fat prolapses through weakened tenon and protrudes into subconjunctival space. The mass shows convex anterior margin and places at superotemoral region. The mass shrinks when indented and enlarges by putting pressure on the globe. It is frequently seen on males over 60 years old. It usually occurs bilaterally, and does not seem to be in association with obesity. Computer tomography and magnetic resonance image of the orbit show the mass contiguous to intraconal fat. Partial excision with careful hemostasis is sufficient for treatment.
Hemostasis
;
Humans
;
Male
;
Middle Aged
;
Obesity
;
Orbit*
;
Prolapse*
4.Intrapulmonary synovial sarcoma: A case report.
Jae Seung SHIN ; Jae Joon HWANG ; Young Ho CHOI ; Hark Je KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(9):726-729
No abstract available.
Sarcoma, Synovial*
5.Production of the monoclonal antibody and the genomic library of helicobacter pylori.
Kwang Ho RHEE ; Woo Kon LEE ; Seung Chul BAIK ; Myung Je CHO ; Hyu Jin CHOI
Journal of the Korean Society for Microbiology 1991;26(4):305-316
No abstract available.
Genomic Library*
;
Helicobacter pylori*
;
Helicobacter*
6.Undercorrection of the Thoracolumbar Kyphotic Deformity in the Osteoporotic Spine Fractures.
Yong Ho KANG ; Ho Seung JEON ; Seung Ju JEON ; Je Ho CHOI ; Seung Kyu ROH
Journal of Korean Society of Spine Surgery 2005;12(1):63-68
STUDY DESIGN: A retrospective study. OBJECTIVES: To assess the efficiency of undercorrection and transpedicular screw fixation through a posterior approach in osteoporotic spine fractures with a thoracolumbar kyphotic deformity. SUMMARY OF LITERATURE REVIEW: The surgical treatment of osteoporotic spine fractures with a thoracolumbar kyphotic deformity requires extensive surgical procedures to obtain complete restoration of the sagittal alignment, but it has a few technical limitations due to insufficient mechanical stability at the bone-screw interface. A special strategy is essential for transpedicular screw fixation for osteoporotic spine fractures with a thoracolumbar kyphotic deformity. MATERIALS AND METHODS: We reviewed 14 osteoporotic spine fracture cases, with a thoracolumbar kyphotic deformity, which had undergone undercorrection and transpedicular screw fixation through a posterior approach, between March 2000 and June 2003, with an average follow-up period of 15. 2 months. According to the Jikei grade of the osteoporosis, 9 and 5 cases were grades 2 and 3, respectively. As a radiographic assessment, we measured the kyphotic angles of the fused segments on the preoperative, postoperative and last follow up thoracolumbar lateral views on standing using Cobb's method, and also assessed the kyphotic angle correction (KAC). The clinical results were evaluated at the last follow-up. RESULTS: The kyphotic angles at the preoperative, postoperative and last follow-up were 33.5 degrees +/- 9.3, 22.4 degrees +/- 6.9 and 24.7 degrees +/- 6.8, respectively. We obtained a mean KAC gain of 11.1 degrees postoperatively (p<0.05), but a loss of 2.3 degrees at the last follow-up (p>0.05). The clinical results were analyzed as good, fair and poor in 8, 5 and 1 case, respectively. Fusions were achieved in all cases. CONCLUSIONS: Undercorrection and transpedicular screw fixation for a thoracolumbar kyphotic deformity in osteoporotic spine fractures can be one of the alternatives to avoid fixation failure and an extensive surgical procedure.
Congenital Abnormalities*
;
Follow-Up Studies
;
Kyphosis
;
Osteoporosis
;
Retrospective Studies
;
Spine*
7.Effects of a Protein Synthesis Inhibitor on Hippocampal Neuronal Damage of Rats in the Ventricular Fibrillation Cardiac Arrest Model.
Dong Rul OH ; Jang Seong CHAE ; Seung Hyun PARK ; Se Kyung KIM ; Se Min CHOI ; Je Young PARK
Journal of the Korean Society of Emergency Medicine 2000;11(4):411-420
BACKGROUND: The goal of successful resuscitation is not only to stop the process of ischemia as soon as possible but also to overcome the secondary injury process after resuscitation, which involves a complex interplay of mechanisms. Brain damage accompanying cardiac arrest and resuscitation is frequent and devastating. Cells die by one of two mechanisms: necrosis or delayed neuronal death. Delayed neuronal death may require protein synthesis. Neurons in the CA1 subfield of the hippocampus are selectively vulnerable to death after injury by ischemia and reperfusion. Death of these neurons occurs after an interval of 1 or 2 days. We assessed the effects of a protein synthesis inhibitor, cycloheximide(CHX), on hippocampal neuronal death of rats by using the ventricular fibrillation cardiac arrest(VFCA) model. METHODS: The effect of CHX(3mg/kg, s.c.) on hippocampal neuronal death was studied in two groups of 18 rats each, one group being subjected to a 2-min VFCA and the other to a 3-min VFCA. Each group was divided into three subgroups: control(group I,II) without subcutaneous injection of CHX, 'exp-12' of group I/II treated with CHX 12 hours after return of spontaneous circulation (ROSC), and 'exp-24' of group I/II treated with CHX 24 hours after ROSC. The coronal sections of the hippocampus levels were stained with hematoxylin-eosin after 72 hours of survival. The histologic damage score(HDS) was used to assign a score to the total number of damaged neurons counted in each of the hippocampal CA1 subfields. RESULTS: 1. There were not significan differences in heart rates, blood pressures, blood sugar, and blood gas in group I & II during the pre-arrest steady state or at 5 min and 30 min after ROSC. 2. In group I & II, the HDS, were significantly reduced in rats(I exp-12, 1.1+/-0.6; I exp-24, 1.3+/-0.5; II exp-12, 1.4+/-0.7; and II exp-24, 1.8+/-0.8) treated with CHX 12 hours or 24 hours after ROSC than control rats(I, 2.5+/-0.9, II, 2.9+/-0.8)(p<0.05). CONCLUSION: These results suggest that delayed hippocampal neuronal death from ischemic insult after ventricular fibrillation cardiac arrest followed by resuscitation can be prevented by a protein synthesis inhibitor, CHX. Further experimental studies of the action mechanism of protein synthesis inhibitors to delayed neuronal death and clinical applications are required.
Animals
;
Blood Glucose
;
Brain
;
Heart Arrest*
;
Heart Rate
;
Hippocampus
;
Injections, Subcutaneous
;
Ischemia
;
Necrosis
;
Neurons*
;
Protein Synthesis Inhibitors
;
Rats*
;
Reperfusion
;
Resuscitation
;
Ventricular Fibrillation*
8.Clinical Results According to the Level and Extent of Sympathetic Block in Palmar Hyperhidrosis.
Jung Hun OH ; Seung Il PARK ; Hyoung Gon JE ; Hyun Jo KIM ; Dong Kwan KIM ; Kwang Hyun SHON ; In Cheol CHOI
The Korean Journal of Thoracic and Cardiovascular Surgery 2000;33(10):817-822
BACKGROUND: Video assisted thoracic sympathectomy or sympathicotomy is a safe and effective therapy for the treatment of palmar hyperhidrosis with immediate symptomatic imporvement. However the degree of satisfaction may diminish with time due to cmpensatory sweating or excessive hand dryness. Therefore by comparing and assessing the degree of symptomatic improvement or compensatory sweating following sympathectomy or sympathicotomy at various levels we aim to determine the optimal level of sympathetic nerve block which will result in minimal side effects and maximal benefit. MATERIAL AND METHOD: Among 194 patients having undergone video assisted thoracic sympathectomy or sympathicotomy between January 1996 and June 1999, 137 patients who responded to either telephone interview or questionnaire were included in the current study. The patients were divided into three groups. Group I(n=61) ; patients having undergone T2,3,4 sympathectomy group II(35) ; patients having undergone T2 sympathicotomy and group III(41) ; patients having undergone limited T2 sympathicotomy which consist of block of interganglionic neuronal fiber on the third rib. The parameters studied comprised of pre- and post-operative palmar temperature change treatment satisfaction the degree of compensatory sweating or discomfort from palmar dryness postoperative complication and changes in plantar sweating. RESULT: There was no difference in age and sex among the groups and the mean postoperative elevation in palmar temperature was 21.59degrees C without any differences among the groups. Patients expressing satisfaction were 65.6%, 62.9% and 90.24% in groups I, II and III, respectively(p<0.05) Moderate to severe compensatory sweating was present in 65.6% 51.4%, and 24.39%, in group I, II, and III, respectively (p<0.05) Slight but comfortable amount of palmar humidness was expressed in decreasing order group III(41.6%) group I(24.6%) and group II(5.7%) (p<0.05) Ineffectiveness or recurrence was present in 5patients in group I(8.2%) 1 patient in group II(2.9%) and none in group III. With regards to plantar sweating decrease in sweating was expressed in 43 patients(31.4%) while similar degree of sweating in 61 patients(44.5%) and increase in sweating in another 33 patinets(24.1%). CONCLUSION: Limited T2 sympathicotomy resection of the lower interganglionic neuronal fiber of the second sympathetic ganglion on the third rib showed immediate effect in palmar hyperhidrosis and caused lesser compensatory sweating and hand dryness.
Autonomic Nerve Block
;
Ganglia, Sympathetic
;
Hand
;
Humans
;
Hyperhidrosis*
;
Interviews as Topic
;
Neurons
;
Postoperative Complications
;
Surveys and Questionnaires
;
Recurrence
;
Ribs
;
Sweat
;
Sweating
;
Sympathectomy
9.Demographic characteristics and family function among shift-workers.
Sung Ho HONG ; Je Myoung CHAE ; Hong Chi KIM ; Myo Kyoung CHOI ; Choo Yon CHO ; Tak Seung NAM
Journal of the Korean Academy of Family Medicine 1992;13(8):709-718
No abstract available.
Humans
10.A Case of Adrenomyeloneuropathy.
Seung Han SUK ; Young Ho SOHN ; Young Chul CHOI ; Jin Soo KIM ; Je Geun CHI
Journal of the Korean Neurological Association 1991;9(2):262-268
A 19 yar-old male patient was admitted to the department of neurology in Severance hospital beause of slowly progressive spastic paraparesis. On examination, dark brown skin color, sparse hair, spastic weakness and hypesthesia of lower extremities were noted. The laboratory studies showed high serum ACTH level with lowest normal limit of serum cortisol level. Brain MRI scan revealed high signal intensities in bilateral corticospinal tracts on T, Weighted images with gadolinium enhancement and T2eighted images. The results of three modal evoked potential studies(SEP. BAEP. VEP) were abnormal bilaterally. Nerve conduction studies and sural nerve biopsy suggested the presence of peripheral neuropathy.
Adrenocorticotropic Hormone
;
Adrenoleukodystrophy*
;
Biopsy
;
Brain
;
Evoked Potentials
;
Gadolinium
;
Hair
;
Humans
;
Hydrocortisone
;
Hypesthesia
;
Lower Extremity
;
Magnetic Resonance Imaging
;
Male
;
Muscle Spasticity
;
Neural Conduction
;
Neurology
;
Paraparesis, Spastic
;
Peripheral Nervous System Diseases
;
Pyramidal Tracts
;
Skin
;
Sural Nerve