1.Selective pulsed dye laser thrombus ablation : Can contrast media replace fiberoptics in pulsed dye laser delivery system?.
Korean Circulation Journal 1993;23(3):408-414
BACKGROUND: The absorption coefficient of the arterial thrombus is 7~10 fold greater than that of arterial wall for the wave lengths of 480~510nm. This fact suggest that selective laser thrombus ablation could be possible without ablation of surrounding vessel wall in this wavelengths. METHODS: Pulsed dye laser(488nm, 2.2micros, 10Hz) thrombus ablation was investigated in viro. Ablation threshods of whole blood clot and normal aortic tissue were measured using a 1.5mm multifiber laser catheter(14x150microm). Whole blood clot samples were lasered to determine the ablation efficiency. The operative fluence was 80mJ/mm2. The transmission efficiencies of 488nm wave length through various transmission media(including contrast media of saline solution) were observed using a upsilon Fr arterial sheath filled with transmission medium. RESULTS: The ablation threshold for fresh whole blood clot in saline solution was 36.5+/-2.4mJ/mm2(9.0+/-0.6mJ/pulse) as compared with that for normal human aortic tissue which was over 405mJ/mm2(>100mJ/pulse)(p<0.05). Pulsed dye laser ablated whole blood clot with the efficiency at 0.026+/-0.009gm/J. The role of thrombus ablation was 0.154+/-0.056gm/min. This experiment also revealed that cotrast media(Ultravist(R) 370, Schering, France) allows light tramission of 488nm wave length at relatively high efficiency. CONCLUSIONS: These facts suggested that selective pulsed dye laser ablation of fresh intravascular thrombi can be obtained at relatively low energy fluence without damaging the surrounding vascular tissue. A new pulse dye laser delivery system such as catheter system or native coronary artery filled with contrast media, which has large area of frontfiring face, may facilitate a safe and effective thrombus ablation.
Absorption
;
Catheters
;
Contrast Media*
;
Coronary Vessels
;
Humans
;
Lasers, Dye*
;
Sodium Chloride
;
Thrombosis*
2.Recent Trend and Status of Radiation Oncology Infrastructures of China and Japan.
The Journal of the Korean Society for Therapeutic Radiology and Oncology 2008;26(1):74-75
No abstract available.
3.Fractionated Stereotactic Radiation Therapy.
Journal of the Korean Medical Association 1997;40(1):122-127
No abstract available.
4.Oral Pharmacotherapy for Erectile Dysfuction.
Journal of the Korean Medical Association 1999;42(2):124-131
No abstract available.
Drug Therapy*
5.Androgens and Sexual Function and Mood.
Korean Journal of Andrology 1998;16(1):17-19
No abstract available.
Androgens*
6.Androgens and Sexual Function and Mood.
Korean Journal of Andrology 1998;16(1):17-19
No abstract available.
Androgens*
7.Molecular Cloning of Human 14-3-3 cDNA with CD3 Zeta Peptide Containing Phosphosering Tag.
Korean Journal of Immunology 1998;20(3):317-323
14-3-3 proteins are highly conserved proteins of about 29 kDa and have a minimum of seven isoforms. 14- 3-3 proteins interact with many signalling proteins by the recognition of phosphoserine. For the identification of proteins which react with ITAM (immunoreceptor tyrosine-based activation motif) of CD3 zeta chain, labeled synthetic peptides representing the CD3 zeta chain structual motifs (ITAMs) with a tag of PKC substrate sequence were used for western blotting. One major protein band of approximately 29 kDa was identified in lysate of Jurkat T cell, B cells and HeLa cells. Screening of lamda gt 11 library derived from HeLa cell gave two clones of 14-3-3 protein cDNA. Inspection of their nucleotide sequences identified these two full length cDNA clones as the 29 kDa human homologue of rat 14-3-3 gamma and the human 14-3-3 zeta protein. The human 14-3-3 gamma isoform also showed high homology with other species in amino acid and nucleotide sequence. Although 14-3-3 proteins are phosphoserine-binding proteins, there may be another way of interaction between ITAMs of CD3 and 14-3-3 proteins.
14-3-3 Proteins
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Animals
;
B-Lymphocytes
;
Base Sequence
;
Blotting, Western
;
Clone Cells
;
Cloning, Molecular*
;
DNA, Complementary*
;
HeLa Cells
;
Humans*
;
Mass Screening
;
Peptides
;
Phosphoserine
;
Protein Isoforms
;
Rats
8.Hypertension & Sexual Function.
Journal of the Korean Medical Association 1997;40(7):847-852
No abstract available.
Hypertension*
9.Male Andropause.
Journal of the Korean Medical Association 2001;44(2):183-191
No abstract available.
Andropause*
;
Humans
;
Male*
10.Characteristics of Male Aging.
Journal of the Korean Medical Association 1998;41(9):905-914