Hereditary hypohidrotic ectodermal dysplasia is a genodermatosis that demonstrates in its typical form a triad of hypohidrosis, hypotrichosis, and hypodontia Despite marked abnormalities of ectodermal structures, reports of cataract and corneal opacity have been conspicuously rare. This paper is a report of a case which shows the typical findings of HHED, congenital cataract, and corneal opacity.
Anodontia ; Cataract* ; Corneal Opacity* ; Ectoderm ; Ectodermal Dysplasia 1, Anhidrotic* ; Hypohidrosis ; Hypotrichosis

No abstract available.

No abstract available.
Humans ; Indomethacin* ; Infant, Newborn*

No abstract available.

No abstract available.
Seizures*

A case of poorly differentiated "insular" carcinoma of the thyroid is presented and discussed with references to the literature. In fine needle aspiration cytology of our case, the aspirates were highly cellular with tumor cells appearing as dispersed isolated cells as well as in dense clusters and syncytial formations. Occasional microfollicles containing colloid were evident. Most of nuclei were fairly uniform with considerable variability and a few showed definite atypical features. Nuclear grooving was additional features. Necrotic debris was not seen. Our cytologic findings were correlated well with histology, confirming typical insular pattern of tumor cells with the presence of occasional pleomorphic cells and papillary carcinoma-like features. With much attention to cytological features of insular carcinoma, it would be possible to diagnose a preoperative suggestive diagnosis, even though not definitive.
Biopsy, Fine-Needle* ; Colloids ; Diagnosis ; Thyroid Gland*

No abstract available.
Creatinine* ; Humans ; Infant, Newborn*

PURPOSE: To compare the decentration, tilt and anterior chamber depth between aspheric AcrySof(R) IQ IOL (SN60WF) and spheric AcrySof(R) Natural IOL (SN60AT). METHODS: The subjects of this study consisted of 22 patients (26 eyes) using an aspheric AcrySof(R) IQ IOL and 26 patients (31 eyes) using spheric AcrySof(R) Natural IOL. All lenses were inserted into the capsular bag after 5 mm continuous curvilinear capsulorhexis and phacoemulsification. The decentration, tilt and anterior chamber depth of both IOLs were measured on the 1st, 30th and 60th postoperative day using an anterior eye segment analysis system (Scheimpflug camera, EAS-1000, Nidek, Japan). RESULTS: There was no statistically significant difference in the decentration between the IQ IOL and Natural IOL on the 1st (p=0.05), 30th (p=0.09) and 60th (p=0.06) postoperative day. There was a statistically significant difference in tilt between IQ IOL and Natural IOL on the 1st (p=0.000053) and 30th (p=0.018) postoperative day. However, there was no statistically significant difference in tilt on the 60th postoperative day (p=0.05). The anterior chamber depth of IQ IOL was decreased, but was not statistically significant on the 1st (p=0.10), 30th (p=0.07) or 60th (p=0.06) postoperative day. CONCLUSIONS: There were no significant differences between AcrySof(R) IQ IOL and AcrySof(R) Natural IOL in decentration, tilt or anterior chamber depth, showing that posterior aspheric surface causes little effect on the IOL stability.
Anterior Chamber ; Anterior Eye Segment ; Capsulorhexis ; Humans ; Lenses, Intraocular ; Phacoemulsification

The cystic hypersecretory duct carcinoma of the breast was first described in 1984 by Rosen and Scott and warrants separate discussion because of its unusual pathological features. It is morphologically distinguishable from juvenile (secretory) carcinoma and from mucinous (colloid) carcinoma or mucocele-like tumor. We present a case report of intraductal cystic hypersecretory carcinoma of the breast with hormone receptor and oncogene study. The histologic differential diagnosis, with an emphasis on benign lesions that may have a predominant cystic component, is also discussed.
Breast Neoplasms ; Breast* ; Diagnosis, Differential ; Mucins ; Oncogenes

PURPOSE: The C-14 urea breath test (C-14 UBT) is the most specific noninvasive method to detect Helicobacter (H) pylori infection. We investigated if the C-14 UBT can reflect the presence and degree of H. pylori detected by gastroduodenoscopic biopsies (GBx). MATERIALS AND METHODS: One hundred fifty patients (M:F=83:67, age 48.6+/-11.2 yrs) underwent C-14 UBT, rapid urease test (CLO test) and GBx on the same day. For the C-14 UBT, a single breath sample was collected at 10 minutes after ingestion of C-14 urea (137 KBq) capsule and counting was done in a liquid scintillation counter for 1 minute, and the results were classified as positive ( 200 dpm), intermediate (50~199 dpm) or negative (<50 dpm). The results of CLO tests were classified as positive or negative according to color change. The results of GBx on giemsa stain were graded 0 (normal) to 4 (diffuse) according to the distribution of H. pylori by the Wyatt method. We compared C-14 UBT results with GBx grade as a gold standard. RESULTS: In the assessment of the presence of H. pylori infection, the C-14 UBT global performance yielded sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of 92.5%, 88.4%, 97.1%, 88.4% and 91.3%, respectively. However, the CLO test had sensitivity, specificity, PPV, NPV and accuracy of 83.2%, 81.4%, 91.8%, 81.4% and 82.7%, respectively. The quantitative values of the C-14 UBT were 45+/-27 dpm in grade 0, 707+/-584 dpm in grade 1, 1558+/-584 dpm in grade 2, 1851+/-604 dpm in grade 3, and 2719+/-892 dpm in grade 4. A significant correlation (r=0.848, p<0.01) was found between C-14 UBT and the grade of distribution of H. pylori infection on GBx with giemsa stain. CONCLUSION: We conclude that the C-14 UBT is a highly accurate, simple and noninvasive method for the diagnosis of ongoing H. pylori infection and reflects the degree of bacterial distribution.
Azure Stains ; Biopsy ; Breath Tests* ; Diagnosis ; Eating ; Helicobacter pylori* ; Helicobacter* ; Humans ; Scintillation Counting ; Sensitivity and Specificity ; Urea* ; Urease