No abstract available.
Axilla ; Syringoma

BACKGROUND: Soil is one of the main habitat of fungi and important infection source of dermatophytosis. Objective: This study was performed to assess influence of dogs and horses to distribution of keratinophilic fungi (KPF) in soil. METHODS: We visited 3 dog shelters and 3 horse riding grounds in Daegu and Kyeongbuk province from September to November 2012 and examined isolation rates of fungi from 88 soil samples, 16 dogs and 16 horses. By the distance away from the animal shelters, soil samples were divided into 3 groups consist of near, 10 m and 100 m. Hair and scales from skin of the dogs and the horses were collected by Mackenzie's brush technique. RESULTS: Of the 88 soil samples examined, 35 (39.7%) yielded KPF and were all dermatophytes including Microsporum(M.) gypseum (34.1%) and Trichphyton(T.) ajelloi (5.6%). Isolation rates of KPF from the soil were observed in 79.3% of near, 40% of 10 m, and 0% of 100 m from animal shelters. Of the 16 samples from dogs, 6 (37.5%) yielded positive dermatophyte cultures and they were identified as M. canis 31.2% (5/16) and T. eboreum 6.2% (1/16). Of the 16 samples from horses, 1 (6.2%) yielded positive dermatophyte culture and it was T. eboreum. CONCLUSION: In this study, isolation rates of KPF especially M. gypseum and T. ajelloi were higher in the soil closer to the animal shelters. Soil nearby the dogs and the horses, the environment rich in keratinous material, is conducive for the growth of dermatophytes. But M. gypseum and T. ajelloi that rich in the soil were not isolated from skin of the dogs and the horses. Their pathogenicity might be low. We consider that if not human have immune deficiency or skin injury, they do not cause infection.
Animals ; Arthrodermataceae ; Daegu ; Dogs* ; Ecosystem ; Fungi* ; Hair ; Horses* ; Humans ; Methods ; Skin ; Soil* ; Tinea ; Virulence ; Weights and Measures

No abstract available.
Chancre* ; Eczema* ; Nipples*

No abstract available.
Dermatomyositis*

No abstract available.
Deglutition Disorders ; Facial Nerve ; Glossopharyngeal Nerve ; Herpes Zoster ; Herpes Zoster Oticus ; Paralysis

No abstract available.
Keratosis, Seborrheic*

Alternaria(A.) species are common saprophyte found in the environment such as soil, air, and plants. They are not usually pathogenic in humans but recently, infections by these fungi have occasionally been reported, occurring mostly in immunocompromised patients. They can cause hypersensitivity pneumonitis, bronchial asthma, or allergic rhinitis and rarely skin infection. A 76-year-old man presented with multiple erythematous papules, plaque and pustules with purpuric patches on both forearms and dorsal hands for 6 months. He had been treated for Parkinson's disease and dementia for 3 years but had not been taking any immunosuppressants. Direct smear with KOH was negative. Histopatholoigically, neutrophilic abscess, suppurative granulomatous inflammation and round spores were observed in the dermis. Periodic acid-Schiff and Methenamine silver stains revealed round to oval shaped spores. The biopsy specimen was cultured in potato dextrose agar and a cottony olive green to gray colored colony with black to brown reverse grew at 7 days of culture. The slide culture stained with lactophenol-cotton blue showed brown septated hyphae and obclavate conidia with brown muriform septation. The nucleotide sequences of the ribosomal internal transcribed spacer region of cultured colonies and paraffin blocks of biopsy specimen were identical to that of A. alternata. He was treated with topical ketoconazole cream application for 4 months, and healed leaving hyperpigmentation with scales.
Abscess ; Agar ; Aged ; Alternaria* ; Alternariosis ; Alveolitis, Extrinsic Allergic ; Asthma ; Base Sequence ; Biopsy ; Coloring Agents ; Dementia ; Dermis ; Forearm ; Fungi ; Glucose ; Hand ; Humans ; Hyperpigmentation ; Hyphae ; Immunocompromised Host ; Immunosuppressive Agents ; Inflammation ; Ketoconazole ; Methenamine ; Neutrophils ; Olea ; Paraffin ; Parkinson Disease ; Rhinitis ; Skin ; Soil ; Solanum tuberosum ; Spores ; Spores, Fungal ; Weights and Measures

Scedosporium apiospermum is an asexual state of Pseudallescheria boydii which has been isolated from soil, sewage, and decaying vegetation. It can cause cutaneous infections by traumatic implantation of the contaminant due to penetrating injury. This ubiquitous fungus cause not only mycetoma, but also infections of variety of body sites including the skin. The localized skin infection due to this organism is much rare than mycetoma. We report a case of cutaneous S. apiospermum infection occurred in 80-year-old male. The skin lesion was manifested by a 8.0 x 4.0 cm-sized erythematous plaque with pustules and crusts on the dorsum of right hand. The fungal culture from the biopsy specimen on Sabouraud's dextrose agar showed white to gray colored cottony colonies of S. apiospermum. The nucleotide sequence of internal transcribed spacer for clinical isolate was identical to that of S. apiospermum strain IHEM 23829. The patient was treated with oral fluconazole for 3 months.
Agar ; Aged, 80 and over ; Base Sequence ; Biopsy ; Fluconazole ; Fungi ; Glucose ; Hand ; Humans ; Male ; Mycetoma ; Pseudallescheria ; Scedosporium* ; Sequence Analysis, DNA* ; Sewage ; Skin* ; Soil

Clear cell acanthoma (CCA) is an asymptomatic benign lesion of unknown origin that typically appears as a brownish, dome-shaped papule on the leg. It has an unusual clinical feature in that it appears as chronic eczema, Bowen disease, or Paget disease on the areola. Its histopathologic findings are well-demarcated psoriasiform acanthosis with pale keratinocytes (clear cells) that are rich in intracellular glycogen, which stain positively with Periodic acid-Shiff. We report herein on a young female patient with CCA on the areolar areas.
Acanthoma* ; Bowen's Disease ; Eczema ; Female ; Glycogen ; Humans ; Keratinocytes ; Leg ; Nipples

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematopoietic malignancy which is derived from the precursors of plasmacytoid dendritic cells and is more infrequent in children than in adults. Formerly known as blastic NK-cell lymphoma or CD4+/CD56+ hematodermic neoplasm, the BPDCN is reclassified into the group of acute myeloid leukemia and related neoplasm by WHO in 2008. An 8-year old girl is being presented with bruise-like subcutaneous nodules with purpura on her right cheek from the performed biopsy. Histological examinations show sheet-like dense infiltrations of medium-sized lymphoid cells with irregular nuclei in the entire dermis. Immunohistochemical stainings of tumor cells were positive for CD4, CD56, LCA, TCL-1, TdT and focal positive for CD3, CD7, CD45RO and negative for CD20, CD30, CD34, EBV. The PET-CT scans indicate hot uptakes in the bone marrows which are suggestive of malignant infiltrations, and bone marrow biopsy findings are consistent with BPDCN of leukemic transformations. We present a rare case of BPDCN which affects the pediatric patient.
Adult ; Biopsy ; Bone Marrow ; Cheek ; Child* ; Dendritic Cells* ; Dermis ; Female ; Hematologic Neoplasms ; Herpesvirus 4, Human ; Humans ; Leukemia, Myeloid, Acute ; Lymphocytes ; Lymphoma ; Purpura