The authors treated 12 patients with pseudophakic endophthalmitis over a 5 year period between 1990 and 1994. Common clinical manifestations included anterior chamber inflammation, conjunctival injection, decreased visual acuity, ocular pain and hypopyon. Eight of 12 cases(67%) were culture positive when organisms were grown up from aspirates of the aqueous, the vitreous or both. Three of the culture positive cases were grown up from aspirates of the aqueous, the vitreous or both. Three of the culture positive cases were candida endophthalmitis. Treatment consisted of topical, periocular, systemic and intravitreal injection of antimicrobial agents. In addition, because of poor clinical response of medical conservative therapy, six cases had a vitrectomy. Intraocular lenses were removed in 3 candida endophthalmitis at second operation. Final visual acuity has better in culture negative and low virulent bacterial endophthalimitis than high virulent bacterial and candida endophthalmitis. Visual outcome was better in cured patients who received a single intravitreal injection or a single intravitreal injection in combination with virectomy than the patients who did not receive intravitreal injection or received repeated intravitreal injection. Complications were two eviscerations and a retinal detachment.
Anterior Chamber ; Anti-Infective Agents ; Candida ; Endophthalmitis* ; Humans ; Inflammation ; Intravitreal Injections ; Lenses, Intraocular ; Pseudophakia ; Retinal Detachment ; Visual Acuity ; Vitrectomy

PURPOSE: To report the results of strabismus surgery in five patients diagnosed with myasthenia gravis with strabismus. CASE SUMMARY: The authors retrospectively analyzed the effect and timing of surgery for patients who developed strabismus after being diagnosed for myasthenia gravis. Cases 1 and 2 were female myasthenia gravis patients, eight and 45 years of age, who underwent surgery after symptoms developed for correction of exotropia at 33 months and ten years after diagnosis, respectively. Case 3 was a 33-year-old male hyperthyroidism patient who had an exotropia operation six years after his strabismus diagnosis. Cases 4 and 5 were a 22-year-old female and a 50-year-old male patient, who underwent surgery for correction of left hypotropia at 14 months and ten months after diagnosis, respectively. Eventually, a total of three cases of horizontal deviation and two cases of vertical deviation had successful outcomes resulting within ten prism diopters. The patients in cases 4 and 5, both of whom had vertical deviations, experienced a short wait time from the date of symptom presentation until they were able to receive surgery. In particular, case 5 developed left hypertropia two months prior to surgery and the strabismus angle increased until six months prior to surgery. However, the hypertropia stabilized afterwards and the patient finally obtained orthophoria after a left inferior rectus advancement operation. CONCLUSIONS: In patients diagnosed with myasthenia gravis and a large angle strabismus, a longer follow-up period from diagnosis to operation is necessary for a successful postoperative outcome and stable strabismus angle.
Adult ; Exotropia ; Female ; Follow-Up Studies ; Humans ; Hyperthyroidism ; Male ; Middle Aged ; Myasthenia Gravis ; Retrospective Studies ; Strabismus ; Young Adult

On histological examination, an epidermolytic hyperkeratosis was observed adjacent to follicular papules on the back of a 53-year-old man. It has been reported that incidental epidermolytic hyperkeratosis occur either within various lesion (epidermal neoplasm, melanocytic neoplasm, scars, and inflammatory conditions) or in the normal skin adjacent to the lesion. This patient participated in the Vietnam War for 2 years, and had had contact with defoliants. He was treated for multiple peripheral neuropathies and cerebral infarcts. In keratinocytes, 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD; Agent Orange) contained in defoliating agents is associated with altered patterns of keratinocyte differentiation. So, as a cause of incidental epidermolytic hyperkeratosis, defoliant contact could be suspected.
Cicatrix ; Humans ; Hyperkeratosis, Epidermolytic* ; Keratinocytes ; Middle Aged ; Peripheral Nervous System Diseases ; Skin* ; Tetrachlorodibenzodioxin ; Veterans* ; Vietnam*

No abstract available.
Retroperitoneal Fibrosis*

No abstract available.
Hand Strength*

We performed a clinicopathological study of nineteen patients with chronic inflammatory nodose lesions of the legs which responded to the treatment with isolniazid. The results were summarized as follows: 1. Seven patients had a personal or family history of tuberculcsis and all patients showed a high tuberculin sensitivity. But, no one showed the evidence of active pulmonary tuberculosis. 2. The inflammatory nodules and swelling of the legs were resolved within 12 months in all cases. Resolution of the nodules was more rapid than that of leg swelling. 3. The clinical characteristics of the patients with chronic inflanimatory nodules were the same as those of the cases with erythema nodosum or erytiema induratum reported previously in Korea. The basic histopathologic process of inflarr matory nodules seemed to be vasculitis.
Erythema Nodosum ; Humans ; Isoniazid* ; Korea ; Leg* ; Tuberculin ; Tuberculosis, Pulmonary ; Vasculitis

No abstract available.
Candidiasis* ; Paget Disease, Extramammary* ; Vulva

No abstract available.
Dermoid Cyst*

Creutzfeldt-Jakob disease (CJD) is one of the transmissible spongiform encephalopathies, which is mediated by what has been known as "prion". It is a rare and fatal progressive neurodegenerative disease that affects the middle and old aged. There are a number of subtypes of CJD, one of which is the sporadic type characterized by rapidly progressing clinical symptoms, including progressive dementia, myoclonic jerk, and pyramidal or extrapyramidal syndrome. Patients usually end up dying within 1 to 2 years of contacting the disease. We report an autopsy-proven case of sporadic CJD with clinical symptoms that progressed within several days, along with dramatic changes on diffusion weighted magnetic resonance images.
Brain ; Creutzfeldt-Jakob Syndrome ; Dementia ; Diffusion ; Humans ; Myoclonus ; Neurodegenerative Diseases ; Prion Diseases

A patients with atlantoaixial instability and osodontoideum underwent atlantoaixial fusion (Harms and Melcher technique) with demineralized bone matrix. But, unfortunately, the both pedicle screws in C2 were fractured within 9 weeks follow-up periods after several suspected episode of neck hyper-flexion. Fractured screws were not contact to occipital bone in several imaging studies, but it could irritate the occipital bone when neck extension because the relatively close distance between the occipital bone and C1 posterior arch. The patient underwent revision operation with translaminar screw fixation with autologus iliac bone graft. Postsurgical course were uneventful except donor site pain, but the bony fusion was not satisfied after 4 months follow-up. The patient re-underwent revision operation in other hospital. Continuous complication after atlantoaixial fusion is rare, but the clinical course could be unlucky to patients. Postoperative immobilization could be important to prevent the unintended clinical course of patients.
Bone Matrix ; Follow-Up Studies ; Humans ; Immobilization ; Neck ; Occipital Bone ; Tissue Donors ; Transplants