No abstract available.
Animals ; Rats* ; Superoxide Dismutase* ; Superoxides*

No abstract available.
Cartilage* ; Glutaral* ; Rabbits* ; Transplants*

No abstract available.
Pancreas*

No abstract available.
Humerus*

OBJECTIVE: This study was designed for developing a new experimental animal model of Wernicke's encephalopathy, and for investigating the timesequential morphological changes in the thiamine deficient rat brain by thiamine deficient diet with short term treatment of pyrithiamine. METHODS: A total of 40 healthy Sprague-Dawley strain rats, weighing about 2OOgm were used as experimental animals, divided into 10 control rats and 30 thiamine deficient experimental rats. Pyrithiamine (50mg/lOOgm/day) was injected intraperitonially for 9 days and thiamine deficient diet (20gm/rat/day) was continuously supplied until sacrifice. Then thiamine deficient experimental rats were subdivided into 3 groups according'to the exposure time of thiamine deficiency. For observing the morphological features in thalamus, medial mammillary nucleus and CA, sector in hippocampus, luxol-fast blue-cresy violet stain was performed. RESULTS: Treatment with pyrithiamine and thiamine deficient diet results in weight loss and decrement of body temperature on the 12th-14th day, followed by various neurologic manifestations, such as ataxia, hypotonia, circling movement, opisthotonus and loss of righting reflex, on the 16th-20th day, and then died on the 23th-25th, day. Chromatolysis and nuclear condensation of neurons in thalamus, medial mammillary nucleus and CA1 region of hippocampus are observed in group I. Mild edematous changes with neuronal necrosis in group II, and marked neuronal loss with severe edematous necrosis in group III are noted in same regions. CONCLUSION: These time sequential consistent morphological changes suggest that our experimental method could be used as a new animal model of Wernicke's encephalopathy in studying the sequential changes of thiamine deficient rat brain.
Animals ; Ataxia ; Body Temperature ; Brain ; Diet* ; Hippocampus ; Models, Animal ; Muscle Hypotonia ; Necrosis ; Neurologic Manifestations ; Neurons ; Prosencephalon* ; Pyrithiamine* ; Rats* ; Rats, Sprague-Dawley ; Reflex, Righting ; Thalamus ; Thiamine Deficiency ; Thiamine* ; Viola ; Weight Loss ; Wernicke Encephalopathy

No abstract available.

No abstract available.
Synostosis*

Since Maisonneuve mentioned osteomyelitis complicated by typhoid fever for the first time in 1835, numerous investigators had reported salmonella osteomyelitis. The authors recently experienced six cases of salmonella osteomylitis: four cases in lumbar spine and the remainders in bones adjacent to elbow. Four cases were in adult male ranging from 18 to 35 years old and the others were in a male, age of thirteen and female, age of seven in elbow respectively. The two among four spondylitic cases and two cases of long bone ostemyelitis were surgically treated, and the other two spondylitic cases were conservatively treated. Salmonella osteomylitis was confirmed in surgically treated group by culture of pus obtained from pathologic lesion, and conservatively treated group was diagnosed by history, clinical manifestation, laboratory data and especially characteristic progress of roentgenographic change. The causative organisms were paratyphoid group D in all cases. Review of literature was done with report of six cases of salmonella osteomyelitis.
Adult ; Elbow ; Female ; Humans ; Male ; Osteomyelitis ; Research Personnel ; Salmonella ; Spine ; Suppuration ; Typhoid Fever

Purpose: To evaluate the surgical outcomes of a modified normogram for bilateral lateral rectus recession in the surgical management of intermittent exotropia, with a focus on achieving small overcorrection. Methods: A retrospective medical chart review of 242 patients who underwent surgery for intermittent exotropia between October 2014 and June 2020 was performed. Our modified normogram reducing amount of recession targeted for small postoperative overcorrection within 5 prism diopters (PD). Patients were observed for at least 3 years. Esodeviation was denoted by negative numbers and positive values indicated exodeviation. A satisfactory outcome was defined as if distant angle of deviation ranged between ≤10 PD of exotropia and ≤5 PD of esotropia. Recurrence was defined as an exodeviation of >10 PD at distance. Overcorrection was defined as an esodeviation of >5 PD at distance. Results: The mean preoperative deviation angles were 29.32 ± 3.92 PD at distance and 29.88 ± 4.41 PD at near. At postoperative day 1, the mean deviation angles at distance and near were –6.22 ± 1.44 and –6.22 ± 1.49 PD, respectively. Overcorrection within 6 PD of esodeviation was seen in 168 patients (69.42%), undercorrection with exophoria was noted in 11 patients (4.55%), and overcorrection by more than 6 PD of esodeviation was seen in 63 patients (26.03%) at postoperative day 1. The long-term success rate at postoperative 3 years was 77.27% (187 of 242), with a recurrence rate of 19.83% (48 of 242) and an overcorrection rate of 2.89% (7 of 242). A positive correlation between the angle of deviation at postoperative day 1 and 3 years was observed (r = 0.22, p = 0.001). The final success rate at the final examination after a mean follow-up of 38.60 ± 7.99 months was 83.06%. Conclusions Our modified normogram for bilateral lateral rectus recession in intermittent exotropia surgery resulted in successful surgical outcomes with small overcorrection, reducing the risk of consecutive esotropia due to excessive overcorrection.

Purpose: To evaluate the surgical outcomes of a modified normogram for bilateral lateral rectus recession in the surgical management of intermittent exotropia, with a focus on achieving small overcorrection. Methods: A retrospective medical chart review of 242 patients who underwent surgery for intermittent exotropia between October 2014 and June 2020 was performed. Our modified normogram reducing amount of recession targeted for small postoperative overcorrection within 5 prism diopters (PD). Patients were observed for at least 3 years. Esodeviation was denoted by negative numbers and positive values indicated exodeviation. A satisfactory outcome was defined as if distant angle of deviation ranged between ≤10 PD of exotropia and ≤5 PD of esotropia. Recurrence was defined as an exodeviation of >10 PD at distance. Overcorrection was defined as an esodeviation of >5 PD at distance. Results: The mean preoperative deviation angles were 29.32 ± 3.92 PD at distance and 29.88 ± 4.41 PD at near. At postoperative day 1, the mean deviation angles at distance and near were –6.22 ± 1.44 and –6.22 ± 1.49 PD, respectively. Overcorrection within 6 PD of esodeviation was seen in 168 patients (69.42%), undercorrection with exophoria was noted in 11 patients (4.55%), and overcorrection by more than 6 PD of esodeviation was seen in 63 patients (26.03%) at postoperative day 1. The long-term success rate at postoperative 3 years was 77.27% (187 of 242), with a recurrence rate of 19.83% (48 of 242) and an overcorrection rate of 2.89% (7 of 242). A positive correlation between the angle of deviation at postoperative day 1 and 3 years was observed (r = 0.22, p = 0.001). The final success rate at the final examination after a mean follow-up of 38.60 ± 7.99 months was 83.06%. Conclusions Our modified normogram for bilateral lateral rectus recession in intermittent exotropia surgery resulted in successful surgical outcomes with small overcorrection, reducing the risk of consecutive esotropia due to excessive overcorrection.