2.Pulmonary Metastasis of Malignant Meningioma.
Jong Kook RHIM ; Seung Hun SHEEN ; Jae Sub NOH ; Bong Sub CHUNG
Journal of Korean Neurosurgical Society 2004;35(5):533-535
We report a case of 41-year-old male with pulmonary metastasis from a recurrent intracranial malignant meningioma, which had two more recurrence, multiple intracranial metastasis. Pulmonary metastasis was developed five years after resection of primary lesion. The metastatic routes and treatment of pulmonary metastatic malignant meningiomas were described.
Adult
;
Humans
;
Male
;
Meningioma*
;
Neoplasm Metastasis*
;
Recurrence
3.The direct effects of progesterone/progestin on vascular tone.
Soo Hyun CHO ; Seung Ryong KIM ; Kyoung Hun KIM ; Jung Kook SUH
Korean Journal of Obstetrics and Gynecology 2001;44(7):1232-1236
OBJECTIVES: To evaluate the effects of progesterone/progestin and in combination with estrogen in relaxation of rat aorta. METHODS: Eight weeks after bilateral oophorectomy, the descending aorta of Spague-Dawley rats (n=10) were quickly removed and placed in organ bath containing Krebs solution. Each aorta ring in 2-3 mm length was connected to an isometric force transducer (FT 03, Grass, USA) and the changes in tension were recorded with an AD converter system (MP 100, Biopac Inc, USA) in a personal computer. After precontraction of the rings with norepinephrine (1 umol/L) or KCl (40 mmol/L), estradiol, progesterone, medroxyprogesterone acetate (MPA), norethisterone acetate (NETA) (10-5-10-8 M/L in each) were added to each ring and they were incubated for 15 minutes. The relaxation was expressed as a percentage of the tonic contraction. RESULTS: Estrogen relax the aorta in all concentrations. The degree of relaxation was dose dependent (P<0.001). All of the progesterone, MPA, NETA relax the aorta and the effects was different according to the concentration of steroids (P<0.0001). The degree of relaxation was not different between estrogen and those of progesterone, MPA, NETA except MPA 10-8 M, NETA 10-5 M. Addition of progesterone, MPA and NETA to the estrogen showed similar vascular effects compared to those of estrogen alone. CONCLUSION: Not only estrogen but also progesterone, MPA, and NETA acutely relax aorta. Progesterone/progestin have not been found attenuate the action of estrogen in our animal in vitro study.
Animals
;
Aorta
;
Aorta, Thoracic
;
Arteries
;
Baths
;
Estradiol
;
Estrogens
;
Female
;
Medroxyprogesterone Acetate
;
Microcomputers
;
Norepinephrine
;
Norethindrone
;
Ovariectomy
;
Poaceae
;
Progesterone
;
Rats
;
Relaxation
;
Steroids
;
Transducers
4.Endotracheal Intubation with Laryngeal Mask Airway and Fiberoptic Bronchoscope.
Jong Hun JUN ; Ik Sang SEUNG ; Sang Yoon CHO ; Jung Kook SUH
Korean Journal of Anesthesiology 1993;26(5):1029-1034
It is easy to view the laryngeal aperature with a flexible fiberscope through a laryngeal mask airway (LMA). This is a case report that the LMA could facilitate a fiberscope-aided tracheal intubation easily. Patient was a 59 year old female who had some limitation of mouth opening due to ankylosis of bilateral temporomandibular joints. After thiopental (200 mg) and succinylcholine chloride (50 mg) were given intravenously, a number 3 sized LMA was inserted and the lungs were ventilated via the LMA. The anesthesia cirele system is then disconnected from the LMA and a fiberscope, with the proximal end jacketed with a well-lubricated, cuffless, 6-mm-ID endotracheal tube (ETT); was inserted into the trachea through the lumen of the LMA. The 6-mm-ID ETT was threaded over the fiberscope into the trachea before fiberscope was withdrawn, and a traeheal tube exchanger was inserted through the ETT after enough ventilation for a while, followed withdrawal of the LMA and ETT. Finally, we can make the 7 mm-ID ETT with cuff insert into the trachea over a tracheal tube exchanger very easily without any difficulties.
Anesthesia
;
Ankylosis
;
Bronchoscopes*
;
Female
;
Humans
;
Intubation
;
Intubation, Intratracheal*
;
Laryngeal Masks*
;
Lung
;
Middle Aged
;
Mouth
;
Succinylcholine
;
Temporomandibular Joint
;
Thiopental
;
Trachea
;
Ventilation
5.A Case of Pelvic Actinomycosis Associated with Intrauterine Contraceptive Device.
Seung Hun LEE ; Jin Wan PARK ; Na Hye MYONG
Korean Journal of Obstetrics and Gynecology 2002;45(3):516-519
Actinomycosis is a subacute-to-chronic infection caused by gram-positive, anaerobic bacteria. Actino- mycetes reside in oral cavity, gastrointestinal tract, female genital tract as normal flora, but may provoke an opportunistic infection under certain circumstances, resulting in contiguous spread, suppurative and granu- lomatous inflammatory reaction, and formation of multiple abscesses. Abdominal and pelvic actinomycosis in women are related to a history of abdominal surgery or intrauterine contraceptive device (IUD) insertion and have variable nonspecific symptoms that make an initial diagnosis difficult. We experienced a case of pelvic actinomycosis related to IUD that diagnosed pathologically after laparotomy.
Abscess
;
Actinomycosis*
;
Bacteria, Anaerobic
;
Diagnosis
;
Female
;
Gastrointestinal Tract
;
Humans
;
Intrauterine Devices*
;
Laparotomy
;
Mouth
;
Opportunistic Infections
6.Influence of immediate loading on the removal torque value of mini-screws.
Seung Bum SUN ; Yoon Goo KANG ; Seung Hun KIM ; Sung Seo MO ; Yoon Ah KOOK
Korean Journal of Orthodontics 2007;37(6):400-406
OBJECTIVE: The purpose of this experimental study was to evaluate the effect of immediate orthodontic loading on the stability at the bone-implant interface of titanium miniscrews in a rabbit model. METHODS: Forty titanium miniscrews (1.6 mm diameter, 8 mm length) were inserted in the tibiae of 10 rabbits. Twenty test group miniscrews were subjected to continuous orthodontic forces of 200 g immediately after implantation for a period of 6 weeks. The remaining 20 control group miniscrews were left unloaded for the same follow-up interval. Removal torque values were recorded using a digital torque gauge. An independent t-test was performed. RESULTS: All the miniscrews were stable, and exhibited no mobility or displacement throughout the experimental period. Histologically, miniscrews were well-integrated into bone. No statistically significant differences in removal torque data were found between the loaded test and the unloaded control groups. CONCLUSIONS: These findings suggest that titanium miniscrews can be used as anchoring units for orthodontic tooth movement immediately after insertion.
Follow-Up Studies
;
Rabbits
;
Tibia
;
Titanium
;
Tooth Movement
;
Torque*
7.A Case of Acute Twin-Twin Transfusion Syndrome.
Eun A CHOI ; Ji Hee RYU ; Tae Lim JOO ; Soon Mi CHOI ; Seung Hun LEE ; Kyung SEO ; Kook LEE
Korean Journal of Obstetrics and Gynecology 1997;40(10):2285-2289
Twin-twin transfusion syndrome(TTTS) is a serious complication of monozygotic mu-ltiple pregnancy. TTTS is associated with high perinatal mortality rate. The acute form has been attributed to rapid transfer of blood through superficial artery-to-artery or vein-to- vein anastomoses during labor and delivery, resulting in a hypovolemic, anemic donor twin and a hypervolemic, plethoric recipient twin of similar birth weight. The authors present a case of acute twin-twin transfusion syndrome with a review of literature.
Birth Weight
;
Humans
;
Hypovolemia
;
Perinatal Mortality
;
Pregnancy
;
Tissue Donors
;
Veins
8.Brain Stem Gliomas in Adult: Correlation between MRI, Clinical Findings and Outcome: Preliminary Report.
Ji Soo JANG ; Jin Kook KIM ; Jae Wook SONG ; Sang Min YOUN ; Chang Hun RHEE ; Seung Hoon LEE
Journal of Korean Neurosurgical Society 1997;26(4):518-525
An analysis of 13 patients with brain stem glioma in adult, treated between 1988 and 1995, was undertaken. The purpose of this study is to establish the correlations between the MRI appearance, clinical findings and the prognosis. Based on the MRI appearance of the tumor at the time of clinical diagnosis, tumors were divided into four types: intrinsic diffuse, intrinsic focal, intrinsic cervicomedullary and exophytic type. Five patients were diagnosed pathologically by means of stereotactic biopsy(2 patients) and open surgery(3 patients), the rest were diagnosed on the basis of MRI appearance. All patients had received radiation therapy, and 11 patients had received chemotherapy during or immediately after radiation therapy. The methods of radiation therapy were either conventional or hyperfractionated type. The histological features were not always correlated with the prognosis. MRI and clinical findings could suggest the prognosis and probably the histological nature of the tumors. Moreover, response to initial radiotherapy and chemotherapy was considered to be a good prognostic factor. Seven of the 13 patients had response to the initial radiotherapy and chemotherapy. The poor prognostic factors determined in our study were 1) diffuse type 2) rapid growing with rim enhancement in spite of initial radiotherapy and chemotherapy 3) malignant pathologic finding 4) intratumoral necrosis after radiotherapy 5) multiple site involvement. The good prognostic factors were 1) intrinsic focal type 2) intrinsic cervicomedullary type 3) no cranial nerve involvement 4) good response to initial radiotherapy and chemotherapy.
Adult*
;
Brain Stem*
;
Brain*
;
Cranial Nerves
;
Diagnosis
;
Drug Therapy
;
Glioma*
;
Humans
;
Magnetic Resonance Imaging*
;
Necrosis
;
Prognosis
;
Radiotherapy
9.Neuromuscular Block by Vecuronium and its Reversal with Pyridostigmine in Rabbits.
Kyoung Hun KIM ; Dong Ho LEE ; Kyo Sang KIM ; Jung Kook SUH ; Hee Koo YOO ; Ik Sang SEUNG ; Se Ung CHON
Korean Journal of Anesthesiology 1988;21(2):307-312
Despite the fact that the anticholinesterases, mainly neostigmine, has been used for many years to antagonize a nondepolarizing neuromuscular blockade, until recently nothing was known about their pharmacokinetics and dynamics in anesthetized patients. This deficiency was largely due to lack of a suitable analytic technique to measure the concentration of these drugs in body fluids, most importantly serum. Recently it was developed a method by which the serum concentrations of neostigmine, pyridostigmine, edrophonium and their metabolities can be measured. Recently,k pyridostigmine and edrophonium have gained popularity to use for reversing a nondepolarizing muscle relaxants. We have studied newly introduced vecuronium effects and its reversal with pyridostigmine. The results were as follows: 1) Spontaneous recovery index by vecuronium 0.1mg/kg was 620.8 sec. 2) Recovery index by the pyridostigmine 160ug/kg reversal was significantly shortened as 134.0sec in vecuronium 0.1mg/kg block. 3) Tetanic stimulation (100Hz, 5sec) was sustained after 75% recovery of twitch height by pyridostigmine 160ug/kg reversal.
Body Fluids
;
Cholinesterase Inhibitors
;
Edrophonium
;
Humans
;
Neostigmine
;
Neuromuscular Blockade*
;
Pharmacokinetics
;
Pyridostigmine Bromide*
;
Rabbits*
;
Vecuronium Bromide*
10.Aneurysm of the Posterior Inferior Cerebellar Artery: Clinical Features and Surgical Results.
Jong Kook RHIM ; Seung Hun SHEEN ; Sung Han OH ; Jae Sub NOH ; Bong Sub CHUNG
Journal of Korean Neurosurgical Society 2005;37(6):399-404
OBJECTIVE: Aneurysms arising from the posterior inferior cerebellar artery(PICA) are uncommon. We review literature on that and surgical results on aneurysmal treatment by choice of surgical approach. METHODS: On the basis of radiologic findings & charts, we review retrospectively the surgical results of 12 cases from Mar 1999 to Dec 2003. RESULTS: The mean age of the 12 patients was 55.8(ranged from 36 to 71) and female was predominant (female: male=8: 4). Locations of PICA aneurysms revealed variously(vertebral artery-PICA junction: 8, lateral medullary segment: 2, PICA-anterior inferior cerebellar artery common trunk: 1, telovelomedullary: 1). Surgical approaches & treatments were attempted in 11 cases and embolization was done in 1 case(Far lateral transcondylar or supracondylar approach & clipping: 9, Far lateral transcondylar or supracondylar approach and trapping: 2, suboccipital approach & clipping: 1). The surgical result were 8 of 12 patients were good outcome, 1 of 12 was severely disabled and 3 of 12 were died. CONCLUSION: First, we choose surgical approach by the laterality of aneurysms and surgical or interventional treatment is attempted as soon as possible. The PICA aneurysm is regarded as having a relatively good surgical outcome without drilling of the posterior arch of the atlas.
Aneurysm*
;
Arteries*
;
Female
;
Humans
;
Pica
;
Retrospective Studies