1.The Role of Medical Personnel in a Disaster.
Journal of the Korean Medical Association 2001;44(6):588-595
No abstract available.
Disasters*
2.Post Traumatic Radioulnar Cross Union: A Case Report
The Journal of the Korean Orthopaedic Association 1971;6(2):143-145
The purpose of this paper is to report the rare complicated radioulnar cross union following open reduction for fractures of the forearm bones. The case was 62 years old male who complained of swelling and pain on forearm by the car accident. Roentgenogram revealed forearm bones fracture. Atpost operative 4 months, roentgenogram noted new bone crossing between radius and ulna. Excision of new bane was performed with extraction of nail and inserted chips of muscle. Post operative course was satisfactory, showing 50 degree of range of motion (20 degree supination and 30 degree pronation) from fixed pronation position.
Forearm
;
Humans
;
Male
;
Pronation
;
Radius
;
Range of Motion, Articular
;
Supination
;
Ulna
3.Effect of Human Seminal Plasma on Cytokine Prodection and Induction of Active Systemic Anaphylaxis in Mice.
Tai You HA ; Jae Seung PARK ; Yoo Seung KO ; Yong Ho LEE ; Young Kyung PARK
Korean Journal of Immunology 1999;21(3):209-219
Human seminal plasrna (HSP) is mixture of secretion derived from various glands associated with male reproductive tract which comprises approximately 80-90% of the volume of normal ejaculate. The present study was undertaken in an effort to explore the effect of HSP pretreatment on the production of IL-1B, TNF-a and IL-12, in mice, and to investigate if HSP may cause to induce active systemic anaphylaxis (ASA) in mice. In addition, effects of HSP pretreatment on contact hypersensitivity to trinitrochlorobenzene (TNCB), antibody response to polyvinylpyrroridone (PVP), a thymus-independent antigen and on ASA induced by egg albumin (OVA) were also studied in this study. For the experiments of contact hypersensitivity, antibody response and cytokine production, mice were pretreated i.p. daily with 0.3ml of HSP or sterile saline alone (control) for 3 consecutive days before antigen sensitization or lipopolysaccharide injection for the cytokine induction. For the experiments of OVA- induced anaphylaxis, mice were pretreated by a single s.c. injection of HSP 0.3ml per mouse before sensitization. For induction of ASA in mice by HSP, a group of mice were sensitized i.p. 2 consecutive days with 0.3ml of HSP and one day with 0.3 ml of HSP plus 2x10(9) B. pertussis and 1.0 mg of alum (schedule A) or another group of mice were sensitized i.p. with a single i.p. injection of 0.3 ml of HSP with 2x10' B. pertussis and 1.0 mg of alum (schedule B). All sensitized and unsensitized control mice were challenged i.v. with 0.2ml of HSP 14 days after HSP sensitization, and mortality were observed. It was found that HSP pretreatment inhibited the production of IL-lB, TNF-a and IL-12, and also inhibited OVA-induced ASA, contact hypersensitivity to TNCB and anti-PVP antibody production. Interestingly, ASA was induced by HSP irrespective of the applied sensitization schedule. Taken together, this study may provide the direct evidences that HSP may inhibit the production of IL-1B, TNF-a and IL-12 and this may be the first to show the induction of ASA by HSP in mice.
Anaphylaxis*
;
Animals
;
Antibody Formation
;
Appointments and Schedules
;
Dermatitis, Contact
;
Humans*
;
Interleukin-12
;
Male
;
Mice*
;
Mortality
;
Ovum
;
Picryl Chloride
;
Semen*
;
Whooping Cough
4.Minimal Change of Lymphocyte Subsets in 24 Hours-Stored Whole Blood Sample.
Hyun Soo KIM ; Seung Ho LEE ; Myoung Hee PARK
Korean Journal of Clinical Pathology 1997;17(2):331-338
BACKGROUND: In recent years, lymphocyte subset analysis in peripheral blood is widely performed using erythrocytes-lysed whole blood and two color immunofluorescence/flow cytometry method. Use of fresh blood drawn within 6 hours of staining is recommended, and some patients have to revisit the hospital for blood collection. We tested whether 24 hours-refrigerated/stored whose blood can be used for lymphocyte subset analysis. METHODS: Twenty consecutive blood samples from patients (including nine HIV positive patients) collected in EDTA-vacutainer were tested: 1) on the day of sampling using fresh blood kept at room temperature for up to 6 hours until staining (as recommended by the manufacturer) and 2) on the following day using the same tube of blood refrigerated for 24 hours after the first staining. Two colon immunofluorescenc staining was done using Simultest(TM) IMK-Lymphocyte kit (Beckon Dickinson, U.S.A.) and flow cytometric analysis was performed using FACScan and SimulSET(TM) software (Becton Dickinson, U.S.A.). Results of alive kinds of Lymphocyte subsets (CD3+, CDl9+, CD3+CD4+CD3+CD8+, CD3-CDl6+ and/or CD56+) on day 1 and day 2 were compared by pained-t test and Wilcoxon signed rank test. RESULTS: There was no significant change of values for all of the lymphocyte subsets except CD3+CD8+suppressor/cytotoxic (S/C) T cells. There was a slight but statistically significant change in S/C T cells (39.9%-->41.8%: 1.9%, p=0.008) after 24 hours of refrigeration, and this change was observed mainly in HIV-positive patient group. However, there was no significant change in the absolute count of helper/inducer T cells or CD4/CD8 ratio, and the change of S/C T cells in these patients was not considered to be of clinical significance. CONCLUSIONS: The difference in the values of lymphocyte subsets between fresh blood and 24 hours-refrigerated blood was negligible and it is concluded that 24 hours-stored blood samples can be used for lymphocyte subset analysis for clinical purposes.
Colon
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HIV
;
Humans
;
Lymphocyte Subsets*
;
Lymphocytes*
;
Refrigeration
;
T-Lymphocytes
5.A 20 years, experience with well differentiated thyroid carcinoma in children & teenagers.
Jae Sub PARK ; Seung Hoon CHOI ; Eu Ho HWANG
Journal of the Korean Cancer Association 1991;23(3):640-647
No abstract available.
Adolescent*
;
Child*
;
Humans
;
Thyroid Gland*
;
Thyroid Neoplasms*
6.A Case of Currarino Triad.
Seung Mo PARK ; Duk Hi KIM ; Ho Seong KIM
Journal of the Korean Pediatric Society 1994;37(8):1169-1174
Currarino triadis a unique malformation complex of congenital caudal anormalies, including anorectal malformatio (anal stenosis, anal ectopis, imperforated anus), sacral bony abnormality (scimitar or crescentic bony defect, malsegmentation) and presacral mass (meningocele, teratoma, enteric cyst or any combination of these). This triad is familial in at least half of cases and the usual symptomatology is constipation due to anorectal stenosis. The embryogenesis is presumably due to abnormal separation of the neuroectoderm from the endoderm, so this triad is in the spectrum of the split notochord syndrome. We report a case of Currarino triad in 5-month-old female patient who had chronic constipation and abdominal distention with brief review of the related literatures.
Constipation
;
Constriction, Pathologic
;
Embryonic Development
;
Endoderm
;
Female
;
Humans
;
Infant
;
Neural Plate
;
Notochord
;
Pregnancy
;
Teratoma
7.A case of disseminated superficial porokeratosis in immunosuppressed kidney transplant recipient.
Young Ho CHO ; Seung Kyung HANN ; Yoon Kee PARK
Korean Journal of Dermatology 1992;30(4):539-542
Porokeratosis is an uncommon autosomally dominant inher ted disorder. Clinically, it is characterized by nonhealing plaques that develop most comnorly on the limbs. We report a case of disseminated superficial porokeratosis in immunosuppre sed kidney transplant recipient. An abrupt and extensive eruption of porokeratosis was observed in a 46-year-old man 7 months after renal transplantation, while being treated with cyclosporin A and prednisone. The histological features were essentially the same as the typical cornoid lamella. Immunosuppression may exacerbate or initiate the developm nt of porokeratosis in patients predisposed to alterations of cutaneous growth dynamics.
Cyclosporine
;
Extremities
;
Humans
;
Immunosuppression
;
Kidney Transplantation
;
Kidney*
;
Middle Aged
;
Porokeratosis*
;
Prednisone
;
Transplantation*
9.The effects of long-term lithium treatment on the parathyroid hormone and calcium level.
In Joon PARK ; Seung Hyun KIM ; Sun Ho HAN
Journal of Korean Neuropsychiatric Association 1991;30(6):974-981
No abstract available.
Calcium*
;
Lithium*
;
Parathyroid Hormone*
10.Alcohol and Sleep.
Doo Heum PARK ; Jaehak YU ; Seung Ho RYU
Sleep Medicine and Psychophysiology 2006;13(1):5-10
Alcohol has extensive effects on sleep and daytime sleepiness. Alcohol has a sleep inducing effect and the effect of increased non-REM sleep and suppressed REM sleep during the first half portion of night sleep, but alcohol induces the effect of decreased non-REM sleep and increased light sleep and frequent awakenings and REM rebound during the second half portion of night sleep. Alcohol provokes chronobiological change such as the changes of amplitude or the phase shifts of hormones or core body temperature. The sleep disruption resulting from alcohol drinking may lead to daytime fatigue and sleepiness. The elderly are at particular in the increased risk of alcohol-related sleep disorders because they achieve higher levels of alcohol in the blood and brain than do younger adults after consuming an equivalent dose. Bedtime alcohol consumption among older adults may lead to unsteadiness if walking is attempted during the night, with increased risk of falls and injuries. Continued alcohol use for sleep induction often induces aggravation of insomnia, alcoholism or sleep related breathing disorders such as obstructive sleep apnea. Alcohol should not be used as substitution of sleep pill because of the dependence and tolerance for sleep inducing effect, and the sleep disruption produced by alcohol withdrawal.
Adult
;
Aged
;
Alcohol Drinking
;
Alcoholism
;
Body Temperature
;
Brain
;
Fatigue
;
Humans
;
Respiration
;
Sleep Apnea, Obstructive
;
Sleep Wake Disorders
;
Sleep Initiation and Maintenance Disorders
;
Sleep, REM
;
Walking